2wvg - Revision history

OCA at 10:17, 20 December 2023

OCA — Wed, 20 Dec 2023 10:17:37 GMT

←Older revision		Revision as of 10:17, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='2wvg' size='340' side='right'caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wvg' size='340' side='right'caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"achromobacter_anaerobium"_(sic)_shimwell_1937 "achromobacter anaerobium" (sic) shimwell 1937~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WVG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WVG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wvh\|2wvh]], [[1zpd\|1zpd]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [https://pdbe.org/2wvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [https://www.ebi.ac.uk/pdbsum/2wvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [https://pdbe.org/2wvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [https://www.ebi.ac.uk/pdbsum/2wvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PDC_ZYMMO PDC_ZYMMO]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pyruvate decarboxylase~~]]	+	[[Category: Zymomonas mobilis]]
-	[[Category: Erixon, K]]	+	[[Category: Erixon K]]
-	[[Category: Leeper~~, F J~~]]	+	[[Category: Leeper FJ]]
-	[[Category: Luisi~~, B F~~]]	+	[[Category: Luisi BF]]
-	[[Category: Pei~~, X Y]]~~	+	[[Category: Pei XY]]
-	~~[[Category: Alcohol fermentation]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Thiamine diphosphate~~]]	+

OCA at 10:58, 7 July 2021

OCA — Wed, 07 Jul 2021 10:58:41 GMT

←Older revision		Revision as of 10:58, 7 July 2021
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	==Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis==		==Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis==
-	<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>	+	<StructureSection load='2wvg' size='340' side='right'caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"achromobacter_anaerobium"_(sic)_shimwell_1937 "achromobacter anaerobium" (sic) shimwell 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WVG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"achromobacter_anaerobium"_(sic)_shimwell_1937 "achromobacter anaerobium" (sic) shimwell 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WVG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wvh\|2wvh]], [[1zpd\|1zpd]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [~~http~~://pdbe.org/2wvg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wvg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [https://pdbe.org/2wvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [https://www.ebi.ac.uk/pdbsum/2wvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pyruvate decarboxylase]]		[[Category: Pyruvate decarboxylase]]
	[[Category: Erixon, K]]		[[Category: Erixon, K]]

OCA at 07:56, 6 March 2019

OCA — Wed, 06 Mar 2019 07:56:17 GMT

←Older revision		Revision as of 07:56, 6 March 2019
Line 1:		Line 1:

	==Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis==		==Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis==
-	<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>	+	<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_anaerobium"_(sic)_shimwell_1937 "achromobacter anaerobium" (sic) shimwell 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_anaerobium"_(sic)_shimwell_1937 "achromobacter anaerobium" (sic) shimwell 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>

OCA at 09:21, 3 October 2018

OCA — Wed, 03 Oct 2018 09:21:38 GMT

←Older revision		Revision as of 09:21, 3 October 2018
Line 1:		Line 1:
-	==~~STRUCTURAL INSIGHTS INTO THE PRE~~-~~REACTION STATE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS~~==	+
		+	==Structural insights into the pre-reaction state of pyruvate decarboxylase from Zymomonas mobilis==
	<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://pdbe.org/2wvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://pdbe.org/2wvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 18:31, 7 February 2016

OCA — Sun, 07 Feb 2016 18:31:37 GMT

←Older revision		Revision as of 18:31, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Zymomonas_mobilis Zymomonas mobilis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"achromobacter_anaerobium"_(sic)_shimwell_1937 "achromobacter anaerobium" (sic) shimwell 1937]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://pdbe.org/2wvg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wvg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wvg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Pyruvate decarboxylase]]		[[Category: Pyruvate decarboxylase]]
-	[[Category: Zymomonas mobilis]]
	[[Category: Erixon, K]]		[[Category: Erixon, K]]
	[[Category: Leeper, F J]]		[[Category: Leeper, F J]]

OCA at 08:00, 20 January 2015

OCA — Tue, 20 Jan 2015 08:00:52 GMT

←Older revision		Revision as of 08:00, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Pyruvate decarboxylase]]		[[Category: Pyruvate decarboxylase]]
	[[Category: Zymomonas mobilis]]		[[Category: Zymomonas mobilis]]
-	[[Category: Erixon, K.]]	+	[[Category: Erixon, K]]
-	[[Category: Leeper, F J.]]	+	[[Category: Leeper, F J]]
-	[[Category: Luisi, B F.]]	+	[[Category: Luisi, B F]]
-	[[Category: Pei, X Y.]]	+	[[Category: Pei, X Y]]
	[[Category: Alcohol fermentation]]		[[Category: Alcohol fermentation]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]

OCA at 06:36, 29 September 2014

OCA — Mon, 29 Sep 2014 06:36:14 GMT

←Older revision		Revision as of 06:36, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2wvg.~~png~~\|~~left~~\|200px]]	+	==STRUCTURAL INSIGHTS INTO THE PRE-REACTION STATE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS==
		+	<StructureSection load='2wvg' size='340' side='right' caption='[[2wvg]], [[Resolution\|resolution]] 1.75Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPU:2-{1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-METHYL-1H-1,2,3-TRIAZOL-4-YL}ETHYL+TRIHYDROGEN+DIPHOSPHATE'>TPU</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvh\|2wvh]], [[1zpd\|1zpd]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_decarboxylase Pyruvate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.1 4.1.1.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvg RCSB], [http://www.ebi.ac.uk/pdbsum/2wvg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pyruvate decarboxylase (PDC) uses thiamine diphosphate as an essential cofactor to catalyze the formation of acetaldehyde on the pathway of ethanol synthesis. Here we report the crystallographic image of a prereaction intermediate of a bacterial pyruvate decarboxylase prepared by cocrystallizing the enzyme with pyruvate and a stable analogue of the cofactor's activated ylid form. A second crystal structure of PDC in complex with fluoride shows that the ion organizes a water molecule that occludes the pyruvate binding site, accounting for the inhibitory effect of the halide. Also reported is a structure of the cofactor-free apo form, which when compared to the structure of the holo form indicates how thiamine diphosphate organizes the active site pocket of pyruvate decarboxylase to support catalysis. Guided by the structural and enzymatic data, we propose roles for several key residues in the catalytic mechanism.

-	~~{{STRUCTURE_2wvg\| PDB=2wvg \| SCENE= }}~~	+	Structural Insights into the Prereaction State of Pyruvate Decarboxylase from Zymomonas mobilis .,Pei XY, Erixon KM, Luisi BF, Leeper FJ Biochemistry. 2010 Feb 5. PMID:20099870<ref>PMID:20099870</ref>

-	~~===STRUCTURAL INSIGHTS INTO THE PRE-REACTION STATE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20099870}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2wvg]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Zymomonas_mobilis Zymomonas mobilis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA].~~	+

	==See Also==		==See Also==
	*[[Pyruvate decarboxylase\|Pyruvate decarboxylase]]		*[[Pyruvate decarboxylase\|Pyruvate decarboxylase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020099870<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Pyruvate decarboxylase]]		[[Category: Pyruvate decarboxylase]]
	[[Category: Zymomonas mobilis]]		[[Category: Zymomonas mobilis]]

OCA at 07:31, 20 October 2012

OCA — Sat, 20 Oct 2012 07:31:40 GMT

←Older revision		Revision as of 07:31, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2wvg]] is a 4 chain structure ~~of [[Pyruvate decarboxylase]]~~ with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA].	+	[[2wvg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVG OCA].

	==See Also==		==See Also==

OCA at 16:36, 25 July 2012

OCA — Wed, 25 Jul 2012 16:36:24 GMT

←Older revision		Revision as of 16:36, 25 July 2012
Line 1:		Line 1:
	[[Image:2wvg.png\|left\|200px]]		[[Image:2wvg.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2wvg", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2wvg\| PDB=2wvg \| SCENE= }}		{{STRUCTURE_2wvg\| PDB=2wvg \| SCENE= }}

	===STRUCTURAL INSIGHTS INTO THE PRE-REACTION STATE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS===		===STRUCTURAL INSIGHTS INTO THE PRE-REACTION STATE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS MOBILIS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20099870}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20099870 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20099870}}		{{ABSTRACT_PUBMED_20099870}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Pyruvate decarboxylase]]	+	*[[Pyruvate decarboxylase\|Pyruvate decarboxylase]]

	==Reference==		==Reference==

OCA: Protected "2wvg" [edit=sysop:move=sysop]

OCA — Sun, 30 Oct 2011 08:05:11 GMT

Protected "2wvg" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:05, 30 October 2011