2wjp - Revision history

OCA at 15:59, 13 December 2023

OCA — Wed, 13 Dec 2023 15:59:23 GMT

←Older revision		Revision as of 15:59, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Escherichia_coli_dh5[alpha]~~ Escherichia coli ~~dh5[alpha]~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH5alpha Escherichia coli DH5alpha]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vtd\|2vtd]]~~, ~~[[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]~~<~~/div></td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[https://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [https://pdbe.org/2wjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [https://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [https://pdbe.org/2wjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [https://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]	+	[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 39:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]~~	+	[[Category: Blanot D]]
-	[[Category: Blanot, D]]	+	[[Category: Contreras-Martel C]]
-	[[Category: Contreras-Martel, C]]	+	[[Category: Dessen A]]
-	[[Category: Dessen, A]]	+	[[Category: Gobec S]]
-	[[Category: Gobec, S]]	+	[[Category: Kikelj D]]
-	[[Category: Kikelj, D]]	+	[[Category: Kovac A]]
-	[[Category: Kovac, A]]	+	[[Category: Muller-Premru M]]
-	[[Category: Muller-Premru, M]]	+	[[Category: Peterlin-Masic L]]
-	[[Category: Peterlin-Masic, L]]	+	[[Category: Rupnik V]]
-	[[Category: Rupnik, V]]	+	[[Category: Sink R]]
-	[[Category: Sink, R]]	+	[[Category: Tomasic T]]
-	[[Category: Tomasic, T]]	+	[[Category: Turk S]]
-	[[Category: Turk, S]]	+	[[Category: Zega A]]
-	[[Category: Zega, A]]	+	[[Category: Zidar N]]
-	[[Category: Zidar, N]]	+
-	~~[[Category: Cell cycle]]~~	+
-	~~[[Category: Cell division]]~~	+
-	~~[[Category: Cell shape synthesis]]~~	+
-	~~[[Category: Cell wall biogenesis/degradation]]~~	+
-	~~[[Category: Ligase]]~~	+
-	~~[[Category: Peptidoglycan synthesis~~]]	+

OCA at 11:09, 6 April 2022

OCA — Wed, 06 Apr 2022 11:09:07 GMT

OCA at 08:49, 1 July 2020

OCA — Wed, 01 Jul 2020 08:49:15 GMT

←Older revision		Revision as of 08:49, 1 July 2020
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR==		==CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR==
-	<StructureSection load='2wjp' size='340' side='right' caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [http://pdbe.org/2wjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [http://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [http://pdbe.org/2wjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [http://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 38:		Line 38:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]		[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
	[[Category: Blanot, D]]		[[Category: Blanot, D]]

OCA at 09:26, 26 September 2018

OCA — Wed, 26 Sep 2018 09:26:33 GMT

←Older revision		Revision as of 09:26, 26 September 2018
Line 16:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wjp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wjp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:

	==See Also==		==See Also==
-	*[[~~MurD~~ ligase\|~~MurD~~ ligase]]	+	*[[Mur ligase\|Mur ligase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:47, 4 August 2016

OCA — Thu, 04 Aug 2016 12:47:55 GMT

←Older revision		Revision as of 12:47, 4 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR==		==CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR==
	<StructureSection load='2wjp' size='340' side='right' caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wjp' size='340' side='right' caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [http://www.ebi.ac.uk/pdbsum/2wjp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [http://pdbe.org/2wjp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [http://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wjp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 29:		Line 30:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wjp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 38:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus coli migula 1895]]
	[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]		[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
	[[Category: Blanot, D]]		[[Category: Blanot, D]]

OCA at 09:26, 25 December 2014

OCA — Thu, 25 Dec 2014 09:26:40 GMT

←Older revision		Revision as of 09:26, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2wjp\| PDB=2wjp \| SCENE= }}~~	+	==CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR==
-	===CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR===	+	<StructureSection load='2wjp' size='340' side='right' caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>
-	{{~~ABSTRACT_PUBMED_20804196~~}}	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [http://www.ebi.ac.uk/pdbsum/2wjp PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]		[[http://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/2wjp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have designed, synthesized, and evaluated 5-benzylidenerhodanine- and 5-benzylidenethiazolidine-2,4-dione-based compounds as inhibitors of bacterial enzyme MurD with E. coli IC(50) in the range 45-206 muM. The high-resolution crystal structure of MurD in complex with (R,Z)-2-(3-[{4-([2,4-dioxothiazolidin-5-ylidene]methyl)phenylamino}methyl) benzamido)pentanedioic acid [(R)-32] revealed details of the binding mode of the inhibitor within the active site and provides a good foundation for structure-based design of a novel generation of MurD inhibitors.

-	~~==About this Structure==~~	+	Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase.,Zidar N, Tomasic T, Sink R, Rupnik V, Kovac A, Turk S, Patin D, Blanot D, Contreras Martel C, Dessen A, Muller Premru M, Zega A, Gobec S, Peterlin Masic L, Kikelj D J Med Chem. 2010 Aug 30. PMID:20804196<ref>PMID:20804196</ref>
-	~~[[2wjp]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2WJP OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[MurD ligase\|MurD ligase]]		*[[MurD ligase\|MurD ligase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:020804196</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]		[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
-	[[Category: Blanot, D.]]	+	[[Category: Blanot, D]]
-	[[Category: Contreras-Martel, C.]]	+	[[Category: Contreras-Martel, C]]
-	[[Category: Dessen, A.]]	+	[[Category: Dessen, A]]
-	[[Category: Gobec, S.]]	+	[[Category: Gobec, S]]
-	[[Category: Kikelj, D.]]	+	[[Category: Kikelj, D]]
-	[[Category: Kovac, A.]]	+	[[Category: Kovac, A]]
-	[[Category: Muller-Premru, M.]]	+	[[Category: Muller-Premru, M]]
-	[[Category: Peterlin-Masic, L.]]	+	[[Category: Peterlin-Masic, L]]
-	[[Category: Rupnik, V.]]	+	[[Category: Rupnik, V]]
-	[[Category: Sink, R.]]	+	[[Category: Sink, R]]
-	[[Category: Tomasic, T.]]	+	[[Category: Tomasic, T]]
-	[[Category: Turk, S.]]	+	[[Category: Turk, S]]
-	[[Category: Zega, A.]]	+	[[Category: Zega, A]]
-	[[Category: Zidar, N.]]	+	[[Category: Zidar, N]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]
	[[Category: Cell division]]		[[Category: Cell division]]

OCA at 14:38, 3 March 2014

OCA — Mon, 03 Mar 2014 14:38:11 GMT

←Older revision		Revision as of 14:38, 3 March 2014
Line 1:		Line 1:
-	[[Image:2wjp.png\|left\|200px]]
-
	{{STRUCTURE_2wjp\| PDB=2wjp \| SCENE= }}		{{STRUCTURE_2wjp\| PDB=2wjp \| SCENE= }}
-
	===CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR===		===CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR===
		+	{{ABSTRACT_PUBMED_20804196}}

		+	==Function==
		+	[[http://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]

	==About this Structure==		==About this Structure==
-	[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA].	+	[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA].
-	[[Category: ~~Escherichia~~ coli]]	+
		+	==See Also==
		+	*[[MurD ligase\|MurD ligase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:020804196</ref><references group="xtra"/><references/>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]		[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
	[[Category: Blanot, D.]]		[[Category: Blanot, D.]]

OCA: Protected "2wjp" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 20:57:33 GMT

Protected "2wjp" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:57, 7 January 2013

OCA at 20:57, 7 January 2013

OCA — Mon, 07 Jan 2013 20:57:29 GMT

←Older revision		Revision as of 20:57, 7 January 2013
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:2wjp.png\|left\|200px]]
-	[[Image:2wjp.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2wjp", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2wjp\| PDB=2wjp \| SCENE= }}		{{STRUCTURE_2wjp\| PDB=2wjp \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~2WJP~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA].	+	[[2wjp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA].
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]		[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
Line 37:		Line 30:
	[[Category: Ligase]]		[[Category: Ligase]]
	[[Category: Peptidoglycan synthesis]]		[[Category: Peptidoglycan synthesis]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:48:32 2010''

OCA at 04:40, 25 August 2010

OCA — Wed, 25 Aug 2010 04:40:45 GMT

←Older revision		Revision as of 04:40, 25 August 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2wjp.jpg\|left\|200px]]

-	The ~~entry 2wjp~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2wjp", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2wjp\| PDB=2wjp \| SCENE= }}

-	~~Authors: Tomasic, T., Zidar, N., Sink, R., Kovac, A., Rupnik, V., Turk, S., Contreras-Martel, C., Dessen, A., Blanot,~~ D~~., Muller~~-~~Premru, M., Gobec, S., Zega, A., Peterlin-Masic, L., Kikelj, D.~~	+	===CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR===

-	Description: CRYSTAL STRUCTURE OF MURD LIGASE IN COMPLEX WITH D-GLU CONTAINING RHODANINE INHIBITOR

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 16~~ 08:26:19 2010''	+	==About this Structure==
		+	2WJP is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase]]
		+	[[Category: Blanot, D.]]
		+	[[Category: Contreras-Martel, C.]]
		+	[[Category: Dessen, A.]]
		+	[[Category: Gobec, S.]]
		+	[[Category: Kikelj, D.]]
		+	[[Category: Kovac, A.]]
		+	[[Category: Muller-Premru, M.]]
		+	[[Category: Peterlin-Masic, L.]]
		+	[[Category: Rupnik, V.]]
		+	[[Category: Sink, R.]]
		+	[[Category: Tomasic, T.]]
		+	[[Category: Turk, S.]]
		+	[[Category: Zega, A.]]
		+	[[Category: Zidar, N.]]
		+	[[Category: Cell cycle]]
		+	[[Category: Cell division]]
		+	[[Category: Cell shape synthesis]]
		+	[[Category: Cell wall biogenesis/degradation]]
		+	[[Category: Ligase]]
		+	[[Category: Peptidoglycan synthesis]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:48:32 2010''

←Older revision		Revision as of 11:09, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2wjp' size='340' side='right'caption='[[2wjp]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wjp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_dh5[alpha] Escherichia coli dh5[alpha]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WJP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WJP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=D17:N-({3-[({4-[(Z)-(4-OXO-2-THIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]PHENYL}AMINO)METHYL]PHENYL}CARBONYL)-L-GLUTAMIC+ACID'>D17</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vtd\|2vtd]], [[2uuo\|2uuo]], [[2jfg\|2jfg]], [[1uag\|1uag]], [[4uag\|4uag]], [[2uag\|2uag]], [[2jfh\|2jfh]], [[3uag\|3uag]], [[2uup\|2uup]], [[1e0d\|1e0d]], [[2vte\|2vte]], [[2jff\|2jff]], [[1eeh\|1eeh]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-L-alanine--D-glutamate_ligase UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.9 6.3.2.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [~~http~~://pdbe.org/2wjp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wjp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wjp OCA], [https://pdbe.org/2wjp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wjp RCSB], [https://www.ebi.ac.uk/pdbsum/2wjp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wjp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]	+	[[https://www.uniprot.org/uniprot/MURD_ECOLI MURD_ECOLI]] Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).[HAMAP-Rule:MF_00639]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]