2x6c - Revision history

OCA at 10:24, 20 December 2023

OCA — Wed, 20 Dec 2023 10:24:42 GMT

←Older revision		Revision as of 10:24, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='2x6c' size='340' side='right'caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2x6c' size='340' side='right'caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_31632 Atcc 31632~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [https://pdbe.org/2x6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [https://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [https://pdbe.org/2x6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [https://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/IRK10_MAGMG IRK10_MAGMG] Inward rectifier potassium channel that mediates potassium uptake into the cell. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification may be achieved by the blockage of outward current by cytoplasmic divalent metal ions and polyamines. Complements an E.coli mutant that is defective in K(+) uptake.<ref>PMID:20876570</ref> <ref>PMID:20564790</ref> <ref>PMID:22231399</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 31632]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Caputo, A T~~]]	+	[[Category: Magnetospirillum magnetotacticum]]
-	[[Category: ~~Clarke, O B~~]]	+	[[Category: Caputo AT]]
-	[[Category: ~~Gulbis, J M~~]]	+	[[Category: Clarke OB]]
-	[[Category: ~~Hill, A P~~]]	+	[[Category: Gulbis JM]]
-	[[Category: ~~Smith, B J~~]]	+	[[Category: Hill AP]]
-	[[Category: ~~Vandenberg, J I~~]]	+	[[Category: Smith BJ]]
-	[[Category: ~~Integral membrane protein]]~~	+	[[Category: Vandenberg JI]]
-	~~[[Category: Ion channel]]~~	+
-	~~[[Category: Metal transport~~]]	+

OCA at 10:46, 13 April 2022

OCA — Wed, 13 Apr 2022 10:46:16 GMT

←Older revision		Revision as of 10:46, 13 April 2022
Line 3:		Line 3:
	<StructureSection load='2x6c' size='340' side='right'caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2x6c' size='340' side='right'caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2X6C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [~~http~~://pdbe.org/2x6c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [https://pdbe.org/2x6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [https://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 15:05, 8 July 2020

OCA — Wed, 08 Jul 2020 15:05:48 GMT

←Older revision		Revision as of 15:05, 8 July 2020
Line 1:		Line 1:

	==Potassium Channel from Magnetospirillum Magnetotacticum==		==Potassium Channel from Magnetospirillum Magnetotacticum==
-	<StructureSection load='2x6c' size='340' side='right' caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='2x6c' size='340' side='right'caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2X6C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X6C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://pdbe.org/2x6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://pdbe.org/2x6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Potassium ~~Channel~~\|Potassium ~~Channel~~]]	+	*[[Potassium channel 3D structures\|Potassium channel 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 31632]]		[[Category: Atcc 31632]]
		+	[[Category: Large Structures]]
	[[Category: Caputo, A T]]		[[Category: Caputo, A T]]
	[[Category: Clarke, O B]]		[[Category: Clarke, O B]]

OCA at 09:49, 3 October 2018

OCA — Wed, 03 Oct 2018 09:49:26 GMT

←Older revision		Revision as of 09:49, 3 October 2018
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/2x6c_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/2x6c_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:08, 11 August 2016

OCA — Thu, 11 Aug 2016 13:08:55 GMT

←Older revision		Revision as of 13:08, 11 August 2016
Line 1:		Line 1:
		+
	==Potassium Channel from Magnetospirillum Magnetotacticum==		==Potassium Channel from Magnetospirillum Magnetotacticum==
	<StructureSection load='2x6c' size='340' side='right' caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2x6c' size='340' side='right' caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X6C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_31632 Atcc 31632]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X6C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://pdbe.org/2x6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6c ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2x6c ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2x6c" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Magnetospirillum magnetotacticum~~]]	+	[[Category: Atcc 31632]]
	[[Category: Caputo, A T]]		[[Category: Caputo, A T]]
	[[Category: Clarke, O B]]		[[Category: Clarke, O B]]

OCA at 10:52, 20 January 2015

OCA — Tue, 20 Jan 2015 10:52:33 GMT

←Older revision		Revision as of 10:52, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X6C FirstGlance]. <br>		<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X6C FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Magnetospirillum magnetotacticum]]		[[Category: Magnetospirillum magnetotacticum]]
-	[[Category: Caputo, A T.]]	+	[[Category: Caputo, A T]]
-	[[Category: Clarke, O B.]]	+	[[Category: Clarke, O B]]
-	[[Category: Gulbis, J M.]]	+	[[Category: Gulbis, J M]]
-	[[Category: Hill, A P.]]	+	[[Category: Hill, A P]]
-	[[Category: Smith, B J.]]	+	[[Category: Smith, B J]]
-	[[Category: Vandenberg, J I.]]	+	[[Category: Vandenberg, J I]]
	[[Category: Integral membrane protein]]		[[Category: Integral membrane protein]]
	[[Category: Ion channel]]		[[Category: Ion channel]]
	[[Category: Metal transport]]		[[Category: Metal transport]]

OCA at 01:03, 2 October 2014

OCA — Thu, 02 Oct 2014 01:03:09 GMT

←Older revision		Revision as of 01:03, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2x6c.~~png~~\|~~left~~\|200px]]	+	==Potassium Channel from Magnetospirillum Magnetotacticum==
		+	<StructureSection load='2x6c' size='340' side='right' caption='[[2x6c]], [[Resolution\|resolution]] 2.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X6C FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene>, <scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xl4\|1xl4]], [[1xl6\|1xl6]], [[2x6a\|2x6a]], [[2x6b\|2x6b]], [[2wln\|2wln]], [[2wlo\|2wlo]], [[2wlj\|2wlj]], [[2wll\|2wll]], [[2wli\|2wli]], [[2wlm\|2wlm]], [[2wlk\|2wlk]], [[2wlh\|2wlh]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2x6c RCSB], [http://www.ebi.ac.uk/pdbsum/2x6c PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x6/2x6c_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Potassium channels embedded in cell membranes employ gates to regulate K+ current. While a specific constriction in the permeation pathway has historically been implicated in gating, recent reports suggest that the signature ion selectivity filter located in the outer membrane leaflet may be equally important. Inwardly rectifying K+ channels also control the directionality of flow, using intracellular polyamines to stem ion efflux by a valve-like action. This study presents crystallographic evidence of interdependent gates in the conduction pathway and reveals the mechanism of polyamine block. Reorientation of the intracellular domains, concomitant with activation, instigates polyamine release from intracellular binding sites to block the permeation pathway. Conformational adjustments of the slide helices, achieved by rotation of the cytoplasmic assembly relative to the pore, are directly correlated to the ion configuration in the selectivity filter. Ion redistribution occurs irrespective of the constriction, suggesting a more expansive role of the selectivity filter in gating than previously appreciated.

-	~~{{STRUCTURE_2x6c\| PDB=2x6c \| SCENE= }}~~	+	Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels.,Clarke OB, Caputo AT, Hill AP, Vandenberg JI, Smith BJ, Gulbis JM Cell. 2010 Jun 11;141(6):1018-29. PMID:20564790<ref>PMID:20564790</ref>

-	~~===Potassium Channel from Magnetospirillum Magnetotacticum===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20564790}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2x6c]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA].~~	+

	==See Also==		==See Also==
	*[[Potassium Channel\|Potassium Channel]]		*[[Potassium Channel\|Potassium Channel]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020564790<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Magnetospirillum magnetotacticum]]		[[Category: Magnetospirillum magnetotacticum]]
	[[Category: Caputo, A T.]]		[[Category: Caputo, A T.]]

OCA at 07:07, 20 October 2012

OCA — Sat, 20 Oct 2012 07:07:14 GMT

←Older revision		Revision as of 07:07, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2x6c]] is a 1 chain structure ~~of [[Potassium Channel]]~~ with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA].	+	[[2x6c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA].

	==See Also==		==See Also==

OCA: Protected "2x6c" [edit=sysop:move=sysop]

OCA — Wed, 27 Jun 2012 04:46:04 GMT

Protected "2x6c" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:46, 27 June 2012

OCA at 04:46, 27 June 2012

OCA — Wed, 27 Jun 2012 04:46:03 GMT

←Older revision		Revision as of 04:46, 27 June 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:2x6c.png\|left\|200px]]
-	[[Image:2x6c.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2x6c", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2x6c\| PDB=2x6c \| SCENE= }}		{{STRUCTURE_2x6c\| PDB=2x6c \| SCENE= }}

-	===~~POTASSIUM CHANNEL FROM MAGNETOSPIRILLUM MAGNETOTACTICUM~~===	+	===Potassium Channel from Magnetospirillum Magnetotacticum===

		+	{{ABSTRACT_PUBMED_20564790}}

	==About this Structure==		==About this Structure==
-	~~2X6C~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA].	+	[[2x6c]] is a 1 chain structure of [[Potassium Channel]] with sequence from [http://en.wikipedia.org/wiki/Magnetospirillum_magnetotacticum Magnetospirillum magnetotacticum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6C OCA].
		+
		+	==See Also==
		+	*[[Potassium Channel\|Potassium Channel]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:020564790</ref><references group="xtra"/>
	[[Category: Magnetospirillum magnetotacticum]]		[[Category: Magnetospirillum magnetotacticum]]
	[[Category: Caputo, A T.]]		[[Category: Caputo, A T.]]
Line 25:		Line 25:
	[[Category: Ion channel]]		[[Category: Ion channel]]
	[[Category: Metal transport]]		[[Category: Metal transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:47:10 2010''