2w9j - Revision history

OCA at 11:01, 6 April 2022

OCA — Wed, 06 Apr 2022 11:01:11 GMT

←Older revision		Revision as of 11:01, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2w9j' size='340' side='right'caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2w9j' size='340' side='right'caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2W9J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W9J FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [~~http~~://pdbe.org/2w9j PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2w9j PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [https://pdbe.org/2w9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [https://www.ebi.ac.uk/pdbsum/2w9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SRP14_SCHPO SRP14_SCHPO]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (By similarity).	+	[[https://www.uniprot.org/uniprot/SRP14_SCHPO SRP14_SCHPO]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:23, 1 July 2020

OCA — Wed, 01 Jul 2020 08:23:12 GMT

←Older revision		Revision as of 08:23, 1 July 2020
Line 1:		Line 1:

	==The crystal structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle==		==The crystal structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle==
-	<StructureSection load='2w9j' size='340' side='right' caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='2w9j' size='340' side='right'caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2W9J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W9J FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://pdbe.org/2w9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9j ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://pdbe.org/2w9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Cbs 356]]		[[Category: Cbs 356]]
		+	[[Category: Large Structures]]
	[[Category: Brooks, M A]]		[[Category: Brooks, M A]]
	[[Category: Cusack, S]]		[[Category: Cusack, S]]

OCA at 09:28, 26 September 2018

OCA — Wed, 26 Sep 2018 09:28:05 GMT

←Older revision		Revision as of 09:28, 26 September 2018
Line 1:		Line 1:
-	==~~THE CRYSTAL STRUCTURE OF~~ SRP14 ~~FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE~~==	+
		+	==The crystal structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle==
	<StructureSection load='2w9j' size='340' side='right' caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2w9j' size='340' side='right' caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>		<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://pdbe.org/2w9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://pdbe.org/2w9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w9j ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9j_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9j_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 37:		Line 38:
	[[Category: Brooks, M A]]		[[Category: Brooks, M A]]
	[[Category: Cusack, S]]		[[Category: Cusack, S]]
-	[[Category: ~~Mccarthy~~, A A]]	+	[[Category: McCarthy, A A]]
	[[Category: Ravelli, R B.G]]		[[Category: Ravelli, R B.G]]
	[[Category: Strub, K]]		[[Category: Strub, K]]

OCA at 20:51, 9 February 2016

OCA — Tue, 09 Feb 2016 20:51:52 GMT

←Older revision		Revision as of 20:51, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2w9j' size='340' side='right' caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2w9j' size='340' side='right' caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Schizosaccharomyces_pombe Schizosaccharomyces pombe~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://pdbe.org/2w9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w9j ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2w9j" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Schizosaccharomyces pombe~~]]	+	[[Category: Cbs 356]]
	[[Category: Brooks, M A]]		[[Category: Brooks, M A]]
	[[Category: Cusack, S]]		[[Category: Cusack, S]]
Line 45:		Line 46:
	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]
	[[Category: Rna-binding]]		[[Category: Rna-binding]]
		+	[[Category: Schizosaccharomyces pombe]]
	[[Category: Signal recognition particle]]		[[Category: Signal recognition particle]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 09:27, 25 December 2014

OCA — Thu, 25 Dec 2014 09:27:29 GMT

←Older revision		Revision as of 09:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>		<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SRP14_SCHPO SRP14_SCHPO]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
-	[[Category: Brooks, M A.]]	+	[[Category: Brooks, M A]]
-	[[Category: Cusack, S.]]	+	[[Category: Cusack, S]]
-	[[Category: Mccarthy, A A.]]	+	[[Category: Mccarthy, A A]]
-	[[Category: Ravelli, R B.G.]]	+	[[Category: Ravelli, R B.G]]
-	[[Category: Strub, K.]]	+	[[Category: Strub, K]]
	[[Category: Alu-domain]]		[[Category: Alu-domain]]
	[[Category: Arsenic]]		[[Category: Arsenic]]
Line 43:		Line 45:
	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]
	[[Category: Rna-binding]]		[[Category: Rna-binding]]
-	[[Category: Schizosaccharomyces pombe]]
	[[Category: Signal recognition particle]]		[[Category: Signal recognition particle]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 06:57, 29 September 2014

OCA — Mon, 29 Sep 2014 06:57:10 GMT

←Older revision		Revision as of 06:57, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2w9j.~~png\|left~~\|200px]]	+	==THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE==
		+	<StructureSection load='2w9j' size='340' side='right' caption='[[2w9j]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9J FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9j RCSB], [http://www.ebi.ac.uk/pdbsum/2w9j PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/2w9j_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The signal recognition particle (SRP) Alu domain has been implicated in translation elongation arrest in yeasts and mammals. Fission yeast SRP RNA is similar to that of mammals, but has a minimal Alu-domain RNA lacking two stem-loops. The mammalian Alu-domain proteins SRP9 and SRP14 bind their cognate Alu RNA as a heterodimer. However, in yeasts, notably Saccharomyces cerevisiae, SRP14 is thought to bind Alu RNA as a homodimer, the SRP9 protein being replaced by SRP21, the function of which is not yet clear. Structural characterization of the Schizosaccharomyces pombe Alu domain may thus help to identify the critical features required for elongation arrest. Here, the crystal structure of the SRP14 subunit of S. pombe SRP (SpSRP14) which crystallizes as a homodimer, is presented. Comparison of the SpSRP14 homodimer with the known structure of human SRP9/14 in complex with Alu RNA suggests that many of the protein-RNA contacts centred on the conserved U-turn motif are likely to be conserved in fission yeast. Initial attempts to solve the structure using traditional selenomethionine SAD labelling failed. However, two As atoms originating from the cacodylate buffer were found to make cysteine adducts and strongly contributed to the anomalous substructure. These adducts were highly radiation-sensitive and this property was exploited using the RIP (radiation-damage-induced phasing) method. The combination of SAD and RIP phases yielded an interpretable electron-density map. This example will be of general interest to crystallographers attempting de novo phasing from crystals grown in cacodylate buffer.

-	~~{{STRUCTURE_2w9j\| PDB=2w9j \| SCENE= }}~~	+	Structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle.,Brooks MA, Ravelli RB, McCarthy AA, Strub K, Cusack S Acta Crystallogr D Biol Crystallogr. 2009 May;65(Pt 5):421-33. Epub 2009, Apr 18. PMID:19390147<ref>PMID:19390147</ref>

-	~~===THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19390147}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2w9j]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].~~	+

	==See Also==		==See Also==
	*[[Signal recognition particle protein\|Signal recognition particle protein]]		*[[Signal recognition particle protein\|Signal recognition particle protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019390147<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: Brooks, M A.]]		[[Category: Brooks, M A.]]

OCA at 15:06, 20 October 2012

OCA — Sat, 20 Oct 2012 15:06:20 GMT

←Older revision		Revision as of 15:06, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2w9j]] is a 2 chain structure ~~of [[Signal recognition particle protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].	+	[[2w9j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].

	==See Also==		==See Also==

OCA: Protected "2w9j" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 17:18:09 GMT

Protected "2w9j" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:18, 26 July 2012

OCA at 17:18, 26 July 2012

OCA — Thu, 26 Jul 2012 17:18:06 GMT

←Older revision		Revision as of 17:18, 26 July 2012
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-	{{Seed}}
	[[Image:2w9j.png\|left\|200px]]		[[Image:2w9j.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2w9j", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2w9j\| PDB=2w9j \| SCENE= }}		{{STRUCTURE_2w9j\| PDB=2w9j \| SCENE= }}

	===THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE===		===THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19390147}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19390147 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19390147}}		{{ABSTRACT_PUBMED_19390147}}

	==About this Structure==		==About this Structure==
-	~~2W9J~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].	+	[[2w9j]] is a 2 chain structure of [[Signal recognition particle protein]] with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].
		+
		+	==See Also==
		+	*[[Signal recognition particle protein\|Signal recognition particle protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19390147~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019390147</ref><references group="xtra"/>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
	[[Category: Brooks, M A.]]		[[Category: Brooks, M A.]]
Line 33:		Line 24:
	[[Category: Arsenic]]		[[Category: Arsenic]]
	[[Category: Cacodylate]]		[[Category: Cacodylate]]
-	[[Category: Cytoplasm]]
	[[Category: Radiation-induced phasing]]		[[Category: Radiation-induced phasing]]
	[[Category: Ribonucleoprotein]]		[[Category: Ribonucleoprotein]]
Line 40:		Line 30:
	[[Category: Signal recognition particle]]		[[Category: Signal recognition particle]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:22:39 2009''

OCA at 06:22, 6 May 2009

OCA — Wed, 06 May 2009 06:22:39 GMT

←Older revision		Revision as of 06:22, 6 May 2009
Line 12:		Line 12:
	===THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE===		===THE CRYSTAL STRUCTURE OF SRP14 FROM THE SCHIZOSACCHAROMYCES POMBE SIGNAL RECOGNITION PARTICLE===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19390147}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19390147 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19390147}}

	==About this Structure==		==About this Structure==
-	2W9J is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].	+	2W9J is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9J OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19390147</ref><references group="xtra"/>
	[[Category: Schizosaccharomyces pombe]]		[[Category: Schizosaccharomyces pombe]]
-	[[Category: ~~Single protein~~]]	+	[[Category: Brooks, M A.]]
-	[[Category: ~~Pdbx_ordinal=~~, ~~<PDBx~~:~~audit_author~~.]]	+	[[Category: Cusack, S.]]
		+	[[Category: Mccarthy, A A.]]
		+	[[Category: Ravelli, R B.G.]]
		+	[[Category: Strub, K.]]
	[[Category: Alu-domain]]		[[Category: Alu-domain]]
	[[Category: Arsenic]]		[[Category: Arsenic]]
Line 29:		Line 41:
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Feb 16 20~~:05:45 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:22:39 2009''