2xep - Revision history

OCA at 10:38, 16 August 2023

OCA — Wed, 16 Aug 2023 10:38:15 GMT

←Older revision		Revision as of 10:38, 16 August 2023
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	<StructureSection load='2xep' size='340' side='right'caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2xep' size='340' side='right'caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~As_4.1611 As 4.1611~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEP FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2xf3\|2xf3]]~~, ~~[[2xfs\|2xfs]], [[2xft\|2xft]], [[2xgn\|2xgn]], [[2xh9\|2xh9]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [https://pdbe.org/2xep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [https://www.ebi.ac.uk/pdbsum/2xep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xep ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [https://pdbe.org/2xep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [https://www.ebi.ac.uk/pdbsum/2xep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xep ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8KRB7_STRCL Q8KRB7_STRCL]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: As 4 1611]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Andersson, I]]	+	[[Category: Streptomyces clavuligerus]]
-	[[Category: Dubus, A]]	+	[[Category: Andersson I]]
-	[[Category: Genereux, C]]	+	[[Category: Dubus A]]
-	[[Category: Iqbal, A]]	+	[[Category: Genereux C]]
-	[[Category: Ivison, D]]	+	[[Category: Iqbal A]]
-	[[Category: Kershaw~~, N J~~]]	+	[[Category: Ivison D]]
-	[[Category: Schofield~~, C J~~]]	+	[[Category: Kershaw NJ]]
-	[[Category: Valegard, K]]	+	[[Category: Schofield CJ]]
-	~~[[Category: Hydrolase~~]]	+	[[Category: Valegard K]]

OCA at 08:39, 10 November 2021

OCA — Wed, 10 Nov 2021 08:39:07 GMT

←Older revision		Revision as of 08:39, 10 November 2021
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	<StructureSection load='2xep' size='340' side='right'caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2xep' size='340' side='right'caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2XEP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEP FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xf3\|2xf3]], [[2xfs\|2xfs]], [[2xft\|2xft]], [[2xgn\|2xgn]], [[2xh9\|2xh9]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2xf3\|2xf3]], [[2xfs\|2xfs]], [[2xft\|2xft]], [[2xgn\|2xgn]], [[2xh9\|2xh9]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [~~http~~://pdbe.org/2xep PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2xep PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2xep ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [https://pdbe.org/2xep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [https://www.ebi.ac.uk/pdbsum/2xep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xep ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:19, 25 December 2019

OCA — Wed, 25 Dec 2019 14:19:05 GMT

←Older revision		Revision as of 14:19, 25 December 2019
Line 1:		Line 1:

	==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==		==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==
-	<StructureSection load='2xep' size='340' side='right' caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='2xep' size='340' side='right'caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEP FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: As 4 1611]]		[[Category: As 4 1611]]
		+	[[Category: Large Structures]]
	[[Category: Andersson, I]]		[[Category: Andersson, I]]
	[[Category: Dubus, A]]		[[Category: Dubus, A]]

OCA at 02:31, 5 August 2016

OCA — Fri, 05 Aug 2016 02:31:55 GMT

←Older revision		Revision as of 02:31, 5 August 2016
Line 1:		Line 1:
		+
	==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==		==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==
	<StructureSection load='2xep' size='340' side='right' caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='2xep' size='340' side='right' caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_clavuligerus Streptomyces clavuligerus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xf3\|2xf3]], [[2xfs\|2xfs]], [[2xft\|2xft]], [[2xgn\|2xgn]], [[2xh9\|2xh9]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xf3\|2xf3]], [[2xfs\|2xfs]], [[2xft\|2xft]], [[2xgn\|2xgn]], [[2xh9\|2xh9]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [http://www.ebi.ac.uk/pdbsum/2xep PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [http://pdbe.org/2xep PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [http://www.ebi.ac.uk/pdbsum/2xep PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xep ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2xep" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces clavuligerus~~]]	+	[[Category: As 4 1611]]
	[[Category: Andersson, I]]		[[Category: Andersson, I]]
	[[Category: Dubus, A]]		[[Category: Dubus, A]]

OCA at 13:00, 18 December 2014

OCA — Thu, 18 Dec 2014 13:00:24 GMT

←Older revision		Revision as of 13:00, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}~~	+	==Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway==
-	===Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway===	+	<StructureSection load='2xep' size='340' side='right' caption='[[2xep]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23897479}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2xf3\|2xf3]], [[2xfs\|2xfs]], [[2xft\|2xft]], [[2xgn\|2xgn]], [[2xh9\|2xh9]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xep OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xep RCSB], [http://www.ebi.ac.uk/pdbsum/2xep PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Structural and biochemical studies of the orf12 gene product (ORF12) from the clavulanic acid (CA) biosynthesis gene cluster are described. Sequence and crystallographic analyses reveal two domains: a C-terminal penicillin-binding protein (PBP)/beta-lactamase-type fold with highest structural similarity to the class A beta-lactamases fused to an N-terminal domain with a fold similar to steroid isomerases and polyketide cyclases. The C-terminal domain of ORF12 did not show beta-lactamase or PBP activity for the substrates tested, but did show low-level esterase activity towards 3'-O-acetyl cephalosporins and a thioester substrate. Mutagenesis studies imply that Ser173, which is present in a conserved SXXK motif, acts as a nucleophile in catalysis, consistent with studies of related esterases, beta-lactamases and D-Ala carboxypeptidases. Structures of wild-type ORF12 and of catalytic residue variants were obtained in complex with and in the absence of clavulanic acid. The role of ORF12 in clavulanic acid biosynthesis is unknown, but it may be involved in the epimerization of (3S,5S)-clavaminic acid to (3R,5R)-clavulanic acid.

-	~~==About this Structure==~~	+	Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.,Valegard K, Iqbal A, Kershaw NJ, Ivison D, Genereux C, Dubus A, Blikstad C, Demetriades M, Hopkinson RJ, Lloyd AJ, Roper DI, Schofield CJ, Andersson I, McDonough MA Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1567-79. doi:, 10.1107/S0907444913011013. Epub 2013 Jul 20. PMID:23897479<ref>PMID:23897479</ref>
-	~~[[2xep]] is a 2 chain structure with sequence~~ from ~~[http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2XEP OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023897479</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Streptomyces clavuligerus]]		[[Category: Streptomyces clavuligerus]]
-	[[Category: Andersson, I.]]	+	[[Category: Andersson, I]]
-	[[Category: Dubus, A.]]	+	[[Category: Dubus, A]]
-	[[Category: Genereux, C.]]	+	[[Category: Genereux, C]]
-	[[Category: Iqbal, A.]]	+	[[Category: Iqbal, A]]
-	[[Category: Ivison, D.]]	+	[[Category: Ivison, D]]
-	[[Category: Kershaw, N J.]]	+	[[Category: Kershaw, N J]]
-	[[Category: Schofield, C J.]]	+	[[Category: Schofield, C J]]
-	[[Category: Valegard, K.]]	+	[[Category: Valegard, K]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 19:31, 7 August 2013

OCA — Wed, 07 Aug 2013 19:31:32 GMT

←Older revision		Revision as of 19:31, 7 August 2013
Line 1:		Line 1:
	{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}		{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}
	===Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway===		===Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway===
		+	{{ABSTRACT_PUBMED_23897479}}

	==About this Structure==		==About this Structure==
	[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA].		[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023897479</ref><references group="xtra"/><references/>
	[[Category: Streptomyces clavuligerus]]		[[Category: Streptomyces clavuligerus]]
	[[Category: Andersson, I.]]		[[Category: Andersson, I.]]

OCA at 03:49, 1 August 2013

OCA — Thu, 01 Aug 2013 03:49:38 GMT

←Older revision		Revision as of 03:49, 1 August 2013
Line 1:		Line 1:
	{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}		{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}
-	===~~STRUCTURAL AND MECHANISTIC STUDIES ON A CEPHALOSPORIN ESTERASE FROM THE CLAVULANIC ACID BIOSYNTHESIS PATHWAY~~===	+	===Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway===

	==About this Structure==		==About this Structure==

OCA at 08:39, 2 May 2013

OCA — Thu, 02 May 2013 08:39:23 GMT

←Older revision		Revision as of 08:39, 2 May 2013
Line 1:		Line 1:
-	[[Image:2xep.jpg\|left\|200px]]
-
-	<!--
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-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}		{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}
-
	===STRUCTURAL AND MECHANISTIC STUDIES ON A CEPHALOSPORIN ESTERASE FROM THE CLAVULANIC ACID BIOSYNTHESIS PATHWAY===		===STRUCTURAL AND MECHANISTIC STUDIES ON A CEPHALOSPORIN ESTERASE FROM THE CLAVULANIC ACID BIOSYNTHESIS PATHWAY===
-

	==About this Structure==		==About this Structure==

OCA: Protected "2xep" [edit=sysop:move=sysop]

OCA — Wed, 29 Jun 2011 06:12:43 GMT

Protected "2xep" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:12, 29 June 2011

OCA at 06:12, 29 June 2011

OCA — Wed, 29 Jun 2011 06:12:37 GMT

←Older revision		Revision as of 06:12, 29 June 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2xep.jpg\|left\|200px]]

-	The ~~entry 2xep~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2xep", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2xep\| PDB=2xep \| SCENE= }}

-	~~Authors: Iqbal,~~ A~~., Valegard, K., Kershaw, N.J., Ivison, D., Genereux, C., Dubus, A., Andersson, I., Schofield, C.J.~~	+	===STRUCTURAL AND MECHANISTIC STUDIES ON A CEPHALOSPORIN ESTERASE FROM THE CLAVULANIC ACID BIOSYNTHESIS PATHWAY===

-	Description: Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed May 26 08~~:13:~~22 2010''~~	+	==About this Structure==
		+	[[2xep]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEP OCA].
		+	[[Category: Streptomyces clavuligerus]]
		+	[[Category: Andersson, I.]]
		+	[[Category: Dubus, A.]]
		+	[[Category: Genereux, C.]]
		+	[[Category: Iqbal, A.]]
		+	[[Category: Ivison, D.]]
		+	[[Category: Kershaw, N J.]]
		+	[[Category: Schofield, C J.]]
		+	[[Category: Valegard, K.]]
		+	[[Category: Hydrolase]]