2y7y - Revision history

OCA at 10:47, 20 December 2023

OCA — Wed, 20 Dec 2023 10:47:37 GMT

←Older revision		Revision as of 10:47, 20 December 2023
Line 3:		Line 3:
	<StructureSection load='2y7y' size='340' side='right'caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2y7y' size='340' side='right'caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Aplca Aplca~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[2wn9\|2wn9]]~~, [[~~2w8f~~\|~~2w8f~~]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</div></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.895Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [https://pdbe.org/2y7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [https://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [https://pdbe.org/2y7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [https://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8WSF8_APLCA Q8WSF8_APLCA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aplca~~]]	+	[[Category: Aplysia californica]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Akdemir, A]]	+	[[Category: Akdemir A]]
-	[[Category: Bertrand, D]]	+	[[Category: Bertrand D]]
-	[[Category: Bertrand, S]]	+	[[Category: Bertrand S]]
-	[[Category: ~~Elk, R van]]~~	+	[[Category: De Esch IJ]]
-	~~[[Category:~~ Esch~~, I J.De~~]]	+	[[Category: Jongejan A]]
-	[[Category: Jongejan, A]]	+	[[Category: Leurs R]]
-	[[Category: Leurs, R]]	+	[[Category: Perrakis A]]
-	[[Category: Perrakis, A]]	+	[[Category: Sixma TK]]
-	[[Category: Sixma~~, T K~~]]	+	[[Category: Smit AB]]
-	[[Category: Smit~~, A B~~]]	+	[[Category: Ulens C]]
-	[[Category: Ulens, C]]	+	[[Category: Van Elk R]]
-	[[Category: ~~Amidation]]~~	+
-	~~[[Category: Conotoxin]]~~	+
-	~~[[Category: Receptor]]~~	+
-	~~[[Category: Secreted~~]]	+

OCA at 12:24, 27 April 2022

OCA — Wed, 27 Apr 2022 12:24:49 GMT

←Older revision		Revision as of 12:24, 27 April 2022
Line 3:		Line 3:
	<StructureSection load='2y7y' size='340' side='right'caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2y7y' size='340' side='right'caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Aplca Aplca]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplca Aplca]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [~~http~~://pdbe.org/2y7y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [https://pdbe.org/2y7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [https://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:38, 22 July 2020

OCA — Wed, 22 Jul 2020 12:38:38 GMT

←Older revision		Revision as of 12:38, 22 July 2020
Line 1:		Line 1:

	==APLYSIA CALIFORNICA ACHBP IN APO STATE==		==APLYSIA CALIFORNICA ACHBP IN APO STATE==
-	<StructureSection load='2y7y' size='340' side='right' caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2y7y' size='340' side='right'caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [http://pdbe.org/2y7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [http://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [http://pdbe.org/2y7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [http://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 18:

	==See Also==		==See Also==
-	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]	+	*[[Acetylcholine binding protein 3D structures\|Acetylcholine binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Aplca]]		[[Category: Aplca]]
		+	[[Category: Large Structures]]
	[[Category: Akdemir, A]]		[[Category: Akdemir, A]]
	[[Category: Bertrand, D]]		[[Category: Bertrand, D]]

OCA at 09:41, 10 October 2018

OCA — Wed, 10 Oct 2018 09:41:45 GMT

←Older revision		Revision as of 09:41, 10 October 2018
Line 27:		Line 27:
	[[Category: Bertrand, D]]		[[Category: Bertrand, D]]
	[[Category: Bertrand, S]]		[[Category: Bertrand, S]]
-	[[Category: Elk, R ~~Van~~]]	+	[[Category: Elk, R van]]
	[[Category: Esch, I J.De]]		[[Category: Esch, I J.De]]
	[[Category: Jongejan, A]]		[[Category: Jongejan, A]]

OCA at 17:38, 11 August 2016

OCA — Thu, 11 Aug 2016 17:38:46 GMT

←Older revision		Revision as of 17:38, 11 August 2016
Line 1:		Line 1:
		+
	==APLYSIA CALIFORNICA ACHBP IN APO STATE==		==APLYSIA CALIFORNICA ACHBP IN APO STATE==
	<StructureSection load='2y7y' size='340' side='right' caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2y7y' size='340' side='right' caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Aplysia_californica Aplysia californica~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplca Aplca]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [http://www.ebi.ac.uk/pdbsum/2y7y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [http://pdbe.org/2y7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [http://www.ebi.ac.uk/pdbsum/2y7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7y ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2y7y" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aplysia californica~~]]	+	[[Category: Aplca]]
	[[Category: Akdemir, A]]		[[Category: Akdemir, A]]
	[[Category: Bertrand, D]]		[[Category: Bertrand, D]]

OCA at 08:25, 25 January 2015

OCA — Sun, 25 Jan 2015 08:25:48 GMT

←Older revision		Revision as of 08:25, 25 January 2015
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Aplysia californica]]		[[Category: Aplysia californica]]
-	[[Category: Akdemir, A.]]	+	[[Category: Akdemir, A]]
-	[[Category: Bertrand, D.]]	+	[[Category: Bertrand, D]]
-	[[Category: Bertrand, S.]]	+	[[Category: Bertrand, S]]
-	[[Category: Elk, R Van.]]	+	[[Category: Elk, R Van]]
-	[[Category: Esch, I J.De.]]	+	[[Category: Esch, I J.De]]
-	[[Category: Jongejan, A.]]	+	[[Category: Jongejan, A]]
-	[[Category: Leurs, R.]]	+	[[Category: Leurs, R]]
-	[[Category: Perrakis, A.]]	+	[[Category: Perrakis, A]]
-	[[Category: Sixma, T K.]]	+	[[Category: Sixma, T K]]
-	[[Category: Smit, A B.]]	+	[[Category: Smit, A B]]
-	[[Category: Ulens, C.]]	+	[[Category: Ulens, C]]
	[[Category: Amidation]]		[[Category: Amidation]]
	[[Category: Conotoxin]]		[[Category: Conotoxin]]
	[[Category: Receptor]]		[[Category: Receptor]]
	[[Category: Secreted]]		[[Category: Secreted]]

OCA at 13:26, 22 October 2014

OCA — Wed, 22 Oct 2014 13:26:58 GMT

←Older revision		Revision as of 13:26, 22 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2y7y.~~png~~\|~~left~~\|~~200px~~]]	+	==APLYSIA CALIFORNICA ACHBP IN APO STATE==
		+	<StructureSection load='2y7y' size='340' side='right' caption='[[2y7y]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y7Y FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wn9\|2wn9]], [[2w8f\|2w8f]], [[2y58\|2y58]], [[2xz6\|2xz6]], [[2byp\|2byp]], [[2c9t\|2c9t]], [[2xyt\|2xyt]], [[2byq\|2byq]], [[2w8g\|2w8g]], [[2x00\|2x00]], [[2uz6\|2uz6]], [[2y57\|2y57]], [[2wnl\|2wnl]], [[2br8\|2br8]], [[2br7\|2br7]], [[2xys\|2xys]], [[2xnv\|2xnv]], [[2byr\|2byr]], [[2xz5\|2xz5]], [[2byn\|2byn]], [[2bys\|2bys]], [[2y54\|2y54]], [[2xnt\|2xnt]], [[2wnj\|2wnj]], [[2wzy\|2wzy]], [[2wnc\|2wnc]], [[2xnu\|2xnu]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y7y RCSB], [http://www.ebi.ac.uk/pdbsum/2y7y PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Acetylcholine binding protein (AChBP) is widely considered as a functional and structural homologue of the ligand binding domain of Cys-loop receptors. We report the use of AChBP as template to identify ligands for the nicotinic receptors (nAChRs). An in silico screening protocol was set up and applied to crystal structures of AChBP. Several ligands containing a dibenzosuberyl moiety were identified and shown to bind with high affinity to AChBP and alpha7 nAChRs. Two high affinity ligands were cocrystallized with AChBP, revealing the binding mode in the orthosteric site. Functional studies revealed that these two ligands caused inhibition of the alpha7, alpha4beta2, and 5HT(3) receptors. The noncompetive blockade of the receptors suggests that these compounds act by steric hindrance of the channel. The analysis of the dual binding mode of these dibenzosuberyl-containing compounds can lead to better understanding of the complex mode of action of similar tricyclic ligands on Cys-loop receptors.

-	~~{{STRUCTURE_2y7y\| PDB=2y7y \| SCENE= }}~~	+	Use of Acetylcholine Binding Protein in the Search for Novel alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis (dagger).,Ulens C, Akdemir A, Jongejan A, van Elk R, Bertrand S, Perrakis A, Leurs R, Smit AB, Sixma TK, Bertrand D, de Esch IJ J Med Chem. 2009 Mar 30. PMID:19331415<ref>PMID:19331415</ref>

-	~~===APLYSIA CALIFORNICA ACHBP IN APO STATE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19331415}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2y7y]] is~~ a ~~5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes~~ the ~~now removed PDB entry [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA].~~	+

	==See Also==		==See Also==
	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]		*[[Acetylcholine binding protein\|Acetylcholine binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019331415<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Aplysia californica]]		[[Category: Aplysia californica]]
	[[Category: Akdemir, A.]]		[[Category: Akdemir, A.]]

OCA at 21:30, 20 October 2012

OCA — Sat, 20 Oct 2012 21:30:00 GMT

←Older revision		Revision as of 21:30, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2y7y]] is a 5 chain structure ~~of [[Acetylcholine binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA].	+	[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA].

	==See Also==		==See Also==

OCA at 13:26, 27 July 2012

OCA — Fri, 27 Jul 2012 13:26:37 GMT

←Older revision		Revision as of 13:26, 27 July 2012
Line 1:		Line 1:
-	[[Image:2y7y.~~jpg~~\|left\|200px]]	+	[[Image:2y7y.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2y7y", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2y7y\| PDB=2y7y \| SCENE= }}		{{STRUCTURE_2y7y\| PDB=2y7y \| SCENE= }}

	===APLYSIA CALIFORNICA ACHBP IN APO STATE===		===APLYSIA CALIFORNICA ACHBP IN APO STATE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19331415}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19331415 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19331415}}		{{ABSTRACT_PUBMED_19331415}}

	==About this Structure==		==About this Structure==
-	[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA].	+	[[2y7y]] is a 5 chain structure of [[Acetylcholine binding protein]] with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA].
		+
		+	==See Also==
		+	*[[Acetylcholine binding protein\|Acetylcholine binding protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19331415~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019331415</ref><references group="xtra"/>
	[[Category: Aplysia californica]]		[[Category: Aplysia californica]]
	[[Category: Akdemir, A.]]		[[Category: Akdemir, A.]]
Line 35:		Line 27:
	[[Category: Smit, A B.]]		[[Category: Smit, A B.]]
	[[Category: Ulens, C.]]		[[Category: Ulens, C.]]
		+	[[Category: Amidation]]
		+	[[Category: Conotoxin]]
		+	[[Category: Receptor]]
		+	[[Category: Secreted]]

OCA at 07:02, 23 March 2011

OCA — Wed, 23 Mar 2011 07:02:24 GMT

←Older revision		Revision as of 07:02, 23 March 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2y7y.jpg\|left\|200px]]

-	The ~~entry 2y7y~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2y7y", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2y7y\| PDB=2y7y \| SCENE= }}

-	~~Authors: Ulens, C., Akdemir, A., Jongejan, A., van Elk, R., Bertrand, S., Perrakis, A., Leurs, R., Smit, A.B., Sixma, T.K., Bertrand, D., De Esch, I.J.~~	+	===APLYSIA CALIFORNICA ACHBP IN APO STATE===

-	~~Description~~: ~~APLYSIA CALIFORNICA ACHBP IN APO STATE~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19331415}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19331415 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19331415}}
		+
		+	==About this Structure==
		+	[[2y7y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2w8e 2w8e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7Y OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19331415</ref><references group="xtra"/>
		+	[[Category: Aplysia californica]]
		+	[[Category: Akdemir, A.]]
		+	[[Category: Bertrand, D.]]
		+	[[Category: Bertrand, S.]]
		+	[[Category: Elk, R Van.]]
		+	[[Category: Esch, I J.De.]]
		+	[[Category: Jongejan, A.]]
		+	[[Category: Leurs, R.]]
		+	[[Category: Perrakis, A.]]
		+	[[Category: Sixma, T K.]]
		+	[[Category: Smit, A B.]]
		+	[[Category: Ulens, C.]]