2wvx - Revision history

OCA at 10:41, 13 April 2022

OCA — Wed, 13 Apr 2022 10:41:05 GMT

←Older revision		Revision as of 10:41, 13 April 2022
Line 3:		Line 3:
	<StructureSection load='2wvx' size='340' side='right'caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wvx' size='340' side='right'caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WVX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [~~http~~://pdbe.org/2wvx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wvx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [https://pdbe.org/2wvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [https://www.ebi.ac.uk/pdbsum/2wvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvx ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 14:58, 8 July 2020

OCA — Wed, 08 Jul 2020 14:58:37 GMT

←Older revision		Revision as of 14:58, 8 July 2020
Line 1:		Line 1:

	==Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482==		==Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482==
-	<StructureSection load='2wvx' size='340' side='right' caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2wvx' size='340' side='right'caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WVX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://pdbe.org/2wvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://pdbe.org/2wvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvx ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bactn]]		[[Category: Bactn]]
		+	[[Category: Large Structures]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Gilbert, H J]]		[[Category: Gilbert, H J]]

OCA at 09:05, 3 October 2018

OCA — Wed, 03 Oct 2018 09:05:21 GMT

←Older revision		Revision as of 09:05, 3 October 2018
Line 1:		Line 1:

-	==~~STRUCTURE OF THE FAMILY~~ GH92 ~~INVERTING MANNOSIDASE~~ BT3990 ~~FROM BACTEROIDES THETAIOTAOMICRON~~ VPI-5482==	+	==Structure of the Family GH92 Inverting Mannosidase BT3990 from Bacteroides thetaiotaomicron VPI-5482==
	<StructureSection load='2wvx' size='340' side='right' caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wvx' size='340' side='right' caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvx_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvx_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:31, 11 August 2016

OCA — Thu, 11 Aug 2016 11:31:12 GMT

←Older revision		Revision as of 11:31, 11 August 2016
Line 1:		Line 1:
		+
	==STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482==		==STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482==
	<StructureSection load='2wvx' size='340' side='right' caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2wvx' size='340' side='right' caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://pdbe.org/2wvx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wvx ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wvx ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2wvx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacteroides thetaiotaomicron~~]]	+	[[Category: Bactn]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Gilbert, H J]]		[[Category: Gilbert, H J]]

OCA at 08:51, 20 January 2015

OCA — Tue, 20 Jan 2015 08:51:13 GMT

←Older revision		Revision as of 08:51, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVX FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
-	[[Category: Davies, G J.]]	+	[[Category: Davies, G J]]
-	[[Category: Gilbert, H J.]]	+	[[Category: Gilbert, H J]]
-	[[Category: Suits, M D.L.]]	+	[[Category: Suits, M D.L]]
-	[[Category: Thompson, A.]]	+	[[Category: Thompson, A]]
-	[[Category: Zhu, Y.]]	+	[[Category: Zhu, Y]]
	[[Category: Bt3990]]		[[Category: Bt3990]]
	[[Category: Gh92]]		[[Category: Gh92]]
	[[Category: Glycoside hydrolase family 92]]		[[Category: Glycoside hydrolase family 92]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 01:47, 1 October 2014

OCA — Wed, 01 Oct 2014 01:47:50 GMT

←Older revision		Revision as of 01:47, 1 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2wvx.~~png~~\|~~left~~\|200px]]	+	==STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482==
		+	<StructureSection load='2wvx' size='340' side='right' caption='[[2wvx]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WVX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wvy\|2wvy]], [[2ww3\|2ww3]], [[2ww2\|2ww2]], [[2wvz\|2wvz]], [[2ww1\|2ww1]], [[2ww0\|2ww0]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wvx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wvx RCSB], [http://www.ebi.ac.uk/pdbsum/2wvx PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wv/2wvx_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Colonic bacteria, exemplified by Bacteroides thetaiotaomicron, play a key role in maintaining human health by harnessing large families of glycoside hydrolases (GHs) to exploit dietary polysaccharides and host glycans as nutrients. Such GH family expansion is exemplified by the 23 family GH92 glycosidases encoded by the B. thetaiotaomicron genome. Here we show that these are alpha-mannosidases that act via a single displacement mechanism to utilize host N-glycans. The three-dimensional structure of two GH92 mannosidases defines a family of two-domain proteins in which the catalytic center is located at the domain interface, providing acid (glutamate) and base (aspartate) assistance to hydrolysis in a Ca(2+)-dependent manner. The three-dimensional structures of the GH92s in complex with inhibitors provide insight into the specificity, mechanism and conformational itinerary of catalysis. Ca(2+) plays a key catalytic role in helping distort the mannoside away from its ground-state (4)C(1) chair conformation toward the transition state.

-	~~{{STRUCTURE_2wvx\| PDB=2wvx \| SCENE= }}~~	+	Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont.,Zhu Y, Suits MD, Thompson AJ, Chavan S, Dinev Z, Dumon C, Smith N, Moremen KW, Xiang Y, Siriwardena A, Williams SJ, Gilbert HJ, Davies GJ Nat Chem Biol. 2010 Feb;6(2):125-32. Epub 2009 Dec 27. PMID:20081828<ref>PMID:20081828</ref>

-	~~===STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20081828}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2wvx]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020081828<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Davies, G J.]]		[[Category: Davies, G J.]]

OCA: Protected "2wvx" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:14:37 GMT

Protected "2wvx" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:14, 7 January 2013

OCA at 21:14, 7 January 2013

OCA — Mon, 07 Jan 2013 21:14:35 GMT

←Older revision		Revision as of 21:14, 7 January 2013
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-	{{Seed}}
	[[Image:2wvx.png\|left\|200px]]		[[Image:2wvx.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2wvx\| PDB=2wvx \| SCENE= }}		{{STRUCTURE_2wvx\| PDB=2wvx \| SCENE= }}

	===STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482===		===STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482===

-
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	{{ABSTRACT_PUBMED_20081828}}		{{ABSTRACT_PUBMED_20081828}}

	==About this Structure==		==About this Structure==
-	~~2WVX~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA].	+	[[2wvx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20081828~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020081828</ref><references group="xtra"/>
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Davies, G J.]]		[[Category: Davies, G J.]]
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	[[Category: Glycoside hydrolase family 92]]		[[Category: Glycoside hydrolase family 92]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
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OCA at 13:33, 27 January 2010

OCA — Wed, 27 Jan 2010 13:33:51 GMT

←Older revision		Revision as of 13:33, 27 January 2010
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	===STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482===		===STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482===

		+
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		+	The line below this paragraph, {{ABSTRACT_PUBMED_20081828}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20081828 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20081828}}

	==About this Structure==		==About this Structure==
-	2WVX is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA].	+	2WVX is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WVX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20081828</ref><references group="xtra"/>
	[[Category: Bacteroides thetaiotaomicron]]		[[Category: Bacteroides thetaiotaomicron]]
	[[Category: Davies, G J.]]		[[Category: Davies, G J.]]
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	[[Category: Hydrolase]]		[[Category: Hydrolase]]

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OCA at 12:53, 30 December 2009

OCA — Wed, 30 Dec 2009 12:53:44 GMT

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-	[[Image:2wvx.~~jpg~~\|left\|200px]]	+	[[Image:2wvx.png\|left\|200px]]

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