2qvl - Revision history

OCA at 04:07, 2 July 2021

OCA — Fri, 02 Jul 2021 04:07:22 GMT

←Older revision		Revision as of 04:07, 2 July 2021
Line 1:		Line 1:

	==Crystal Structure of Diacylglycerol Kinase==		==Crystal Structure of Diacylglycerol Kinase==
-	<StructureSection load='2qvl' size='340' side='right' caption='[[2qvl]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='2qvl' size='340' side='right'caption='[[2qvl]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2qvl]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2QVL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2qvl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVL FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qv7\|2qv7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qv7\|2qv7]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [~~http~~://pdbe.org/2qvl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2qvl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvl ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [https://pdbe.org/2qvl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [https://www.ebi.ac.uk/pdbsum/2qvl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DAGK_STAAR DAGK_STAAR]] Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.<ref>PMID:17535816</ref>	+	[[https://www.uniprot.org/uniprot/DAGK_STAAR DAGK_STAAR]] Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.<ref>PMID:17535816</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:

	==See Also==		==See Also==
-	*[[Diacylglycerol kinase\|Diacylglycerol kinase]]	+	*[[Diacylglycerol kinase 3D structures\|Diacylglycerol kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 39:		Line 39:
	</StructureSection>		</StructureSection>
	[[Category: Diacylglycerol kinase]]		[[Category: Diacylglycerol kinase]]
		+	[[Category: Large Structures]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Jerga, A]]		[[Category: Jerga, A]]

OCA at 11:05, 5 September 2018

OCA — Wed, 05 Sep 2018 11:05:26 GMT

←Older revision		Revision as of 11:05, 5 September 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Diacylglycerol Kinase==		==Crystal Structure of Diacylglycerol Kinase==
	<StructureSection load='2qvl' size='340' side='right' caption='[[2qvl]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='2qvl' size='340' side='right' caption='[[2qvl]], [[Resolution\|resolution]] 2.40Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://pdbe.org/2qvl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://pdbe.org/2qvl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvl_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvl_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qvl ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:24, 11 September 2015

OCA — Fri, 11 Sep 2015 11:24:32 GMT

←Older revision		Revision as of 11:24, 11 September 2015
Line 7:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://pdbe.org/2qvl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DAGK_STAAR DAGK_STAAR]] Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway.<ref>PMID:17535816</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2qvl" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Diacylglycerol kinase\|Diacylglycerol kinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:25, 19 January 2015

OCA — Mon, 19 Jan 2015 15:25:41 GMT

←Older revision		Revision as of 15:25, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2qvl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2qvl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qv7\|2qv7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qv7\|2qv7]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Diacylglycerol kinase]]		[[Category: Diacylglycerol kinase]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
-	[[Category: Jerga, A.]]	+	[[Category: Jerga, A]]
-	[[Category: Miller, D J.]]	+	[[Category: Miller, D J]]
-	[[Category: Rock, C O.]]	+	[[Category: Rock, C O]]
-	[[Category: White, S W.]]	+	[[Category: White, S W]]
	[[Category: Alpha-beta domain 1]]		[[Category: Alpha-beta domain 1]]
	[[Category: Beta sandwich domain 2]]		[[Category: Beta sandwich domain 2]]
	[[Category: Native protein]]		[[Category: Native protein]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 18:47, 30 September 2014

OCA — Tue, 30 Sep 2014 18:47:02 GMT

←Older revision		Revision as of 18:47, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2qvl.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of Diacylglycerol Kinase==
		+	<StructureSection load='2qvl' size='340' side='right' caption='[[2qvl]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2qvl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QVL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2qv7\|2qv7]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SAR1989 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diacylglycerol_kinase Diacylglycerol kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.107 2.7.1.107] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qvl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qvl RCSB], [http://www.ebi.ac.uk/pdbsum/2qvl PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qv/2qvl_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Soluble diacylglycerol (DAG) kinases function as regulators of diacylglycerol metabolism in cell signaling and intermediary metabolism. We report the structure of a DAG kinase, DgkB from Staphylococcus aureus, both as the free enzyme and in complex with ADP. The molecule is a tight homodimer, and each monomer comprises two domains with the catalytic center located within the interdomain cleft. Two distinctive features of DkgB are a structural Mg2+ site and an associated AspwaterMg2+ network that extends toward the active site locale. Site-directed mutagenesis revealed that these features play important roles in the catalytic mechanism. The key active site residues and the components of the AspwaterMg2+ network are conserved in the catalytic cores of the mammalian signaling DAG kinases, indicating that these enzymes use the same mechanism and have similar structures as DgkB.

-	~~{{STRUCTURE_2qvl\| PDB=2qvl \| SCENE= }}~~	+	Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases.,Miller DJ, Jerga A, Rock CO, White SW Structure. 2008 Jul;16(7):1036-46. PMID:18611377<ref>PMID:18611377</ref>

-	~~===Crystal Structure~~ of ~~Diacylglycerol Kinase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18611377}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2qvl]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Staphylococcus_aureus Staphylococcus aureus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018611377<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Diacylglycerol kinase]]		[[Category: Diacylglycerol kinase]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]

OCA: Protected "2qvl" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 18:44:29 GMT

Protected "2qvl" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:44, 7 January 2013

OCA at 18:44, 7 January 2013

OCA — Mon, 07 Jan 2013 18:44:27 GMT

←Older revision		Revision as of 18:44, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2qvl.png\|left\|200px]]		[[Image:2qvl.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2qvl", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2qvl\| PDB=2qvl \| SCENE= }}		{{STRUCTURE_2qvl\| PDB=2qvl \| SCENE= }}

	===Crystal Structure of Diacylglycerol Kinase===		===Crystal Structure of Diacylglycerol Kinase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18611377}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18611377 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18611377}}		{{ABSTRACT_PUBMED_18611377}}

	==About this Structure==		==About this Structure==
-	~~2QVL~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].	+	[[2qvl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18611377~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018611377</ref><references group="xtra"/>
	[[Category: Diacylglycerol kinase]]		[[Category: Diacylglycerol kinase]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
Line 34:		Line 22:
	[[Category: Native protein]]		[[Category: Native protein]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:53:24 2009''

OCA at 18:53, 17 February 2009

OCA — Tue, 17 Feb 2009 18:53:24 GMT

←Older revision		Revision as of 18:53, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2QVL is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].	+	2QVL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].

	==Reference==		==Reference==
-	Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases., Miller DJ, Jerga A, Rock CO, White SW, Structure. 2008 Jul;16(7):1036-46. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18611377 18611377]~~	+	<ref group="xtra">PMID:18611377</ref><references group="xtra"/>
	[[Category: Diacylglycerol kinase]]		[[Category: Diacylglycerol kinase]]
-	[[Category: Single protein]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
	[[Category: Jerga, A.]]		[[Category: Jerga, A.]]
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	[[Category: Transferase]]		[[Category: Transferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 6 09~~:53:~~36 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:53:24 2009''

OCA at 06:53, 6 August 2008

OCA — Wed, 06 Aug 2008 06:53:37 GMT

←Older revision		Revision as of 06:53, 6 August 2008
Line 1:		Line 1:
-	[[Image:2qvl.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2qvl.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2qvl\| PDB=2qvl \| SCENE= }}		{{STRUCTURE_2qvl\| PDB=2qvl \| SCENE= }}

-	~~'''~~Crystal Structure of Diacylglycerol Kinase~~'''~~	+	===Crystal Structure of Diacylglycerol Kinase===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18611377}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18611377 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18611377}}

	==About this Structure==		==About this Structure==
	2QVL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].		2QVL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].
		+
		+	==Reference==
		+	Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases., Miller DJ, Jerga A, Rock CO, White SW, Structure. 2008 Jul;16(7):1036-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18611377 18611377]
	[[Category: Diacylglycerol kinase]]		[[Category: Diacylglycerol kinase]]
	[[Category: Single protein]]		[[Category: Single protein]]
Line 25:		Line 35:
	[[Category: Native protein]]		[[Category: Native protein]]
	[[Category: Transferase]]		[[Category: Transferase]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 18 12~~:04:10 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 6 09:53:36 2008''

OCA at 09:04, 18 June 2008

OCA — Wed, 18 Jun 2008 09:04:15 GMT

←Older revision		Revision as of 09:04, 18 June 2008
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2qvl.jpg\|left\|200px]]

-	The ~~entry 2qvl~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2qvl", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2qvl\| PDB=2qvl \| SCENE= }}

-	~~Authors: Miller, D.J., Jerga, A., Rock, C.O., White, S.W.~~	+	'''Crystal Structure of Diacylglycerol Kinase'''

-	Description: Crystal Structure of Diacylglycerol Kinase

-		+	==About this Structure==
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun ~~11 08~~:38:51 2008''	+	2QVL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVL OCA].
		+	[[Category: Diacylglycerol kinase]]
		+	[[Category: Single protein]]
		+	[[Category: Staphylococcus aureus]]
		+	[[Category: Jerga, A.]]
		+	[[Category: Miller, D J.]]
		+	[[Category: Rock, C O.]]
		+	[[Category: White, S W.]]
		+	[[Category: Alpha-beta domain 1]]
		+	[[Category: Beta sandwich domain 2]]
		+	[[Category: Native protein]]
		+	[[Category: Transferase]]
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 18 12:04:10 2008''