2vak - Revision history

OCA at 15:12, 13 December 2023

OCA — Wed, 13 Dec 2023 15:12:46 GMT

←Older revision		Revision as of 15:12, 13 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VAK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.34Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [https://pdbe.org/2vak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [https://www.ebi.ac.uk/pdbsum/2vak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vak ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [https://pdbe.org/2vak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [https://www.ebi.ac.uk/pdbsum/2vak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vak ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9E6F8_9VIRU Q9E6F8_9VIRU]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 38:
	[[Category: Avian orthoreovirus]]		[[Category: Avian orthoreovirus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Benavente, J]]	+	[[Category: Benavente J]]
-	[[Category: Fox~~, G C~~]]	+	[[Category: Fox GC]]
-	[[Category: Guardado-Calvo, P]]	+	[[Category: Guardado-Calvo P]]
-	[[Category: Hermo-Parrado~~, X L~~]]	+	[[Category: Hermo-Parrado XL]]
-	[[Category: Llamas-Saiz~~, A L~~]]	+	[[Category: Llamas-Saiz AL]]
-	[[Category: Martinez-Costas, J]]	+	[[Category: Martinez-Costas J]]
-	~~[[Category: Raaij, M J.van~~]]	+	[[Category: Vazquez-Iglesias L]]
-	[[Category: Vazquez-Iglesias, L]]	+	[[Category: Van Raaij MJ]]
-	[[Category: ~~Double-stranded rna binding]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 10:43, 7 July 2021

OCA — Wed, 07 Jul 2021 10:43:33 GMT

←Older revision		Revision as of 10:43, 7 July 2021
Line 3:		Line 3:
	<StructureSection load='2vak' size='340' side='right'caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>		<StructureSection load='2vak' size='340' side='right'caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VAK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [~~http~~://pdbe.org/2vak PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vak PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vak ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [https://pdbe.org/2vak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [https://www.ebi.ac.uk/pdbsum/2vak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vak ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 2vak" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2vak" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:10, 10 May 2019

OCA — Fri, 10 May 2019 12:10:41 GMT

←Older revision		Revision as of 12:10, 10 May 2019
Line 1:		Line 1:

	==Crystal structure of the avian reovirus inner capsid protein sigmaA==		==Crystal structure of the avian reovirus inner capsid protein sigmaA==
-	<StructureSection load='2vak' size='340' side='right' caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>	+	<StructureSection load='2vak' size='340' side='right'caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Avian orthoreovirus]]		[[Category: Avian orthoreovirus]]
		+	[[Category: Large Structures]]
	[[Category: Benavente, J]]		[[Category: Benavente, J]]
	[[Category: Fox, G C]]		[[Category: Fox, G C]]

OCA at 06:46, 15 February 2018

OCA — Thu, 15 Feb 2018 06:46:57 GMT

←Older revision		Revision as of 06:46, 15 February 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF THE AVIAN REOVIRUS INNER CAPSID PROTEIN SIGMAA~~==	+
		+	==Crystal structure of the avian reovirus inner capsid protein sigmaA==
	<StructureSection load='2vak' size='340' side='right' caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>		<StructureSection load='2vak' size='340' side='right' caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://pdbe.org/2vak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://pdbe.org/2vak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vak ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vak_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vak_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 36:		Line 37:
	[[Category: Llamas-Saiz, A L]]		[[Category: Llamas-Saiz, A L]]
	[[Category: Martinez-Costas, J]]		[[Category: Martinez-Costas, J]]
-	[[Category: Raaij, M J.~~Van~~]]	+	[[Category: Raaij, M J.van]]
	[[Category: Vazquez-Iglesias, L]]		[[Category: Vazquez-Iglesias, L]]
	[[Category: Double-stranded rna binding]]		[[Category: Double-stranded rna binding]]
	[[Category: Rna]]		[[Category: Rna]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 02:46, 10 February 2016

OCA — Wed, 10 Feb 2016 02:46:14 GMT

←Older revision		Revision as of 02:46, 10 February 2016
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://pdbe.org/2vak PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vak ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2vak" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:27, 19 January 2015

OCA — Mon, 19 Jan 2015 13:27:16 GMT

←Older revision		Revision as of 13:27, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Avian orthoreovirus]]		[[Category: Avian orthoreovirus]]
-	[[Category: Benavente, J.]]	+	[[Category: Benavente, J]]
-	[[Category: Fox, G C.]]	+	[[Category: Fox, G C]]
-	[[Category: Guardado-Calvo, P.]]	+	[[Category: Guardado-Calvo, P]]
-	[[Category: Hermo-Parrado, X L.]]	+	[[Category: Hermo-Parrado, X L]]
-	[[Category: Llamas-Saiz, A L.]]	+	[[Category: Llamas-Saiz, A L]]
-	[[Category: Martinez-Costas, J.]]	+	[[Category: Martinez-Costas, J]]
-	[[Category: Raaij, M J.Van.]]	+	[[Category: Raaij, M J.Van]]
-	[[Category: Vazquez-Iglesias, L.]]	+	[[Category: Vazquez-Iglesias, L]]
	[[Category: Double-stranded rna binding]]		[[Category: Double-stranded rna binding]]
	[[Category: Rna]]		[[Category: Rna]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 01:19, 1 October 2014

OCA — Wed, 01 Oct 2014 01:19:39 GMT

←Older revision		Revision as of 01:19, 1 October 2014
Line 1:		Line 1:
-	[[~~Image~~:2vak.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE AVIAN REOVIRUS INNER CAPSID PROTEIN SIGMAA==
		+	<StructureSection load='2vak' size='340' side='right' caption='[[2vak]], [[Resolution\|resolution]] 2.34Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VAK FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vak OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vak RCSB], [http://www.ebi.ac.uk/pdbsum/2vak PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/va/2vak_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Avian reovirus, an important avian pathogen, expresses eight structural and four nonstructural proteins. The structural sigmaA protein is a major component of the inner capsid, clamping together lambdaA building blocks. sigmaA has also been implicated in the resistance of avian reovirus to the antiviral action of interferon by strongly binding double-stranded RNA in the host cell cytoplasm and thus inhibiting activation of the double-stranded RNA-dependent protein kinase. We have solved the structure of bacterially expressed sigmaA by molecular replacement and refined it using data to 2.3-A resolution. Twelve sigmaA molecules are present in the P1 unit cell, arranged as two short double helical hexamers. A positively charged patch is apparent on the surface of sigmaA on the inside of this helix and mutation of either of two key arginine residues (Arg155 and Arg273) within this patch abolishes double-stranded RNA binding. The structural data, together with gel shift assay, electron microscopy, and sedimentation velocity centrifugation results, provide evidence for cooperative binding of sigmaA to double-stranded RNA. The minimal length of double-stranded RNA required for sigmaA binding was observed to be 14 to 18 bp.

-	~~{{STRUCTURE_2vak\| PDB=2vak \| SCENE= }}~~	+	Crystal structure of the avian reovirus inner capsid protein sigmaA.,Guardado-Calvo P, Vazquez-Iglesias L, Martinez-Costas J, Llamas-Saiz AL, Schoehn G, Fox GC, Hermo-Parrado XL, Benavente J, van Raaij MJ J Virol. 2008 Nov;82(22):11208-16. Epub 2008 Sep 17. PMID:18799570<ref>PMID:18799570</ref>

-	~~===CRYSTAL STRUCTURE OF THE AVIAN REOVIRUS INNER CAPSID PROTEIN SIGMAA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18799570}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2vak]] is~~ a ~~12 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Avian_orthoreovirus Avian orthoreovirus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018799570<~~/~~ref~~><~~ref group="xtra">PMID:017565188</ref><references group="xtra"~~/>	+
	[[Category: Avian orthoreovirus]]		[[Category: Avian orthoreovirus]]
	[[Category: Benavente, J.]]		[[Category: Benavente, J.]]

OCA at 13:08, 30 January 2013

OCA — Wed, 30 Jan 2013 13:08:54 GMT

←Older revision		Revision as of 13:08, 30 January 2013
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	[[Image:2vak.png\|left\|200px]]		[[Image:2vak.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_2vak\| PDB=2vak \| SCENE= }}		{{STRUCTURE_2vak\| PDB=2vak \| SCENE= }}

	===CRYSTAL STRUCTURE OF THE AVIAN REOVIRUS INNER CAPSID PROTEIN SIGMAA===		===CRYSTAL STRUCTURE OF THE AVIAN REOVIRUS INNER CAPSID PROTEIN SIGMAA===

-
-	<!--
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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18799570~~</ref><ref group="xtra">PMID:~~17565188~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018799570</ref><ref group="xtra">PMID:017565188</ref><references group="xtra"/>
	[[Category: Avian orthoreovirus]]		[[Category: Avian orthoreovirus]]
	[[Category: Benavente, J.]]		[[Category: Benavente, J.]]

OCA: Protected "2vak" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 18:10:03 GMT

Protected "2vak" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:10, 14 March 2011

OCA at 18:10, 14 March 2011

OCA — Mon, 14 Mar 2011 18:10:01 GMT

←Older revision		Revision as of 18:10, 14 March 2011
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-	{{Seed}}
	[[Image:2vak.png\|left\|200px]]		[[Image:2vak.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2VAK~~ is a 12 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA].	+	[[2vak]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_orthoreovirus Avian orthoreovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VAK OCA].

	==Reference==		==Reference==
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	[[Category: Rna]]		[[Category: Rna]]
	[[Category: Viral protein]]		[[Category: Viral protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 09:30:04 2010''