2w7y - Revision history

OCA at 10:59, 6 April 2022

OCA — Wed, 06 Apr 2022 10:59:35 GMT

←Older revision		Revision as of 10:59, 6 April 2022
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	<StructureSection load='2w7y' size='340' side='right'caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='2w7y' size='340' side='right'caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL~~</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [~~http~~://pdbe.org/2w7y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2w7y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [https://pdbe.org/2w7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [https://www.ebi.ac.uk/pdbsum/2w7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:18, 1 July 2020

OCA — Wed, 01 Jul 2020 08:18:59 GMT

←Older revision		Revision as of 08:18, 1 July 2020
Line 1:		Line 1:

	==Structure of a Streptococcus pneumoniae solute-binding protein in complex with the blood group A-trisaccharide.==		==Structure of a Streptococcus pneumoniae solute-binding protein in complex with the blood group A-trisaccharide.==
-	<StructureSection load='2w7y' size='340' side='right' caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='2w7y' size='340' side='right'caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://pdbe.org/2w7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://pdbe.org/2w7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[ABC transporter\|ABC transporter]]	+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Streptococcus pneumoniae sp3-bs71]]		[[Category: Streptococcus pneumoniae sp3-bs71]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]

OCA at 08:55, 26 September 2018

OCA — Wed, 26 Sep 2018 08:55:11 GMT

←Older revision		Revision as of 08:55, 26 September 2018
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-	==~~STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE SOLUTE~~-~~BINDING PROTEIN IN COMPLEX WITH THE BLOOD GROUP~~ A-~~TRISACCHARIDE~~.==	+
		+	==Structure of a Streptococcus pneumoniae solute-binding protein in complex with the blood group A-trisaccharide.==
	<StructureSection load='2w7y' size='340' side='right' caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='2w7y' size='340' side='right' caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>,~~ <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://pdbe.org/2w7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://pdbe.org/2w7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7y_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7y_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 42:		Line 43:
	[[Category: Solute-binding protein]]		[[Category: Solute-binding protein]]
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
		+	[[Category: Sugar binding protein]]
	[[Category: Sugar-binding protein]]		[[Category: Sugar-binding protein]]

OCA at 18:16, 9 February 2016

OCA — Tue, 09 Feb 2016 18:16:50 GMT

←Older revision		Revision as of 18:16, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2w7y' size='340' side='right' caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='2w7y' size='340' side='right' caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pneumoniae~~ Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_sp3-bs71 Streptococcus pneumoniae sp3-bs71]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://pdbe.org/2w7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w7y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2w7y" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Streptococcus pneumoniae]]	+	[[Category: Streptococcus pneumoniae sp3-bs71]]
	[[Category: Abbott, D W]]		[[Category: Abbott, D W]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]
Line 40:		Line 41:
	[[Category: Carbohydrate transport]]		[[Category: Carbohydrate transport]]
	[[Category: Solute-binding protein]]		[[Category: Solute-binding protein]]
		+	[[Category: Streptococcus pneumoniae]]
	[[Category: Sugar-binding protein]]		[[Category: Sugar-binding protein]]

OCA at 17:19, 19 January 2015

OCA — Mon, 19 Jan 2015 17:19:14 GMT

←Older revision		Revision as of 17:19, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
-	[[Category: Abbott, D W.]]	+	[[Category: Abbott, D W]]
-	[[Category: Boraston, A B.]]	+	[[Category: Boraston, A B]]
-	[[Category: Boulanger, M J.]]	+	[[Category: Boulanger, M J]]
-	[[Category: Higgins, M A.]]	+	[[Category: Higgins, M A]]
	[[Category: Blood group antigen]]		[[Category: Blood group antigen]]
	[[Category: Carbohydrate transport]]		[[Category: Carbohydrate transport]]
	[[Category: Solute-binding protein]]		[[Category: Solute-binding protein]]
-	[[Category: Streptococcus pneumoniae]]
	[[Category: Sugar-binding protein]]		[[Category: Sugar-binding protein]]

OCA at 09:30, 29 September 2014

OCA — Mon, 29 Sep 2014 09:30:49 GMT

←Older revision		Revision as of 09:30, 29 September 2014
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-	[[~~Image:~~2w7y.~~png~~\|~~left~~\|200px]]	+	==STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE SOLUTE-BINDING PROTEIN IN COMPLEX WITH THE BLOOD GROUP A-TRISACCHARIDE.==
		+	<StructureSection load='2w7y' size='340' side='right' caption='[[2w7y]], [[Resolution\|resolution]] 2.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7Y FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7y RCSB], [http://www.ebi.ac.uk/pdbsum/2w7y PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/2w7y_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Streptococcus pneumoniae is a common bacterial pathogen that is well known for its ability to cause acute respiratory disease (pneumonia), ear infections, and other serious illnesses. This Gram-positive bacterium relies on its carbohydrate-metabolizing capabilities for full virulence in its host; however, the range of glycan targets that it can attack is presently not fully appreciated. S. pneumoniae is known to have a fucose utilization operon that in the TIGR4 strain plays a role in its virulence. Here we identify a second type of fucose utilization operon that is present in a subset of S. pneumoniae strains, including the serotype 3 strain SP3-BS71. This operon contains a transporter with a solute-binding protein, FcsSBP (fucose solute-binding protein), that interacts tightly (Ka approximately 1 x 10(6) M(-1)) and specifically with soluble A- and B-antigen trisaccharides but displays no selectivity between these two sugars. The structure of the FcsSBP in complex with the A-trisaccharide antigen, determined to 2.35 A, reveals its mode of binding to the reducing end of this sugar, thus highlighting this protein's requirement for soluble blood group antigen ligands. Overall, this report exposes a heretofore unknown capability of certain S. pneumoniae strains to transport and potentially metabolize the histo-blood group antigen carbohydrates of its host.

-	~~{{STRUCTURE_2w7y\| PDB=2w7y \| SCENE= }}~~	+	Blood group antigen recognition by a solute-binding protein from a serotype 3 strain of Streptococcus pneumoniae.,Higgins MA, Abbott DW, Boulanger MJ, Boraston AB J Mol Biol. 2009 May 1;388(2):299-309. Epub 2009 Mar 12. PMID:19285508<ref>PMID:19285508</ref>

-	~~===STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE SOLUTE-BINDING PROTEIN IN COMPLEX WITH THE BLOOD GROUP A-TRISACCHARIDE.===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19285508}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2w7y]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA].~~	+

	==See Also==		==See Also==
	*[[ABC transporter\|ABC transporter]]		*[[ABC transporter\|ABC transporter]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019285508<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
	[[Category: Abbott, D W.]]		[[Category: Abbott, D W.]]

OCA at 14:42, 20 October 2012

OCA — Sat, 20 Oct 2012 14:42:12 GMT

←Older revision		Revision as of 14:42, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2w7y]] is a 2 chain structure ~~of [[ABC transporter]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA].	+	[[2w7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA].

	==See Also==		==See Also==

OCA at 15:57, 26 July 2012

OCA — Thu, 26 Jul 2012 15:57:54 GMT

←Older revision		Revision as of 15:57, 26 July 2012
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	[[Image:2w7y.png\|left\|200px]]		[[Image:2w7y.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2w7y", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2w7y\| PDB=2w7y \| SCENE= }}		{{STRUCTURE_2w7y\| PDB=2w7y \| SCENE= }}

	===STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE SOLUTE-BINDING PROTEIN IN COMPLEX WITH THE BLOOD GROUP A-TRISACCHARIDE.===		===STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE SOLUTE-BINDING PROTEIN IN COMPLEX WITH THE BLOOD GROUP A-TRISACCHARIDE.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19285508}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19285508 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19285508}}		{{ABSTRACT_PUBMED_19285508}}

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	==See Also==		==See Also==
-	*[[ABC transporter]]	+	*[[ABC transporter\|ABC transporter]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19285508~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019285508</ref><references group="xtra"/>
	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
	[[Category: Abbott, D W.]]		[[Category: Abbott, D W.]]

OCA: Protected "2w7y" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 22:21:37 GMT

Protected "2w7y" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:21, 26 December 2010

OCA at 22:21, 26 December 2010

OCA — Sun, 26 Dec 2010 22:21:36 GMT

←Older revision		Revision as of 22:21, 26 December 2010
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-	{{Seed}}
	[[Image:2w7y.png\|left\|200px]]		[[Image:2w7y.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2W7Y~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA].	+	[[2w7y]] is a 2 chain structure of [[ABC transporter]] with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7Y OCA].
		+
		+	==See Also==
		+	*[[ABC transporter]]

	==Reference==		==Reference==
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	[[Category: Streptococcus pneumoniae]]		[[Category: Streptococcus pneumoniae]]
	[[Category: Sugar-binding protein]]		[[Category: Sugar-binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 29 20:34:17 2009''