2vz1 - Revision history

OCA at 15:38, 13 December 2023

OCA — Wed, 13 Dec 2023 15:38:15 GMT

←Older revision		Revision as of 15:38, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2vz1' size='340' side='right'caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='2vz1' size='340' side='right'caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Fusairum_graminearum Fusairum~~ graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_graminearum Fusarium graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.91Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [https://pdbe.org/2vz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [https://pdbe.org/2vz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~GAOA_GIBZE GAOA_GIBZE]~~] Catalyzes the sterospecific oxidation of primary alcohols to the corresponding aldehydes. The biologically relevant substrate of the enzyme is not known as the enzyme exhibits broad substrate specificity from small alcohols through sugars to oligo- and polysaccharides ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/GAOA_GIBZA GAOA_GIBZA] Catalyzes the sterospecific oxidation of primary alcohols to the corresponding aldehydes. The biologically relevant substrate of the enzyme is not known as the enzyme exhibits broad substrate specificity from small alcohols through sugars to oligo- and polysaccharides.<ref>PMID:13641238</ref> <ref>PMID:4441089</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Fusairum~~ graminearum]]	+	[[Category: Fusarium graminearum]]
-	~~[[Category: Galactose oxidase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dooley~~, D M~~]]	+	[[Category: Dooley DM]]
-	[[Category: Firbank~~, S J~~]]	+	[[Category: Firbank SJ]]
-	[[Category: Halcrow~~, M A~~]]	+	[[Category: Halcrow MA]]
-	[[Category: Hurtado-Guerrero, R]]	+	[[Category: Hurtado-Guerrero R]]
-	[[Category: Knowles~~, P F~~]]	+	[[Category: Knowles PF]]
-	[[Category: McPherson~~, M J~~]]	+	[[Category: McPherson MJ]]
-	[[Category: Phillips~~, S E.V~~]]	+	[[Category: Phillips SEV]]
-	[[Category: Rogers~~, M S]]~~	+	[[Category: Rogers MS]]
-	~~[[Category: Anaerobic processing]]~~	+
-	~~[[Category: Copper]]~~	+
-	~~[[Category: Kelch repeat]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Secreted]]~~	+
-	~~[[Category: Thio-ether bond]]~~	+
-	~~[[Category: Thioether bond~~]]	+

OCA at 11:49, 30 March 2022

OCA — Wed, 30 Mar 2022 11:49:25 GMT

←Older revision		Revision as of 11:49, 30 March 2022
Line 3:		Line 3:
	<StructureSection load='2vz1' size='340' side='right'caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='2vz1' size='340' side='right'caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Fusairum_graminearum Fusairum graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusairum_graminearum Fusairum graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [~~http~~://pdbe.org/2vz1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [https://pdbe.org/2vz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GAOA_GIBZE GAOA_GIBZE]] Catalyzes the sterospecific oxidation of primary alcohols to the corresponding aldehydes. The biologically relevant substrate of the enzyme is not known as the enzyme exhibits broad substrate specificity from small alcohols through sugars to oligo- and polysaccharides (By similarity).	+	[[https://www.uniprot.org/uniprot/GAOA_GIBZE GAOA_GIBZE]] Catalyzes the sterospecific oxidation of primary alcohols to the corresponding aldehydes. The biologically relevant substrate of the enzyme is not known as the enzyme exhibits broad substrate specificity from small alcohols through sugars to oligo- and polysaccharides (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:42, 25 June 2020

OCA — Thu, 25 Jun 2020 08:42:50 GMT

←Older revision		Revision as of 08:42, 25 June 2020
Line 1:		Line 1:

	==Premat-galactose oxidase==		==Premat-galactose oxidase==
-	<StructureSection load='2vz1' size='340' side='right' caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>	+	<StructureSection load='2vz1' size='340' side='right'caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusairum_graminearum Fusairum graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusairum_graminearum Fusairum graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://pdbe.org/2vz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://pdbe.org/2vz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 39:		Line 39:
	[[Category: Fusairum graminearum]]		[[Category: Fusairum graminearum]]
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
		+	[[Category: Large Structures]]
	[[Category: Dooley, D M]]		[[Category: Dooley, D M]]
	[[Category: Firbank, S J]]		[[Category: Firbank, S J]]

OCA at 20:57, 19 September 2018

OCA — Wed, 19 Sep 2018 20:57:05 GMT

←Older revision		Revision as of 20:57, 19 September 2018
Line 1:		Line 1:
-	==~~PREMAT~~-~~GALACTOSE OXIDASE~~==	+
		+	==Premat-galactose oxidase==
	<StructureSection load='2vz1' size='340' side='right' caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='2vz1' size='340' side='right' caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Fusarium_graminearum Fusarium~~ graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusairum_graminearum Fusairum graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://pdbe.org/2vz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://pdbe.org/2vz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vz1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/2vz1_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/2vz1_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Fusarium~~ graminearum]]	+	[[Category: Fusairum graminearum]]
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
	[[Category: Dooley, D M]]		[[Category: Dooley, D M]]
Line 47:		Line 48:
	[[Category: Rogers, M S]]		[[Category: Rogers, M S]]
	[[Category: Anaerobic processing]]		[[Category: Anaerobic processing]]
		+	[[Category: Copper]]
	[[Category: Kelch repeat]]		[[Category: Kelch repeat]]
	[[Category: Metal-binding]]		[[Category: Metal-binding]]

OCA at 07:49, 8 February 2016

OCA — Mon, 08 Feb 2016 07:49:11 GMT

←Older revision		Revision as of 07:49, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2vz1' size='340' side='right' caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='2vz1' size='340' side='right' caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Gibberella_zeae Gibberella zeae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_graminearum Fusarium graminearum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://pdbe.org/2vz1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vz1 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2vz1" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Fusarium graminearum]]
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
-	[[Category: Gibberella zeae]]
	[[Category: Dooley, D M]]		[[Category: Dooley, D M]]
	[[Category: Firbank, S J]]		[[Category: Firbank, S J]]

OCA at 21:46, 24 December 2014

OCA — Wed, 24 Dec 2014 21:46:02 GMT

←Older revision		Revision as of 21:46, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GAOA_GIBZE GAOA_GIBZE]] Catalyzes the sterospecific oxidation of primary alcohols to the corresponding aldehydes. The biologically relevant substrate of the enzyme is not known as the enzyme exhibits broad substrate specificity from small alcohols through sugars to oligo- and polysaccharides (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
	[[Category: Gibberella zeae]]		[[Category: Gibberella zeae]]
-	[[Category: Dooley, D M.]]	+	[[Category: Dooley, D M]]
-	[[Category: Firbank, S J.]]	+	[[Category: Firbank, S J]]
-	[[Category: Halcrow, M A.]]	+	[[Category: Halcrow, M A]]
-	[[Category: Hurtado-Guerrero, R.]]	+	[[Category: Hurtado-Guerrero, R]]
-	[[Category: Knowles, P F.]]	+	[[Category: Knowles, P F]]
-	[[Category: McPherson, M J.]]	+	[[Category: McPherson, M J]]
-	[[Category: Phillips, S E.V.]]	+	[[Category: Phillips, S E.V]]
-	[[Category: Rogers, M S.]]	+	[[Category: Rogers, M S]]
	[[Category: Anaerobic processing]]		[[Category: Anaerobic processing]]
-	[[Category: Galactose oxidase]]
	[[Category: Kelch repeat]]		[[Category: Kelch repeat]]
	[[Category: Metal-binding]]		[[Category: Metal-binding]]

OCA at 09:58, 29 September 2014

OCA — Mon, 29 Sep 2014 09:58:22 GMT

←Older revision		Revision as of 09:58, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2vz1.~~png~~\|~~left~~\|200px]]	+	==PREMAT-GALACTOSE OXIDASE==
		+	<StructureSection load='2vz1' size='340' side='right' caption='[[2vz1]], [[Resolution\|resolution]] 1.91Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VZ1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1t2x\|1t2x]], [[1goh\|1goh]], [[1gof\|1gof]], [[1k3i\|1k3i]], [[1gog\|1gog]], [[2vz3\|2vz3]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Galactose_oxidase Galactose oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.9 1.1.3.9] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2vz1 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vz/2vz1_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Galactose oxidase (GO) belongs to a class of proteins that self-catalyze assembly of their redox-active cofactors from active site amino acids. Generation of enzymatically active GO appears to require at least four sequential post-translational modifications: cleavage of a secretion signal sequence, copper-dependent cleavage of an N-terminal pro sequence, copper-dependent formation of a C228-Y272 thioether bond, and generation of the Y272 radical. The last two processes were investigated using a truncated protein (termed premat-GO) lacking the pro sequence and purified under copper-free conditions. Reactions of premat-GO with Cu(II) were investigated using optical, EPR, and resonance Raman spectroscopy, SDS-PAGE, and X-ray crystallography. Premat-GO reacted anaerobically with excess Cu(II) to efficiently form the thioether bond but not the Y272 radical. A potential C228-copper coordinated intermediate (lambda max = 406 nm) in the processing reaction, which had not yet formed the C228-Y272 cross-link, was identified from the absorption spectrum. A copper-thiolate protein complex, with copper coordinated to C228, H496, and H581, was also observed in a 3 min anaerobic soak by X-ray crystallography, whereas a 24 h soak revealed the C228-Y272 thioether bond. In solution, addition of oxygenated buffer to premat-GO preincubated with excess Cu(II) generated the Y272 radical state. On the basis of these data, a mechanism for the formation of the C228-Y272 bond and tyrosyl radical generation is proposed. The 406 nm complex is demonstrated to be a catalytically competent processing intermediate under anaerobic conditions. We propose a potential mechanism which is in common with aerobic processing by Cu(II) until the step at which the second electron acceptor is required.

-	~~{{STRUCTURE_2vz1\| PDB=2vz1 \| SCENE= }}~~	+	Cross-link formation of the cysteine 228-tyrosine 272 catalytic cofactor of galactose oxidase does not require dioxygen.,Rogers MS, Hurtado-Guerrero R, Firbank SJ, Halcrow MA, Dooley DM, Phillips SE, Knowles PF, McPherson MJ Biochemistry. 2008 Sep 30;47(39):10428-39. Epub 2008 Sep 5. PMID:18771294<ref>PMID:18771294</ref>

-	~~===PREMAT-GALACTOSE OXIDASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18771294}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2vz1]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Gibberella_zeae Gibberella zeae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA].~~	+

	==See Also==		==See Also==
	*[[Galactose oxidase\|Galactose oxidase]]		*[[Galactose oxidase\|Galactose oxidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018771294<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
	[[Category: Gibberella zeae]]		[[Category: Gibberella zeae]]

OCA at 09:27, 20 October 2012

OCA — Sat, 20 Oct 2012 09:27:10 GMT

←Older revision		Revision as of 09:27, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2vz1]] is a 1 chain structure ~~of [[Galactose oxidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA].	+	[[2vz1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA].

	==See Also==		==See Also==

OCA: Protected "2vz1" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 22:53:23 GMT

Protected "2vz1" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:53, 25 July 2012

OCA at 22:53, 25 July 2012

OCA — Wed, 25 Jul 2012 22:53:21 GMT

←Older revision		Revision as of 22:53, 25 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2vz1.png\|left\|200px]]		[[Image:2vz1.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2vz1", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2vz1\| PDB=2vz1 \| SCENE= }}		{{STRUCTURE_2vz1\| PDB=2vz1 \| SCENE= }}

	===PREMAT-GALACTOSE OXIDASE===		===PREMAT-GALACTOSE OXIDASE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18771294}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18771294 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18771294}}		{{ABSTRACT_PUBMED_18771294}}

	==About this Structure==		==About this Structure==
-	~~2VZ1~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA].	+	[[2vz1]] is a 1 chain structure of [[Galactose oxidase]] with sequence from [http://en.wikipedia.org/wiki/Gibberella_zeae Gibberella zeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VZ1 OCA].
		+
		+	==See Also==
		+	*[[Galactose oxidase\|Galactose oxidase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18771294~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018771294</ref><references group="xtra"/>
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
	[[Category: Gibberella zeae]]		[[Category: Gibberella zeae]]
Line 35:		Line 26:
	[[Category: Rogers, M S.]]		[[Category: Rogers, M S.]]
	[[Category: Anaerobic processing]]		[[Category: Anaerobic processing]]
-	[[Category: Copper]]
	[[Category: Galactose oxidase]]		[[Category: Galactose oxidase]]
	[[Category: Kelch repeat]]		[[Category: Kelch repeat]]
Line 43:		Line 33:
	[[Category: Thio-ether bond]]		[[Category: Thio-ether bond]]
	[[Category: Thioether bond]]		[[Category: Thioether bond]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:19:33 2009''