2p3x - Revision history

OCA at 10:53, 30 August 2023

OCA — Wed, 30 Aug 2023 10:53:52 GMT

←Older revision		Revision as of 10:53, 30 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3X FirstGlance]. <br>		<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3X FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=C2O:CU~~-~~O-CU+LINKAGE'>C2O</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [https://pdbe.org/2p3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [https://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [https://pdbe.org/2p3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [https://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PPO_VITVI PPO_VITVI]] Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.	+	[https://www.uniprot.org/uniprot/PPO_VITVI PPO_VITVI] Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Catechol oxidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Vitis vinifera]]		[[Category: Vitis vinifera]]
-	[[Category: Blanco-Labra, A]]	+	[[Category: Blanco-Labra A]]
-	~~[[Category: Grajeda, J P.Reyes~~]]	+	[[Category: Mendiola-Olaya E]]
-	[[Category: Mendiola-Olaya, E]]	+	[[Category: Moreno A]]
-	[[Category: Moreno, A]]	+	[[Category: Reyes Grajeda JP]]
-	[[Category: ~~Smith, G M~~]]	+	[[Category: Smith GM]]
-	[[Category: ~~Virador, V M~~]]	+	[[Category: Virador VM]]
-	[[Category: ~~Whitaker, J R~~]]	+	[[Category: Whitaker JR]]
-	[[Category: ~~Grenache grape]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Polyphenol oxidase~~]]	+

OCA at 07:54, 2 March 2022

OCA — Wed, 02 Mar 2022 07:54:06 GMT

←Older revision		Revision as of 07:54, 2 March 2022
Line 3:		Line 3:
	<StructureSection load='2p3x' size='340' side='right'caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2p3x' size='340' side='right'caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2P3X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P3X FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [~~http~~://pdbe.org/2p3x PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [https://pdbe.org/2p3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [https://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PPO_VITVI PPO_VITVI]] Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.	+	[[https://www.uniprot.org/uniprot/PPO_VITVI PPO_VITVI]] Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2p3x" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2p3x" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Tyrosinase 3D structures\|Tyrosinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:07, 27 May 2020

OCA — Wed, 27 May 2020 08:07:09 GMT

←Older revision		Revision as of 08:07, 27 May 2020
Line 1:		Line 1:

	==Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase==		==Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase==
-	<StructureSection load='2p3x' size='340' side='right' caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='2p3x' size='340' side='right'caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2P3X FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2P3X FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://pdbe.org/2p3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://pdbe.org/2p3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Catechol oxidase]]		[[Category: Catechol oxidase]]
		+	[[Category: Large Structures]]
	[[Category: Vitis vinifera]]		[[Category: Vitis vinifera]]
	[[Category: Blanco-Labra, A]]		[[Category: Blanco-Labra, A]]

OCA at 07:22, 22 August 2018

OCA — Wed, 22 Aug 2018 07:22:33 GMT

←Older revision		Revision as of 07:22, 22 August 2018
Line 1:		Line 1:
		+
	==Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase==		==Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase==
	<StructureSection load='2p3x' size='340' side='right' caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2p3x' size='340' side='right' caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://pdbe.org/2p3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://pdbe.org/2p3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2p3x ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3x_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3x_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:15, 10 February 2016

OCA — Wed, 10 Feb 2016 05:15:39 GMT

←Older revision		Revision as of 05:15, 10 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p3x ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:44, 11 September 2015

OCA — Fri, 11 Sep 2015 05:44:10 GMT

←Older revision		Revision as of 05:44, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://pdbe.org/2p3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2p3x" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:04, 25 December 2014

OCA — Thu, 25 Dec 2014 12:04:23 GMT

←Older revision		Revision as of 12:04, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P3X FirstGlance]. <br>		<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P3X FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PPO_VITVI PPO_VITVI]] Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	[[Category: Catechol oxidase]]		[[Category: Catechol oxidase]]
	[[Category: Vitis vinifera]]		[[Category: Vitis vinifera]]
-	[[Category: Blanco-Labra, A.]]	+	[[Category: Blanco-Labra, A]]
-	[[Category: Grajeda, J P.Reyes.]]	+	[[Category: Grajeda, J P.Reyes]]
-	[[Category: Mendiola-Olaya, E.]]	+	[[Category: Mendiola-Olaya, E]]
-	[[Category: Moreno, A.]]	+	[[Category: Moreno, A]]
-	[[Category: Smith, G M.]]	+	[[Category: Smith, G M]]
-	[[Category: Virador, V M.]]	+	[[Category: Virador, V M]]
-	[[Category: Whitaker, J R.]]	+	[[Category: Whitaker, J R]]
	[[Category: Grenache grape]]		[[Category: Grenache grape]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Polyphenol oxidase]]		[[Category: Polyphenol oxidase]]

OCA at 18:58, 30 September 2014

OCA — Tue, 30 Sep 2014 18:58:59 GMT

←Older revision		Revision as of 18:58, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2p3x.~~png\|left~~\|200px]]	+	==Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase==
		+	<StructureSection load='2p3x' size='340' side='right' caption='[[2p3x]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2P3X FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2O:CU-O-CU+LINKAGE'>C2O</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_oxidase Catechol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.3.1 1.10.3.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p3x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2p3x RCSB], [http://www.ebi.ac.uk/pdbsum/2p3x PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p3/2p3x_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The full-length cDNA sequence (P93622_VITVI) of polyphenol oxidase (PPO) cDNA from grape Vitis vinifera L., cv Grenache, was found to encode a translated protein of 607 amino acids with an expected molecular weight of ca. 67 kDa and a predicted pI of 6.83. The translated amino acid sequence was 99%, identical to that of a white grape berry PPO (1) (5 out of 607 amino acid potential sequence differences). The protein was purified from Grenache grape berries by using traditional methods, and it was crystallized with ammonium acetate by the hanging-drop vapor diffusion method. The crystals were orthorhombic, space group C222(1). The structure was obtained at 2.2 A resolution using synchrotron radiation using the 39 kDa isozyme of sweet potato PPO (PDB code: 1BT1 ) as a phase donor. The basic symmetry of the cell parameters (a, b, and c and alpha, beta, and gamma) as well as in the number of asymmetric units in the unit cell of the crystals of PPO, differed between the two proteins. The structures of the two enzymes are quite similar in overall fold, the location of the helix bundles at the core, and the active site in which three histidines bind each of the two catalytic copper ions, and one of the histidines is engaged in a thioether linkage with a cysteine residue. The possibility that the formation of the Cys-His thioether linkage constitutes the activation step is proposed. No evidence of phosphorylation or glycoslyation was found in the electron density map. The mass of the crystallized protein appears to be only 38.4 kDa, and the processing that occurs in the grape berry that leads to this smaller size is discussed.

-	~~{{STRUCTURE_2p3x\| PDB=2p3x \| SCENE= }}~~	+	Cloning, sequencing, purification, and crystal structure of Grenache (Vitis vinifera) polyphenol oxidase.,Virador VM, Reyes Grajeda JP, Blanco-Labra A, Mendiola-Olaya E, Smith GM, Moreno A, Whitaker JR J Agric Food Chem. 2010 Jan 27;58(2):1189-201. PMID:20039636<ref>PMID:20039636</ref>

-	~~===Crystal structure~~ of ~~Grenache (Vitis vinifera) Polyphenol Oxidase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20039636}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2p3x]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Vitis_vinifera Vitis vinifera]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020039636<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Catechol oxidase]]		[[Category: Catechol oxidase]]
	[[Category: Vitis vinifera]]		[[Category: Vitis vinifera]]

OCA: Protected "2p3x" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 11:17:54 GMT

Protected "2p3x" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:17, 7 January 2013

OCA at 11:17, 7 January 2013

OCA — Mon, 07 Jan 2013 11:17:53 GMT

←Older revision		Revision as of 11:17, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2p3x.png\|left\|200px]]		[[Image:2p3x.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2p3x", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2p3x\| PDB=2p3x \| SCENE= }}		{{STRUCTURE_2p3x\| PDB=2p3x \| SCENE= }}

	===Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase===		===Crystal structure of Grenache (Vitis vinifera) Polyphenol Oxidase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20039636}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20039636 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20039636}}		{{ABSTRACT_PUBMED_20039636}}

	==About this Structure==		==About this Structure==
-	~~2P3X~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA].	+	[[2p3x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P3X OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20039636~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020039636</ref><references group="xtra"/>
	[[Category: Catechol oxidase]]		[[Category: Catechol oxidase]]
	[[Category: Vitis vinifera]]		[[Category: Vitis vinifera]]
Line 36:		Line 24:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Polyphenol oxidase]]		[[Category: Polyphenol oxidase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:04:46 2010''