2vqs - Revision history

OCA at 15:28, 13 December 2023

OCA — Wed, 13 Dec 2023 15:28:54 GMT

←Older revision		Revision as of 15:28, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2vqs' size='340' side='right'caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2vqs' size='340' side='right'caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Drome Drome~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VQS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VQS FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=BVD:5~~-~~BROMOVINYLDEOXYURIDINE'>BVD</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [https://pdbe.org/2vqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [https://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [https://pdbe.org/2vqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [https://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DNK_DROME DNK_DROME]] Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, deoxyadenosine, deoxycytidine and deoxyguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.<ref>PMID:10446143</ref> <ref>PMID:10692477</ref> <ref>PMID:16008571</ref>	+	[https://www.uniprot.org/uniprot/DNK_DROME DNK_DROME] Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, deoxyadenosine, deoxycytidine and deoxyguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.<ref>PMID:10446143</ref> <ref>PMID:10692477</ref> <ref>PMID:16008571</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</div>		</div>
	<div class="pdbe-citations 2vqs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2vqs" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Thymidine kinase\|Thymidine kinase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Deoxynucleoside kinase]]~~	+	[[Category: Drosophila melanogaster]]
-	~~[[Category: Drome~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Eklund, H]]	+	[[Category: Eklund H]]
-	[[Category: Mikkelsen~~, N E~~]]	+	[[Category: Mikkelsen NE]]
-	[[Category: Munch-Petersen, B]]	+	[[Category: Munch-Petersen B]]
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Complex]]~~	+
-	~~[[Category: Deoxyribonucleoside kinase]]~~	+
-	~~[[Category: Dna synthesis]]~~	+
-	~~[[Category: Drosophila]]~~	+
-	~~[[Category: Dttp]]~~	+
-	~~[[Category: Feedback inhibition]]~~	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Salvage pathway]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 11:44, 30 March 2022

OCA — Wed, 30 Mar 2022 11:44:05 GMT

←Older revision		Revision as of 11:44, 30 March 2022
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	<StructureSection load='2vqs' size='340' side='right'caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2vqs' size='340' side='right'caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VQS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VQS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [~~http~~://pdbe.org/2vqs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [https://pdbe.org/2vqs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [https://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DNK_DROME DNK_DROME]] Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, deoxyadenosine, deoxycytidine and deoxyguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.<ref>PMID:10446143</ref> <ref>PMID:10692477</ref> <ref>PMID:16008571</ref>	+	[[https://www.uniprot.org/uniprot/DNK_DROME DNK_DROME]] Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, deoxyadenosine, deoxycytidine and deoxyguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.<ref>PMID:10446143</ref> <ref>PMID:10692477</ref> <ref>PMID:16008571</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 2vqs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2vqs" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Thymidine kinase\|Thymidine kinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:22, 25 June 2020

OCA — Thu, 25 Jun 2020 08:22:45 GMT

←Older revision		Revision as of 08:22, 25 June 2020
Line 1:		Line 1:

	==Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase==		==Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase==
-	<StructureSection load='2vqs' size='340' side='right' caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='2vqs' size='340' side='right'caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VQS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VQS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://pdbe.org/2vqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://pdbe.org/2vqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	[[Category: Deoxynucleoside kinase]]		[[Category: Deoxynucleoside kinase]]
	[[Category: Drome]]		[[Category: Drome]]
		+	[[Category: Large Structures]]
	[[Category: Eklund, H]]		[[Category: Eklund, H]]
	[[Category: Mikkelsen, N E]]		[[Category: Mikkelsen, N E]]

OCA at 20:43, 19 September 2018

OCA — Wed, 19 Sep 2018 20:43:31 GMT

←Older revision		Revision as of 20:43, 19 September 2018
Line 1:		Line 1:
-	==~~STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE~~==	+
		+	==Structural Studies of Nucleoside Analog and Feedback Inhibitor Binding to Drosophila Melanogaster Multisubstrate Deoxyribonucleoside Kinase==
	<StructureSection load='2vqs' size='340' side='right' caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2vqs' size='340' side='right' caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://pdbe.org/2vqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://pdbe.org/2vqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vqs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vq/2vqs_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vq/2vqs_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 10:57, 9 February 2016

OCA — Tue, 09 Feb 2016 10:57:33 GMT

←Older revision		Revision as of 10:57, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2vqs' size='340' side='right' caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='2vqs' size='340' side='right' caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://pdbe.org/2vqs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vqs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2vqs" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Deoxynucleoside kinase]]		[[Category: Deoxynucleoside kinase]]
-	[[Category: ~~Drosophila melanogaster~~]]	+	[[Category: Drome]]
	[[Category: Eklund, H]]		[[Category: Eklund, H]]
	[[Category: Mikkelsen, N E]]		[[Category: Mikkelsen, N E]]

OCA at 06:25, 25 December 2014

OCA — Thu, 25 Dec 2014 06:25:19 GMT

←Older revision		Revision as of 06:25, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DNK_DROME DNK_DROME]] Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, deoxyadenosine, deoxycytidine and deoxyguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated.<ref>PMID:10446143</ref> <ref>PMID:10692477</ref> <ref>PMID:16008571</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	[[Category: Deoxynucleoside kinase]]		[[Category: Deoxynucleoside kinase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
-	[[Category: Eklund, H.]]	+	[[Category: Eklund, H]]
-	[[Category: Mikkelsen, N E.]]	+	[[Category: Mikkelsen, N E]]
-	[[Category: Munch-Petersen, B.]]	+	[[Category: Munch-Petersen, B]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Complex]]		[[Category: Complex]]

OCA at 01:54, 1 October 2014

OCA — Wed, 01 Oct 2014 01:54:38 GMT

←Older revision		Revision as of 01:54, 1 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2vqs.~~png~~\|~~left~~\|200px]]	+	==STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE==
		+	<StructureSection load='2vqs' size='340' side='right' caption='[[2vqs]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VQS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BVD:5-BROMOVINYLDEOXYURIDINE'>BVD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zm7\|1zm7]], [[2vpp\|2vpp]], [[2vp5\|2vp5]], [[1zmx\|1zmx]], [[2vp4\|2vp4]], [[1j90\|1j90]], [[2vp0\|2vp0]], [[2jcs\|2jcs]], [[1ot3\|1ot3]], [[2vp6\|2vp6]], [[1oe0\|1oe0]], [[2vp2\|2vp2]], [[2vp9\|2vp9]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vqs RCSB], [http://www.ebi.ac.uk/pdbsum/2vqs PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vq/2vqs_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Drosophila melanogaster multisubstrate deoxyribonucleoside kinase (dNK; EC 2.7.1.145) has a high turnover rate and a wide substrate range that makes it a very good candidate for gene therapy. This concept is based on introducing a suicide gene into malignant cells in order to activate a prodrug that eventually may kill the cell. To be able to optimize the function of dNK, it is vital to have structural information of dNK complexes. In this study we present crystal structures of dNK complexed with four different nucleoside analogs (floxuridine, brivudine, zidovudine and zalcitabine) and relate them to the binding of substrate and feedback inhibitors. dCTP and dGTP bind with the base in the substrate site, similarly to the binding of the feedback inhibitor dTTP. All nucleoside analogs investigated bound in a manner similar to that of the pyrimidine substrates, with many interactions in common. In contrast, the base of dGTP adopted a syn-conformation to adapt to the available space of the active site.

-	~~{{STRUCTURE_2vqs\| PDB=2vqs \| SCENE= }}~~	+	Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.,Mikkelsen NE, Munch-Petersen B, Eklund H FEBS J. 2008 May;275(9):2151-60. Epub 2008 Apr 1. PMID:18384378<ref>PMID:18384378</ref>

-	~~===STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18384378}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2vqs]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Drosophila_melanogaster Drosophila melanogaster]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018384378<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Deoxynucleoside kinase]]		[[Category: Deoxynucleoside kinase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]

OCA: Protected "2vqs" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 22:50:10 GMT

Protected "2vqs" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:50, 7 January 2013

OCA at 22:50, 7 January 2013

OCA — Mon, 07 Jan 2013 22:50:08 GMT

←Older revision		Revision as of 22:50, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2vqs.png\|left\|200px]]		[[Image:2vqs.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2vqs", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2vqs\| PDB=2vqs \| SCENE= }}		{{STRUCTURE_2vqs\| PDB=2vqs \| SCENE= }}

	===STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE===		===STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18384378}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18384378 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18384378}}		{{ABSTRACT_PUBMED_18384378}}

	==About this Structure==		==About this Structure==
-	~~2VQS~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA].	+	[[2vqs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18384378~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018384378</ref><references group="xtra"/>
	[[Category: Deoxynucleoside kinase]]		[[Category: Deoxynucleoside kinase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
Line 41:		Line 29:
	[[Category: Salvage pathway]]		[[Category: Salvage pathway]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:19:04 2009''

OCA at 07:19, 17 February 2009

OCA — Tue, 17 Feb 2009 07:19:05 GMT

←Older revision		Revision as of 07:19, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2VQS is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA].	+	2VQS is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQS OCA].

	==Reference==		==Reference==
-	Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase., Mikkelsen NE, Munch-Petersen B, Eklund H, FEBS J. 2008 May;275(9):2151-60. Epub 2008 Apr 1. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18384378 18384378]~~	+	<ref group="xtra">PMID:18384378</ref><references group="xtra"/>
	[[Category: Deoxynucleoside kinase]]		[[Category: Deoxynucleoside kinase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
-	[[Category: Single protein]]
	[[Category: Eklund, H.]]		[[Category: Eklund, H.]]
	[[Category: Mikkelsen, N E.]]		[[Category: Mikkelsen, N E.]]
Line 43:		Line 42:
	[[Category: Transferase]]		[[Category: Transferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28 12:52~~:19 ~~2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:19:04 2009''