2v4n - Revision history

OCA at 15:05, 13 December 2023

OCA — Wed, 13 Dec 2023 15:05:32 GMT

←Older revision		Revision as of 15:05, 13 December 2023
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	<StructureSection load='2v4n' size='340' side='right'caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2v4n' size='340' side='right'caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Salty Salty~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2v4o\|2v4o]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [https://pdbe.org/2v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [https://www.ebi.ac.uk/pdbsum/2v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4n ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [https://pdbe.org/2v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [https://www.ebi.ac.uk/pdbsum/2v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4n ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/SURE_SALTY SURE_SALTY] Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.[HAMAP-Rule:MF_00060]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Salty~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-	[[Category: Anju, P]]	+	[[Category: Anju P]]
-	[[Category: Murthy~~, M R.N~~]]	+	[[Category: Murthy MRN]]
-	[[Category: Savithri~~, H S]]~~	+	[[Category: Savithri HS]]
-	~~[[Category: Divalent metal ion]]~~	+
-	~~[[Category: Domain swapping]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Mononucleotidase]]~~	+
-	~~[[Category: Phosphatase]]~~	+
-	~~[[Category: Rossmann fold]]~~	+
-	~~[[Category: Stationary phase]]~~	+
-	~~[[Category: Sur e]]~~	+
-	~~[[Category: Survival protein~~]]	+

OCA at 10:41, 7 July 2021

OCA — Wed, 07 Jul 2021 10:41:57 GMT

←Older revision		Revision as of 10:41, 7 July 2021
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	<StructureSection load='2v4n' size='340' side='right'caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2v4n' size='340' side='right'caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2V4N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4N FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v4o\|2v4o]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2v4o\|2v4o]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [~~http~~://pdbe.org/2v4n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2v4n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [https://pdbe.org/2v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [https://www.ebi.ac.uk/pdbsum/2v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4n ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 12:09, 10 May 2019

OCA — Fri, 10 May 2019 12:09:17 GMT

←Older revision		Revision as of 12:09, 10 May 2019
Line 1:		Line 1:

	==Crystal structure of Salmonella typhimurium SurE at 1.7 angstrom resolution in orthorhombic form==		==Crystal structure of Salmonella typhimurium SurE at 1.7 angstrom resolution in orthorhombic form==
-	<StructureSection load='2v4n' size='340' side='right' caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='2v4n' size='340' side='right'caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>		<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Salty]]		[[Category: Salty]]
	[[Category: Anju, P]]		[[Category: Anju, P]]

OCA at 08:46, 12 September 2018

OCA — Wed, 12 Sep 2018 08:46:13 GMT

←Older revision		Revision as of 08:46, 12 September 2018
Line 1:		Line 1:

-	==~~CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT~~ 1.7 ~~ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM~~==	+	==Crystal structure of Salmonella typhimurium SurE at 1.7 angstrom resolution in orthorhombic form==
	<StructureSection load='2v4n' size='340' side='right' caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2v4n' size='340' side='right' caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4n_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4n_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:44, 11 August 2016

OCA — Thu, 11 Aug 2016 14:44:35 GMT

←Older revision		Revision as of 14:44, 11 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM==		==CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM==
	<StructureSection load='2v4n' size='340' side='right' caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2v4n' size='340' side='right' caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v4o\|2v4o]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v4o\|2v4o]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [http://www.ebi.ac.uk/pdbsum/2v4n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [http://pdbe.org/2v4n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [http://www.ebi.ac.uk/pdbsum/2v4n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4n ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v4n ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2v4n" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Salmonella enterica subsp. enterica serovar typhimurium~~]]	+	[[Category: Salty]]
	[[Category: Anju, P]]		[[Category: Anju, P]]
	[[Category: Murthy, M R.N]]		[[Category: Murthy, M R.N]]

OCA at 14:04, 19 January 2015

OCA — Mon, 19 Jan 2015 14:04:08 GMT

←Older revision		Revision as of 14:04, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>		<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v4o\|2v4o]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v4o\|2v4o]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [http://www.ebi.ac.uk/pdbsum/2v4n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [http://www.ebi.ac.uk/pdbsum/2v4n PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
-	[[Category: Anju, P.]]	+	[[Category: Anju, P]]
-	[[Category: Murthy, M R.N.]]	+	[[Category: Murthy, M R.N]]
-	[[Category: Savithri, H S.]]	+	[[Category: Savithri, H S]]
	[[Category: Divalent metal ion]]		[[Category: Divalent metal ion]]
	[[Category: Domain swapping]]		[[Category: Domain swapping]]

OCA at 01:36, 1 October 2014

OCA — Wed, 01 Oct 2014 01:36:26 GMT

←Older revision		Revision as of 01:36, 1 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2v4n.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM==
		+	<StructureSection load='2v4n' size='340' side='right' caption='[[2v4n]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4N FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2v4o\|2v4o]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4n RCSB], [http://www.ebi.ac.uk/pdbsum/2v4n PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4n_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	SurE, the stationary-phase survival protein of Salmonella typhimurium, forms part of a stress survival operon regulated by the stationary-phase RNA polymerase alternative sigma factor. SurE is known to improve bacterial viability during stress conditions. It functions as a phosphatase specific to nucleoside monophosphates. In the present study we reported the X-ray crystal structure of SurE from Salmonella typhimurium. The protein crystallized in two forms: orthorhombic F222; and monoclinic C2. The two structures were determined to resolutions of 1.7 and 2.7 A, respectively. The protein exists as a domain-swapped dimer. The residue D230 is involved in several interactions that are probably crucial for domain swapping. A divalent metal ion is found at the active site of the enzyme, which is consistent with the divalent metal ion-dependent activity of the enzyme. Interactions of the conserved DD motif present at the N-terminus with the phosphate and the Mg(2+) present in the active site suggest that these residues play an important role in enzyme activity. The divalent metal ion specificity and the kinetic constants of SurE were determined using the generic phosphatase substrate para-nitrophenyl phosphate. The enzyme was inactive in the absence of divalent cations and was most active in the presence of Mg(2+). Thermal denaturation studies showed that S. typhimurium SurE is much less stable than its homologues and an attempt was made to understand the molecular basis of the lower thermal stability based on solvation free-energy. This is the first detailed crystal structure analysis of SurE from a mesophilic organism.

-	~~{{STRUCTURE_2v4n\| PDB=2v4n \| SCENE= }}~~	+	Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium.,Pappachan A, Savithri HS, Murthy MR FEBS J. 2008 Dec;275(23):5855-64. PMID:19021761<ref>PMID:19021761</ref>

-	~~===CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19021761}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2v4n]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Salmonella_enterica_subsp~~.~~_enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019021761<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Anju, P.]]		[[Category: Anju, P.]]

OCA: Protected "2v4n" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 18:15:30 GMT

Protected "2v4n" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:15, 7 January 2013

OCA at 18:15, 7 January 2013

OCA — Mon, 07 Jan 2013 18:15:28 GMT

←Older revision		Revision as of 18:15, 7 January 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:2v4n.png\|left\|200px]]
-	[[Image:2v4n.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2v4n", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2v4n\| PDB=2v4n \| SCENE= }}		{{STRUCTURE_2v4n\| PDB=2v4n \| SCENE= }}

	===CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM===		===CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19021761}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19021761 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19021761}}		{{ABSTRACT_PUBMED_19021761}}

	==About this Structure==		==About this Structure==
-	~~2V4N~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Salmonella_typhimurium~~ Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA].	+	[[2v4n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA].

	==Reference==		==Reference==
-	~~Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium., Pappachan A, Savithri HS, Murthy MR, FEBS J. 2008 Dec;275(23):5855-64.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/19021761 19021761]~~	+	<ref group="xtra">PMID:019021761</ref><references group="xtra"/>
-	[[Category: Salmonella typhimurium]]	+	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Anju, P.]]		[[Category: Anju, P.]]
	[[Category: Murthy, M R.N.]]		[[Category: Murthy, M R.N.]]
Line 37:		Line 25:
	[[Category: Sur e]]		[[Category: Sur e]]
	[[Category: Survival protein]]		[[Category: Survival protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:53:31 2008''

OCA at 12:53, 10 December 2008

OCA — Wed, 10 Dec 2008 12:53:32 GMT

←Older revision		Revision as of 12:53, 10 December 2008
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2v4n.jpg\|left\|200px]]

-	The ~~entry 2v4n~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2v4n", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2v4n\| PDB=2v4n \| SCENE= }}

-	~~Authors: Anju, P., Savithri, H.S., Murthy, M.R.N~~.	+	===CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM SURE AT 1.7 ANGSTROM RESOLUTION IN ORTHORHOMBIC FORM===

-	Description: Crystal structure of Salmonella typhimurium SurE at 1.7 angstrom resolution in orthorhombic form

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 8 09~~:13:49 2008''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19021761}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19021761 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19021761}}
		+
		+	==About this Structure==
		+	2V4N is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4N OCA].
		+
		+	==Reference==
		+	Structural and functional studies on a mesophilic stationary phase survival protein (Sur E) from Salmonella typhimurium., Pappachan A, Savithri HS, Murthy MR, FEBS J. 2008 Dec;275(23):5855-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19021761 19021761]
		+	[[Category: Salmonella typhimurium]]
		+	[[Category: Anju, P.]]
		+	[[Category: Murthy, M R.N.]]
		+	[[Category: Savithri, H S.]]
		+	[[Category: Divalent metal ion]]
		+	[[Category: Domain swapping]]
		+	[[Category: Hydrolase]]
		+	[[Category: Mononucleotidase]]
		+	[[Category: Phosphatase]]
		+	[[Category: Rossmann fold]]
		+	[[Category: Stationary phase]]
		+	[[Category: Sur e]]
		+	[[Category: Survival protein]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 14:53:31 2008''