2r29 - Revision history

OCA at 04:11, 2 July 2021

OCA — Fri, 02 Jul 2021 04:11:52 GMT

←Older revision		Revision as of 04:11, 2 July 2021
Line 1:		Line 1:

	==Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography==		==Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography==
-	<StructureSection load='2r29' size='340' side='right' caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='2r29' size='340' side='right'caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Den26 Den26] and [~~http~~://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2R29 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Den26 Den26] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R29 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 DEN26])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 DEN26])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [~~http~~://pdbe.org/2r29 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2r29 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2r29 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [https://pdbe.org/2r29 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [https://www.ebi.ac.uk/pdbsum/2r29 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r29 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 2r29" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2r29" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Monoclonal Antibodies 3D structures\|Monoclonal Antibodies 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Den26]]		[[Category: Den26]]
		+	[[Category: Large Structures]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Battisti, A J]]		[[Category: Battisti, A J]]

OCA at 19:00, 24 January 2018

OCA — Wed, 24 Jan 2018 19:00:43 GMT

←Older revision		Revision as of 19:00, 24 January 2018
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r29_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r29_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 2r29" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2r29" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[3D structures of monoclonal antibody\|3D structures of monoclonal antibody]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:41, 25 October 2017

OCA — Wed, 25 Oct 2017 07:41:21 GMT

←Older revision		Revision as of 07:41, 25 October 2017
Line 1:		Line 1:
		+
	==Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography==		==Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography==
	<StructureSection load='2r29' size='340' side='right' caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2r29' size='340' side='right' caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Den26 Den26] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Den26 Den26] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 DEN26])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 DEN26])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://pdbe.org/2r29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://pdbe.org/2r29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2r29 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 28:

	==See Also==		==See Also==
-	*[[~~Monoclonal Antibody~~\|~~Monoclonal Antibody~~]]	+	*[[3D structures of monoclonal antibody\|3D structures of monoclonal antibody]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 39:
	[[Category: Diamond, M S]]		[[Category: Diamond, M S]]
	[[Category: Fremont, D H]]		[[Category: Fremont, D H]]
-	[[Category: Holdaway,H A]]	+	[[Category: Holdaway, H A]]
	[[Category: Kostyuchenko, V K]]		[[Category: Kostyuchenko, V K]]
	[[Category: Kuhn, R J]]		[[Category: Kuhn, R J]]
Line 45:		Line 46:
	[[Category: Roehrig, J T]]		[[Category: Roehrig, J T]]
	[[Category: Rossmann, M G]]		[[Category: Rossmann, M G]]
-	[[Category: Sedlak,D]]	+	[[Category: Sedlak, D]]
-	[[Category: Sukupolvi-petty,S]]	+	[[Category: Sukupolvi-petty, S]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Capsid protein]]		[[Category: Capsid protein]]

OCA at 09:49, 8 February 2016

OCA — Mon, 08 Feb 2016 09:49:56 GMT

←Older revision		Revision as of 09:49, 8 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r29 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:22, 10 September 2015

OCA — Thu, 10 Sep 2015 10:22:50 GMT

←Older revision		Revision as of 10:22, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2r29' size='340' side='right' caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='2r29' size='340' side='right' caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Dengue_virus_2_thailand/16681/84 Dengue virus 2 thailand/16681/84~~] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Den26 Den26] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 ~~Dengue virus 2 Thailand/16681/84~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 DEN26])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://pdbe.org/2r29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2r29" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Dengue virus 2 thailand/16681/84~~]]	+	[[Category: Den26]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Battisti, A J]]		[[Category: Battisti, A J]]

OCA at 13:54, 19 January 2015

OCA — Mon, 19 Jan 2015 13:54:37 GMT

←Older revision		Revision as of 13:54, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2_thailand/16681/84 Dengue virus 2 thailand/16681/84] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2_thailand/16681/84 Dengue virus 2 thailand/16681/84] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 Dengue virus 2 Thailand/16681/84])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 Dengue virus 2 Thailand/16681/84])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Dengue virus 2 thailand/16681/84]]		[[Category: Dengue virus 2 thailand/16681/84]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Battisti, A J.]]	+	[[Category: Battisti, A J]]
-	[[Category: Chipman, P R.]]	+	[[Category: Chipman, P R]]
-	[[Category: Diamond, M S.]]	+	[[Category: Diamond, M S]]
-	[[Category: Fremont, D H.]]	+	[[Category: Fremont, D H]]
	[[Category: Holdaway,H A]]		[[Category: Holdaway,H A]]
-	[[Category: Kostyuchenko, V K.]]	+	[[Category: Kostyuchenko, V K]]
-	[[Category: Kuhn, R J.]]	+	[[Category: Kuhn, R J]]
-	[[Category: Lok, S M.]]	+	[[Category: Lok, S M]]
-	[[Category: Nybakken, G E.]]	+	[[Category: Nybakken, G E]]
-	[[Category: Roehrig, J T.]]	+	[[Category: Roehrig, J T]]
-	[[Category: Rossmann, M G.]]	+	[[Category: Rossmann, M G]]
-	[[Category: Sedlak,D.]]	+	[[Category: Sedlak,D]]
-	[[Category: Sukupolvi-petty,S.]]	+	[[Category: Sukupolvi-petty,S]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Capsid protein]]		[[Category: Capsid protein]]

OCA at 06:56, 29 September 2014

OCA — Mon, 29 Sep 2014 06:56:29 GMT

←Older revision		Revision as of 06:56, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2r29.~~png\|left~~\|200px]]	+	==Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography==
		+	<StructureSection load='2r29' size='340' side='right' caption='[[2r29]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2_thailand/16681/84 Dengue virus 2 thailand/16681/84] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R29 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">E protein ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31634 Dengue virus 2 Thailand/16681/84])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r29 RCSB], [http://www.ebi.ac.uk/pdbsum/2r29 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r2/2r29_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The monoclonal antibody 1A1D-2 has been shown to strongly neutralize dengue virus serotypes 1, 2 and 3, primarily by inhibiting attachment to host cells. A crystal structure of its antigen binding fragment (Fab) complexed with domain III of the viral envelope glycoprotein, E, showed that the epitope would be partially occluded in the known structure of the mature dengue virus. Nevertheless, antibody could bind to the virus at 37 degrees C, suggesting that the virus is in dynamic motion making hidden epitopes briefly available. A cryo-electron microscope image reconstruction of the virus:Fab complex showed large changes in the organization of the E protein that exposed the epitopes on two of the three E molecules in each of the 60 icosahedral asymmetric units of the virus. The changes in the structure of the viral surface are presumably responsible for inhibiting attachment to cells.

-	~~{{STRUCTURE_2r29\| PDB=2r29 \| SCENE= }}~~	+	Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.,Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG Nat Struct Mol Biol. 2008 Mar;15(3):312-7. Epub 2008 Feb 10. PMID:18264114<ref>PMID:18264114</ref>

-	~~===Neutralization~~ of ~~dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18264114}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2r29]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Dengue_virus_2_thailand/16681/84 Dengue virus 2 thailand/16681/84] and [http://en~~.~~wikipedia.org~~/~~wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA].~~	+

	==See Also==		==See Also==
	*[[Monoclonal Antibody\|Monoclonal Antibody]]		*[[Monoclonal Antibody\|Monoclonal Antibody]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018264114<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Dengue virus 2 thailand/16681/84]]		[[Category: Dengue virus 2 thailand/16681/84]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]

OCA at 09:45, 20 October 2012

OCA — Sat, 20 Oct 2012 09:45:42 GMT

←Older revision		Revision as of 09:45, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2r29]] is a 3 chain structure ~~of [[Monoclonal Antibody]]~~ with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~] and [http://en.wikipedia.org/wiki/~~Viruses Viruses~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA].	+	[[2r29]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2_thailand/16681/84 Dengue virus 2 thailand/16681/84] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA].

	==See Also==		==See Also==
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	==Reference==		==Reference==
	<ref group="xtra">PMID:018264114</ref><references group="xtra"/>		<ref group="xtra">PMID:018264114</ref><references group="xtra"/>
		+	[[Category: Dengue virus 2 thailand/16681/84]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Viruses]]
	[[Category: Battisti, A J.]]		[[Category: Battisti, A J.]]
	[[Category: Chipman, P R.]]		[[Category: Chipman, P R.]]

OCA: Protected "2r29" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 23:52:11 GMT

Protected "2r29" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:52, 25 July 2012

OCA at 23:52, 25 July 2012

OCA — Wed, 25 Jul 2012 23:52:10 GMT

←Older revision		Revision as of 23:52, 25 July 2012
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-	{{Seed}}
	[[Image:2r29.png\|left\|200px]]		[[Image:2r29.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2r29\| PDB=2r29 \| SCENE= }}		{{STRUCTURE_2r29\| PDB=2r29 \| SCENE= }}

	===Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography===		===Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18264114}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_18264114}}		{{ABSTRACT_PUBMED_18264114}}

	==About this Structure==		==About this Structure==
-	~~2R29~~ is a 3 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/~~Dengue_virus_2 Dengue virus 2~~] and [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA].	+	[[2r29]] is a 3 chain structure of [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R29 OCA].
		+
		+	==See Also==
		+	*[[Monoclonal Antibody\|Monoclonal Antibody]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18264114~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018264114</ref><references group="xtra"/>
-	~~[[Category: Dengue virus 2]]~~	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
		+	[[Category: Viruses]]
	[[Category: Battisti, A J.]]		[[Category: Battisti, A J.]]
	[[Category: Chipman, P R.]]		[[Category: Chipman, P R.]]
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	[[Category: Transmembrane]]		[[Category: Transmembrane]]
	[[Category: Viral nucleoprotein]]		[[Category: Viral nucleoprotein]]
-	[[Category: Viral protein/immune system complex]]	+	[[Category: Viral protein-immune system complex]]
	[[Category: Virion]]		[[Category: Virion]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:06:26 2009''