2qgq - Revision history

OCA at 08:19, 25 June 2021

OCA — Fri, 25 Jun 2021 08:19:32 GMT

←Older revision		Revision as of 08:19, 25 June 2021
Line 1:		Line 1:

	==Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77==		==Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77==
-	<StructureSection load='2qgq' size='340' side='right' caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2qgq' size='340' side='right'caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [~~http~~://pdbe.org/2qgq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2qgq ProSAT], [~~http~~://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [https://pdbe.org/2qgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [https://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qgq ProSAT], [https://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RIMO_THEMA RIMO_THEMA]] Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity).	+	[[https://www.uniprot.org/uniprot/RIMO_THEMA RIMO_THEMA]] Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thema]]		[[Category: Thema]]
	[[Category: Acton, T B]]		[[Category: Acton, T B]]

OCA at 18:59, 24 January 2018

OCA — Wed, 24 Jan 2018 18:59:43 GMT

←Older revision		Revision as of 18:59, 24 January 2018
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 43:		Line 43:
	[[Category: Hunt, J F]]		[[Category: Hunt, J F]]
	[[Category: Hussain, M]]		[[Category: Hussain, M]]
-	[[Category: Ma, L-C]]	+	[[Category: Ma, L C]]
	[[Category: Montelione, G T]]		[[Category: Montelione, G T]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

OCA at 09:47, 18 October 2017

OCA — Wed, 18 Oct 2017 09:47:21 GMT

←Older revision		Revision as of 09:47, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77==		==Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77==
	<StructureSection load='2qgq' size='340' side='right' caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2qgq' size='340' side='right' caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://pdbe.org/2qgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://pdbe.org/2qgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qgq ProSAT], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 19:50, 9 February 2016

OCA — Tue, 09 Feb 2016 19:50:14 GMT

←Older revision		Revision as of 19:50, 9 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qgq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:29, 11 September 2015

OCA — Fri, 11 Sep 2015 01:29:34 GMT

←Older revision		Revision as of 01:29, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2qgq' size='340' side='right' caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2qgq' size='340' side='right' caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima_msb8 Thermotoga maritima msb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thema Thema]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 ~~Thermotoga maritima MSB8~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 THEMA])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://pdbe.org/2qgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RIMO_THEMA RIMO_THEMA]] Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2qgq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermotoga maritima msb8~~]]	+	[[Category: Thema]]
	[[Category: Acton, T B]]		[[Category: Acton, T B]]
	[[Category: Chen, C X]]		[[Category: Chen, C X]]

OCA at 09:08, 25 December 2014

OCA — Thu, 25 Dec 2014 09:08:47 GMT

←Older revision		Revision as of 09:08, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 Thermotoga maritima MSB8])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 Thermotoga maritima MSB8])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
-	[[Category: Acton, T B.]]	+	[[Category: Acton, T B]]
-	[[Category: Chen, C X.]]	+	[[Category: Chen, C X]]
-	[[Category: Conover, K.]]	+	[[Category: Conover, K]]
-	[[Category: Cunningham, K.]]	+	[[Category: Cunningham, K]]
-	[[Category: Fang, Y.]]	+	[[Category: Fang, Y]]
-	[[Category: Forouhar, F.]]	+	[[Category: Forouhar, F]]
-	[[Category: Hunt, J F.]]	+	[[Category: Hunt, J F]]
-	[[Category: Hussain, M.]]	+	[[Category: Hussain, M]]
-	[[Category: Ma, L-C.]]	+	[[Category: Ma, L-C]]
-	[[Category: Montelione, G T.]]	+	[[Category: Montelione, G T]]
-	[[Category: ~~NESG, Northeast~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Neely, H.]]	+	[[Category: Neely, H]]
-	[[Category: Seetharaman, J.]]	+	[[Category: Seetharaman, J]]
-	[[Category: Tong, L.]]	+	[[Category: Tong, L]]
-	[[Category: Xiao, R.]]	+	[[Category: Xiao, R]]
	[[Category: Alpha-beta protein]]		[[Category: Alpha-beta protein]]
	[[Category: Nesg]]		[[Category: Nesg]]
-	[[Category: ~~Northeast structural genomics consortium]]~~	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category:~~ Protein structure initiative]]	+
-	~~[[Category: Psi-2]]~~	+
-	~~[[Category: Structural genomic~~]]	+
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 17:57, 30 September 2014

OCA — Tue, 30 Sep 2014 17:57:01 GMT

←Older revision		Revision as of 17:57, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2qgq.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77==
		+	<StructureSection load='2qgq' size='340' side='right' caption='[[2qgq]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2qgq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CXS:3-CYCLOHEXYL-1-PROPYLSULFONIC+ACID'>CXS</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TM_1862 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 Thermotoga maritima MSB8])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgq RCSB], [http://www.ebi.ac.uk/pdbsum/2qgq PDBsum], [http://www.topsan.org/Proteins/NESGC/2qgq TOPSAN]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Post-translational modifications of ribosomal proteins are important for the accuracy of the decoding machinery. A recent in vivo study has shown that the rimO gene is involved in generation of the 3-methylthio derivative of residue Asp-89 in ribosomal protein S12 (Anton, B. P., Saleh, L., Benner, J. S., Raleigh, E. A., Kasif, S., and Roberts, R. J. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 1826-1831). This reaction is formally identical to that catalyzed by MiaB on the C2 of adenosine 37 near the anticodon of several tRNAs. We present spectroscopic evidence that Thermotoga maritima RimO, like MiaB, contains two [4Fe-4S] centers, one presumably bound to three invariant cysteines in the central radical S-adenosylmethionine (AdoMet) domain and the other to three invariant cysteines in the N-terminal UPF0004 domain. We demonstrate that holo-RimO can specifically methylthiolate the aspartate residue of a 20-mer peptide derived from S12, yielding a mixture of mono- and bismethylthio derivatives. Finally, we present the 2.0 A crystal structure of the central radical AdoMet and the C-terminal TRAM (tRNA methyltransferase 2 and MiaB) domains in apo-RimO. Although the core of the open triose-phosphate isomerase (TIM) barrel of the radical AdoMet domain was conserved, RimO showed differences in domain organization compared with other radical AdoMet enzymes. The unusually acidic TRAM domain, likely to bind the basic S12 protein, is located at the distal edge of the radical AdoMet domain. The basic S12 protein substrate is likely to bind RimO through interactions with both the TRAM domain and the concave surface of the incomplete TIM barrel. These biophysical results provide a foundation for understanding the mechanism of methylthioation by radical AdoMet enzymes in the MiaB/RimO family.

-	~~{{STRUCTURE_2qgq\| PDB=2qgq \| SCENE= }}~~	+	Post-translational modification of ribosomal proteins: structural and functional characterization of RimO from Thermotoga maritima, a radical S-adenosylmethionine methylthiotransferase.,Arragain S, Garcia-Serres R, Blondin G, Douki T, Clemancey M, Latour JM, Forouhar F, Neely H, Montelione GT, Hunt JF, Mulliez E, Fontecave M, Atta M J Biol Chem. 2010 Feb 19;285(8):5792-801. Epub 2009 Dec 9. PMID:20007320<ref>PMID:20007320</ref>

-	~~===Crystal structure~~ of ~~TM_1862 from Thermotoga maritima~~. ~~Northeast Structural Genomics Consortium target VR77===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20007320}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2qgq]] is a 8 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020007320<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
	[[Category: Acton, T B.]]		[[Category: Acton, T B.]]

OCA: Protected "2qgq" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 20:35:10 GMT

Protected "2qgq" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:35, 7 January 2013

OCA at 20:35, 7 January 2013

OCA — Mon, 07 Jan 2013 20:35:07 GMT

←Older revision		Revision as of 20:35, 7 January 2013
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-	{{Seed}}
	[[Image:2qgq.png\|left\|200px]]		[[Image:2qgq.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2qgq", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2qgq\| PDB=2qgq \| SCENE= }}		{{STRUCTURE_2qgq\| PDB=2qgq \| SCENE= }}

	===Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77===		===Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20007320}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20007320 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_20007320}}		{{ABSTRACT_PUBMED_20007320}}

	==About this Structure==		==About this Structure==
-	~~2QGQ~~ is a 8 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA].	+	[[2qgq]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20007320~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020007320</ref><references group="xtra"/>
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
	[[Category: Acton, T B.]]		[[Category: Acton, T B.]]
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	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Unknown function]]		[[Category: Unknown function]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 13:11:19 2010''

OCA at 11:11, 3 March 2010

OCA — Wed, 03 Mar 2010 11:11:20 GMT

←Older revision		Revision as of 11:11, 3 March 2010
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	===Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77===		===Crystal structure of TM_1862 from Thermotoga maritima. Northeast Structural Genomics Consortium target VR77===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20007320}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20007320 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20007320}}

	==About this Structure==		==About this Structure==
-	2QGQ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA].	+	2QGQ is a 8 chains structure with sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGQ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20007320</ref><references group="xtra"/>
	[[Category: Thermotoga maritima msb8]]		[[Category: Thermotoga maritima msb8]]
	[[Category: Acton, T B.]]		[[Category: Acton, T B.]]
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	[[Category: Psi-2]]		[[Category: Psi-2]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
		+	[[Category: Unknown function]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Nov 16 14~~:48:~~16 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 13:11:19 2010''