2y3c - Revision history

OCA at 14:02, 1 February 2024

OCA — Thu, 01 Feb 2024 14:02:02 GMT

←Older revision		Revision as of 14:02, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='2y3c' size='340' side='right'caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2y3c' size='340' side='right'caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"spirillum_dentium"_(miller_1889)_sternberg_1892 "spirillum dentium" (miller 1889) sternberg 1892~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [https://pdbe.org/2y3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [https://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [https://pdbe.org/2y3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [https://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q73KE9_TREDE Q73KE9_TREDE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Coq, J Le~~]]	+	[[Category: Treponema denticola]]
-	[[Category: Ghosh, P]]	+	[[Category: Ghosh P]]
-	[[Category: ~~Periodontal disease]]~~	+	[[Category: Le Coq J]]
-	~~[[Category: Unknown function~~]]	+

OCA at 12:22, 27 April 2022

OCA — Wed, 27 Apr 2022 12:22:21 GMT

←Older revision		Revision as of 12:22, 27 April 2022
Line 3:		Line 3:
	<StructureSection load='2y3c' size='340' side='right'caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2y3c' size='340' side='right'caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"spirillum_dentium"_(miller_1889)_sternberg_1892 "spirillum dentium" (miller 1889) sternberg 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"spirillum_dentium"_(miller_1889)_sternberg_1892 "spirillum dentium" (miller 1889) sternberg 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [~~http~~://pdbe.org/2y3c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [https://pdbe.org/2y3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [https://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:32, 22 July 2020

OCA — Wed, 22 Jul 2020 12:32:44 GMT

←Older revision		Revision as of 12:32, 22 July 2020
Line 1:		Line 1:

	==Treponema denticola variable protein 1==		==Treponema denticola variable protein 1==
-	<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='2y3c' size='340' side='right'caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"spirillum_dentium"_(miller_1889)_sternberg_1892 "spirillum dentium" (miller 1889) sternberg 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"spirillum_dentium"_(miller_1889)_sternberg_1892 "spirillum dentium" (miller 1889) sternberg 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://pdbe.org/2y3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://pdbe.org/2y3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Coq, J Le]]		[[Category: Coq, J Le]]
	[[Category: Ghosh, P]]		[[Category: Ghosh, P]]
	[[Category: Periodontal disease]]		[[Category: Periodontal disease]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 09:35, 10 October 2018

OCA — Wed, 10 Oct 2018 09:35:44 GMT

←Older revision		Revision as of 09:35, 10 October 2018
Line 1:		Line 1:

-	==~~TREPONEMA DENTICOLA VARIABLE PROTEIN~~ 1==	+	==Treponema denticola variable protein 1==
	<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 10:45, 4 August 2016

OCA — Thu, 04 Aug 2016 10:45:00 GMT

←Older revision		Revision as of 10:45, 4 August 2016
Line 1:		Line 1:
		+
	==TREPONEMA DENTICOLA VARIABLE PROTEIN 1==		==TREPONEMA DENTICOLA VARIABLE PROTEIN 1==
	<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Treponema_denticola Treponema denticola~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"spirillum_dentium"_(miller_1889)_sternberg_1892 "spirillum dentium" (miller 1889) sternberg 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://pdbe.org/2y3c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3c ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2y3c" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Treponema denticola]]
	[[Category: Coq, J Le]]		[[Category: Coq, J Le]]
	[[Category: Ghosh, P]]		[[Category: Ghosh, P]]
	[[Category: Periodontal disease]]		[[Category: Periodontal disease]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 08:29, 25 December 2014

OCA — Thu, 25 Dec 2014 08:29:19 GMT

←Older revision		Revision as of 08:29, 25 December 2014
Line 2:		Line 2:
	<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. <br>	+	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3C FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum]</span></td></tr>
-	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 13:
	Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement.,Le Coq J, Ghosh P Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14649-53. Epub 2011 Aug 22. PMID:21873231<ref>PMID:21873231</ref>		Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement.,Le Coq J, Ghosh P Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14649-53. Epub 2011 Aug 22. PMID:21873231<ref>PMID:21873231</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Treponema denticola]]		[[Category: Treponema denticola]]
-	[[Category: Coq, J Le.]]	+	[[Category: Coq, J Le]]
-	[[Category: Ghosh, P.]]	+	[[Category: Ghosh, P]]
	[[Category: Periodontal disease]]		[[Category: Periodontal disease]]
	[[Category: Unknown function]]		[[Category: Unknown function]]

OCA at 07:50, 14 May 2014

OCA — Wed, 14 May 2014 07:50:37 GMT

←Older revision		Revision as of 07:50, 14 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2y3c.~~png~~\|~~left~~\|~~200px~~]]	+	==TREPONEMA DENTICOLA VARIABLE PROTEIN 1==
		+	<StructureSection load='2y3c' size='340' side='right' caption='[[2y3c]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3c RCSB], [http://www.ebi.ac.uk/pdbsum/2y3c PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Anticipatory ligand binding through massive protein sequence variation is rare in biological systems, having been observed only in the vertebrate adaptive immune response and in a phage diversity-generating retroelement (DGR). Earlier work has demonstrated that the prototypical DGR variable protein, major tropism determinant (Mtd), meets the demands of anticipatory ligand binding by novel means through the C-type lectin (CLec) fold. However, because of the low sequence identity among DGR variable proteins, it has remained unclear whether the CLec fold is a general solution for DGRs. We have addressed this problem by determining the structure of a second DGR variable protein, TvpA, from the pathogenic oral spirochete Treponema denticola. Despite its weak sequence identity to Mtd ( approximately 16%), TvpA was found to also have a CLec fold, with predicted variable residues exposed in a ligand-binding site. However, this site in TvpA was markedly more variable than the one in Mtd, reflecting the unprecedented approximate 10(20) potential variability of TvpA. In addition, similarity between TvpA and Mtd with formylglycine-generating enzymes was detected. These results provide strong evidence for the conservation of the formylglycine-generating enzyme-type CLec fold among DGRs as a means of accommodating massive sequence variation.

-	<!--	+	Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement.,Le Coq J, Ghosh P Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14649-53. Epub 2011 Aug 22. PMID:21873231<ref>PMID:21873231</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2y3c"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2y3c\| PDB=2y3c \| SCENE= }}~~	+

-	~~===TREPONEMA DENTICOLA VARIABLE PROTEIN 1===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_21873231}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21873231 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21873231}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2y3c]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021873231<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Treponema denticola]]		[[Category: Treponema denticola]]
	[[Category: Coq, J Le.]]		[[Category: Coq, J Le.]]

OCA at 07:35, 2 November 2011

OCA — Wed, 02 Nov 2011 07:35:47 GMT

←Older revision		Revision as of 07:35, 2 November 2011
Line 1:		Line 1:
-	[[Image:2y3c.~~jpg~~\|left\|200px]]	+	[[Image:2y3c.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===TREPONEMA DENTICOLA VARIABLE PROTEIN 1===		===TREPONEMA DENTICOLA VARIABLE PROTEIN 1===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21873231}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21873231 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21873231}}

	==About this Structure==		==About this Structure==
	[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA].		[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021873231</ref><references group="xtra"/>
	[[Category: Treponema denticola]]		[[Category: Treponema denticola]]
	[[Category: Coq, J Le.]]		[[Category: Coq, J Le.]]

OCA at 06:52, 31 August 2011

OCA — Wed, 31 Aug 2011 06:52:11 GMT

←Older revision		Revision as of 06:52, 31 August 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2y3c.jpg\|left\|200px]]

-	The ~~entry 2y3c~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2y3c", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2y3c\| PDB=2y3c \| SCENE= }}

-	~~Authors: Le Coq, J., Ghosh, P.~~	+	===TREPONEMA DENTICOLA VARIABLE PROTEIN 1===

-	~~Description~~: Treponema denticola ~~variable protein 1~~	+
		+	==About this Structure==
		+	[[2y3c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_denticola Treponema denticola]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3C OCA].
		+	[[Category: Treponema denticola]]
		+	[[Category: Coq, J Le.]]
		+	[[Category: Ghosh, P.]]
		+	[[Category: Periodontal disease]]
		+	[[Category: Unknown function]]

OCA at 07:52, 16 March 2011

OCA — Wed, 16 Mar 2011 07:52:39 GMT

←Older revision		Revision as of 07:52, 16 March 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2y3c is ON HOLD	+	The entry 2y3c is ON HOLD until Paper Publication

	Authors: Le Coq, J., Ghosh, P.		Authors: Le Coq, J., Ghosh, P.

	Description: Treponema denticola variable protein 1		Description: Treponema denticola variable protein 1