2wp7 - Revision history

OCA at 10:13, 20 December 2023

OCA — Wed, 20 Dec 2023 10:13:01 GMT

←Older revision		Revision as of 10:13, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='2wp7' size='340' side='right'caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wp7' size='340' side='right'caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [https://pdbe.org/2wp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [https://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [https://pdbe.org/2wp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [https://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DESI1_MOUSE DESI1_MOUSE]] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>	+	[https://www.uniprot.org/uniprot/DESI1_MOUSE DESI1_MOUSE] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Kim~~, J H~~]]	+	[[Category: Kim JH]]
-	[[Category: Oh~~, B H~~]]	+	[[Category: Oh BH]]
-	[[Category: Woo~~, J S]]~~	+	[[Category: Woo JS]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Ubiquitin-like protein~~]]	+

OCA at 11:12, 6 April 2022

OCA — Wed, 06 Apr 2022 11:12:52 GMT

←Older revision		Revision as of 11:12, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2wp7' size='340' side='right'caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wp7' size='340' side='right'caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [~~http~~://pdbe.org/2wp7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [https://pdbe.org/2wp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [https://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DESI1_MOUSE DESI1_MOUSE]] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>	+	[[https://www.uniprot.org/uniprot/DESI1_MOUSE DESI1_MOUSE]] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:01, 1 July 2020

OCA — Wed, 01 Jul 2020 09:01:06 GMT

←Older revision		Revision as of 09:01, 1 July 2020
Line 1:		Line 1:

	==Crystal structure of deSUMOylase(DUF862)==		==Crystal structure of deSUMOylase(DUF862)==
-	<StructureSection load='2wp7' size='340' side='right' caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2wp7' size='340' side='right'caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://pdbe.org/2wp7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://pdbe.org/2wp7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Kim, J H]]		[[Category: Kim, J H]]

OCA at 09:44, 26 September 2018

OCA — Wed, 26 Sep 2018 09:44:10 GMT

←Older revision		Revision as of 09:44, 26 September 2018
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wp7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wp7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:01, 4 August 2016

OCA — Thu, 04 Aug 2016 21:01:20 GMT

←Older revision		Revision as of 21:01, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of deSUMOylase(DUF862)==		==Crystal structure of deSUMOylase(DUF862)==
	<StructureSection load='2wp7' size='340' side='right' caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wp7' size='340' side='right' caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://pdbe.org/2wp7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wp7 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~PPDE2_MOUSE PPDE2_MOUSE~~]] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>	+	[[http://www.uniprot.org/uniprot/DESI1_MOUSE DESI1_MOUSE]] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wp7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wp7" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Kim, J H]]		[[Category: Kim, J H]]
	[[Category: Oh, B H]]		[[Category: Oh, B H]]

OCA at 19:37, 24 December 2014

OCA — Wed, 24 Dec 2014 19:37:10 GMT

←Older revision		Revision as of 19:37, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PPDE2_MOUSE PPDE2_MOUSE]] Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46.<ref>PMID:22370726</ref> <ref>PMID:22498933</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 23:
	Crystal structure of DeSI-1, a novel deSUMOylase belonging to a putative isopeptidase superfamily.,Suh HY, Kim JH, Woo JS, Ku B, Shin EJ, Yun Y, Oh BH Proteins. 2012 Apr 13. doi: 10.1002/prot.24093. PMID:22498933<ref>PMID:22498933</ref>		Crystal structure of DeSI-1, a novel deSUMOylase belonging to a putative isopeptidase superfamily.,Suh HY, Kim JH, Woo JS, Ku B, Shin EJ, Yun Y, Oh BH Proteins. 2012 Apr 13. doi: 10.1002/prot.24093. PMID:22498933<ref>PMID:22498933</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 28:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Kim, J H.]]	+	[[Category: Kim, J H]]
-	[[Category: Oh, B H.]]	+	[[Category: Oh, B H]]
-	[[Category: Woo, J S.]]	+	[[Category: Woo, J S]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Ubiquitin-like protein]]		[[Category: Ubiquitin-like protein]]

OCA at 09:50, 21 May 2014

OCA — Wed, 21 May 2014 09:50:47 GMT

←Older revision		Revision as of 09:50, 21 May 2014
Line 1:		Line 1:
-	[[~~Image~~:2wp7.~~png\|left~~\|200px]]	+	==Crystal structure of deSUMOylase(DUF862)==
		+	<StructureSection load='2wp7' size='340' side='right' caption='[[2wp7]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WP7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wp7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2wp7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wp7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Post-translational modification by SUMO can be reversed by SENPs, the first known class of deSUMOylase. Recently, we identified a new deSUMOylating enzyme DeSI-1, which is distinct from SENPs and belongs to the putative deubiquitinating isopeptidase PPPDE superfamily. Herein, we report the crystal structure of DeSI-1, revealing that this enzyme forms a homodimer and that the groove between the two subunits is the active site harboring two absolutely conserved cysteine and histidine residues which form a catalytic dyad. We also show that DeSI-1 exhibits an extremely low endopeptidase activity toward precursor forms of SUMO-1 and SUMO-2, unlike SENPs. Proteins 2012. (c) 2012 Wiley-Liss, Inc.

-	~~{{STRUCTURE_2wp7\| PDB=2wp7 \| SCENE= }}~~	+	Crystal structure of DeSI-1, a novel deSUMOylase belonging to a putative isopeptidase superfamily.,Suh HY, Kim JH, Woo JS, Ku B, Shin EJ, Yun Y, Oh BH Proteins. 2012 Apr 13. doi: 10.1002/prot.24093. PMID:22498933<ref>PMID:22498933</ref>

-	~~===Crystal structure~~ of ~~deSUMOylase(DUF862)===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22498933}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wp7]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022498933<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Kim, J H.]]		[[Category: Kim, J H.]]

OCA at 04:36, 18 July 2012

OCA — Wed, 18 Jul 2012 04:36:13 GMT

←Older revision		Revision as of 04:36, 18 July 2012
Line 1:		Line 1:
	[[Image:2wp7.png\|left\|200px]]		[[Image:2wp7.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2wp7\| PDB=2wp7 \| SCENE= }}		{{STRUCTURE_2wp7\| PDB=2wp7 \| SCENE= }}

	===Crystal structure of deSUMOylase(DUF862)===		===Crystal structure of deSUMOylase(DUF862)===

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OCA: Protected "2wp7" [edit=sysop:move=sysop]

OCA — Wed, 25 Apr 2012 08:18:07 GMT

Protected "2wp7" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:18, 25 April 2012

OCA at 08:18, 25 April 2012

OCA — Wed, 25 Apr 2012 08:18:05 GMT

←Older revision		Revision as of 08:18, 25 April 2012
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-	~~{{Seed}}~~	+	[[Image:2wp7.png\|left\|200px]]
-	[[Image:2wp7.~~jpg~~\|left\|200px]]	+

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	{{STRUCTURE_2wp7\| PDB=2wp7 \| SCENE= }}		{{STRUCTURE_2wp7\| PDB=2wp7 \| SCENE= }}

-	===~~CRYSTAL STRUCTURE OF DESUMOYLASE~~(DUF862)===	+	===Crystal structure of deSUMOylase(DUF862)===

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		+	The line below this paragraph, {{ABSTRACT_PUBMED_22498933}}, adds the Publication Abstract to the page
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		+	{{ABSTRACT_PUBMED_22498933}}

	==About this Structure==		==About this Structure==
-	~~2WP7~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA].	+	[[2wp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP7 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022498933</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Kim, J H.]]		[[Category: Kim, J H.]]
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	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Ubiquitin-like protein]]		[[Category: Ubiquitin-like protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:45:02 2010''