2x1b - Revision history

OCA at 10:19, 9 May 2024

OCA — Thu, 09 May 2024 10:19:39 GMT

←Older revision		Revision as of 10:19, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='2x1b' size='340' side='right'caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2x1b' size='340' side='right'caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X1B FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2x1f\|2x1f]], [[2x1a\|2x1a]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [https://pdbe.org/2x1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [https://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [https://pdbe.org/2x1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [https://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RNA15_YEAST RNA15_YEAST] RNA-binding component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Binds to A-rich RNA sequence elements.<ref>PMID:7992054</ref> <ref>PMID:11344258</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Goldstone, D C~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: ~~Pancevac, C~~]]	+	[[Category: Goldstone DC]]
-	[[Category: ~~Ramos, A~~]]	+	[[Category: Pancevac C]]
-	[[Category: ~~Taylor, I~~ A]]	+	[[Category: Ramos A]]
-	[[Category: ~~Mrna processing]]~~	+	[[Category: Taylor IA]]
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 10:44, 13 April 2022

OCA — Wed, 13 Apr 2022 10:44:23 GMT

←Older revision		Revision as of 10:44, 13 April 2022
Line 3:		Line 3:
	<StructureSection load='2x1b' size='340' side='right'caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2x1b' size='340' side='right'caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2X1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X1B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2x1f\|2x1f]], [[2x1a\|2x1a]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [~~http~~://pdbe.org/2x1b PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [https://pdbe.org/2x1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [https://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 15:02, 8 July 2020

OCA — Wed, 08 Jul 2020 15:02:57 GMT

←Older revision		Revision as of 15:02, 8 July 2020
Line 1:		Line 1:

	==Structure of RNA15 RRM==		==Structure of RNA15 RRM==
-	<StructureSection load='2x1b' size='340' side='right' caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='2x1b' size='340' side='right'caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2X1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X1B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://pdbe.org/2x1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://pdbe.org/2x1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Goldstone, D C]]		[[Category: Goldstone, D C]]
	[[Category: Pancevac, C]]		[[Category: Pancevac, C]]

OCA at 09:47, 3 October 2018

OCA — Wed, 03 Oct 2018 09:47:40 GMT

←Older revision		Revision as of 09:47, 3 October 2018
Line 1:		Line 1:
-	==~~STRUCTURE OF~~ RNA15 RRM==	+
		+	==Structure of RNA15 RRM==
	<StructureSection load='2x1b' size='340' side='right' caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2x1b' size='340' side='right' caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://pdbe.org/2x1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://pdbe.org/2x1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x1b ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x1/2x1b_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x1/2x1b_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:38, 7 February 2016

OCA — Sun, 07 Feb 2016 21:38:44 GMT

←Older revision		Revision as of 21:38, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2x1b' size='340' side='right' caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2x1b' size='340' side='right' caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X1B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X1B FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://pdbe.org/2x1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x1b ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2x1b" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Goldstone, D C]]		[[Category: Goldstone, D C]]
	[[Category: Pancevac, C]]		[[Category: Pancevac, C]]

OCA at 09:46, 20 January 2015

OCA — Tue, 20 Jan 2015 09:46:33 GMT

←Older revision		Revision as of 09:46, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X1B FirstGlance]. <br>		<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X1B FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Goldstone, D C.]]	+	[[Category: Goldstone, D C]]
-	[[Category: Pancevac, C.]]	+	[[Category: Pancevac, C]]
-	[[Category: Ramos, A.]]	+	[[Category: Ramos, A]]
-	[[Category: Taylor, I A.]]	+	[[Category: Taylor, I A]]
	[[Category: Mrna processing]]		[[Category: Mrna processing]]
	[[Category: Nucleus]]		[[Category: Nucleus]]
	[[Category: Rna-binding]]		[[Category: Rna-binding]]
	[[Category: Transcription]]		[[Category: Transcription]]

OCA at 02:17, 1 October 2014

OCA — Wed, 01 Oct 2014 02:17:52 GMT

←Older revision		Revision as of 02:17, 1 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2x1b.~~png~~\|~~left~~\|200px]]	+	==STRUCTURE OF RNA15 RRM==
		+	<StructureSection load='2x1b' size='340' side='right' caption='[[2x1b]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X1B FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2x1f\|2x1f]], [[2x1a\|2x1a]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x1b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x1b RCSB], [http://www.ebi.ac.uk/pdbsum/2x1b PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x1/2x1b_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rna15 is a core subunit of cleavage factor IA (CFIA), an essential transcriptional 3'-end processing factor from Saccharomyces cerevisiae. CFIA is required for polyA site selection/cleavage targeting RNA sequences that surround polyadenylation sites in the 3'-UTR of RNA polymerase-II transcripts. RNA recognition by CFIA is mediated by an RNA recognition motif (RRM) contained in the Rna15 subunit of the complex. We show here that Rna15 has a strong and unexpected preference for GU containing RNAs and reveal the molecular basis for a base selectivity mechanism that accommodates G or U but discriminates against C and A bases. This mode of base selectivity is rather different to that observed in other RRM-RNA structures and is structurally conserved in CstF64, the mammalian counterpart of Rna15. Our observations provide evidence for a highly conserved mechanism of base recognition amongst the 3'-end processing complexes that interact with the U-rich or U/G-rich elements at 3'-end cleavage/polyadenylation sites.

-	~~{{STRUCTURE_2x1b\| PDB=2x1b \| SCENE= }}~~	+	Structure of the Rna15 RRM-RNA complex reveals the molecular basis of GU specificity in transcriptional 3'-end processing factors.,Pancevac C, Goldstone DC, Ramos A, Taylor IA Nucleic Acids Res. 2010 May;38(9):3119-32. Epub 2010 Jan 21. PMID:20097654<ref>PMID:20097654</ref>

-	~~===STRUCTURE OF RNA15 RRM===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20097654}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2x1b]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:020097654<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Goldstone, D C.]]		[[Category: Goldstone, D C.]]

OCA: Protected "2x1b" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 19:03:09 GMT

Protected "2x1b" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:03, 7 January 2013

OCA at 19:03, 7 January 2013

OCA — Mon, 07 Jan 2013 19:03:03 GMT

←Older revision		Revision as of 19:03, 7 January 2013
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-	{{Seed}}
	[[Image:2x1b.png\|left\|200px]]		[[Image:2x1b.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2x1b\| PDB=2x1b \| SCENE= }}		{{STRUCTURE_2x1b\| PDB=2x1b \| SCENE= }}

	===STRUCTURE OF RNA15 RRM===		===STRUCTURE OF RNA15 RRM===

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-	<!--
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	{{ABSTRACT_PUBMED_20097654}}		{{ABSTRACT_PUBMED_20097654}}

	==About this Structure==		==About this Structure==
-	~~2X1B~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA].	+	[[2x1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X1B OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20097654~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020097654</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Goldstone, D C.]]		[[Category: Goldstone, D C.]]
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	[[Category: Rna-binding]]		[[Category: Rna-binding]]
	[[Category: Transcription]]		[[Category: Transcription]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:37:40 2010''

OCA at 04:33, 26 May 2010

OCA — Wed, 26 May 2010 04:33:30 GMT

←Older revision		Revision as of 04:33, 26 May 2010
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	{{Seed}}		{{Seed}}
-	[[Image:2x1b.~~jpg~~\|left\|200px]]	+	[[Image:2x1b.png\|left\|200px]]

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-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 3 09~~:38:32 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:37:40 2010''