2v9o - Revision history

OCA at 15:11, 13 December 2023

OCA — Wed, 13 Dec 2023 15:11:17 GMT

←Older revision		Revision as of 15:11, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2v9o' size='340' side='right'caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='2v9o' size='340' side='right'caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9O FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [https://pdbe.org/2v9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [https://www.ebi.ac.uk/pdbsum/2v9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [https://pdbe.org/2v9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [https://www.ebi.ac.uk/pdbsum/2v9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RHAD_ECOLI RHAD_ECOLI]] Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.[HAMAP-Rule:MF_00770]	+	[https://www.uniprot.org/uniprot/RHAD_ECOLI RHAD_ECOLI] Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.[HAMAP-Rule:MF_00770]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Rhamnulose-1-phosphate aldolase]]~~	+	[[Category: Grueninger D]]
-	[[Category: Grueninger, D]]	+	[[Category: Schulz GE]]
-	[[Category: Schulz~~, G E]]~~	+
-	~~[[Category: 2-ketose degradation]]~~	+
-	~~[[Category: Aggregation]]~~	+
-	~~[[Category: Aldolase]]~~	+
-	~~[[Category: Class ii]]~~	+
-	~~[[Category: Cleavage of l-rhamnulose-1-phosphate to dihydroxyacetoneph bacterial l-rhamnose metabolism]]~~	+
-	~~[[Category: Entropy index]]~~	+
-	~~[[Category: Fibrillation]]~~	+
-	~~[[Category: Interface design]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Oligomerization]]~~	+
-	~~[[Category: Protein engineering]]~~	+
-	~~[[Category: Protein-protein interface]]~~	+
-	~~[[Category: Rare sugar]]~~	+
-	~~[[Category: Rhamnose metabolism]]~~	+
-	~~[[Category: Surface mutation]]~~	+
-	~~[[Category: Zinc enzyme~~]]	+

OCA at 10:43, 7 July 2021

OCA — Wed, 07 Jul 2021 10:43:17 GMT

←Older revision		Revision as of 10:43, 7 July 2021
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	<StructureSection load='2v9o' size='340' side='right'caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='2v9o' size='340' side='right'caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2V9O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [~~http~~://pdbe.org/2v9o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2v9o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [https://pdbe.org/2v9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [https://www.ebi.ac.uk/pdbsum/2v9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RHAD_ECOLI RHAD_ECOLI]] Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.[HAMAP-Rule:MF_00770]	+	[[https://www.uniprot.org/uniprot/RHAD_ECOLI RHAD_ECOLI]] Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.[HAMAP-Rule:MF_00770]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:39, 24 July 2019

OCA — Wed, 24 Jul 2019 07:39:26 GMT

←Older revision		Revision as of 07:39, 24 July 2019
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	==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M- T109F-E192A)==		==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M- T109F-E192A)==
-	<StructureSection load='2v9o' size='340' side='right' caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='2v9o' size='340' side='right'caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>		<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Aldolase\|Aldolase]]	+	*[[Aldolase 3D structures\|Aldolase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Rhamnulose-1-phosphate aldolase]]		[[Category: Rhamnulose-1-phosphate aldolase]]
	[[Category: Grueninger, D]]		[[Category: Grueninger, D]]

OCA at 08:44, 12 September 2018

OCA — Wed, 12 Sep 2018 08:44:23 GMT

←Older revision		Revision as of 08:44, 12 September 2018
Line 1:		Line 1:

-	==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)==	+	==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M- T109F-E192A)==
	<StructureSection load='2v9o' size='340' side='right' caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='2v9o' size='340' side='right' caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v9o_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v9o_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:48, 5 August 2016

OCA — Fri, 05 Aug 2016 21:48:17 GMT

←Older revision		Revision as of 21:48, 5 August 2016
Line 1:		Line 1:
		+
	==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)==		==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)==
	<StructureSection load='2v9o' size='340' side='right' caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='2v9o' size='340' side='right' caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [http://www.ebi.ac.uk/pdbsum/2v9o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [http://pdbe.org/2v9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [http://www.ebi.ac.uk/pdbsum/2v9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v9o ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2v9o" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Rhamnulose-1-phosphate aldolase]]		[[Category: Rhamnulose-1-phosphate aldolase]]
	[[Category: Grueninger, D]]		[[Category: Grueninger, D]]

OCA at 22:11, 25 December 2014

OCA — Thu, 25 Dec 2014 22:11:29 GMT

←Older revision		Revision as of 22:11, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>		<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [http://www.ebi.ac.uk/pdbsum/2v9o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [http://www.ebi.ac.uk/pdbsum/2v9o PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RHAD_ECOLI RHAD_ECOLI]] Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.[HAMAP-Rule:MF_00770]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Rhamnulose-1-phosphate aldolase]]		[[Category: Rhamnulose-1-phosphate aldolase]]
-	[[Category: Grueninger, D.]]	+	[[Category: Grueninger, D]]
-	[[Category: Schulz, G E.]]	+	[[Category: Schulz, G E]]
	[[Category: 2-ketose degradation]]		[[Category: 2-ketose degradation]]
	[[Category: Aggregation]]		[[Category: Aggregation]]

OCA at 09:08, 29 September 2014

OCA — Mon, 29 Sep 2014 09:08:22 GMT

←Older revision		Revision as of 09:08, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2v9o.~~png~~\|~~left~~\|200px]]	+	==L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)==
		+	<StructureSection load='2v9o' size='340' side='right' caption='[[2v9o]], [[Resolution\|resolution]] 1.95Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V9O FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gt7\|1gt7]], [[1ojr\|1ojr]], [[2uyu\|2uyu]], [[2v2b\|2v2b]], [[2uyv\|2uyv]], [[2v29\|2v29]], [[2v2a\|2v2a]], [[2v9e\|2v9e]], [[2v9f\|2v9f]], [[2v9g\|2v9g]], [[2v9i\|2v9i]], [[2v9l\|2v9l]], [[2v9m\|2v9m]], [[2v9n\|2v9n]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v9o RCSB], [http://www.ebi.ac.uk/pdbsum/2v9o PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v9o_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The analysis of natural contact interfaces between protein subunits and between proteins has disclosed some general rules governing their association. We have applied these rules to produce a number of novel assemblies, demonstrating that a given protein can be engineered to form contacts at various points of its surface. Symmetry plays an important role because it defines the multiplicity of a designed contact and therefore the number of required mutations. Some of the proteins needed only a single side-chain alteration in order to associate to a higher-order complex. The mobility of the buried side chains has to be taken into account. Four assemblies have been structurally elucidated. Comparisons between the designed contacts and the results will provide useful guidelines for the development of future architectures.

-	~~{{STRUCTURE_2v9o\| PDB=2v9o \| SCENE= }}~~	+	Designed protein-protein association.,Grueninger D, Treiber N, Ziegler MO, Koetter JW, Schulze MS, Schulz GE Science. 2008 Jan 11;319(5860):206-9. PMID:18187656<ref>PMID:18187656</ref>

-	~~===L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18187656}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2v9o]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA].~~	+

	==See Also==		==See Also==
	*[[Aldolase\|Aldolase]]		*[[Aldolase\|Aldolase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018187656<~~/~~ref~~><~~ref group="xtra">PMID:012962479</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Rhamnulose-1-phosphate aldolase]]		[[Category: Rhamnulose-1-phosphate aldolase]]

OCA at 22:14, 20 October 2012

OCA — Sat, 20 Oct 2012 22:14:33 GMT

←Older revision		Revision as of 22:14, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2v9o]] is a 2 chain structure ~~of [[Aldolase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA].	+	[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA].

	==See Also==		==See Also==

OCA at 15:40, 27 July 2012

OCA — Fri, 27 Jul 2012 15:40:16 GMT

←Older revision		Revision as of 15:40, 27 July 2012
Line 1:		Line 1:
	[[Image:2v9o.png\|left\|200px]]		[[Image:2v9o.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2v9o", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2v9o\| PDB=2v9o \| SCENE= }}		{{STRUCTURE_2v9o\| PDB=2v9o \| SCENE= }}

	===L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)===		===L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT A87M-T109F-E192A)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18187656}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18187656 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18187656}}		{{ABSTRACT_PUBMED_18187656}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Aldolase]]	+	*[[Aldolase\|Aldolase]]

	==Reference==		==Reference==

OCA at 06:15, 24 August 2011

OCA — Wed, 24 Aug 2011 06:15:53 GMT

←Older revision		Revision as of 06:15, 24 August 2011
Line 19:		Line 19:

	==About this Structure==		==About this Structure==
-	[[2v9o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA].	+	[[2v9o]] is a 2 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9O OCA].
		+
		+	==See Also==
		+	*[[Aldolase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18187656~~</ref><ref group="xtra">PMID:~~12962479~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018187656</ref><ref group="xtra">PMID:012962479</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Rhamnulose-1-phosphate aldolase]]		[[Category: Rhamnulose-1-phosphate aldolase]]
Line 32:		Line 35:
	[[Category: Class ii]]		[[Category: Class ii]]
	[[Category: Cleavage of l-rhamnulose-1-phosphate to dihydroxyacetoneph bacterial l-rhamnose metabolism]]		[[Category: Cleavage of l-rhamnulose-1-phosphate to dihydroxyacetoneph bacterial l-rhamnose metabolism]]
-	[[Category: Cytoplasm]]
	[[Category: Entropy index]]		[[Category: Entropy index]]
	[[Category: Fibrillation]]		[[Category: Fibrillation]]
Line 44:		Line 46:
	[[Category: Rhamnose metabolism]]		[[Category: Rhamnose metabolism]]
	[[Category: Surface mutation]]		[[Category: Surface mutation]]
-	[[Category: Zinc]]
	[[Category: Zinc enzyme]]		[[Category: Zinc enzyme]]