2v4v - Revision history

OCA at 15:05, 13 December 2023

OCA — Wed, 13 Dec 2023 15:05:41 GMT

←Older revision		Revision as of 15:05, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2v4v' size='340' side='right'caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2v4v' size='340' side='right'caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35319 Atcc 35319~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruminiclostridium_cellulolyticum Ruminiclostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [https://pdbe.org/2v4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [https://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [https://pdbe.org/2v4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [https://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q0PRN1_RUMCH Q0PRN1_RUMCH]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35319]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Abbott, D W~~]]	+	[[Category: Ruminiclostridium cellulolyticum]]
-	[[Category: ~~Boraston, A B~~]]	+	[[Category: Abbott DW]]
-	[[Category: ~~Bueren, A Lammerts van~~]]	+	[[Category: Boraston AB]]
-	[[Category: Coutinho~~, P M~~]]	+	[[Category: Coutinho PM]]
-	[[Category: Ficko-Blean, E]]	+	[[Category: Ficko-Blean E]]
-	[[Category: Gilbert~~, H J~~]]	+	[[Category: Gilbert HJ]]
-	[[Category: Henrissat, B]]	+	[[Category: Henrissat B]]
-	[[Category: ~~Cccbm6]]~~	+	[[Category: Lammerts van Bueren A]]
-	~~[[Category: Family 6 carbohydrate binding module]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 12:38, 23 March 2022

OCA — Wed, 23 Mar 2022 12:38:36 GMT

←Older revision		Revision as of 12:38, 23 March 2022
Line 3:		Line 3:
	<StructureSection load='2v4v' size='340' side='right'caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2v4v' size='340' side='right'caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_35319 Atcc 35319]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2V4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35319 Atcc 35319]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [~~http~~://pdbe.org/2v4v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [https://pdbe.org/2v4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [https://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 11:19, 17 June 2020

OCA — Wed, 17 Jun 2020 11:19:47 GMT

←Older revision		Revision as of 11:19, 17 June 2020
Line 1:		Line 1:

	==Crystal Structure of a Family 6 Carbohydrate-Binding Module from Clostridium cellulolyticum in complex with xylose==		==Crystal Structure of a Family 6 Carbohydrate-Binding Module from Clostridium cellulolyticum in complex with xylose==
-	<StructureSection load='2v4v' size='340' side='right' caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='2v4v' size='340' side='right'caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35319 Atcc 35319]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2V4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35319 Atcc 35319]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://pdbe.org/2v4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://pdbe.org/2v4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 28:		Line 28:

	==See Also==		==See Also==
-	*[[Galactosidase\|Galactosidase]]	+	*[[Galactosidase 3D structures\|Galactosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35319]]		[[Category: Atcc 35319]]
		+	[[Category: Large Structures]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 08:53, 12 September 2018

OCA — Wed, 12 Sep 2018 08:53:26 GMT

←Older revision		Revision as of 08:53, 12 September 2018
Line 1:		Line 1:

-	==~~CRYSTAL STRUCTURE OF A FAMILY~~ 6 ~~CARBOHYDRATE~~-~~BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE~~==	+	==Crystal Structure of a Family 6 Carbohydrate-Binding Module from Clostridium cellulolyticum in complex with xylose==
	<StructureSection load='2v4v' size='340' side='right' caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2v4v' size='340' side='right' caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~[clostridium]_cellulolyticum [clostridium] cellulolyticum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35319 Atcc 35319]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://pdbe.org/2v4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://pdbe.org/2v4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4v_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4v_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 35319]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]
-	[[Category: Bueren, A Lammerts ~~Van~~]]	+	[[Category: Bueren, A Lammerts van]]
	[[Category: Coutinho, P M]]		[[Category: Coutinho, P M]]
	[[Category: Ficko-Blean, E]]		[[Category: Ficko-Blean, E]]

OCA at 08:49, 11 August 2016

OCA — Thu, 11 Aug 2016 08:49:08 GMT

←Older revision		Revision as of 08:49, 11 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF A FAMILY 6 CARBOHYDRATE-BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE==		==CRYSTAL STRUCTURE OF A FAMILY 6 CARBOHYDRATE-BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE==
	<StructureSection load='2v4v' size='340' side='right' caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2v4v' size='340' side='right' caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_cellulolyticum Clostridium~~ cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/[clostridium]_cellulolyticum [clostridium] cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://pdbe.org/2v4v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v4v ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v4v ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2v4v" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Clostridium cellulolyticum]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 15:56, 19 January 2015

OCA — Mon, 19 Jan 2015 15:56:04 GMT

←Older revision		Revision as of 15:56, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>		<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Clostridium cellulolyticum]]		[[Category: Clostridium cellulolyticum]]
-	[[Category: Abbott, D W.]]	+	[[Category: Abbott, D W]]
-	[[Category: Boraston, A B.]]	+	[[Category: Boraston, A B]]
-	[[Category: Bueren, A Lammerts Van.]]	+	[[Category: Bueren, A Lammerts Van]]
-	[[Category: Coutinho, P M.]]	+	[[Category: Coutinho, P M]]
-	[[Category: Ficko-Blean, E.]]	+	[[Category: Ficko-Blean, E]]
-	[[Category: Gilbert, H J.]]	+	[[Category: Gilbert, H J]]
-	[[Category: Henrissat, B.]]	+	[[Category: Henrissat, B]]
	[[Category: Cccbm6]]		[[Category: Cccbm6]]
	[[Category: Family 6 carbohydrate binding module]]		[[Category: Family 6 carbohydrate binding module]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 08:05, 29 September 2014

OCA — Mon, 29 Sep 2014 08:05:55 GMT

←Older revision		Revision as of 08:05, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2v4v.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF A FAMILY 6 CARBOHYDRATE-BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE==
		+	<StructureSection load='2v4v' size='340' side='right' caption='[[2v4v]], [[Resolution\|resolution]] 1.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V4V FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v4v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v4v RCSB], [http://www.ebi.ac.uk/pdbsum/2v4v PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/2v4v_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Carbohydrate binding modules (CBMs) play important biological roles in targeting appended catalytic modules to their dedicated substrate(s) within complex macromolecular structures such as the plant cell wall. Because of the large potential in ligand diversity within nature and our continually expanding knowledge of sequence-based information of carbohydrate-modifying enzymes, empirical determination of CBM binding specificity and identification of novel mechanisms in carbohydrate recognition by these proteins have become time-consuming and complicated processes. To help overcome these experimental hurdles, we present here a predictive model for family 6 CBMs (CBM6) that is based upon several factors, including phylogenetic relatedness, and structural and functional evidence. This analysis has determined that five regions within the binding site, termed A-E, play key roles in ligand selection and affinity. Regions A-C are located in a primary subsite and contribute mainly to binding energy and selection for O2, O3, and O4 equatorial hydroxyls. Region D appears to determine whether the CBM will interact with internal or terminal structures of the carbohydrate ligand. Region E displays the largest degree of variation and is thus predicted to make the most significant contribution to specificity. This model is supported by the biochemical properties and structure of a CBM6 from Clostridium cellulolyticum (CcCBM6), which we also report here. The protein bound specifically to xylose and the nonreducing of end of polymers containing this pentose sugar. The crystal structure of CcCBM6 in complex with xylose showed that a tyrosine residue made hydrophobic contacts with the unsubstituted C5 atom of xylose and sterically hindered decorations at this sugar ring position. The mechanism, by which the CBM recognizes xylose but not glucose, a specificity not previously observed in this family, supports our predictive model that holds that variation in region E plays a key role in the diverse ligand selection evident in CBM6.

-	~~{{STRUCTURE_2v4v\| PDB=2v4v \| SCENE= }}~~	+	Analysis of the Structural and Functional Diversity of Plant Cell Wall Specific Family 6 Carbohydrate Binding Modules.,Abbott DW, Ficko-Blean E, van Bueren AL, Rogowski A, Cartmell A, Coutinho PM, Henrissat B, Gilbert HJ, Boraston AB Biochemistry. 2009 Oct 9. PMID:19788273<ref>PMID:19788273</ref>

-	~~===CRYSTAL STRUCTURE OF A FAMILY 6 CARBOHYDRATE-BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19788273}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2v4v]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA].~~	+

	==See Also==		==See Also==
	*[[Galactosidase\|Galactosidase]]		*[[Galactosidase\|Galactosidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019788273<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Clostridium cellulolyticum]]		[[Category: Clostridium cellulolyticum]]
	[[Category: Abbott, D W.]]		[[Category: Abbott, D W.]]

OCA at 18:37, 20 October 2012

OCA — Sat, 20 Oct 2012 18:37:41 GMT

←Older revision		Revision as of 18:37, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2v4v]] is a 1 chain structure ~~of [[Galactosidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA].	+	[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA].

	==See Also==		==See Also==

OCA at 04:41, 27 July 2012

OCA — Fri, 27 Jul 2012 04:41:13 GMT

←Older revision		Revision as of 04:41, 27 July 2012
Line 1:		Line 1:
	[[Image:2v4v.png\|left\|200px]]		[[Image:2v4v.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2v4v", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2v4v\| PDB=2v4v \| SCENE= }}		{{STRUCTURE_2v4v\| PDB=2v4v \| SCENE= }}

	===CRYSTAL STRUCTURE OF A FAMILY 6 CARBOHYDRATE-BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE===		===CRYSTAL STRUCTURE OF A FAMILY 6 CARBOHYDRATE-BINDING MODULE FROM CLOSTRIDIUM CELLULOLYTICUM IN COMPLEX WITH XYLOSE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19788273}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19788273 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19788273}}		{{ABSTRACT_PUBMED_19788273}}

	==About this Structure==		==About this Structure==
-	[[2v4v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA].	+	[[2v4v]] is a 1 chain structure of [[Galactosidase]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_cellulolyticum Clostridium cellulolyticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V4V OCA].
		+
		+	==See Also==
		+	*[[Galactosidase\|Galactosidase]]

	==Reference==		==Reference==

OCA: Protected "2v4v" [edit=sysop:move=sysop]

OCA — Wed, 22 Jun 2011 15:56:28 GMT

Protected "2v4v" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:56, 22 June 2011