2y3m - Revision history

OCA at 14:02, 1 February 2024

OCA — Thu, 01 Feb 2024 14:02:14 GMT

←Older revision		Revision as of 14:02, 1 February 2024
Line 3:		Line 3:
	<StructureSection load='2y3m' size='340' side='right'caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2y3m' size='340' side='right'caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [https://pdbe.org/2y3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [https://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [https://pdbe.org/2y3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [https://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Aggregatibacter actinomycetemcomitans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hogbom, M]]	+	[[Category: Hogbom M]]
-	[[Category: Ihalin, R]]	+	[[Category: Ihalin R]]
-	[[Category: Jaaskelainen, M]]	+	[[Category: Jaaskelainen M]]
-	[[Category: Tarry, M]]	+	[[Category: Tarry M]]
-	[[Category: Tuominen, H]]	+	[[Category: Tuominen H]]
-	~~[[Category: Competence]]~~	+
-	~~[[Category: Dna uptake]]~~	+
-	~~[[Category: Secretin]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 12:22, 27 April 2022

OCA — Wed, 27 Apr 2022 12:22:33 GMT

←Older revision		Revision as of 12:22, 27 April 2022
Line 3:		Line 3:
	<StructureSection load='2y3m' size='340' side='right'caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2y3m' size='340' side='right'caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [~~http~~://pdbe.org/2y3m PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [https://pdbe.org/2y3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [https://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:33, 22 July 2020

OCA — Wed, 22 Jul 2020 12:33:22 GMT

←Older revision		Revision as of 12:33, 22 July 2020
Line 1:		Line 1:

	==Structure of the extra-membranous domain of the secretin HofQ from Actinobacillus actinomycetemcomitans==		==Structure of the extra-membranous domain of the secretin HofQ from Actinobacillus actinomycetemcomitans==
-	<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='2y3m' size='340' side='right'caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://pdbe.org/2y3m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://pdbe.org/2y3m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Hogbom, M]]		[[Category: Hogbom, M]]
	[[Category: Ihalin, R]]		[[Category: Ihalin, R]]

OCA at 09:05, 10 October 2018

OCA — Wed, 10 Oct 2018 09:05:46 GMT

←Older revision		Revision as of 09:05, 10 October 2018
Line 1:		Line 1:

-	==~~STRUCTURE OF THE EXTRA~~-~~MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS~~==	+	==Structure of the extra-membranous domain of the secretin HofQ from Actinobacillus actinomycetemcomitans==
	<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 01:38, 5 August 2016

OCA — Fri, 05 Aug 2016 01:38:44 GMT

←Older revision		Revision as of 01:38, 5 August 2016
Line 1:		Line 1:
		+
	==STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS==		==STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS==
	<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_acetinomycetum_comitans"_(sic)_(klinger_1912)_colebrook_1920 "bacterium acetinomycetum comitans" (sic) (klinger 1912) colebrook 1920]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://pdbe.org/2y3m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y3m ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2y3m" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Aggregatibacter actinomycetemcomitans]]
	[[Category: Hogbom, M]]		[[Category: Hogbom, M]]
	[[Category: Ihalin, R]]		[[Category: Ihalin, R]]

OCA at 22:49, 3 January 2015

OCA — Sat, 03 Jan 2015 22:49:59 GMT

←Older revision		Revision as of 22:49, 3 January 2015
Line 2:		Line 2:
	<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. <br>	+	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y3M FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene~~><br>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum]</span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 12:
	The extra-membranous domains of the competence protein HofQ show DNA binding, flexibility and a shared fold with type I KH domains.,Tarry M, Jaaskelainen M, Paino A, Tuominen H, Ihalin R, Hogbom M J Mol Biol. 2011 Jun 17;409(4):642-53. Epub 2011 Apr 20. PMID:21530539<ref>PMID:21530539</ref>		The extra-membranous domains of the competence protein HofQ show DNA binding, flexibility and a shared fold with type I KH domains.,Tarry M, Jaaskelainen M, Paino A, Tuominen H, Ihalin R, Hogbom M J Mol Biol. 2011 Jun 17;409(4):642-53. Epub 2011 Apr 20. PMID:21530539<ref>PMID:21530539</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 20:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Aggregatibacter actinomycetemcomitans]]		[[Category: Aggregatibacter actinomycetemcomitans]]
-	[[Category: Hogbom, M.]]	+	[[Category: Hogbom, M]]
-	[[Category: Ihalin, R.]]	+	[[Category: Ihalin, R]]
-	[[Category: Jaaskelainen, M.]]	+	[[Category: Jaaskelainen, M]]
-	[[Category: Tarry, M.]]	+	[[Category: Tarry, M]]
-	[[Category: Tuominen, H.]]	+	[[Category: Tuominen, H]]
	[[Category: Competence]]		[[Category: Competence]]
	[[Category: Dna uptake]]		[[Category: Dna uptake]]
	[[Category: Secretin]]		[[Category: Secretin]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 07:48, 14 May 2014

OCA — Wed, 14 May 2014 07:48:51 GMT

←Older revision		Revision as of 07:48, 14 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2y3m.~~png~~\|~~left\|200px~~]]	+	==STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS==
		+	<StructureSection load='2y3m' size='340' side='right' caption='[[2y3m]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y3m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y3m RCSB], [http://www.ebi.ac.uk/pdbsum/2y3m PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Secretins form large oligomeric assemblies in the membrane that control both macromolecular secretion and uptake. Several Pasteurellaceae are naturally competent for transformation, but the mechanism for DNA assimilation is largely unknown. In Haemophilus influenzae, the secretin ComE has been demonstrated to be essential for DNA uptake. In closely related Aggregatibacter actinomycetemcomitans, an opportunistic pathogen in periodontitis, the ComE homolog HofQ is believed to be the outer membrane DNA translocase. Here, we report the structure of the extra-membranous domains of HofQ at 2.3 A resolution by X-ray crystallography. We also show that the extra-membranous domains of HofQ are capable of DNA binding. The structure reveals two secretin-like folds, the first of which is formed by means of a domain swap. The second domain displays extensive structural similarity to K homology (KH) domains, including the presence of a GxxG motif, which is essential for the nucleotide-binding function of KH domains, suggesting a possible mechanism for DNA binding by HofQ. The data indicate a direct involvement in DNA acquisition and provide insight into the molecular basis for natural competence.

-	<!--	+	The extra-membranous domains of the competence protein HofQ show DNA binding, flexibility and a shared fold with type I KH domains.,Tarry M, Jaaskelainen M, Paino A, Tuominen H, Ihalin R, Hogbom M J Mol Biol. 2011 Jun 17;409(4):642-53. Epub 2011 Apr 20. PMID:21530539<ref>PMID:21530539</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2y3m"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2y3m\| PDB=2y3m \| SCENE= }}~~	+

-	~~===STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_21530539}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21530539 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21530539}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2y3m]] is a 2 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021530539<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Aggregatibacter actinomycetemcomitans]]		[[Category: Aggregatibacter actinomycetemcomitans]]
	[[Category: Hogbom, M.]]		[[Category: Hogbom, M.]]

OCA at 05:51, 31 August 2011

OCA — Wed, 31 Aug 2011 05:51:44 GMT

←Older revision		Revision as of 05:51, 31 August 2011
Line 11:		Line 11:
	===STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS===		===STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21530539}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21530539 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21530539}}

	==About this Structure==		==About this Structure==
	[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA].		[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021530539</ref><references group="xtra"/>
	[[Category: Aggregatibacter actinomycetemcomitans]]		[[Category: Aggregatibacter actinomycetemcomitans]]
	[[Category: Hogbom, M.]]		[[Category: Hogbom, M.]]

OCA at 15:55, 22 June 2011

OCA — Wed, 22 Jun 2011 15:55:25 GMT

←Older revision		Revision as of 15:55, 22 June 2011
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-	[[Image:2y3m.~~jpg~~\|left\|200px]]	+	[[Image:2y3m.png\|left\|200px]]

	<!--		<!--
Line 20:		Line 20:
	[[Category: Tarry, M.]]		[[Category: Tarry, M.]]
	[[Category: Tuominen, H.]]		[[Category: Tuominen, H.]]
		+	[[Category: Competence]]
		+	[[Category: Dna uptake]]
		+	[[Category: Secretin]]
		+	[[Category: Transport protein]]

OCA at 07:21, 27 April 2011

OCA — Wed, 27 Apr 2011 07:21:14 GMT

←Older revision		Revision as of 07:21, 27 April 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2y3m.jpg\|left\|200px]]

-	The ~~entry 2y3m~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2y3m", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2y3m\| PDB=2y3m \| SCENE= }}

-	~~Authors: Tarry, M., Jaaskelainen, M., Tuominen, H., Ihalin, R., Hogbom, M.~~	+	===STRUCTURE OF THE EXTRA-MEMBRANOUS DOMAIN OF THE SECRETIN HOFQ FROM ACTINOBACILLUS ACTINOMYCETEMCOMITANS===

-	~~Description:~~ Structure ~~of the extra-membranous domain of the secretin HofQ~~ from ~~Actinobacillus~~ actinomycetemcomitans	+
		+	==About this Structure==
		+	[[2y3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aggregatibacter_actinomycetemcomitans Aggregatibacter actinomycetemcomitans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y3M OCA].
		+	[[Category: Aggregatibacter actinomycetemcomitans]]
		+	[[Category: Hogbom, M.]]
		+	[[Category: Ihalin, R.]]
		+	[[Category: Jaaskelainen, M.]]
		+	[[Category: Tarry, M.]]
		+	[[Category: Tuominen, H.]]