2y0t - Revision history

OCA at 14:01, 1 February 2024

OCA — Thu, 01 Feb 2024 14:01:36 GMT

←Older revision		Revision as of 14:01, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='2y0t' size='340' side='right'caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2y0t' size='340' side='right'caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arcfl Arcfl~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[2y0q\|2y0q]]~~, [[~~2y20~~\|~~2y20~~]]~~, [[2y21\|2y21]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [https://pdbe.org/2y0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [https://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [https://pdbe.org/2y0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [https://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O28769_ARCFU O28769_ARCFU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arcfl~~]]	+	[[Category: Archaeoglobus fulgidus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ferris~~, H U~~]]	+	[[Category: Ferris HU]]
-	[[Category: Hulko, M]]	+	[[Category: Hulko M]]
-	[[Category: Lupas~~, A N~~]]	+	[[Category: Lupas AN]]
-	[[Category: Zeth, K]]	+	[[Category: Zeth K]]
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Transmembrane signalling~~]]	+

OCA at 12:21, 27 April 2022

OCA — Wed, 27 Apr 2022 12:21:12 GMT

←Older revision		Revision as of 12:21, 27 April 2022
Line 3:		Line 3:
	<StructureSection load='2y0t' size='340' side='right'caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2y0t' size='340' side='right'caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [~~http~~://pdbe.org/2y0t PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [https://pdbe.org/2y0t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [https://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:29, 22 July 2020

OCA — Wed, 22 Jul 2020 12:29:52 GMT

←Older revision		Revision as of 12:29, 22 July 2020
Line 1:		Line 1:

	==The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291F mutant==		==The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291F mutant==
-	<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>	+	<StructureSection load='2y0t' size='340' side='right'caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Arcfl]]		[[Category: Arcfl]]
		+	[[Category: Large Structures]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]
	[[Category: Hulko, M]]		[[Category: Hulko, M]]

OCA at 09:14, 10 October 2018

OCA — Wed, 10 Oct 2018 09:14:22 GMT

←Older revision		Revision as of 09:14, 10 October 2018
Line 3:		Line 3:
	<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arcfl]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]
	[[Category: Hulko, M]]		[[Category: Hulko, M]]

OCA at 02:21, 11 December 2016

OCA — Sun, 11 Dec 2016 02:21:51 GMT

←Older revision		Revision as of 02:21, 11 December 2016
Line 1:		Line 1:

-	==~~THE MECHANISMS OF~~ HAMP-~~MEDIATED SIGNALING IN TRANSMEMBRANE RECEPTORS~~ - ~~THE~~ A291F ~~MUTANT~~==	+	==The mechanisms of HAMP-mediated signaling in transmembrane receptors - the A291F mutant==
	<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Arcfl]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]
	[[Category: Hulko, M]]		[[Category: Hulko, M]]

OCA at 18:25, 4 August 2016

OCA — Thu, 04 Aug 2016 18:25:09 GMT

←Older revision		Revision as of 18:25, 4 August 2016
Line 1:		Line 1:
		+
	==THE MECHANISMS OF HAMP-MEDIATED SIGNALING IN TRANSMEMBRANE RECEPTORS - THE A291F MUTANT==		==THE MECHANISMS OF HAMP-MEDIATED SIGNALING IN TRANSMEMBRANE RECEPTORS - THE A291F MUTANT==
	<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Archaeoglobus_fulgidus Archaeoglobus fulgidus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://pdbe.org/2y0t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y0t ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2y0t" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Archaeoglobus fulgidus~~]]	+	[[Category: Arcfl]]
	[[Category: Ferris, H U]]		[[Category: Ferris, H U]]
	[[Category: Hulko, M]]		[[Category: Hulko, M]]

OCA at 22:57, 3 January 2015

OCA — Sat, 03 Jan 2015 22:57:52 GMT

←Older revision		Revision as of 22:57, 3 January 2015
Line 2:		Line 2:
	<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. <br>	+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y0T FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>
-	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum]</span></td></tr>
-	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 12:
	The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors.,Ferris HU, Dunin-Horkawicz S, Mondejar LG, Hulko M, Hantke K, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M Structure. 2011 Mar 9;19(3):378-85. PMID:21397188<ref>PMID:21397188</ref>		The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors.,Ferris HU, Dunin-Horkawicz S, Mondejar LG, Hulko M, Hantke K, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M Structure. 2011 Mar 9;19(3):378-85. PMID:21397188<ref>PMID:21397188</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 20:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Archaeoglobus fulgidus]]		[[Category: Archaeoglobus fulgidus]]
-	[[Category: Ferris, H U.]]	+	[[Category: Ferris, H U]]
-	[[Category: Hulko, M.]]	+	[[Category: Hulko, M]]
-	[[Category: Lupas, A N.]]	+	[[Category: Lupas, A N]]
-	[[Category: Zeth, K.]]	+	[[Category: Zeth, K]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Transmembrane signalling]]		[[Category: Transmembrane signalling]]

OCA at 07:52, 14 May 2014

OCA — Wed, 14 May 2014 07:52:49 GMT

←Older revision		Revision as of 07:52, 14 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2y0t.~~png~~\|~~left~~\|~~200px~~]]	+	==THE MECHANISMS OF HAMP-MEDIATED SIGNALING IN TRANSMEMBRANE RECEPTORS - THE A291F MUTANT==
		+	<StructureSection load='2y0t' size='340' side='right' caption='[[2y0t]], [[Resolution\|resolution]] 1.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2y0t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y0q\|2y0q]], [[2y20\|2y20]], [[2y21\|2y21]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y0t RCSB], [http://www.ebi.ac.uk/pdbsum/2y0t PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	HAMP domains mediate signal transduction in over 7500 enzyme-coupled receptors represented in all kingdoms of life. The HAMP domain of the putative archaeal receptor Af1503 has a parallel, dimeric, four-helical coiled coil structure, but with unusual core packing, related to canonical packing by concerted axial rotation of the helices. This has led to the gearbox model for signal transduction, whereby the alternate packing modes correspond to signaling states. Here we present structures of a series of Af1503 HAMP variants. We show that substitution of a conserved small side chain within the domain core (A291) for larger residues induces a gradual transition in packing mode, involving both changes in helix rotation and bundle shape, which are most prominent at the C-terminal, output end of the domain. These are correlated with activity and ligand response in vitro and in vivo by incorporating Af1503 HAMP into mycobacterial adenylyl cyclase assay systems.

-	<!--	+	The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors.,Ferris HU, Dunin-Horkawicz S, Mondejar LG, Hulko M, Hantke K, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M Structure. 2011 Mar 9;19(3):378-85. PMID:21397188<ref>PMID:21397188</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2y0t"~~, ~~creates the "~~Structure ~~Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_2y0t\| PDB=2y0t \| SCENE= }}~~	+

-	~~===THE MECHANISMS OF HAMP-MEDIATED SIGNALING IN TRANSMEMBRANE RECEPTORS - THE A291F MUTANT===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_21397188}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21397188 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21397188}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2y0t]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y0T OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021397188<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Archaeoglobus fulgidus]]		[[Category: Archaeoglobus fulgidus]]
	[[Category: Ferris, H U.]]		[[Category: Ferris, H U.]]

OCA at 10:31, 16 November 2011

OCA — Wed, 16 Nov 2011 10:31:33 GMT

←Older revision		Revision as of 10:31, 16 November 2011
Line 1:		Line 1:
-	[[Image:2y0t.~~jpg~~\|left\|200px]]	+	[[Image:2y0t.png\|left\|200px]]

	<!--		<!--
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21397188~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021397188</ref><references group="xtra"/>
	[[Category: Archaeoglobus fulgidus]]		[[Category: Archaeoglobus fulgidus]]
	[[Category: Ferris, H U.]]		[[Category: Ferris, H U.]]
Line 28:		Line 28:
	[[Category: Lupas, A N.]]		[[Category: Lupas, A N.]]
	[[Category: Zeth, K.]]		[[Category: Zeth, K.]]
		+	[[Category: Membrane protein]]
		+	[[Category: Transmembrane signalling]]

OCA: Protected "2y0t" [edit=sysop:move=sysop]

OCA — Wed, 30 Mar 2011 08:09:50 GMT

Protected "2y0t" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:09, 30 March 2011