2rgs - Revision history

OCA at 11:56, 30 August 2023

OCA — Wed, 30 Aug 2023 11:56:59 GMT

←Older revision		Revision as of 11:56, 30 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.13Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [https://pdbe.org/2rgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [https://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [https://pdbe.org/2rgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [https://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/IGG2B_MOUSE IGG2B_MOUSE]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 2rgs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2rgs" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Monoclonal Antibodies 3D structures\|Monoclonal Antibodies 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 38:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Dohnalek, J]]	+	[[Category: Dohnalek J]]
-	[[Category: Duskova, J]]	+	[[Category: Duskova J]]
-	[[Category: Hasek, J]]	+	[[Category: Hasek J]]
-	[[Category: Kolenko, P]]	+	[[Category: Kolenko P]]
-	[[Category: Skalova, T]]	+	[[Category: Skalova T]]
-	~~[[Category: Fc-fragment]]~~	+
-	~~[[Category: Glycosylation]]~~	+
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Immunoglobulin~~]]	+

OCA at 07:47, 16 March 2022

OCA — Wed, 16 Mar 2022 07:47:39 GMT

←Older revision		Revision as of 07:47, 16 March 2022
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	<StructureSection load='2rgs' size='340' side='right'caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>		<StructureSection load='2rgs' size='340' side='right'caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2RGS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [~~http~~://pdbe.org/2rgs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [https://pdbe.org/2rgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [https://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:12, 10 June 2020

OCA — Wed, 10 Jun 2020 07:12:07 GMT

←Older revision		Revision as of 07:12, 10 June 2020
Line 1:		Line 1:

	==FC-fragment of monoclonal antibody IGG2B from Mus musculus==		==FC-fragment of monoclonal antibody IGG2B from Mus musculus==
-	<StructureSection load='2rgs' size='340' side='right' caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>	+	<StructureSection load='2rgs' size='340' side='right'caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2RGS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://pdbe.org/2rgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://pdbe.org/2rgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Dohnalek, J]]		[[Category: Dohnalek, J]]

OCA at 11:10, 5 September 2018

OCA — Wed, 05 Sep 2018 11:10:55 GMT

←Older revision		Revision as of 11:10, 5 September 2018
Line 1:		Line 1:
		+
	==FC-fragment of monoclonal antibody IGG2B from Mus musculus==		==FC-fragment of monoclonal antibody IGG2B from Mus musculus==
	<StructureSection load='2rgs' size='340' side='right' caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>		<StructureSection load='2rgs' size='340' side='right' caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://pdbe.org/2rgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://pdbe.org/2rgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rgs_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rgs_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:04, 9 February 2016

OCA — Tue, 09 Feb 2016 17:04:23 GMT

←Older revision		Revision as of 17:04, 9 February 2016
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://pdbe.org/2rgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rgs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2rgs" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:46, 19 January 2015

OCA — Mon, 19 Jan 2015 16:46:16 GMT

←Older revision		Revision as of 16:46, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Dohnalek, J.]]	+	[[Category: Dohnalek, J]]
-	[[Category: Duskova, J.]]	+	[[Category: Duskova, J]]
-	[[Category: Hasek, J.]]	+	[[Category: Hasek, J]]
-	[[Category: Kolenko, P.]]	+	[[Category: Kolenko, P]]
-	[[Category: Skalova, T.]]	+	[[Category: Skalova, T]]
	[[Category: Fc-fragment]]		[[Category: Fc-fragment]]
	[[Category: Glycosylation]]		[[Category: Glycosylation]]
	[[Category: Immune system]]		[[Category: Immune system]]
	[[Category: Immunoglobulin]]		[[Category: Immunoglobulin]]

OCA at 19:27, 30 September 2014

OCA — Tue, 30 Sep 2014 19:27:17 GMT

←Older revision		Revision as of 19:27, 30 September 2014
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-	[[~~Image~~:2rgs.~~png\|left~~\|200px]]	+	==FC-fragment of monoclonal antibody IGG2B from Mus musculus==
		+	<StructureSection load='2rgs' size='340' side='right' caption='[[2rgs]], [[Resolution\|resolution]] 2.13Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RGS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rgs RCSB], [http://www.ebi.ac.uk/pdbsum/2rgs PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rgs_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of the Fc fragment of monoclonal antibody IgG2b from hybridom M75 of Mus musculus has been determined by single crystal X-ray diffraction. This is the first report of the structure of the murine immunoglobulin isotype IgG2b. The structure refined at 2.1 A resolution provides more detailed structural information about native oligosaccharides than was previously available. High-quality Fourier maps provide a clear identification of alpha-l-fucose with partial occupancy in the first branch of the antennary oligosaccharides. A unique Fc:Fc interaction was observed at the C(H)2-C(H)3 interface.

-	~~{{STRUCTURE_2rgs\| PDB=2rgs \| SCENE= }}~~	+	New insights into intra- and intermolecular interactions of immunoglobulins: crystal structure of mouse IgG2b-Fc at 2.1-A resolution.,Kolenko P, Dohnalek J, Duskova J, Skalova T, Collard R, Hasek J Immunology. 2009 Mar;126(3):378-85. Epub 2008 Sep 6. PMID:18783468<ref>PMID:18783468</ref>

-	~~===FC-fragment~~ of ~~monoclonal antibody IGG2B from Mus musculus===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18783468}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2rgs]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018783468<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Dohnalek, J.]]		[[Category: Dohnalek, J.]]

OCA: Protected "2rgs" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 19:31:28 GMT

Protected "2rgs" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:31, 7 January 2013

OCA at 19:31, 7 January 2013

OCA — Mon, 07 Jan 2013 19:31:26 GMT

←Older revision		Revision as of 19:31, 7 January 2013
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-	{{Seed}}
	[[Image:2rgs.png\|left\|200px]]		[[Image:2rgs.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2rgs", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_2rgs\| PDB=2rgs \| SCENE= }}		{{STRUCTURE_2rgs\| PDB=2rgs \| SCENE= }}

	===FC-fragment of monoclonal antibody IGG2B from Mus musculus===		===FC-fragment of monoclonal antibody IGG2B from Mus musculus===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18783468}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18783468 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_18783468}}		{{ABSTRACT_PUBMED_18783468}}

	==About this Structure==		==About this Structure==
-	~~2RGS~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA].	+	[[2rgs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18783468~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018783468</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Dohnalek, J.]]		[[Category: Dohnalek, J.]]
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	[[Category: Immune system]]		[[Category: Immune system]]
	[[Category: Immunoglobulin]]		[[Category: Immunoglobulin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:23:51 2009''

OCA at 09:23, 17 February 2009

OCA — Tue, 17 Feb 2009 09:23:53 GMT

←Older revision		Revision as of 09:23, 17 February 2009
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	{{Seed}}		{{Seed}}
-	[[Image:2rgs.~~jpg~~\|left\|200px]]	+	[[Image:2rgs.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	2RGS is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA].	+	2RGS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGS OCA].

	==Reference==		==Reference==
-	New insights into intra- and intermolecular interactions of immunoglobulins: crystal structure of mouse IgG2b-Fc at 2.1-A resolution., Kolenko P, Dohnalek J, Duskova J, Skalova T, Collard R, Hasek J, Immunology. 2008 Sep 6. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18783468 18783468]~~	+	<ref group="xtra">PMID:18783468</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Single protein]]
	[[Category: Dohnalek, J.]]		[[Category: Dohnalek, J.]]
	[[Category: Duskova, J.]]		[[Category: Duskova, J.]]
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	[[Category: Immunoglobulin]]		[[Category: Immunoglobulin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 8 09~~:23:~~46 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:23:51 2009''