2n6p - Revision history

OCA at 10:21, 15 March 2023

OCA — Wed, 15 Mar 2023 10:21:53 GMT

←Older revision		Revision as of 10:21, 15 March 2023
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	==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==		==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==
-	<StructureSection load='2n6p' size='340' side='right'caption='[[2n6p~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2n6p' size='340' side='right'caption='[[2n6p]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pseae Pseae~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6P FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2n6l\|2n6l]]</div></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [https://pdbe.org/2n6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [https://www.ebi.ac.uk/pdbsum/2n6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6p ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">879793, oprG, PA4067 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [https://pdbe.org/2n6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [https://www.ebi.ac.uk/pdbsum/2n6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6p ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9HWW1_PSEAE Q9HWW1_PSEAE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pseae~~]]	+	[[Category: Pseudomonas aeruginosa PAO1]]
-	[[Category: Edrington~~, T C~~]]	+	[[Category: Edrington TC]]
-	[[Category: Kucharska, I]]	+	[[Category: Kucharska I]]
-	[[Category: Liang, B]]	+	[[Category: Liang B]]
-	[[Category: Seelheim, P]]	+	[[Category: Seelheim P]]
-	[[Category: Tamm~~, L K]]~~	+	[[Category: Tamm LK]]
-	~~[[Category: Membrane protein~~]]	+

OCA at 15:40, 8 June 2021

OCA — Tue, 08 Jun 2021 15:40:57 GMT

←Older revision		Revision as of 15:40, 8 June 2021
Line 1:		Line 1:

	==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==		==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==
-	<StructureSection load='2n6p' size='340' side='right' caption='[[2n6p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2n6p' size='340' side='right'caption='[[2n6p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pseae Pseae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2N6P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseae Pseae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6P FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n6l\|2n6l]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2n6l\|2n6l]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">879793, oprG, PA4067 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">879793, oprG, PA4067 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [~~http~~://pdbe.org/2n6p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2n6p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [https://pdbe.org/2n6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [https://www.ebi.ac.uk/pdbsum/2n6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6p ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pseae]]		[[Category: Pseae]]
	[[Category: Edrington, T C]]		[[Category: Edrington, T C]]

OCA at 17:05, 15 August 2018

OCA — Wed, 15 Aug 2018 17:05:59 GMT

←Older revision		Revision as of 17:05, 15 August 2018
Line 1:		Line 1:
		+
	==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==		==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==
	<StructureSection load='2n6p' size='340' side='right' caption='[[2n6p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2n6p' size='340' side='right' caption='[[2n6p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N6P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N6P FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n6l\|2n6l]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n6l\|2n6l]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [http://pdbe.org/2n6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [http://www.ebi.ac.uk/pdbsum/2n6p PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">879793, oprG, PA4067 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [http://pdbe.org/2n6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [http://www.ebi.ac.uk/pdbsum/2n6p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6p ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Pseae]]
	[[Category: Edrington, T C]]		[[Category: Edrington, T C]]
	[[Category: Kucharska, I]]		[[Category: Kucharska, I]]

OCA at 19:33, 30 December 2015

OCA — Wed, 30 Dec 2015 19:33:01 GMT

←Older revision		Revision as of 19:33, 30 December 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa==
		+	<StructureSection load='2n6p' size='340' side='right' caption='[[2n6p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2n6p]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N6P FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2n6l\|2n6l]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6p OCA], [http://pdbe.org/2n6p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n6p RCSB], [http://www.ebi.ac.uk/pdbsum/2n6p PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	OprG is an outer membrane protein of Pseudomonas aeruginosa whose function as an antibiotic-sensitive porin has been controversial and not well defined. Circumstantial evidence led to the proposal that OprG might transport hydrophobic compounds by using a lateral gate in the barrel wall thought to be lined by three conserved prolines. To test this hypothesis and to find the physiological substrates of OprG, we reconstituted the purified protein into liposomes and found it to facilitate the transport of small amino acids such as glycine, alanine, valine, and serine, which was confirmed by Pseudomonas growth assays. The structures of wild-type and a critical proline mutant were determined by nuclear magnetic resonance in dihexanoyl-phosphatidylcholine micellar solutions. Both proteins formed eight-stranded beta-barrels with flexible extracellular loops. The interfacial prolines did not form a lateral gate in these structures, but loop 3 exhibited restricted motions in the inactive P92A mutant but not in wild-type OprG.

-	~~The entry 2n6p is ON HOLD until Paper Publication~~	+	OprG Harnesses the Dynamics of its Extracellular Loops to Transport Small Amino Acids across the Outer Membrane of Pseudomonas aeruginosa.,Kucharska I, Seelheim P, Edrington T, Liang B, Tamm LK Structure. 2015 Dec 1;23(12):2234-45. doi: 10.1016/j.str.2015.10.009. Epub 2015, Nov 19. PMID:26655471<ref>PMID:26655471</ref>

-	~~Authors: Kucharska~~, I.~~, Seelheim, P~~.~~, Edrington, T.C., Liang, B., Tamm, L.K~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa~~	+	<div class="pdbe-citations 2n6p" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Edrington, T C]]
	[[Category: Kucharska, I]]		[[Category: Kucharska, I]]
-	[[Category: ~~Edrington~~, ~~T.C~~]]	+	[[Category: Liang, B]]
	[[Category: Seelheim, P]]		[[Category: Seelheim, P]]
-	[[Category: ~~Liang~~, B]]	+	[[Category: Tamm, L K]]
-	[[Category: ~~Tamm, L.K~~]]	+	[[Category: Membrane protein]]

OCA at 22:31, 30 November 2015

OCA — Mon, 30 Nov 2015 22:31:18 GMT

←Older revision		Revision as of 22:31, 30 November 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2n6p is ON HOLD	+	The entry 2n6p is ON HOLD until Paper Publication

	Authors: Kucharska, I., Seelheim, P., Edrington, T.C., Liang, B., Tamm, L.K.		Authors: Kucharska, I., Seelheim, P., Edrington, T.C., Liang, B., Tamm, L.K.

OCA: Protected "2n6p" [edit=sysop:move=sysop]

OCA — Wed, 02 Sep 2015 06:59:05 GMT

Protected "2n6p" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:59, 2 September 2015

OCA: New page: '''Unreleased structure''' The entry 2n6p is ON HOLD Authors: Kucharska, I., Seelheim, P., Edrington, T.C., Liang, B., Tamm, L.K. Description: Solution NMR structure of Outer Membrane ...

OCA — Wed, 02 Sep 2015 06:59:04 GMT

New page: '''Unreleased structure''' The entry 2n6p is ON HOLD Authors: Kucharska, I., Seelheim, P., Edrington, T.C., Liang, B., Tamm, L.K. Description: Solution NMR structure of Outer Membrane ...

New page

'''Unreleased structure'''

The entry 2n6p is ON HOLD

Authors: Kucharska, I., Seelheim, P., Edrington, T.C., Liang, B., Tamm, L.K.

Description: Solution NMR structure of Outer Membrane Protein G P92A mutant from Pseudomonas aeruginosa
[[Category: Unreleased Structures]]
[[Category: Kucharska, I]]
[[Category: Edrington, T.C]]
[[Category: Seelheim, P]]
[[Category: Liang, B]]
[[Category: Tamm, L.K]]