2w5f - Revision history

OCA at 10:08, 9 May 2024

OCA — Thu, 09 May 2024 10:08:24 GMT

←Older revision		Revision as of 10:08, 9 May 2024
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	<StructureSection load='2w5f' size='340' side='right'caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2w5f' size='340' side='right'caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"ruminiclostridium_thermocellum"_(viljoen_et_al._1926)_yutin_and_galperin_2013 "ruminiclostridium thermocellum" (viljoen et al. 1926) yutin and galperin 2013~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W5F FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]~~</~~div~~><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=PRD_900117:4beta-beta-xylotriose'>PRD_900117</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Endo~~-~~1,4~~-~~beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [https://pdbe.org/2w5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [https://www.ebi.ac.uk/pdbsum/2w5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5f ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [https://pdbe.org/2w5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [https://www.ebi.ac.uk/pdbsum/2w5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5f ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/XYNY_ACETH XYNY_ACETH]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Endo-1,4-beta-xylanase~~]]	+	[[Category: Acetivibrio thermocellus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fontes~~, C M.G A~~]]	+	[[Category: Fontes CMGA]]
-	[[Category: Najmudin, S]]	+	[[Category: Najmudin S]]
-	[[Category: Pinheiro~~, B A~~]]	+	[[Category: Pinheiro BA]]
-	[[Category: Prates~~, J A.M~~]]	+	[[Category: Prates JAM]]
-	[[Category: Romao~~, M J]]~~	+	[[Category: Romao MJ]]
-	~~[[Category: Cellulosome]]~~	+
-	~~[[Category: Glycosidase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Xylan degradation~~]]	+

OCA at 10:52, 7 July 2021

OCA — Wed, 07 Jul 2021 10:52:38 GMT

←Older revision		Revision as of 10:52, 7 July 2021
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	<StructureSection load='2w5f' size='340' side='right'caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2w5f' size='340' side='right'caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_(viljoen_et_al._1926)_yutin_and_galperin_2013 "ruminiclostridium thermocellum" (viljoen et al. 1926) yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2W5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_(viljoen_et_al._1926)_yutin_and_galperin_2013 "ruminiclostridium thermocellum" (viljoen et al. 1926) yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W5F FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [~~http~~://pdbe.org/2w5f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2w5f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5f ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [https://pdbe.org/2w5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [https://www.ebi.ac.uk/pdbsum/2w5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5f ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 12:17, 10 May 2019

OCA — Fri, 10 May 2019 12:17:44 GMT

←Older revision		Revision as of 12:17, 10 May 2019
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	==High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose==		==High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose==
-	<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2w5f' size='340' side='right'caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_yutin_and_galperin_2013 "ruminiclostridium thermocellum" yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_(viljoen_et_al._1926)_yutin_and_galperin_2013 "ruminiclostridium thermocellum" (viljoen et al. 1926) yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ruminiclostridium thermocellum yutin and galperin 2013]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
		+	[[Category: Large Structures]]
	[[Category: Fontes, C M.G A]]		[[Category: Fontes, C M.G A]]
	[[Category: Najmudin, S]]		[[Category: Najmudin, S]]

OCA at 08:58, 26 September 2018

OCA — Wed, 26 Sep 2018 08:58:49 GMT

←Older revision		Revision as of 08:58, 26 September 2018
Line 3:		Line 3:
	<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Atcc_27405 Atcc 27405~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"ruminiclostridium_thermocellum"_yutin_and_galperin_2013 "ruminiclostridium thermocellum" yutin and galperin 2013]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5f_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5f_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 27405~~]]	+	[[Category: Ruminiclostridium thermocellum yutin and galperin 2013]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Fontes, C M.G A]]		[[Category: Fontes, C M.G A]]

OCA at 07:17, 11 August 2016

OCA — Thu, 11 Aug 2016 07:17:45 GMT

←Older revision		Revision as of 07:17, 11 August 2016
Line 1:		Line 1:
		+
	==High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose==		==High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose==
	<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_thermocellum Clostridium thermocellum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_27405 Atcc 27405]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [http://www.ebi.ac.uk/pdbsum/2w5f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [http://pdbe.org/2w5f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [http://www.ebi.ac.uk/pdbsum/2w5f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w5f ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w5f ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2w5f" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Clostridium thermocellum~~]]	+	[[Category: Atcc 27405]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Fontes, C M.G A]]		[[Category: Fontes, C M.G A]]

OCA at 13:19, 19 January 2015

OCA — Mon, 19 Jan 2015 13:19:43 GMT

←Older revision		Revision as of 13:19, 19 January 2015
Line 32:		Line 32:
	[[Category: Clostridium thermocellum]]		[[Category: Clostridium thermocellum]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
-	[[Category: Fontes, C M.G A.]]	+	[[Category: Fontes, C M.G A]]
-	[[Category: Najmudin, S.]]	+	[[Category: Najmudin, S]]
-	[[Category: Pinheiro, B A.]]	+	[[Category: Pinheiro, B A]]
-	[[Category: Prates, J A.M.]]	+	[[Category: Prates, J A.M]]
-	[[Category: Romao, M J.]]	+	[[Category: Romao, M J]]
	[[Category: Cellulosome]]		[[Category: Cellulosome]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Xylan degradation]]		[[Category: Xylan degradation]]

OCA at 05:50, 10 October 2014

OCA — Fri, 10 Oct 2014 05:50:50 GMT

←Older revision		Revision as of 05:50, 10 October 2014
Line 2:		Line 2:
	<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. <br>	+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W5F FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [http://www.ebi.ac.uk/pdbsum/2w5f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [http://www.ebi.ac.uk/pdbsum/2w5f PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 24:
	Putting an N-terminal end to the Clostridium thermocellum xylanase Xyn10B story: Crystal structure of the CBM22-1-GH10 modules complexed with xylohexaose.,Najmudin S, Pinheiro BA, Prates JA, Gilbert HJ, Romao MJ, Fontes CM J Struct Biol. 2010 Aug 1. PMID:20682344<ref>PMID:20682344</ref>		Putting an N-terminal end to the Clostridium thermocellum xylanase Xyn10B story: Crystal structure of the CBM22-1-GH10 modules complexed with xylohexaose.,Najmudin S, Pinheiro BA, Prates JA, Gilbert HJ, Romao MJ, Fontes CM J Struct Biol. 2010 Aug 1. PMID:20682344<ref>PMID:20682344</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==

OCA at 08:35, 7 May 2014

OCA — Wed, 07 May 2014 08:35:06 GMT

←Older revision		Revision as of 08:35, 7 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2w5f.~~png~~\|~~left~~\|200px]]	+	==High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose==
		+	<StructureSection load='2w5f' size='340' side='right' caption='[[2w5f]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2w5f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dyo\|1dyo]], [[2ccl\|2ccl]], [[1h6x\|1h6x]], [[1wb6\|1wb6]], [[1ohz\|1ohz]], [[1h6y\|1h6y]], [[2wys\|2wys]], [[1gkl\|1gkl]], [[1wb5\|1wb5]], [[1gkk\|1gkk]], [[2wze\|2wze]], [[1wb4\|1wb4]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w5f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w5f RCSB], [http://www.ebi.ac.uk/pdbsum/2w5f PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/2w5f_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In general, plant cell wall degrading enzymes are modular proteins containing catalytic domains linked to one or more non-catalytic carbohydrate-binding modules (CBMs). Xyn10B from Clostridium thermocellum is a typical modular enzyme containing an N-terminal family 22 CBM (CBM22-1), a family 10 glycoside hydrolase catalytic domain (GH10), a second CBM22 (CBM22-2), a dockerin sequence and a C-terminal family 1 carbohydrate esterase (CE1) catalytic domain. The structure of the N-terminal bi-modular CBM22-1-GH10 component of Xyn10B has been determined using a SeMet derivative by SAD to 2.5A. The data was extended to 2.0A for the non-SeMet mutant complexed with xylohexaose. CBM22-1-GH10 is a 60kDa protein with an E337A mutation to render the GH10 subunit inactive. Three of the six xylose residues of xylohexaose are shown to be bound in the inactivated GH10 substrate binding cleft, with the other three sugars presumably disordered in the solvent channel. The protein is a dimer in the asymmetric unit with extensive surface contacts between the two GH10 modules and between the CBM22-1 and GH10 modules. Residues from helix H4 of the GH10 module provide the major contacts by fitting into the minor groove of the CBM22-1 module. The orientation of CBM22-1 is such that it would allow the substrate to be loosely bound and subsequently delivered to the active site in a processive manner.

-	<!--	+	Putting an N-terminal end to the Clostridium thermocellum xylanase Xyn10B story: Crystal structure of the CBM22-1-GH10 modules complexed with xylohexaose.,Najmudin S, Pinheiro BA, Prates JA, Gilbert HJ, Romao MJ, Fontes CM J Struct Biol. 2010 Aug 1. PMID:20682344<ref>PMID:20682344</ref>
-	~~The line below this paragraph, containing "STRUCTURE_2w5f", creates~~ the ~~"Structure Box" on~~ the ~~page~~.	+
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded)~~,	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2w5f\| PDB=2w5f \| SCENE= }}~~	+

-	~~===High resolution crystallographic structure~~ of the ~~Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20682344}}, adds the Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 20682344 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_20682344}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2w5f]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W5F OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020682344<~~/~~ref~~><~~ref group="xtra">PMID:018678939</ref><references group="xtra"~~/>	+
	[[Category: Clostridium thermocellum]]		[[Category: Clostridium thermocellum]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]

OCA at 09:56, 18 January 2012

OCA — Wed, 18 Jan 2012 09:56:22 GMT

←Older revision		Revision as of 09:56, 18 January 2012
Line 9:		Line 9:
	{{STRUCTURE_2w5f\| PDB=2w5f \| SCENE= }}		{{STRUCTURE_2w5f\| PDB=2w5f \| SCENE= }}

-	===~~HIGH RESOLUTION CRYSTALLOGRAPHIC STRUCTURE OF THE CLOSTRIDIUM THERMOCELLUM~~ N-~~TERMINAL ENDO~~-1,4-~~BETA~~-D-~~XYLANASE~~ 10B (~~XYN10B~~) CBM22-1-GH10 ~~MODULES COMPLEXED WITH XYLOHEXAOSE~~===	+	===High resolution crystallographic structure of the Clostridium thermocellum N-terminal endo-1,4-beta-D-xylanase 10B (Xyn10B) CBM22-1- GH10 modules complexed with xylohexaose===

OCA at 05:07, 24 August 2011

OCA — Wed, 24 Aug 2011 05:07:14 GMT

←Older revision		Revision as of 05:07, 24 August 2011
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20682344~~</ref><ref group="xtra">PMID:~~18678939~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020682344</ref><ref group="xtra">PMID:018678939</ref><references group="xtra"/>
	[[Category: Clostridium thermocellum]]		[[Category: Clostridium thermocellum]]
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]