2w0n - Revision history

OCA at 11:50, 30 March 2022

OCA — Wed, 30 Mar 2022 11:50:06 GMT

←Older revision		Revision as of 11:50, 30 March 2022
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	<StructureSection load='2w0n' size='340' side='right'caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2w0n' size='340' side='right'caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2W0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ojg\|1ojg]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [~~http~~://pdbe.org/2w0n PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [https://pdbe.org/2w0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [https://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.	+	[[https://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:45, 25 June 2020

OCA — Thu, 25 Jun 2020 08:45:15 GMT

←Older revision		Revision as of 08:45, 25 June 2020
Line 1:		Line 1:

	==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==		==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==
-	<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='2w0n' size='340' side='right'caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2W0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://pdbe.org/2w0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://pdbe.org/2w0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
		+	[[Category: Large Structures]]
	[[Category: Baldus, M]]		[[Category: Baldus, M]]
	[[Category: Becker, S]]		[[Category: Becker, S]]

OCA at 21:22, 19 September 2018

OCA — Wed, 19 Sep 2018 21:22:19 GMT

←Older revision		Revision as of 21:22, 19 September 2018
Line 1:		Line 1:
		+
	==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==		==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==
	<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://pdbe.org/2w0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://pdbe.org/2w0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w0n ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w0/2w0n_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w0/2w0n_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:36, 8 February 2016

OCA — Mon, 08 Feb 2016 01:36:29 GMT

←Older revision		Revision as of 01:36, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_bl21(de3) Escherichia~~ coli ~~bl21(de3)~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0N FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://pdbe.org/2w0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w0n ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2w0n" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Baldus, M]]		[[Category: Baldus, M]]

OCA at 19:35, 24 December 2014

OCA — Wed, 24 Dec 2014 19:35:49 GMT

←Older revision		Revision as of 19:35, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0N FirstGlance]. <br>		<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
-	[[Category: Baldus, M.]]	+	[[Category: Baldus, M]]
-	[[Category: Becker, S.]]	+	[[Category: Becker, S]]
-	[[Category: Duennwald, P.]]	+	[[Category: Duennwald, P]]
-	[[Category: Etzkorn, M.]]	+	[[Category: Etzkorn, M]]
-	[[Category: Griesinger, C.]]	+	[[Category: Griesinger, C]]
-	[[Category: Kneuper, H.]]	+	[[Category: Kneuper, H]]
-	[[Category: Kraemer, J.]]	+	[[Category: Kraemer, J]]
-	[[Category: Unden, G.]]	+	[[Category: Unden, G]]
-	[[Category: Vijayan, V.]]	+	[[Category: Vijayan, V]]
	[[Category: Cell inner membrane]]		[[Category: Cell inner membrane]]
	[[Category: Cell membrane]]		[[Category: Cell membrane]]

OCA at 04:27, 3 October 2014

OCA — Fri, 03 Oct 2014 04:27:07 GMT

←Older revision		Revision as of 04:27, 3 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2w0n\| PDB=2w0n \| SCENE= }}~~	+	==Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS==
-	===Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS===	+	<StructureSection load='2w0n' size='340' side='right' caption='[[2w0n]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
-	~~{{ABSTRACT_PUBMED_18820688}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W0N FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ojg\|1ojg]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w0n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w0n RCSB], [http://www.ebi.ac.uk/pdbsum/2w0n PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w0/2w0n_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The mechanistic understanding of how membrane-embedded sensor kinases recognize signals and regulate kinase activity is currently limited. Here we report structure-function relationships of the multidomain membrane sensor kinase DcuS using solid-state NMR, structural modeling and mutagenesis. Experimental data of an individual cytoplasmic Per-Arnt-Sim (PAS) domain were compared to structural models generated in silico. These studies, together with previous NMR work on the periplasmic PAS domain, enabled structural investigations of a membrane-embedded 40-kDa construct by solid-state NMR, comprising both PAS segments and the membrane domain. Structural alterations are largely limited to protein regions close to the transmembrane segment. Data from isolated and multidomain constructs favor a disordered N-terminal helix in the cytoplasmic domain. Mutations of residues in this region strongly influence function, suggesting that protein flexibility is related to signal transduction toward the kinase domain and regulation of kinase activity.

-	~~==Function==~~	+	Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS.,Etzkorn M, Kneuper H, Dunnwald P, Vijayan V, Kramer J, Griesinger C, Becker S, Unden G, Baldus M Nat Struct Mol Biol. 2008 Oct;15(10):1031-9. Epub 2008 Sep 28. PMID:18820688<ref>PMID:18820688</ref>
-	~~[[http://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member~~ of the ~~two-component regulatory system DcuR/~~DcuS. ~~Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system~~ (~~frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.~~)~~. Weakly regulates the aerobic C4~~-~~dicarboxylate transporter dctA~~. ~~Activates DcuR by phosphorylation~~.	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[2w0n]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:018820688</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Baldus, M.]]		[[Category: Baldus, M.]]

OCA at 11:34, 24 July 2013

OCA — Wed, 24 Jul 2013 11:34:49 GMT

←Older revision		Revision as of 11:34, 24 July 2013
Line 1:		Line 1:
-	[[Image:2w0n.png\|left\|200px]]
-
	{{STRUCTURE_2w0n\| PDB=2w0n \| SCENE= }}		{{STRUCTURE_2w0n\| PDB=2w0n \| SCENE= }}
		+	===Plasticity of PAS domain and potential role for signal transduction in the histidine-kinase DcuS===
		+	{{ABSTRACT_PUBMED_18820688}}

-	==~~=PLASTICITY OF PAS DOMAIN AND POTENTIAL ROLE FOR SIGNAL TRANSDUCTION IN THE HISTIDINE-KINASE DCUS=~~==	+	==Function==
-		+	[[http://www.uniprot.org/uniprot/DCUS_ECOLI DCUS_ECOLI]] Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation.
-	~~{{ABSTRACT_PUBMED_18820688}}~~	+

	==About this Structure==		==About this Structure==
-	[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli~~ Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].	+	[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21(de3) Escherichia coli bl21(de3)]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:018820688</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018820688</ref><references group="xtra"/><references/>
-	~~[[Category: Escherichia coli]]~~	+
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
	[[Category: Baldus, M.]]		[[Category: Baldus, M.]]

OCA: Protected "2w0n" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 20:28:08 GMT

Protected "2w0n" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:28, 7 January 2013

OCA at 20:28, 7 January 2013

OCA — Mon, 07 Jan 2013 20:28:04 GMT

←Older revision		Revision as of 20:28, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2w0n.png\|left\|200px]]		[[Image:2w0n.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2w0n", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2w0n\| PDB=2w0n \| SCENE= }}		{{STRUCTURE_2w0n\| PDB=2w0n \| SCENE= }}

	===PLASTICITY OF PAS DOMAIN AND POTENTIAL ROLE FOR SIGNAL TRANSDUCTION IN THE HISTIDINE-KINASE DCUS===		===PLASTICITY OF PAS DOMAIN AND POTENTIAL ROLE FOR SIGNAL TRANSDUCTION IN THE HISTIDINE-KINASE DCUS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18820688}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18820688 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_18820688}}		{{ABSTRACT_PUBMED_18820688}}

	==About this Structure==		==About this Structure==
-	~~2W0N~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].	+	[[2w0n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18820688~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018820688</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
Line 47:		Line 35:
	[[Category: Transmembrane]]		[[Category: Transmembrane]]
	[[Category: Two-component regulatory system]]		[[Category: Two-component regulatory system]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:51:56 2009''

OCA at 15:51, 16 February 2009

OCA — Mon, 16 Feb 2009 15:51:57 GMT

←Older revision		Revision as of 15:51, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2W0N is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].	+	2W0N is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W0N OCA].

	==Reference==		==Reference==
-	Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS., Etzkorn M, Kneuper H, Dunnwald P, Vijayan V, Kramer J, Griesinger C, Becker S, Unden G, Baldus M, Nat Struct Mol Biol. 2008 Oct;15(10):1031-9. Epub 2008 Sep 28. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18820688 18820688]~~	+	<ref group="xtra">PMID:18820688</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Histidine kinase]]		[[Category: Histidine kinase]]
-	[[Category: ~~Single protein~~]]	+	[[Category: Baldus, M.]]
-	[[Category: ~~Pdbx_ordinal=~~, ~~<PDBx~~:~~audit_author~~.]]	+	[[Category: Becker, S.]]
		+	[[Category: Duennwald, P.]]
		+	[[Category: Etzkorn, M.]]
		+	[[Category: Griesinger, C.]]
		+	[[Category: Kneuper, H.]]
		+	[[Category: Kraemer, J.]]
		+	[[Category: Unden, G.]]
		+	[[Category: Vijayan, V.]]
	[[Category: Cell inner membrane]]		[[Category: Cell inner membrane]]
	[[Category: Cell membrane]]		[[Category: Cell membrane]]
Line 41:		Line 48:
	[[Category: Two-component regulatory system]]		[[Category: Two-component regulatory system]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Dec 24 20~~:28:~~12 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:51:56 2009''