2voo - Revision history

OCA at 15:27, 13 December 2023

OCA — Wed, 13 Dec 2023 15:27:02 GMT

←Older revision		Revision as of 15:27, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2voo' size='340' side='right'caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2voo' size='340' side='right'caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1s7a\|1s7a]]~~, [[~~1zh5~~\|~~1zh5~~]]~~, [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [https://pdbe.org/2voo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [https://www.ebi.ac.uk/pdbsum/2voo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [https://pdbe.org/2voo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [https://www.ebi.ac.uk/pdbsum/2voo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LA_HUMAN LA_HUMAN] Binds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.<ref>PMID:3192525</ref> <ref>PMID:2470590</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Conte~~, M R~~]]	+	[[Category: Conte MR]]
-	[[Category: Curry, S]]	+	[[Category: Curry S]]
-	[[Category: Kotik-Kogan, O]]	+	[[Category: Kotik-Kogan O]]
-	[[Category: Sanfelice, D]]	+	[[Category: Sanfelice D]]
-	[[Category: Valentine~~, E R]]~~	+	[[Category: Valentine ER]]
-	~~[[Category: La motif]]~~	+
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Polymorphism]]~~	+
-	~~[[Category: Rna binding protein]]~~	+
-	~~[[Category: Rna maturation]]~~	+
-	~~[[Category: Rna recognition motif]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Rna-binding protein]]~~	+
-	~~[[Category: Systemic lupus erythematosus~~]]	+

OCA at 11:42, 30 March 2022

OCA — Wed, 30 Mar 2022 11:42:22 GMT

←Older revision		Revision as of 11:42, 30 March 2022
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	<StructureSection load='2voo' size='340' side='right'caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2voo' size='340' side='right'caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VOO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [~~http~~://pdbe.org/2voo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2voo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [https://pdbe.org/2voo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [https://www.ebi.ac.uk/pdbsum/2voo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:16, 25 June 2020

OCA — Thu, 25 Jun 2020 08:16:14 GMT

←Older revision		Revision as of 08:16, 25 June 2020
Line 1:		Line 1:

	==Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU==		==Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU==
-	<StructureSection load='2voo' size='340' side='right' caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='2voo' size='340' side='right'caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VOO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://pdbe.org/2voo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://pdbe.org/2voo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Conte, M R]]		[[Category: Conte, M R]]
	[[Category: Curry, S]]		[[Category: Curry, S]]

OCA at 20:42, 19 September 2018

OCA — Wed, 19 Sep 2018 20:42:11 GMT

←Older revision		Revision as of 20:42, 19 September 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF~~ N-~~TERMINAL DOMAINS OF HUMAN LA PROTEIN COMPLEXED WITH~~ RNA ~~OLIGOMER~~ UUUUUUUU==	+
		+	==Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU==
	<StructureSection load='2voo' size='340' side='right' caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2voo' size='340' side='right' caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://pdbe.org/2voo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://pdbe.org/2voo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2voo ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/2voo_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/2voo_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	[[Category: Nucleus]]		[[Category: Nucleus]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
		+	[[Category: Polymorphism]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]
	[[Category: Rna maturation]]		[[Category: Rna maturation]]

OCA at 10:55, 9 February 2016

OCA — Tue, 09 Feb 2016 10:55:12 GMT

←Older revision		Revision as of 10:55, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2voo' size='340' side='right' caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2voo' size='340' side='right' caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://pdbe.org/2voo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2voo ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2voo" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Conte, M R]]		[[Category: Conte, M R]]
	[[Category: Curry, S]]		[[Category: Curry, S]]

OCA at 17:26, 19 January 2015

OCA — Mon, 19 Jan 2015 17:26:41 GMT

←Older revision		Revision as of 17:26, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Conte, M R.]]	+	[[Category: Conte, M R]]
-	[[Category: Curry, S.]]	+	[[Category: Curry, S]]
-	[[Category: Kotik-Kogan, O.]]	+	[[Category: Kotik-Kogan, O]]
-	[[Category: Sanfelice, D.]]	+	[[Category: Sanfelice, D]]
-	[[Category: Valentine, E R.]]	+	[[Category: Valentine, E R]]
	[[Category: La motif]]		[[Category: La motif]]
	[[Category: Nucleus]]		[[Category: Nucleus]]

OCA at 01:53, 1 October 2014

OCA — Wed, 01 Oct 2014 01:53:59 GMT

←Older revision		Revision as of 01:53, 1 October 2014
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-	[[~~Image:~~2voo.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF N-TERMINAL DOMAINS OF HUMAN LA PROTEIN COMPLEXED WITH RNA OLIGOMER UUUUUUUU==
		+	<StructureSection load='2voo' size='340' side='right' caption='[[2voo]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VOO FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1s7a\|1s7a]], [[1zh5\|1zh5]], [[1yty\|1yty]], [[1s79\|1s79]], [[2vod\|2vod]], [[2vop\|2vop]], [[2von\|2von]], [[1owx\|1owx]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2voo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2voo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2voo RCSB], [http://www.ebi.ac.uk/pdbsum/2voo PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vo/2voo_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The eukaryotic La protein recognizes the 3' poly(U) sequences of nascent RNA polymerase III transcripts to assist folding and maturation. The 3' ends of such RNAs are bound by the N-terminal domain of La (LaNTD). We have solved the crystal structures of four LaNTD:RNA complexes, each containing a different single-stranded RNA oligomer, and compared them to the structure of a previously published LaNTD:RNA complex containing partially duplex RNA. The presence of purely single-stranded RNA in the binding pocket at the interface between the La motif and RRM domains allows significantly closer contact with the 3' end of the RNA. Comparison of the different LaNTD:RNA complexes identifies a conserved set of interactions with the last two nucleotides at the 3' end of the RNA ligand that are key to binding. Strikingly, we also observe two alternative conformations of bound ssRNA, indicative of an unexpected degree of plasticity in the modes of RNA binding.

-	~~{{STRUCTURE_2voo\| PDB=2voo \| SCENE= }}~~	+	Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human La protein.,Kotik-Kogan O, Valentine ER, Sanfelice D, Conte MR, Curry S Structure. 2008 Jun;16(6):852-62. PMID:18547518<ref>PMID:18547518</ref>

-	~~===CRYSTAL STRUCTURE OF N-TERMINAL DOMAINS OF HUMAN LA PROTEIN COMPLEXED WITH RNA OLIGOMER UUUUUUUU===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18547518}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2voo]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018547518<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Conte, M R.]]		[[Category: Conte, M R.]]

OCA: Protected "2voo" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 22:48:57 GMT

Protected "2voo" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:48, 7 January 2013

OCA at 22:48, 7 January 2013

OCA — Mon, 07 Jan 2013 22:48:54 GMT

←Older revision		Revision as of 22:48, 7 January 2013
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-	{{Seed}}
	[[Image:2voo.png\|left\|200px]]		[[Image:2voo.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2voo\| PDB=2voo \| SCENE= }}		{{STRUCTURE_2voo\| PDB=2voo \| SCENE= }}

	===CRYSTAL STRUCTURE OF N-TERMINAL DOMAINS OF HUMAN LA PROTEIN COMPLEXED WITH RNA OLIGOMER UUUUUUUU===		===CRYSTAL STRUCTURE OF N-TERMINAL DOMAINS OF HUMAN LA PROTEIN COMPLEXED WITH RNA OLIGOMER UUUUUUUU===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18547518}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18547518 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18547518}}		{{ABSTRACT_PUBMED_18547518}}

	==About this Structure==		==About this Structure==
-	~~2VOO~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA].	+	[[2voo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18547518~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018547518</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Conte, M R.]]		[[Category: Conte, M R.]]
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	[[Category: Nucleus]]		[[Category: Nucleus]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
-	[[Category: Polymorphism]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]
	[[Category: Rna maturation]]		[[Category: Rna maturation]]
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	[[Category: Rna-binding protein]]		[[Category: Rna-binding protein]]
	[[Category: Systemic lupus erythematosus]]		[[Category: Systemic lupus erythematosus]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:18:19 2009''

OCA at 07:18, 17 February 2009

OCA — Tue, 17 Feb 2009 07:18:21 GMT

←Older revision		Revision as of 07:18, 17 February 2009
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	==About this Structure==		==About this Structure==
-	2VOO is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA].	+	2VOO is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOO OCA].

	==Reference==		==Reference==
-	Structural analysis reveals conformational plasticity in the recognition of RNA 3' ends by the human la protein., Kotik-Kogan O, Valentine ER, Sanfelice D, Conte MR, Curry S, Structure. 2008 Jun;16(6):852-62. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18547518 18547518]~~	+	<ref group="xtra">PMID:18547518</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Single protein]]
	[[Category: Conte, M R.]]		[[Category: Conte, M R.]]
	[[Category: Curry, S.]]		[[Category: Curry, S.]]
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	[[Category: Systemic lupus erythematosus]]		[[Category: Systemic lupus erythematosus]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 2 21~~:48:~~09 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:18:19 2009''