2olq - Revision history

OCA at 10:42, 30 August 2023

OCA — Wed, 30 Aug 2023 10:42:27 GMT

←Older revision		Revision as of 10:42, 30 August 2023
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	<StructureSection load='2olq' size='340' side='right'caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2olq' size='340' side='right'caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OLQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OLQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.94Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP) Phosphoenolpyruvate carboxykinase (ATP)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.49 4.1.1.49] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [https://pdbe.org/2olq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [https://www.ebi.ac.uk/pdbsum/2olq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2olq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [https://pdbe.org/2olq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [https://www.ebi.ac.uk/pdbsum/2olq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2olq ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PCKA_ECOLI PCKA_ECOLI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cotelesage~~, J J~~]]	+	[[Category: Cotelesage JJ]]
-	[[Category: Delbaere~~, L T~~]]	+	[[Category: Delbaere LT]]
-	[[Category: Goldie, H]]	+	[[Category: Goldie H]]
-	[[Category: Novakovski, B]]	+	[[Category: Novakovski B]]
-	[[Category: Puttick, J]]	+	[[Category: Puttick J]]
-	[[Category: Rajabi, B]]	+	[[Category: Rajabi B]]
-	~~[[Category: Co2]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Phosphoenolpyruvate carboxykinase~~]]	+

OCA at 12:59, 9 June 2021

OCA — Wed, 09 Jun 2021 12:59:46 GMT

←Older revision

Revision as of 12:59, 9 June 2021

OCA at 09:03, 18 October 2017

OCA — Wed, 18 Oct 2017 09:03:19 GMT

←Older revision		Revision as of 09:03, 18 October 2017
Line 1:		Line 1:
		+
	==How Does an Enzyme Recognize CO2?==		==How Does an Enzyme Recognize CO2?==
	<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP) Phosphoenolpyruvate carboxykinase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.49 4.1.1.49] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP) Phosphoenolpyruvate carboxykinase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.49 4.1.1.49] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://pdbe.org/2olq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://pdbe.org/2olq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2olq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</div>		</div>
	<div class="pdbe-citations 2olq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2olq" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Phosphoenolpyruvate carboxykinase\|Phosphoenolpyruvate carboxykinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 18:06, 8 February 2016

OCA — Mon, 08 Feb 2016 18:06:08 GMT

←Older revision		Revision as of 18:06, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2olq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:05, 10 September 2015

OCA — Thu, 10 Sep 2015 14:05:31 GMT

←Older revision		Revision as of 14:05, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia coli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OLQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OLQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~562 Escherichia coli~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP) Phosphoenolpyruvate carboxykinase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.49 4.1.1.49] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP) Phosphoenolpyruvate carboxykinase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.49 4.1.1.49] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://pdbe.org/2olq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2olq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli~~]]	+	[[Category: Ecoli]]
	[[Category: Cotelesage, J J]]		[[Category: Cotelesage, J J]]
	[[Category: Delbaere, L T]]		[[Category: Delbaere, L T]]

OCA at 15:05, 19 January 2015

OCA — Mon, 19 Jan 2015 15:05:33 GMT

←Older revision		Revision as of 15:05, 19 January 2015
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Cotelesage, J J.]]	+	[[Category: Cotelesage, J J]]
-	[[Category: Delbaere, L T.]]	+	[[Category: Delbaere, L T]]
-	[[Category: Goldie, H.]]	+	[[Category: Goldie, H]]
-	[[Category: Novakovski, B.]]	+	[[Category: Novakovski, B]]
-	[[Category: Puttick, J.]]	+	[[Category: Puttick, J]]
-	[[Category: Rajabi, B.]]	+	[[Category: Rajabi, B]]
	[[Category: Co2]]		[[Category: Co2]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Phosphoenolpyruvate carboxykinase]]		[[Category: Phosphoenolpyruvate carboxykinase]]

OCA at 06:28, 10 October 2014

OCA — Fri, 10 Oct 2014 06:28:26 GMT

←Older revision		Revision as of 06:28, 10 October 2014
Line 2:		Line 2:
	<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. <br>	+	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OLQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.~~2 2~~.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(ATP) Phosphoenolpyruvate carboxykinase (ATP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.49 4.1.1.49] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	How does an enzyme recognize CO2?,Cotelesage JJ, Puttick J, Goldie H, Rajabi B, Novakovski B, Delbaere LT Int J Biochem Cell Biol. 2007;39(6):1204-10. Epub 2007 Mar 30. PMID:17475535<ref>PMID:17475535</ref>		How does an enzyme recognize CO2?,Cotelesage JJ, Puttick J, Goldie H, Rajabi B, Novakovski B, Delbaere LT Int J Biochem Cell Biol. 2007;39(6):1204-10. Epub 2007 Mar 30. PMID:17475535<ref>PMID:17475535</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Phosphoenolpyruvate carboxykinase\|Phosphoenolpyruvate carboxykinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:37, 7 May 2014

OCA — Wed, 07 May 2014 08:37:25 GMT

←Older revision		Revision as of 08:37, 7 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2olq.~~png~~\|~~left~~\|200px]]	+	==How Does an Enzyme Recognize CO2?==
		+	<StructureSection load='2olq' size='340' side='right' caption='[[2olq]], [[Resolution\|resolution]] 1.94Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2olq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pckA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2olq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2olq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2olq RCSB], [http://www.ebi.ac.uk/pdbsum/2olq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ol/2olq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Phosphoenolpyruvate carboxykinase (PCK) reversibly catalyzes the carboxylation of phosphoenolpyruvate to oxaloacetate. Carbon dioxide, and not bicarbonate ion, is the substrate utilized. Assays of the carboxylation reaction show that initial velocities are 7.6-fold higher when CO(2) is used instead of HCO(3)(-). Two Escherichia coli PCK-CO(2) crystal structures are presented here. The location of CO(2) is the same for both structures; however the orientation of CO(2) is significantly different, likely from the presence of a manganese ion in one of the structures. PCK and the other three known protein-CO(2) crystal structure complexes have been compared; all have CO(2) hydrogen bonding with a basic amino acid side chain (Arg65 or Lys213 in PCK), likely to polarize CO(2) to make the central carbon atom more electrophilic and thus more reactive. Kinetic studies found that the PCK mutant Arg65Gln increased the K(M) for substrates PEP and oxaloacetate but not for CO(2). The unchanged K(M) for CO(2) can be explained since the Arg65Gln mutant likely maintains a hydrogen bond to one of the oxygen atoms of carbon dioxide.

-	~~<!--~~	+	How does an enzyme recognize CO2?,Cotelesage JJ, Puttick J, Goldie H, Rajabi B, Novakovski B, Delbaere LT Int J Biochem Cell Biol. 2007;39(6):1204-10. Epub 2007 Mar 30. PMID:17475535<ref>PMID:17475535</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2olq"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_2olq\| PDB=2olq \| SCENE= }}~~	+

-	~~===How Does an Enzyme Recognize CO2?===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_17475535}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 17475535 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_17475535}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2olq]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017475535<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Cotelesage, J J.]]		[[Category: Cotelesage, J J.]]

OCA: Protected "2olq" [edit=sysop:move=sysop]

OCA — Wed, 16 Nov 2011 10:01:52 GMT

Protected "2olq" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:01, 16 November 2011

OCA at 10:01, 16 November 2011

OCA — Wed, 16 Nov 2011 10:01:51 GMT

←Older revision		Revision as of 10:01, 16 November 2011
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-	{{Seed}}
	[[Image:2olq.png\|left\|200px]]		[[Image:2olq.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2OLQ~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA].	+	[[2olq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OLQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17475535~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017475535</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Cotelesage, J J.]]		[[Category: Cotelesage, J J.]]
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	[[Category: Rajabi, B.]]		[[Category: Rajabi, B.]]
	[[Category: Co2]]		[[Category: Co2]]
		+	[[Category: Lyase]]
	[[Category: Phosphoenolpyruvate carboxykinase]]		[[Category: Phosphoenolpyruvate carboxykinase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 01:00:04 2009''