2uyh - Revision history

OCA at 14:58, 13 December 2023

OCA — Wed, 13 Dec 2023 14:58:06 GMT

←Older revision		Revision as of 14:58, 13 December 2023
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	<StructureSection load='2uyh' size='340' side='right'caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>		<StructureSection load='2uyh' size='340' side='right'caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UYH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UYH FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SAH:S~~-~~ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.63Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;~~'>[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</~~div~~><~~/td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [https://pdbe.org/2uyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [https://www.ebi.ac.uk/pdbsum/2uyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [https://pdbe.org/2uyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [https://www.ebi.ac.uk/pdbsum/2uyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.	+	[https://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus x pritchett and stillman 1919~~]]	+	[[Category: Haemophilus haemolyticus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Daujotyte, D]]	+	[[Category: Daujotyte D]]
-	[[Category: Grazulis, S]]	+	[[Category: Grazulis S]]
-	~~[[Category: Base flipping]]~~	+
-	~~[[Category: Dna methyltransferase]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Restriction system]]~~	+
-	~~[[Category: S-adenosyl-l-methionine]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 10:39, 7 July 2021

OCA — Wed, 07 Jul 2021 10:39:46 GMT

OCA at 07:36, 24 July 2019

OCA — Wed, 24 Jul 2019 07:36:54 GMT

←Older revision		Revision as of 07:36, 24 July 2019
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	==HhaI DNA methyltransferase S87Q-Q237S mutant complex with 13mer GCGC- GMGC oligonucleotide and SAH==		==HhaI DNA methyltransferase S87Q-Q237S mutant complex with 13mer GCGC- GMGC oligonucleotide and SAH==
-	<StructureSection load='2uyh' size='340' side='right' caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>	+	<StructureSection load='2uyh' size='340' side='right'caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>
Line 24:		Line 24:

	==See Also==		==See Also==
-	*[[DNA methyltransferase\|DNA methyltransferase]]	+	*[[DNA methyltransferase 3D structures\|DNA methyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus x pritchett and stillman 1919]]		[[Category: Bacillus x pritchett and stillman 1919]]
		+	[[Category: Large Structures]]
	[[Category: Daujotyte, D]]		[[Category: Daujotyte, D]]
	[[Category: Grazulis, S]]		[[Category: Grazulis, S]]

OCA at 08:40, 12 September 2018

OCA — Wed, 12 Sep 2018 08:40:41 GMT

←Older revision		Revision as of 08:40, 12 September 2018
Line 1:		Line 1:
-	==~~HHAI~~ DNA ~~METHYLTRANSFERASE~~ S87Q-Q237S ~~MUTANT COMPLEX WITH 13MER~~ GCGC-GMGC ~~OLIGONUCLEOTIDE AND~~ SAH==	+
		+	==HhaI DNA methyltransferase S87Q-Q237S mutant complex with 13mer GCGC- GMGC oligonucleotide and SAH==
	<StructureSection load='2uyh' size='340' side='right' caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>		<StructureSection load='2uyh' size='340' side='right' caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Haemophilus_haemolyticus Haemophilus haemolyticus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [http://www.ebi.ac.uk/pdbsum/2uyh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [http://pdbe.org/2uyh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [http://www.ebi.ac.uk/pdbsum/2uyh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uyh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[DNA methyltransferase\|DNA methyltransferase]]		*[[DNA methyltransferase\|DNA methyltransferase]]
-	*[[HhaI DNA methyltransferase\|HhaI DNA methyltransferase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Haemophilus haemolyticus~~]]	+	[[Category: Bacillus x pritchett and stillman 1919]]
	[[Category: Daujotyte, D]]		[[Category: Daujotyte, D]]
	[[Category: Grazulis, S]]		[[Category: Grazulis, S]]

OCA at 18:21, 25 December 2014

OCA — Thu, 25 Dec 2014 18:21:31 GMT

←Older revision		Revision as of 18:21, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>		<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [http://www.ebi.ac.uk/pdbsum/2uyh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [http://www.ebi.ac.uk/pdbsum/2uyh PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Haemophilus haemolyticus]]		[[Category: Haemophilus haemolyticus]]
-	[[Category: Daujotyte, D.]]	+	[[Category: Daujotyte, D]]
-	[[Category: Grazulis, S.]]	+	[[Category: Grazulis, S]]
	[[Category: Base flipping]]		[[Category: Base flipping]]
	[[Category: Dna methyltransferase]]		[[Category: Dna methyltransferase]]

OCA at 09:05, 29 September 2014

OCA — Mon, 29 Sep 2014 09:05:46 GMT

←Older revision		Revision as of 09:05, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:2uyh.png\|left\|200px]]~~	+	==HHAI DNA METHYLTRANSFERASE S87Q-Q237S MUTANT COMPLEX WITH 13MER GCGC-GMGC OLIGONUCLEOTIDE AND SAH==
-		+	<StructureSection load='2uyh' size='340' side='right' caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>
-	~~{{STRUCTURE_2uyh\| PDB=2uyh \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UYH FirstGlance]. <br>
-	===HHAI DNA METHYLTRANSFERASE S87Q-Q237S MUTANT COMPLEX WITH 13MER GCGC-GMGC OLIGONUCLEOTIDE AND SAH===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>
-	[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [http://www.ebi.ac.uk/pdbsum/2uyh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uyh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[DNA methyltransferase\|DNA methyltransferase]]		*[[DNA methyltransferase\|DNA methyltransferase]]
		+	*[[HhaI DNA methyltransferase\|HhaI DNA methyltransferase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Haemophilus haemolyticus]]		[[Category: Haemophilus haemolyticus]]
	[[Category: Daujotyte, D.]]		[[Category: Daujotyte, D.]]

OCA at 19:55, 20 October 2012

OCA — Sat, 20 Oct 2012 19:55:12 GMT

←Older revision		Revision as of 19:55, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[2uyh]] is a 3 chain structure ~~of [[DNA methyltransferase]]~~ with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].	+	[[2uyh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].

	==See Also==		==See Also==

OCA: Protected "2uyh" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 08:53:29 GMT

Protected "2uyh" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:53, 27 July 2012

OCA at 08:53, 27 July 2012

OCA — Fri, 27 Jul 2012 08:53:28 GMT

←Older revision		Revision as of 08:53, 27 July 2012
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-	{{Seed}}
	[[Image:2uyh.png\|left\|200px]]		[[Image:2uyh.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2uyh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2uyh\| PDB=2uyh \| SCENE= }}		{{STRUCTURE_2uyh\| PDB=2uyh \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2UYH~~ is a 3 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].	+	[[2uyh]] is a 3 chain structure of [[DNA methyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].
		+
		+	==See Also==
		+	*[[DNA methyltransferase\|DNA methyltransferase]]
	[[Category: Haemophilus haemolyticus]]		[[Category: Haemophilus haemolyticus]]
	[[Category: Daujotyte, D.]]		[[Category: Daujotyte, D.]]
Line 24:		Line 20:
	[[Category: S-adenosyl-l-methionine]]		[[Category: S-adenosyl-l-methionine]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:02:20 2009''

OCA at 00:02, 18 February 2009

OCA — Wed, 18 Feb 2009 00:02:24 GMT

←Older revision		Revision as of 00:02, 18 February 2009
Line 1:		Line 1:
-	[[Image:2uyh.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2uyh.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2uyh\| PDB=2uyh \| SCENE= }}		{{STRUCTURE_2uyh\| PDB=2uyh \| SCENE= }}

-	~~'''~~HHAI DNA METHYLTRANSFERASE S87Q-Q237S MUTANT COMPLEX WITH 13MER GCGC-GMGC OLIGONUCLEOTIDE AND SAH~~'''~~	+	===HHAI DNA METHYLTRANSFERASE S87Q-Q237S MUTANT COMPLEX WITH 13MER GCGC-GMGC OLIGONUCLEOTIDE AND SAH===


	==About this Structure==		==About this Structure==
-	2UYH is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].	+	2UYH is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_haemolyticus Haemophilus haemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA].
	[[Category: Haemophilus haemolyticus]]		[[Category: Haemophilus haemolyticus]]
-	[[Category: Protein complex]]
	[[Category: Daujotyte, D.]]		[[Category: Daujotyte, D.]]
	[[Category: Grazulis, S.]]		[[Category: Grazulis, S.]]
Line 24:		Line 24:
	[[Category: S-adenosyl-l-methionine]]		[[Category: S-adenosyl-l-methionine]]
	[[Category: Transferase]]		[[Category: Transferase]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 28 09~~:16:~~21 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:02:20 2009''

←Older revision		Revision as of 10:39, 7 July 2021
Line 3:		Line 3:
	<StructureSection load='2uyh' size='340' side='right'caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>		<StructureSection load='2uyh' size='340' side='right'caption='[[2uyh]], [[Resolution\|resolution]] 2.63Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2UYH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2uyh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UYH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UYH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[10mh\|10mh]], [[1fjx\|1fjx]], [[1hmy\|1hmy]], [[1m0e\|1m0e]], [[1mht\|1mht]], [[1skm\|1skm]], [[1svu\|1svu]], [[2c7o\|2c7o]], [[2c7p\|2c7p]], [[2c7q\|2c7q]], [[2c7r\|2c7r]], [[2hmy\|2hmy]], [[2uyc\|2uyc]], [[3mht\|3mht]], [[4mht\|4mht]], [[5mht\|5mht]], [[6mht\|6mht]], [[7mht\|7mht]], [[8mht\|8mht]], [[9mht\|9mht]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [~~http~~://pdbe.org/2uyh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2uyh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uyh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uyh OCA], [https://pdbe.org/2uyh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uyh RCSB], [https://www.ebi.ac.uk/pdbsum/2uyh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uyh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.	+	[[https://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]