2pzz - Revision history

OCA at 15:37, 17 June 2021

OCA — Thu, 17 Jun 2021 15:37:24 GMT

←Older revision		Revision as of 15:37, 17 June 2021
Line 1:		Line 1:

	==2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii==		==2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii==
-	<StructureSection load='2pzz' size='340' side='right' caption='[[2pzz]]~~, [[Resolution\|resolution]] 2.20Å~~' scene=''>	+	<StructureSection load='2pzz' size='340' side='right'caption='[[2pzz]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>
-	</td></tr>~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [https://pdbe.org/2pzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [https://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pzz ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>~~	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [~~http~~://pdbe.org/2pzz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pzz ProSAT], [~~http~~://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>	+
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 19:		Line 16:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pzz ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pzz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have determined X-ray crystal structures of four members of an archaeal specific family of proteins of unknown function (UPF0201; Pfam classification: DUF54) to advance our understanding of the genetic repertoire of archaea. Despite low pairwise amino acid sequence identities (10-40%) and the absence of conserved sequence motifs, the three-dimensional structures of these proteins are remarkably similar to one another. Their common polypeptide chain fold, encompassing a five-stranded antiparallel beta-sheet and five alpha-helices, proved to be quite unexpectedly similar to that of the RRM-type RNA-binding domain of the ribosomal L5 protein, which is responsible for binding the 5S- rRNA. Structure-based sequence alignments enabled construction of a phylogenetic tree relating UPF0201 family members to L5 ribosomal proteins and other structurally similar RNA binding proteins, thereby expanding our understanding of the evolutionary purview of the RRM superfamily. Analyses of the surfaces of these newly determined UPF0201 structures suggest that they probably do not function as RNA binding proteins, and that this domain specific family of proteins has acquired a novel function in archaebacteria, which awaits experimental elucidation.
-
-	UPF201 archaeal specific family members reveal structural similarity to RNA-binding proteins but low likelihood for RNA-binding function.,Rao KN, Burley SK, Swaminathan S PLoS ONE. 2008;3(12):e3903. Epub 2008 Dec 11. PMID:19079550<ref>PMID:19079550</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2pzz" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Metja~~]]	+	[[Category: Large Structures]]
-	[[Category: Burley~~, S K]]~~	+	[[Category: Burley SK]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Rao KN]]
-	[[Category: Rao~~, K N~~]]	+	[[Category: Swaminathan S]]
-	[[Category: Swaminathan, S]]	+
-	~~[[Category: Methanococcus jannaschii]]~~	+
-	~~[[Category: Mj1564]]~~	+
-	~~[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Unknown function]]~~	+
-	~~[[Category: Upf0201~~]]	+

OCA at 08:21, 29 August 2018

OCA — Wed, 29 Aug 2018 08:21:47 GMT

←Older revision		Revision as of 08:21, 29 August 2018
Line 1:		Line 1:
		+
	==2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii==		==2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii==
	<StructureSection load='2pzz' size='340' side='right' caption='[[2pzz]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2pzz' size='340' side='right' caption='[[2pzz]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://pdbe.org/2pzz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://pdbe.org/2pzz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pzz ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/2pzz_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/2pzz_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 19:37, 8 February 2016

OCA — Mon, 08 Feb 2016 19:37:54 GMT

←Older revision		Revision as of 19:37, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pzz ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:45, 10 September 2015

OCA — Thu, 10 Sep 2015 14:45:10 GMT

←Older revision		Revision as of 14:45, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2pzz' size='340' side='right' caption='[[2pzz]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2pzz' size='340' side='right' caption='[[2pzz]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 ~~Methanocaldococcus jannaschii DSM 2661~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://pdbe.org/2pzz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2pzz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Methanocaldococcus jannaschii dsm 2661~~]]	+	[[Category: Metja]]
	[[Category: Burley, S K]]		[[Category: Burley, S K]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 12:26, 6 November 2014

OCA — Thu, 06 Nov 2014 12:26:37 GMT

←Older revision		Revision as of 12:26, 6 November 2014
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Methanocaldococcus jannaschii dsm 2661]]		[[Category: Methanocaldococcus jannaschii dsm 2661]]
		+	[[Category: Burley, S K]]
		+	[[Category: Structural genomic]]
		+	[[Category: Rao, K N]]
		+	[[Category: Swaminathan, S]]
	[[Category: Methanococcus jannaschii]]		[[Category: Methanococcus jannaschii]]
	[[Category: Mj1564]]		[[Category: Mj1564]]
		+	[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
		+	[[Category: PSI, Protein structure initiative]]
		+	[[Category: Unknown function]]
	[[Category: Upf0201]]		[[Category: Upf0201]]

OCA at 11:43, 6 November 2014

OCA — Thu, 06 Nov 2014 11:43:07 GMT

←Older revision		Revision as of 11:43, 6 November 2014
Line 33:		Line 33:
	[[Category: Methanococcus jannaschii]]		[[Category: Methanococcus jannaschii]]
	[[Category: Mj1564]]		[[Category: Mj1564]]
-	[[Category: Psi2]]
	[[Category: Upf0201]]		[[Category: Upf0201]]

OCA at 11:25, 6 November 2014

OCA — Thu, 06 Nov 2014 11:25:07 GMT

←Older revision		Revision as of 11:25, 6 November 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 Methanocaldococcus jannaschii DSM 2661])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 Methanocaldococcus jannaschii DSM 2661])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Methanocaldococcus jannaschii dsm 2661]]		[[Category: Methanocaldococcus jannaschii dsm 2661]]
-	[[Category: Burley, S K.]]
-	[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
-	[[Category: Rao, K N.]]
-	[[Category: Swaminathan, S.]]
-	[[Category: 10077a3]]
	[[Category: Methanococcus jannaschii]]		[[Category: Methanococcus jannaschii]]
	[[Category: Mj1564]]		[[Category: Mj1564]]
-	[[Category: New york sgx research center for structural genomic]]
-	[[Category: Nysgxrc]]
-	[[Category: Protein structure initiative]]
	[[Category: Psi2]]		[[Category: Psi2]]
-	[[Category: Structural genomic]]
-	[[Category: Unknown function]]
	[[Category: Upf0201]]		[[Category: Upf0201]]

OCA at 19:15, 30 September 2014

OCA — Tue, 30 Sep 2014 19:15:00 GMT

←Older revision		Revision as of 19:15, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2pzz.~~png~~\|~~left~~\|200px]]	+	==2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii==
		+	<StructureSection load='2pzz' size='340' side='right' caption='[[2pzz]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PZZ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2nwu\|2nwu]], [[2nrq\|2nrq]], [[2ogk\|2ogk]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MJ1564 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 Methanocaldococcus jannaschii DSM 2661])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pzz RCSB], [http://www.ebi.ac.uk/pdbsum/2pzz PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/2pzz TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/2pzz_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined X-ray crystal structures of four members of an archaeal specific family of proteins of unknown function (UPF0201; Pfam classification: DUF54) to advance our understanding of the genetic repertoire of archaea. Despite low pairwise amino acid sequence identities (10-40%) and the absence of conserved sequence motifs, the three-dimensional structures of these proteins are remarkably similar to one another. Their common polypeptide chain fold, encompassing a five-stranded antiparallel beta-sheet and five alpha-helices, proved to be quite unexpectedly similar to that of the RRM-type RNA-binding domain of the ribosomal L5 protein, which is responsible for binding the 5S- rRNA. Structure-based sequence alignments enabled construction of a phylogenetic tree relating UPF0201 family members to L5 ribosomal proteins and other structurally similar RNA binding proteins, thereby expanding our understanding of the evolutionary purview of the RRM superfamily. Analyses of the surfaces of these newly determined UPF0201 structures suggest that they probably do not function as RNA binding proteins, and that this domain specific family of proteins has acquired a novel function in archaebacteria, which awaits experimental elucidation.

-	~~{{STRUCTURE_2pzz\| PDB=2pzz \| SCENE= }}~~	+	UPF201 archaeal specific family members reveal structural similarity to RNA-binding proteins but low likelihood for RNA-binding function.,Rao KN, Burley SK, Swaminathan S PLoS ONE. 2008;3(12):e3903. Epub 2008 Dec 11. PMID:19079550<ref>PMID:19079550</ref>

-	~~===2.2 A resolution crystal structure~~ of ~~UPF0201 protein from Methanococcus jannaschii===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19079550}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2pzz]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019079550<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Methanocaldococcus jannaschii dsm 2661]]		[[Category: Methanocaldococcus jannaschii dsm 2661]]
	[[Category: Burley, S K.]]		[[Category: Burley, S K.]]

OCA: Protected "2pzz" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:57:34 GMT

Protected "2pzz" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:57, 7 January 2013

OCA at 21:57, 7 January 2013

OCA — Mon, 07 Jan 2013 21:57:31 GMT

←Older revision		Revision as of 21:57, 7 January 2013
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-	{{Seed}}
	[[Image:2pzz.png\|left\|200px]]		[[Image:2pzz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2pzz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2pzz\| PDB=2pzz \| SCENE= }}		{{STRUCTURE_2pzz\| PDB=2pzz \| SCENE= }}

	===2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii===		===2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19079550}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19079550 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19079550}}		{{ABSTRACT_PUBMED_19079550}}

	==About this Structure==		==About this Structure==
-	~~2PZZ~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA].	+	[[2pzz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PZZ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19079550~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019079550</ref><references group="xtra"/>
	[[Category: Methanocaldococcus jannaschii dsm 2661]]		[[Category: Methanocaldococcus jannaschii dsm 2661]]
	[[Category: Burley, S K.]]		[[Category: Burley, S K.]]
Line 30:		Line 18:
	[[Category: Swaminathan, S.]]		[[Category: Swaminathan, S.]]
	[[Category: 10077a3]]		[[Category: 10077a3]]
-	[[Category: Crystal structure]]
	[[Category: Methanococcus jannaschii]]		[[Category: Methanococcus jannaschii]]
	[[Category: Mj1564]]		[[Category: Mj1564]]
Line 40:		Line 27:
	[[Category: Unknown function]]		[[Category: Unknown function]]
	[[Category: Upf0201]]		[[Category: Upf0201]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:27:18 2009''