2wh9 - Revision history

OCA at 10:05, 14 June 2023

OCA — Wed, 14 Jun 2023 10:05:41 GMT

←Older revision		Revision as of 10:05, 14 June 2023
Line 1:		Line 1:

	==Solution structure of GxTX-1E==		==Solution structure of GxTX-1E==
-	<StructureSection load='2wh9' size='340' side='right'caption='[[2wh9~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2wh9' size='340' side='right'caption='[[2wh9]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chilobrachys_guangxiensis Chilobrachys guangxiensis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [https://pdbe.org/2wh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [https://pdbe.org/2wh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/TXG1E_CHIGU TXG1E_CHIGU]] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>	+	[https://www.uniprot.org/uniprot/TXG1E_CHIGU TXG1E_CHIGU] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chilobrachys guangxiensis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jung~~, H H~~]]	+	[[Category: Jung HH]]
-	[[Category: Kim~~, J I~~]]	+	[[Category: Kim JI]]
-	[[Category: Lee~~, C W~~]]	+	[[Category: Lee CW]]
-	[[Category: Lee~~, J Y~~]]	+	[[Category: Lee JY]]
-	[[Category: Lee~~, S K]]~~	+	[[Category: Lee SK]]
-	~~[[Category: Ionic channel inhibitor]]~~	+
-	~~[[Category: Knottin]]~~	+
-	~~[[Category: Membrane protein inhibitor]]~~	+
-	~~[[Category: Potassium channel inhibitor~~]]	+

OCA at 05:24, 10 August 2022

OCA — Wed, 10 Aug 2022 05:24:11 GMT

←Older revision		Revision as of 05:24, 10 August 2022
Line 3:		Line 3:
	<StructureSection load='2wh9' size='340' side='right'caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2wh9' size='340' side='right'caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [~~http~~://pdbe.org/2wh9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [https://pdbe.org/2wh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/TXG1E_CHIGU TXG1E_CHIGU]] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>	+	[[https://www.uniprot.org/uniprot/TXG1E_CHIGU TXG1E_CHIGU]] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:59, 4 November 2020

OCA — Wed, 04 Nov 2020 07:59:35 GMT

←Older revision		Revision as of 07:59, 4 November 2020
Line 1:		Line 1:

	==Solution structure of GxTX-1E==		==Solution structure of GxTX-1E==
-	<StructureSection load='2wh9' size='340' side='right' caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2wh9' size='340' side='right'caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://pdbe.org/2wh9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://pdbe.org/2wh9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Jung, H H]]		[[Category: Jung, H H]]
	[[Category: Kim, J I]]		[[Category: Kim, J I]]

OCA at 06:19, 19 April 2017

OCA — Wed, 19 Apr 2017 06:19:47 GMT

←Older revision		Revision as of 06:19, 19 April 2017
Line 1:		Line 1:

-	==~~SOLUTION STRUCTURE OF GXTX~~-1E==	+	==Solution structure of GxTX-1E==
	<StructureSection load='2wh9' size='340' side='right' caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2wh9' size='340' side='right' caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 17:42, 4 August 2016

OCA — Thu, 04 Aug 2016 17:42:43 GMT

←Older revision		Revision as of 17:42, 4 August 2016
Line 1:		Line 1:
		+
	==SOLUTION STRUCTURE OF GXTX-1E==		==SOLUTION STRUCTURE OF GXTX-1E==
	<StructureSection load='2wh9' size='340' side='right' caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2wh9' size='340' side='right' caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://pdbe.org/2wh9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~TXG1E_CHIJI TXG1E_CHIJI~~]] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>	+	[[http://www.uniprot.org/uniprot/TXG1E_CHIGU TXG1E_CHIGU]] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wh9" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:31, 25 December 2014

OCA — Thu, 25 Dec 2014 11:31:27 GMT

←Older revision		Revision as of 11:31, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TXG1E_CHIJI TXG1E_CHIJI]] Gating modifier of Kv2.1/KCNB1 (IC(50)=5.1 nM), Kv2.2/KCNB2 and Kv4.3/KCND3 channels (IC(50)=39 nM). Acts by shifting the channel activation to more depolarized potentials by stabilizing the resting conformation of the voltage sensor. It completely inhibits opening of the Kv2.1/KCNB1 channel at negative membrane voltages and dramatically shifts channel activation to positive voltages. May act by partitioning into lipid membranes and then by binding the voltage sensor paddle of the channel from a place within the membrane.<ref>PMID:16567526</ref> <ref>PMID:17101164</ref> <ref>PMID:21150283</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Jung, H H.]]	+	[[Category: Jung, H H]]
-	[[Category: Kim, J I.]]	+	[[Category: Kim, J I]]
-	[[Category: Lee, C W.]]	+	[[Category: Lee, C W]]
-	[[Category: Lee, J Y.]]	+	[[Category: Lee, J Y]]
-	[[Category: Lee, S K.]]	+	[[Category: Lee, S K]]
	[[Category: Ionic channel inhibitor]]		[[Category: Ionic channel inhibitor]]
	[[Category: Knottin]]		[[Category: Knottin]]
	[[Category: Membrane protein inhibitor]]		[[Category: Membrane protein inhibitor]]
	[[Category: Potassium channel inhibitor]]		[[Category: Potassium channel inhibitor]]

OCA at 11:27, 20 October 2014

OCA — Mon, 20 Oct 2014 11:27:11 GMT

←Older revision		Revision as of 11:27, 20 October 2014
Line 1:		Line 1:
-	[[~~Image~~:2wh9.~~png\|left\|200px~~]]	+	==SOLUTION STRUCTURE OF GXTX-1E==
		+	<StructureSection load='2wh9' size='340' side='right' caption='[[2wh9]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WH9 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wh9 RCSB], [http://www.ebi.ac.uk/pdbsum/2wh9 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	GxTX-1E is a neurotoxin recently isolated from Plesiophrictus guangxiensis venom that inhibits the Kv2.1 channel in pancreatic beta-cells. The sequence of the toxin is related to those of previously studied tarantula toxins that interact with the voltage sensors in Kv channels, and GxTX-1E interacts with the Kv2.1 channel with unusually high affinity, making it particularly useful for structural and mechanistic studies. Here we determined the three-dimensional solution structure of GxTX-1E using NMR spectroscopy and compared it to that of several related tarantula toxins. The molecular structure of GxTX-1E is similar to those of tarantula toxins that target voltage sensors in Kv channels in that it contains an ICK motif, composed of beta-strands, and contains a prominent cluster of solvent-exposed hydrophobic residues surrounded by polar residues. When compared with the structure of SGTx1, a toxin for which mutagenesis data are available, the residue compositions of the two toxins are distinct in regions that are critical for activity, suggesting that their modes of binding to voltage sensors may be different. Interestingly, the structural architecture of GxTX-1E is also similar to that of JZTX-III, a tarantula toxin that interacts with Kv2.1 with low affinity. The most striking structural differences between GxTX-1E and JZTX-III are found in the orientation between the first and second cysteine loops and the C-terminal region of the toxins, suggesting that these regions of GxTX-1E are responsible for its high affinity.

-	~~{{STRUCTURE_2wh9\| PDB=2wh9 \| SCENE= }}~~	+	Solution Structure of GxTX-1E, a High-Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels .,Lee S, Milescu M, Jung HH, Lee JY, Bae CH, Lee CW, Kim HH, Swartz KJ, Kim JI Biochemistry. 2010 Jun 7. PMID:20509680<ref>PMID:20509680</ref>

-	~~===SOLUTION STRUCTURE OF GXTX-1E===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20509680}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wh9]] is~~ a ~~1 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2WH9 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020509680<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Jung, H H.]]		[[Category: Jung, H H.]]
	[[Category: Kim, J I.]]		[[Category: Kim, J I.]]

OCA at 18:19, 7 January 2013

OCA — Mon, 07 Jan 2013 18:19:05 GMT

←Older revision		Revision as of 18:19, 7 January 2013
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	[[Image:2wh9.png\|left\|200px]]		[[Image:2wh9.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2wh9\| PDB=2wh9 \| SCENE= }}		{{STRUCTURE_2wh9\| PDB=2wh9 \| SCENE= }}

	===SOLUTION STRUCTURE OF GXTX-1E===		===SOLUTION STRUCTURE OF GXTX-1E===

-
-	<!--
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	{{ABSTRACT_PUBMED_20509680}}		{{ABSTRACT_PUBMED_20509680}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20509680~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020509680</ref><references group="xtra"/>
	[[Category: Jung, H H.]]		[[Category: Jung, H H.]]
	[[Category: Kim, J I.]]		[[Category: Kim, J I.]]

OCA: Protected "2wh9" [edit=sysop:move=sysop]

OCA — Wed, 29 Dec 2010 18:28:27 GMT

Protected "2wh9" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:28, 29 December 2010

OCA at 18:28, 29 December 2010

OCA — Wed, 29 Dec 2010 18:28:24 GMT

←Older revision		Revision as of 18:28, 29 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2wh9.png\|left\|200px]]		[[Image:2wh9.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2WH9~~ is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA].	+	[[2wh9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH9 OCA].

	==Reference==		==Reference==
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	[[Category: Membrane protein inhibitor]]		[[Category: Membrane protein inhibitor]]
	[[Category: Potassium channel inhibitor]]		[[Category: Potassium channel inhibitor]]
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-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:49:45 2010''