2wfw - Revision history

OCA at 10:12, 9 May 2024

OCA — Thu, 09 May 2024 10:12:24 GMT

←Older revision		Revision as of 10:12, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='2wfw' size='340' side='right'caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wfw' size='340' side='right'caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium~~ erythropolis~~" gray and thornton 1928~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WFW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WFW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [https://pdbe.org/2wfw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [https://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [https://pdbe.org/2wfw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [https://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ARC_RHOER ARC_RHOER]] ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.[HAMAP-Rule:MF_02112]<ref>PMID:19481487</ref> <ref>PMID:9514743</ref>	+	[https://www.uniprot.org/uniprot/ARC_RHOER ARC_RHOER] ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.[HAMAP-Rule:MF_02112]<ref>PMID:19481487</ref> <ref>PMID:9514743</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Djuranovic, S]]	+	[[Category: Rhodococcus erythropolis]]
-	[[Category: Habeck, M]]	+	[[Category: Djuranovic S]]
-	[[Category: Hartmann~~, M D~~]]	+	[[Category: Habeck M]]
-	[[Category: Lupas~~, A N~~]]	+	[[Category: Hartmann MD]]
-	[[Category: Martin, J]]	+	[[Category: Lupas AN]]
-	[[Category: Ursinus, A]]	+	[[Category: Martin J]]
-	[[Category: Zeth, K]]	+	[[Category: Ursinus A]]
-	[[Category: Zwickl, P]]	+	[[Category: Zeth K]]
-	~~[[Category: Aaa]]~~	+	[[Category: Zwickl P]]
-	~~[[Category: Arc]]~~	+
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Atp-binding protein]]~~	+
-	~~[[Category: Nucleotide-binding]]~~	+
-	~~[[Category: Pan]]~~	+
-	~~[[Category: Proteasomal atpase~~]]	+

OCA at 11:06, 6 April 2022

OCA — Wed, 06 Apr 2022 11:06:27 GMT

←Older revision		Revision as of 11:06, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2wfw' size='340' side='right'caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wfw' size='340' side='right'caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WFW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WFW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [~~http~~://pdbe.org/2wfw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [https://pdbe.org/2wfw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [https://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ARC_RHOER ARC_RHOER]] ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.[HAMAP-Rule:MF_02112]<ref>PMID:19481487</ref> <ref>PMID:9514743</ref>	+	[[https://www.uniprot.org/uniprot/ARC_RHOER ARC_RHOER]] ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.[HAMAP-Rule:MF_02112]<ref>PMID:19481487</ref> <ref>PMID:9514743</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 2wfw" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2wfw" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ATPase 3D structures\|ATPase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:41, 1 July 2020

OCA — Wed, 01 Jul 2020 08:41:01 GMT

←Older revision		Revision as of 08:41, 1 July 2020
Line 1:		Line 1:

	==Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases - The Arc domain structure==		==Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases - The Arc domain structure==
-	<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='2wfw' size='340' side='right'caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WFW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WFW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://pdbe.org/2wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://pdbe.org/2wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium erythropolis gray and thornton 1928]]		[[Category: Mycobacterium erythropolis gray and thornton 1928]]
		+	[[Category: Large Structures]]
	[[Category: Djuranovic, S]]		[[Category: Djuranovic, S]]
	[[Category: Habeck, M]]		[[Category: Habeck, M]]

OCA at 08:51, 26 September 2018

OCA — Wed, 26 Sep 2018 08:51:38 GMT

←Older revision		Revision as of 08:51, 26 September 2018
Line 1:		Line 1:
-	==~~STRUCTURE AND ACTIVITY OF THE~~ N-~~TERMINAL SUBSTRATE RECOGNITION DOMAINS IN PROTEASOMAL ATPASES~~ - ~~THE ARC DOMAIN STRUCTURE~~==	+
		+	==Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases - The Arc domain structure==
	<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WFW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WFW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://pdbe.org/2wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://pdbe.org/2wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wfw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/2wfw_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/2wfw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:55, 7 February 2016

OCA — Sun, 07 Feb 2016 03:55:30 GMT

←Older revision		Revision as of 03:55, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rhodococcus_erythropolis Rhodococcus~~ erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WFW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WFW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://pdbe.org/2wfw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ARC_RHOER ARC_RHOER]] ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.[HAMAP-Rule:MF_02112]<ref>PMID:19481487</ref> <ref>PMID:9514743</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 13:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wfw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 23:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wfw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rhodococcus~~ erythropolis]]	+	[[Category: Mycobacterium erythropolis gray and thornton 1928]]
	[[Category: Djuranovic, S]]		[[Category: Djuranovic, S]]
	[[Category: Habeck, M]]		[[Category: Habeck, M]]

OCA at 08:50, 20 January 2015

OCA — Tue, 20 Jan 2015 08:50:30 GMT

←Older revision		Revision as of 08:50, 20 January 2015
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
-	[[Category: Djuranovic, S.]]	+	[[Category: Djuranovic, S]]
-	[[Category: Habeck, M.]]	+	[[Category: Habeck, M]]
-	[[Category: Hartmann, M D.]]	+	[[Category: Hartmann, M D]]
-	[[Category: Lupas, A N.]]	+	[[Category: Lupas, A N]]
-	[[Category: Martin, J.]]	+	[[Category: Martin, J]]
-	[[Category: Ursinus, A.]]	+	[[Category: Ursinus, A]]
-	[[Category: Zeth, K.]]	+	[[Category: Zeth, K]]
-	[[Category: Zwickl, P.]]	+	[[Category: Zwickl, P]]
	[[Category: Aaa]]		[[Category: Aaa]]
	[[Category: Arc]]		[[Category: Arc]]

OCA at 06:21, 10 October 2014

OCA — Fri, 10 Oct 2014 06:21:58 GMT

←Older revision		Revision as of 06:21, 10 October 2014
Line 2:		Line 2:
	<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. ~~<br>~~	+	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WFW FirstGlance]. <br>
-	~~</td></tr><tr><td class="sblockLbl">~~<b>~~Activity:~~</b>~~</td><td class="sblockDat"><span class='plainlinks'>~~[http://en.~~wikipedia~~.~~org~~/~~wiki/Glucokinase Glucokinase], with EC number [http://www.brenda~~-~~enzymes.info~~/~~php~~/~~result_flat~~.~~php4~~?~~ecno~~=~~2.7.1.2 2.7.1.2~~] <~~/span~~></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum]</span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 21:
	Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases.,Djuranovic S, Hartmann MD, Habeck M, Ursinus A, Zwickl P, Martin J, Lupas AN, Zeth K Mol Cell. 2009 Jun 12;34(5):580-90. Epub 2009 May 28. PMID:19481487<ref>PMID:19481487</ref>		Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases.,Djuranovic S, Hartmann MD, Habeck M, Ursinus A, Zwickl P, Martin J, Lupas AN, Zeth K Mol Cell. 2009 Jun 12;34(5):580-90. Epub 2009 May 28. PMID:19481487<ref>PMID:19481487</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==

OCA at 08:31, 7 May 2014

OCA — Wed, 07 May 2014 08:31:08 GMT

←Older revision		Revision as of 08:31, 7 May 2014
Line 1:		Line 1:
-	[[~~Image~~:2wfw.~~png\|left~~\|200px]]	+	==STRUCTURE AND ACTIVITY OF THE N-TERMINAL SUBSTRATE RECOGNITION DOMAINS IN PROTEASOMAL ATPASES - THE ARC DOMAIN STRUCTURE==
		+	<StructureSection load='2wfw' size='340' side='right' caption='[[2wfw]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wfw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wfw RCSB], [http://www.ebi.ac.uk/pdbsum/2wfw PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/2wfw_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The proteasome forms the core of the protein quality control system in archaea and eukaryotes and also occurs in one bacterial lineage, the Actinobacteria. Access to its proteolytic compartment is controlled by AAA ATPases, whose N-terminal domains (N domains) are thought to mediate substrate recognition. The N domains of an archaeal proteasomal ATPase, Archaeoglobus fulgidus PAN, and of its actinobacterial homolog, Rhodococcus erythropolis ARC, form hexameric rings, whose subunits consist of an N-terminal coiled coil and a C-terminal OB domain. In ARC-N, the OB domains are duplicated and form separate rings. PAN-N and ARC-N can act as chaperones, preventing the aggregation of heterologous proteins in vitro, and this activity is preserved in various chimeras, even when these include coiled coils and OB domains from unrelated proteins. The structures suggest a molecular mechanism for substrate processing based on concerted radial motions of the coiled coils relative to the OB rings.

-	<!--	+	Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases.,Djuranovic S, Hartmann MD, Habeck M, Ursinus A, Zwickl P, Martin J, Lupas AN, Zeth K Mol Cell. 2009 Jun 12;34(5):580-90. Epub 2009 May 28. PMID:19481487<ref>PMID:19481487</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2wfw"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2wfw\| PDB=2wfw \| SCENE= }}~~	+

-	~~===STRUCTURE AND ACTIVITY OF THE N-TERMINAL SUBSTRATE RECOGNITION DOMAINS IN PROTEASOMAL ATPASES - THE ARC DOMAIN STRUCTURE===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_19481487}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 19481487 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_19481487}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2wfw]] is a 3 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019481487<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
	[[Category: Djuranovic, S.]]		[[Category: Djuranovic, S.]]

OCA: Protected "2wfw" [edit=sysop:move=sysop]

OCA — Wed, 24 Aug 2011 04:55:22 GMT

Protected "2wfw" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:55, 24 August 2011

OCA at 04:55, 24 August 2011

OCA — Wed, 24 Aug 2011 04:55:21 GMT

←Older revision		Revision as of 04:55, 24 August 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2wfw.png\|left\|200px]]		[[Image:2wfw.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2WFW~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA].	+	[[2wfw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WFW OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19481487~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019481487</ref><references group="xtra"/>
	[[Category: Rhodococcus erythropolis]]		[[Category: Rhodococcus erythropolis]]
	[[Category: Djuranovic, S.]]		[[Category: Djuranovic, S.]]
Line 40:		Line 39:
	[[Category: Pan]]		[[Category: Pan]]
	[[Category: Proteasomal atpase]]		[[Category: Proteasomal atpase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 24 20:08:28 2009''