2xig - Revision history

OCA at 07:11, 1 May 2024

OCA — Wed, 01 May 2024 07:11:05 GMT

←Older revision		Revision as of 07:11, 1 May 2024
Line 10:		Line 10:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.		[https://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Fur, the ferric uptake regulator, is a transcription factor that controls iron metabolism in bacteria. Binding of ferrous iron to Fur triggers a conformational change that activates the protein for binding to specific DNA sequences named Fur boxes. In Helicobacter pylori, HpFur is involved in acid response and is important for gastric colonization in model animals. Here we present the crystal structure of a functionally active HpFur mutant (HpFur2M; C78S-C150S) bound to zinc. Although its fold is similar to that of other Fur and Fur-like proteins, the crystal structure of HpFur reveals a unique structured N-terminal extension and an unusual C-terminal helix. The structure also shows three metal binding sites: S1 the structural ZnS(4) site previously characterized biochemically in HpFur and the two zinc sites identified in other Fur proteins. Site-directed mutagenesis and spectroscopy analyses of purified wild-type HpFur and various mutants show that the two metal binding sites common to other Fur proteins can be also metallated by cobalt. DNA protection and circular dichroism experiments demonstrate that, while these two sites influence the affinity of HpFur for DNA, only one is absolutely required for DNA binding and could be responsible for the conformational changes of Fur upon metal binding while the other is a secondary site.
-
-	The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites.,Dian C, Vitale S, Leonard GA, Bahlawane C, Fauquant C, Leduc D, Muller C, de Reuse H, Michaud-Soret I, Terradot L Mol Microbiol. 2011 Jan 5. doi: 10.1111/j.1365-2958.2010.07517.x. PMID:21208302<ref>PMID:21208302</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2xig" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:45, 17 January 2024

OCA — Wed, 17 Jan 2024 12:45:35 GMT

←Older revision		Revision as of 12:45, 17 January 2024
Line 3:		Line 3:
	<StructureSection load='2xig' size='340' side='right'caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2xig' size='340' side='right'caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Campylobacter_pylori Campylobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XIG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XIG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [https://pdbe.org/2xig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [https://www.ebi.ac.uk/pdbsum/2xig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [https://pdbe.org/2xig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [https://www.ebi.ac.uk/pdbsum/2xig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY]] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.	+	[https://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Campylobacter~~ pylori]]	+	[[Category: Helicobacter pylori 26695]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bahlawane, C]]	+	[[Category: Bahlawane C]]
-	[[Category: Dian, C]]	+	[[Category: Dian C]]
-	[[Category: Fauquant, F]]	+	[[Category: Fauquant F]]
-	[[Category: Leonard~~, G A~~]]	+	[[Category: Leonard GA]]
-	[[Category: Michaud-Soret, I]]	+	[[Category: Michaud-Soret I]]
-	[[Category: Muller, C]]	+	[[Category: Muller C]]
-	~~[[Category: Reuse, H de~~]]	+	[[Category: Terradot L]]
-	[[Category: Terradot, L]]	+	[[Category: Vitale S]]
-	[[Category: Vitale, S]]	+	[[Category: De Reuse H]]
-	[[Category: ~~Homeostasis]]~~	+
-	~~[[Category: Hpfur]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 10:53, 13 April 2022

OCA — Wed, 13 Apr 2022 10:53:32 GMT

←Older revision		Revision as of 10:53, 13 April 2022
Line 3:		Line 3:
	<StructureSection load='2xig' size='340' side='right'caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2xig' size='340' side='right'caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2XIG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XIG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [~~http~~://pdbe.org/2xig PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2xig PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [https://pdbe.org/2xig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [https://www.ebi.ac.uk/pdbsum/2xig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY]] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.	+	[[https://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY]] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:15, 8 July 2020

OCA — Wed, 08 Jul 2020 15:15:23 GMT

←Older revision		Revision as of 15:15, 8 July 2020
Line 1:		Line 1:

	==The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites==		==The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites==
-	<StructureSection load='2xig' size='340' side='right' caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='2xig' size='340' side='right'caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2XIG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XIG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [http://pdbe.org/2xig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [http://www.ebi.ac.uk/pdbsum/2xig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [http://pdbe.org/2xig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [http://www.ebi.ac.uk/pdbsum/2xig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Campylobacter pylori]]		[[Category: Campylobacter pylori]]
		+	[[Category: Large Structures]]
	[[Category: Bahlawane, C]]		[[Category: Bahlawane, C]]
	[[Category: Dian, C]]		[[Category: Dian, C]]

OCA at 09:17, 3 October 2018

OCA — Wed, 03 Oct 2018 09:17:59 GMT

←Older revision		Revision as of 09:17, 3 October 2018
Line 1:		Line 1:

-	==~~THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES~~==	+	==The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites==
	<StructureSection load='2xig' size='340' side='right' caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2xig' size='340' side='right' caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 29:		Line 29:
	[[Category: Michaud-Soret, I]]		[[Category: Michaud-Soret, I]]
	[[Category: Muller, C]]		[[Category: Muller, C]]
-	[[Category: Reuse, H De]]	+	[[Category: Reuse, H de]]
	[[Category: Terradot, L]]		[[Category: Terradot, L]]
	[[Category: Vitale, S]]		[[Category: Vitale, S]]

OCA at 08:18, 5 August 2016

OCA — Fri, 05 Aug 2016 08:18:12 GMT

←Older revision		Revision as of 08:18, 5 August 2016
Line 1:		Line 1:
		+
	==THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES==		==THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES==
	<StructureSection load='2xig' size='340' side='right' caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2xig' size='340' side='right' caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori Helicobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XIG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XIG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [http://www.ebi.ac.uk/pdbsum/2xig PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [http://pdbe.org/2xig PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [http://www.ebi.ac.uk/pdbsum/2xig PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2xig" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Helicobacter~~ pylori]]	+	[[Category: Campylobacter pylori]]
	[[Category: Bahlawane, C]]		[[Category: Bahlawane, C]]
	[[Category: Dian, C]]		[[Category: Dian, C]]

OCA at 00:38, 25 December 2014

OCA — Thu, 25 Dec 2014 00:38:26 GMT

←Older revision		Revision as of 00:38, 25 December 2014
Line 1:		Line 1:
-	[[~~Image:~~2xig.~~png~~\|~~left\|200px~~]]	+	==THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES==
		+	<StructureSection load='2xig' size='340' side='right' caption='[[2xig]], [[Resolution\|resolution]] 1.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XIG FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [http://www.ebi.ac.uk/pdbsum/2xig PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY]] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fur, the ferric uptake regulator, is a transcription factor that controls iron metabolism in bacteria. Binding of ferrous iron to Fur triggers a conformational change that activates the protein for binding to specific DNA sequences named Fur boxes. In Helicobacter pylori, HpFur is involved in acid response and is important for gastric colonization in model animals. Here we present the crystal structure of a functionally active HpFur mutant (HpFur2M; C78S-C150S) bound to zinc. Although its fold is similar to that of other Fur and Fur-like proteins, the crystal structure of HpFur reveals a unique structured N-terminal extension and an unusual C-terminal helix. The structure also shows three metal binding sites: S1 the structural ZnS(4) site previously characterized biochemically in HpFur and the two zinc sites identified in other Fur proteins. Site-directed mutagenesis and spectroscopy analyses of purified wild-type HpFur and various mutants show that the two metal binding sites common to other Fur proteins can be also metallated by cobalt. DNA protection and circular dichroism experiments demonstrate that, while these two sites influence the affinity of HpFur for DNA, only one is absolutely required for DNA binding and could be responsible for the conformational changes of Fur upon metal binding while the other is a secondary site.

-	~~{{STRUCTURE_2xig\| PDB=2xig \| SCENE= }}~~	+	The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites.,Dian C, Vitale S, Leonard GA, Bahlawane C, Fauquant C, Leduc D, Muller C, de Reuse H, Michaud-Soret I, Terradot L Mol Microbiol. 2011 Jan 5. doi: 10.1111/j.1365-2958.2010.07517.x. PMID:21208302<ref>PMID:21208302</ref>

-	~~===THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21208302}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2xig]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Helicobacter_pylori Helicobacter pylori]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021208302<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
-	[[Category: Bahlawane, C.]]	+	[[Category: Bahlawane, C]]
-	[[Category: Dian, C.]]	+	[[Category: Dian, C]]
-	[[Category: Fauquant, F.]]	+	[[Category: Fauquant, F]]
-	[[Category: Leonard, G A.]]	+	[[Category: Leonard, G A]]
-	[[Category: Michaud-Soret, I.]]	+	[[Category: Michaud-Soret, I]]
-	[[Category: Muller, C.]]	+	[[Category: Muller, C]]
-	[[Category: Reuse, H De.]]	+	[[Category: Reuse, H De]]
-	[[Category: Terradot, L.]]	+	[[Category: Terradot, L]]
-	[[Category: Vitale, S.]]	+	[[Category: Vitale, S]]
	[[Category: Homeostasis]]		[[Category: Homeostasis]]
	[[Category: Hpfur]]		[[Category: Hpfur]]
	[[Category: Transcription]]		[[Category: Transcription]]

OCA at 11:11, 13 February 2013

OCA — Wed, 13 Feb 2013 11:11:22 GMT

←Older revision		Revision as of 11:11, 13 February 2013
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	[[Image:2xig.png\|left\|200px]]		[[Image:2xig.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2xig\| PDB=2xig \| SCENE= }}		{{STRUCTURE_2xig\| PDB=2xig \| SCENE= }}

	===THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES===		===THE STRUCTURE OF THE HELICOBACTER PYLORI FERRIC UPTAKE REGULATOR FUR REVEALS THREE FUNCTIONAL METAL BINDING SITES===

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	{{ABSTRACT_PUBMED_21208302}}		{{ABSTRACT_PUBMED_21208302}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21208302~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021208302</ref><references group="xtra"/>
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Bahlawane, C.]]		[[Category: Bahlawane, C.]]
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	[[Category: Terradot, L.]]		[[Category: Terradot, L.]]
	[[Category: Vitale, S.]]		[[Category: Vitale, S.]]
		+	[[Category: Homeostasis]]
		+	[[Category: Hpfur]]
		+	[[Category: Transcription]]

OCA at 08:08, 6 April 2011

OCA — Wed, 06 Apr 2011 08:08:41 GMT

←Older revision		Revision as of 08:08, 6 April 2011
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OCA: Protected "2xig" [edit=sysop:move=sysop]

OCA — Wed, 19 Jan 2011 06:11:17 GMT

Protected "2xig" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:11, 19 January 2011