2wlu - Revision history

OCA at 10:13, 9 May 2024

OCA — Thu, 09 May 2024 10:13:58 GMT

←Older revision		Revision as of 10:13, 9 May 2024
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	<StructureSection load='2wlu' size='340' side='right'caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2wlu' size='340' side='right'caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.94Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [https://pdbe.org/2wlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [https://www.ebi.ac.uk/pdbsum/2wlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [https://pdbe.org/2wlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [https://www.ebi.ac.uk/pdbsum/2wlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q99YU7_STRP1 Q99YU7_STRP1]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Micrococcus scarlatinae klein 1884]]
-	[[Category: Ferroxidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Haikarainen, T]]	+	[[Category: Streptococcus pyogenes]]
-	[[Category: Papageorgiou~~, A C~~]]	+	[[Category: Haikarainen T]]
-	[[Category: Tsou, C C]]	+	[[Category: Papageorgiou AC]]
-	[[Category: Wu, J J]]	+	[[Category: Tsou C-C]]
-	~~[[Category: Dna-binding]]~~	+	[[Category: Wu J-J]]
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 10:56, 7 July 2021

OCA — Wed, 07 Jul 2021 10:56:01 GMT

←Older revision		Revision as of 10:56, 7 July 2021
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	<StructureSection load='2wlu' size='340' side='right'caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2wlu' size='340' side='right'caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WLU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WLU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [~~http~~://pdbe.org/2wlu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wlu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [https://pdbe.org/2wlu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [https://www.ebi.ac.uk/pdbsum/2wlu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlu ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:44, 24 July 2019

OCA — Wed, 24 Jul 2019 07:44:20 GMT

←Older revision		Revision as of 07:44, 24 July 2019
Line 1:		Line 1:

	==Iron-bound crystal structure of Streptococcus pyogenes Dpr==		==Iron-bound crystal structure of Streptococcus pyogenes Dpr==
-	<StructureSection load='2wlu' size='340' side='right' caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>	+	<StructureSection load='2wlu' size='340' side='right'caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>
Line 33:		Line 33:
	[[Category: Micrococcus scarlatinae klein 1884]]		[[Category: Micrococcus scarlatinae klein 1884]]
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
		+	[[Category: Large Structures]]
	[[Category: Haikarainen, T]]		[[Category: Haikarainen, T]]
	[[Category: Papageorgiou, A C]]		[[Category: Papageorgiou, A C]]

OCA at 09:02, 26 September 2018

OCA — Wed, 26 Sep 2018 09:02:10 GMT

←Older revision		Revision as of 09:02, 26 September 2018
Line 1:		Line 1:
-	==~~IRON~~-~~BOUND CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES DPR~~==	+
		+	==Iron-bound crystal structure of Streptococcus pyogenes Dpr==
	<StructureSection load='2wlu' size='340' side='right' caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2wlu' size='340' side='right' caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://pdbe.org/2wlu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://pdbe.org/2wlu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wlu ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlu_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlu_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 18:14, 7 February 2016

OCA — Sun, 07 Feb 2016 18:14:01 GMT

←Older revision		Revision as of 18:14, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2wlu' size='340' side='right' caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='2wlu' size='340' side='right' caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_pyogenes Streptococcus pyogenes~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://pdbe.org/2wlu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wlu ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wlu" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Micrococcus scarlatinae klein 1884]]
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
-	[[Category: Streptococcus pyogenes]]
	[[Category: Haikarainen, T]]		[[Category: Haikarainen, T]]
	[[Category: Papageorgiou, A C]]		[[Category: Papageorgiou, A C]]

OCA at 07:50, 20 January 2015

OCA — Tue, 20 Jan 2015 07:50:05 GMT

←Older revision		Revision as of 07:50, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
	[[Category: Streptococcus pyogenes]]		[[Category: Streptococcus pyogenes]]
-	[[Category: Haikarainen, T.]]	+	[[Category: Haikarainen, T]]
-	[[Category: Papageorgiou, A C.]]	+	[[Category: Papageorgiou, A C]]
-	[[Category: Tsou, C C.]]	+	[[Category: Tsou, C C]]
-	[[Category: Wu, J J.]]	+	[[Category: Wu, J J]]
	[[Category: Dna-binding]]		[[Category: Dna-binding]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 01:17, 1 October 2014

OCA — Wed, 01 Oct 2014 01:17:41 GMT

←Older revision		Revision as of 01:17, 1 October 2014
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-	[[~~Image~~:2wlu.~~png\|left~~\|200px]]	+	==IRON-BOUND CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES DPR==
		+	<StructureSection load='2wlu' size='340' side='right' caption='[[2wlu]], [[Resolution\|resolution]] 1.94Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WLU FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferroxidase Ferroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.16.3.1 1.16.3.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wlu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wlu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wlu RCSB], [http://www.ebi.ac.uk/pdbsum/2wlu PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/2wlu_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DNA-binding protein from starved cells (Dps)-like proteins are key factors involved in oxidative stress protection in bacteria. They bind and oxidize iron, thus preventing the formation of harmful reactive oxygen species that can damage biomolecules, particularly DNA. Dps-like proteins are composed of 12 identical subunits assembled in a spherical structure with a hollow central cavity. The iron oxidation occurs at 12 intersubunit sites located at dimer interfaces. Streptococcus pyogenes Dps-like peroxide resistance protein (Dpr) has been previously found to protect the catalase-lacking S. pyogenes bacterium from oxidative stress. We have determined the crystal structure of S. pyogenes Dpr, the second Dpr structure from a streptococcal bacterium, in iron-free and iron-bound forms at 2.0- and 1.93-A resolution, respectively. The iron binds to well-conserved sites at dimer interfaces and is coordinated directly to Asp77 and Glu81 from one monomer, His50 from a twofold symmetry-related monomer, a glycerol molecule, and a water molecule. Upon iron binding, Asp77 and Glu81 change conformation. Site-directed mutagenesis of active-site residues His50, His62, Asp66, Asp77, and Glu81 to Ala revealed a dramatic decrease in iron incorporation. A short helix at the N-terminal was found in a different position compared with other Dps-like proteins. Two types of pores were identified in the dodecamer. Although the N-terminal pore was found to be similar to that of other Dps-like proteins, the C-terminal pore was found to be blocked by bulky Tyr residues instead of small residues present in other Dps-like proteins.

-	~~{{STRUCTURE_2wlu\| PDB=2wlu \| SCENE= }}~~	+	Crystal structures of Streptococcus pyogenes Dpr reveal a dodecameric iron-binding protein with a ferroxidase site.,Haikarainen T, Tsou CC, Wu JJ, Papageorgiou AC J Biol Inorg Chem. 2009 Sep 2. PMID:19727858<ref>PMID:19727858</ref>

-	~~===IRON-BOUND CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES DPR===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19727858}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wlu]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019727858<~~/~~ref~~><~~ref group="xtra">PMID:018541662</ref><references group="xtra"~~/>	+
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
	[[Category: Streptococcus pyogenes]]		[[Category: Streptococcus pyogenes]]

OCA at 13:05, 30 January 2013

OCA — Wed, 30 Jan 2013 13:05:33 GMT

←Older revision		Revision as of 13:05, 30 January 2013
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	[[Image:2wlu.png\|left\|200px]]		[[Image:2wlu.png\|left\|200px]]

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	{{STRUCTURE_2wlu\| PDB=2wlu \| SCENE= }}		{{STRUCTURE_2wlu\| PDB=2wlu \| SCENE= }}

	===IRON-BOUND CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES DPR===		===IRON-BOUND CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES DPR===

-
-	<!--
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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19727858~~</ref><ref group="xtra">PMID:~~18541662~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019727858</ref><ref group="xtra">PMID:018541662</ref><references group="xtra"/>
	[[Category: Ferroxidase]]		[[Category: Ferroxidase]]
	[[Category: Streptococcus pyogenes]]		[[Category: Streptococcus pyogenes]]

OCA: Protected "2wlu" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 18:03:50 GMT

Protected "2wlu" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:03, 14 March 2011

OCA at 18:03, 14 March 2011

OCA — Mon, 14 Mar 2011 18:03:48 GMT

←Older revision		Revision as of 18:03, 14 March 2011
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-	{{Seed}}
	[[Image:2wlu.png\|left\|200px]]		[[Image:2wlu.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2WLU~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA].	+	[[2wlu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WLU OCA].

	==Reference==		==Reference==
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	[[Category: Dna-binding]]		[[Category: Dna-binding]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 15:57:09 2010''