2n6h - Revision history

OCA at 08:37, 15 November 2023

OCA — Wed, 15 Nov 2023 08:37:30 GMT

←Older revision		Revision as of 08:37, 15 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6H FirstGlance]. <br>		<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6H FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [https://pdbe.org/2n6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [https://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [https://pdbe.org/2n6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [https://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:21, 15 March 2023

OCA — Wed, 15 Mar 2023 10:21:46 GMT

←Older revision		Revision as of 10:21, 15 March 2023
Line 1:		Line 1:

	==NMR structure for a 2-stranded parallel beta-sheet==		==NMR structure for a 2-stranded parallel beta-sheet==
-	<StructureSection load='2n6h' size='340' side='right'caption='[[2n6h~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='2n6h' size='340' side='right'caption='[[2n6h]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6H FirstGlance]. <br>		<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6H FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2n4n\|2n4n]], [[2n6i\|2n6i]]</div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [https://pdbe.org/2n6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [https://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [https://pdbe.org/2n6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [https://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cornilescu, G]]	+	[[Category: Cornilescu G]]
-	[[Category: Gellman~~, S H~~]]	+	[[Category: Gellman SH]]
-	[[Category: Kung~~, V M]]~~	+	[[Category: Kung VM]]
-	~~[[Category: De novo protein~~]]	+

OCA at 15:40, 8 June 2021

OCA — Tue, 08 Jun 2021 15:40:52 GMT

←Older revision		Revision as of 15:40, 8 June 2021
Line 3:		Line 3:
	<StructureSection load='2n6h' size='340' side='right'caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2n6h' size='340' side='right'caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2N6H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6H FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n4n\|2n4n]], [[2n6i\|2n6i]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2n4n\|2n4n]], [[2n6i\|2n6i]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [~~http~~://pdbe.org/2n6h PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [https://pdbe.org/2n6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [https://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:13, 21 May 2019

OCA — Tue, 21 May 2019 09:13:56 GMT

←Older revision		Revision as of 09:13, 21 May 2019
Line 1:		Line 1:

	==NMR structure for a 2-stranded parallel beta-sheet==		==NMR structure for a 2-stranded parallel beta-sheet==
-	<StructureSection load='2n6h' size='340' side='right' caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='2n6h' size='340' side='right'caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N6H FirstGlance]. <br>		<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N6H FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Cornilescu, G]]		[[Category: Cornilescu, G]]
	[[Category: Gellman, S H]]		[[Category: Gellman, S H]]
	[[Category: Kung, V M]]		[[Category: Kung, V M]]
	[[Category: De novo protein]]		[[Category: De novo protein]]

OCA at 17:13, 18 August 2017

OCA — Fri, 18 Aug 2017 17:13:29 GMT

←Older revision		Revision as of 17:13, 18 August 2017
Line 1:		Line 1:
		+
	==NMR structure for a 2-stranded parallel beta-sheet==		==NMR structure for a 2-stranded parallel beta-sheet==
	<StructureSection load='2n6h' size='340' side='right' caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2n6h' size='340' side='right' caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n4n\|2n4n]], [[2n6i\|2n6i]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n4n\|2n4n]], [[2n6i\|2n6i]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [http://pdbe.org/2n6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [http://www.ebi.ac.uk/pdbsum/2n6h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [http://pdbe.org/2n6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [http://www.ebi.ac.uk/pdbsum/2n6h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6h ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:31, 27 January 2016

OCA — Wed, 27 Jan 2016 18:31:35 GMT

←Older revision		Revision as of 18:31, 27 January 2016
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==NMR structure for a 2-stranded parallel beta-sheet==
		+	<StructureSection load='2n6h' size='340' side='right' caption='[[2n6h]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2n6h]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N6H FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4G6:2-METHYLPROPANE-1,2-DIAMINE'>4G6</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DPR:D-PROLINE'>DPR</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n4n\|2n4n]], [[2n6i\|2n6i]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6h OCA], [http://pdbe.org/2n6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n6h RCSB], [http://www.ebi.ac.uk/pdbsum/2n6h PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have examined whether parallel beta-sheet secondary structure becomes more stable as the number of beta-strands increases, via comparisons among peptides designed to adopt two- or three-stranded parallel beta-sheet conformations in aqueous solution. Our three-strand design is the first experimental model of a triple-stranded parallel beta-sheet. Analysis of the designed peptides by nuclear magnetic resonance (NMR) and circular dichroism (CD) spectroscopy supports the hypothesis that increasing the number of beta-strands, from two to three, increases the stability of the parallel beta-sheet. We present the first experimental evidence for cooperativity in the folding of a triple-stranded parallel beta-sheet, and we show how minimal model systems may enable experimental documentation of characteristic properties, such as CD spectra, of parallel beta-sheets.

-	~~The entry 2n6h is ON HOLD until Paper Publication~~	+	Impact of Strand Number on Parallel beta-Sheet Stability.,Kung VM, Cornilescu G, Gellman SH Angew Chem Int Ed Engl. 2015 Nov 23;54(48):14336-9. doi: 10.1002/anie.201506448. , Epub 2015 Oct 12. PMID:26457984<ref>PMID:26457984</ref>

-	~~Authors: Kung~~, V.~~M., Cornilescu, G., Gellman,~~ S.H.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: NMR structure for a 2~~-~~stranded parallel beta~~-~~sheet~~	+	<div class="pdbe-citations 2n6h" style="background-color:#fffaf0;"></div>
-	~~[[Category: Unreleased Structures]]~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cornilescu, G]]		[[Category: Cornilescu, G]]
-	[[Category: Kung, V.M]]	+	[[Category: Gellman, S H]]
-	[[Category: ~~Gellman, S.H~~]]	+	[[Category: Kung, V M]]
		+	[[Category: De novo protein]]

OCA at 00:02, 22 October 2015

OCA — Thu, 22 Oct 2015 00:02:23 GMT

←Older revision		Revision as of 00:02, 22 October 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2n6h is ON HOLD	+	The entry 2n6h is ON HOLD until Paper Publication

	Authors: Kung, V.M., Cornilescu, G., Gellman, S.H.		Authors: Kung, V.M., Cornilescu, G., Gellman, S.H.

OCA at 08:01, 7 October 2015

OCA — Wed, 07 Oct 2015 08:01:24 GMT

←Older revision		Revision as of 08:01, 7 October 2015
Line 3:		Line 3:
	The entry 2n6h is ON HOLD		The entry 2n6h is ON HOLD

-	Authors: Kung, V.M., Cornilescu, G.	+	Authors: Kung, V.M., Cornilescu, G., Gellman, S.H.

	Description: NMR structure for a 2-stranded parallel beta-sheet		Description: NMR structure for a 2-stranded parallel beta-sheet
Line 9:		Line 9:
	[[Category: Cornilescu, G]]		[[Category: Cornilescu, G]]
	[[Category: Kung, V.M]]		[[Category: Kung, V.M]]
		+	[[Category: Gellman, S.H]]

OCA: Protected "2n6h" [edit=sysop:move=sysop]

OCA — Wed, 26 Aug 2015 08:03:07 GMT

Protected "2n6h" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:03, 26 August 2015

OCA: New page: '''Unreleased structure''' The entry 2n6h is ON HOLD Authors: Kung, V.M., Cornilescu, G. Description: NMR structure for a 2-stranded parallel beta-sheet [[Category: Unreleased Structur...

OCA — Wed, 26 Aug 2015 08:03:05 GMT

New page: '''Unreleased structure''' The entry 2n6h is ON HOLD Authors: Kung, V.M., Cornilescu, G. Description: NMR structure for a 2-stranded parallel beta-sheet [[Category: Unreleased Structur...

New page

'''Unreleased structure'''

The entry 2n6h is ON HOLD

Authors: Kung, V.M., Cornilescu, G.

Description: NMR structure for a 2-stranded parallel beta-sheet
[[Category: Unreleased Structures]]
[[Category: Cornilescu, G]]
[[Category: Kung, V.M]]