2ogw - Revision history

OCA at 00:18, 28 December 2023

OCA — Thu, 28 Dec 2023 00:18:40 GMT

←Older revision		Revision as of 00:18, 28 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGW FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.83Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [https://pdbe.org/2ogw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [https://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [https://pdbe.org/2ogw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [https://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.	+	[https://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI] Involved in the high-affinity zinc uptake transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 38:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Sharma, A]]	+	[[Category: Sharma A]]
-	[[Category: Yogavel, M]]	+	[[Category: Yogavel M]]
-	~~[[Category: Abc]]~~	+
-	~~[[Category: Transport protein]]~~	+
-	~~[[Category: Transporter]]~~	+
-	~~[[Category: Zinc~~]]	+

OCA at 07:51, 2 March 2022

OCA — Wed, 02 Mar 2022 07:51:30 GMT

←Older revision		Revision as of 07:51, 2 March 2022
Line 3:		Line 3:
	<StructureSection load='2ogw' size='340' side='right'caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='2ogw' size='340' side='right'caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2OGW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OGW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [~~http~~://pdbe.org/2ogw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [https://pdbe.org/2ogw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [https://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.	+	[[https://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:01, 27 May 2020

OCA — Wed, 27 May 2020 08:01:05 GMT

←Older revision		Revision as of 08:01, 27 May 2020
Line 1:		Line 1:

	==Structure of ABC type zinc transporter from E. coli==		==Structure of ABC type zinc transporter from E. coli==
-	<StructureSection load='2ogw' size='340' side='right' caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>	+	<StructureSection load='2ogw' size='340' side='right'caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2OGW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2OGW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://pdbe.org/2ogw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://pdbe.org/2ogw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[ABC transporter\|ABC transporter]]	+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
	[[Category: Sharma, A]]		[[Category: Sharma, A]]
	[[Category: Yogavel, M]]		[[Category: Yogavel, M]]

OCA at 07:14, 22 August 2018

OCA — Wed, 22 Aug 2018 07:14:56 GMT

←Older revision		Revision as of 07:14, 22 August 2018
Line 1:		Line 1:
		+
	==Structure of ABC type zinc transporter from E. coli==		==Structure of ABC type zinc transporter from E. coli==
	<StructureSection load='2ogw' size='340' side='right' caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='2ogw' size='340' side='right' caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://pdbe.org/2ogw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://pdbe.org/2ogw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ogw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ogw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 41:		Line 42:
	[[Category: Transport protein]]		[[Category: Transport protein]]
	[[Category: Transporter]]		[[Category: Transporter]]
		+	[[Category: Zinc]]

OCA at 10:50, 11 September 2015

OCA — Fri, 11 Sep 2015 10:50:11 GMT

←Older revision		Revision as of 10:50, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://pdbe.org/2ogw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ogw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 15:27, 25 December 2014

OCA — Thu, 25 Dec 2014 15:27:03 GMT

←Older revision		Revision as of 15:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OGW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OGW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Sharma, A.]]	+	[[Category: Sharma, A]]
-	[[Category: Yogavel, M.]]	+	[[Category: Yogavel, M]]
	[[Category: Abc]]		[[Category: Abc]]
	[[Category: Transport protein]]		[[Category: Transport protein]]
	[[Category: Transporter]]		[[Category: Transporter]]

OCA at 06:54, 29 September 2014

OCA — Mon, 29 Sep 2014 06:54:53 GMT

←Older revision		Revision as of 06:54, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2ogw.~~png~~\|~~left~~\|200px]]	+	==Structure of ABC type zinc transporter from E. coli==
		+	<StructureSection load='2ogw' size='340' side='right' caption='[[2ogw]], [[Resolution\|resolution]] 1.83Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ogw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OGW FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ogw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ogw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ogw RCSB], [http://www.ebi.ac.uk/pdbsum/2ogw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/2ogw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ATP-binding cassette superfamily of periplasmic metal transporters are known to be vital for maintaining ion homeostasis in several pathogenic and non-pathogenic bacteria. We have determined crystal structure of the high-affinity zinc transporter ZnuA from Escherichia coli at 1.8 A resolution. This structure represents the first native (non-recombinant) protein structure of a periplasmic metal binding protein. ZnuA reveals numerous conformational features, which occur either in Zn(2+) or in Mn(2+) transporters, and presents a unique conformational state. A comprehensive comparison of ZnuA with other periplasmic ligand binding protein structures suggests vital mechanistic differences between bound and release states of metal transporters. The key new attributes in ZnuA include a C-domain disulfide bond, an extra alpha-helix proximal to the highly charged metal chelating mobile loop region, alternate conformations of secondary shell stabilizing residues at the metal binding site, and domain movements potentially controlled by salt bridges. Based on in-depth structural analyses of five metal binding transporters, we present here a mechanistic model termed as "partial domain slippage" for binding and release of Zn(2+).

-	~~{{STRUCTURE_2ogw\| PDB=2ogw \| SCENE= }}~~	+	Structural analysis of ABC-family periplasmic zinc binding protein provides new insights into mechanism of ligand uptake and release.,Chandra BR, Yogavel M, Sharma A J Mol Biol. 2007 Apr 6;367(4):970-82. Epub 2007 Jan 23. PMID:17306297<ref>PMID:17306297</ref>

-	~~===Structure~~ of ~~ABC type zinc transporter from E~~. ~~coli===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17306297}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2ogw]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA].~~	+

	==See Also==		==See Also==
	*[[ABC transporter\|ABC transporter]]		*[[ABC transporter\|ABC transporter]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017306297<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Sharma, A.]]		[[Category: Sharma, A.]]

OCA at 18:19, 20 October 2012

OCA — Sat, 20 Oct 2012 18:19:02 GMT

←Older revision		Revision as of 18:19, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2ogw]] is a 2 chain structure ~~of [[ABC transporter]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA].	+	[[2ogw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OGW OCA].

	==See Also==		==See Also==

OCA at 03:43, 27 July 2012

OCA — Fri, 27 Jul 2012 03:43:23 GMT

←Older revision		Revision as of 03:43, 27 July 2012
Line 1:		Line 1:
	[[Image:2ogw.png\|left\|200px]]		[[Image:2ogw.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2ogw", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2ogw\| PDB=2ogw \| SCENE= }}		{{STRUCTURE_2ogw\| PDB=2ogw \| SCENE= }}

	===Structure of ABC type zinc transporter from E. coli===		===Structure of ABC type zinc transporter from E. coli===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17306297}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17306297 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17306297}}		{{ABSTRACT_PUBMED_17306297}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[ABC transporter]]	+	*[[ABC transporter\|ABC transporter]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17306297~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017306297</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Sharma, A.]]		[[Category: Sharma, A.]]
Line 32:		Line 21:
	[[Category: Transport protein]]		[[Category: Transport protein]]
	[[Category: Transporter]]		[[Category: Transporter]]
-	[[Category: Zinc]]

OCA: Protected "2ogw" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 09:00:21 GMT

Protected "2ogw" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:00, 26 December 2010