2y89 - Revision history

OCA at 08:10, 23 August 2023

OCA — Wed, 23 Aug 2023 08:10:26 GMT

←Older revision		Revision as of 08:10, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='2y89' size='340' side='right'caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2y89' size='340' side='right'caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Myctu Myctu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2y85\|2y85]], [[2y88\|2y88]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [https://pdbe.org/2y89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [https://www.ebi.ac.uk/pdbsum/2y89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y89 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [https://pdbe.org/2y89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [https://www.ebi.ac.uk/pdbsum/2y89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y89 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU]] Involved in both the histidine and tryptophan biosynthetic pathways.	+	[https://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU] Involved in both the histidine and tryptophan biosynthetic pathways.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Myctu~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: Due~~, A V~~]]	+	[[Category: Due AV]]
-	[[Category: Geerlof, A]]	+	[[Category: Geerlof A]]
-	[[Category: Kuper, J]]	+	[[Category: Kuper J]]
-	[[Category: Wilmanns, M]]	+	[[Category: Wilmanns M]]
-	~~[[Category: Aromatic amino acid biosynthesis]]~~	+
-	~~[[Category: Histidine biosynthesis]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Tim barrel]]~~	+
-	~~[[Category: Tryptophan biosynthesis~~]]	+

OCA at 15:01, 17 November 2021

OCA — Wed, 17 Nov 2021 15:01:44 GMT

←Older revision		Revision as of 15:01, 17 November 2021
Line 3:		Line 3:
	<StructureSection load='2y89' size='340' side='right'caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2y89' size='340' side='right'caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y85\|2y85]], [[2y88\|2y88]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2y85\|2y85]], [[2y88\|2y88]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [~~http~~://pdbe.org/2y89 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2y89 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2y89 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [https://pdbe.org/2y89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [https://www.ebi.ac.uk/pdbsum/2y89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y89 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU]] Involved in both the histidine and tryptophan biosynthetic pathways.	+	[[https://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU]] Involved in both the histidine and tryptophan biosynthetic pathways.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 11:04, 17 July 2019

OCA — Wed, 17 Jul 2019 11:04:07 GMT

←Older revision		Revision as of 11:04, 17 July 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)==		==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)==
-	<StructureSection load='2y89' size='340' side='right' caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2y89' size='340' side='right'caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Myctu]]		[[Category: Myctu]]
	[[Category: Due, A V]]		[[Category: Due, A V]]

OCA at 19:29, 5 August 2016

OCA — Fri, 05 Aug 2016 19:29:49 GMT

←Older revision		Revision as of 19:29, 5 August 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)==		==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)==
	<StructureSection load='2y89' size='340' side='right' caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2y89' size='340' side='right' caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_tuberculosis Mycobacterium tuberculosis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y85\|2y85]], [[2y88\|2y88]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y85\|2y85]], [[2y88\|2y88]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [http://www.ebi.ac.uk/pdbsum/2y89 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [http://pdbe.org/2y89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [http://www.ebi.ac.uk/pdbsum/2y89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y89 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2y89" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mycobacterium tuberculosis~~]]	+	[[Category: Myctu]]
	[[Category: Due, A V]]		[[Category: Due, A V]]
	[[Category: Geerlof, A]]		[[Category: Geerlof, A]]

OCA at 05:13, 25 December 2014

OCA — Thu, 25 Dec 2014 05:13:53 GMT

←Older revision		Revision as of 05:13, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [http://www.ebi.ac.uk/pdbsum/2y89 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [http://www.ebi.ac.uk/pdbsum/2y89 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HIS4_MYCTU HIS4_MYCTU]] Involved in both the histidine and tryptophan biosynthetic pathways.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 08:22, 12 November 2014

OCA — Wed, 12 Nov 2014 08:22:17 GMT

←Older revision		Revision as of 08:22, 12 November 2014
Line 1:		Line 1:
-	[[~~Image:~~2y89.~~png~~\|~~left~~\|~~200px~~]]	+	==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)==
		+	<StructureSection load='2y89' size='340' side='right' caption='[[2y89]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2y89]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y89 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2y85\|2y85]], [[2y88\|2y88]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y89 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y89 RCSB], [http://www.ebi.ac.uk/pdbsum/2y89 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In histidine and tryptophan biosynthesis, two related isomerization reactions are generally catalyzed by two specific single-substrate enzymes (HisA and TrpF), sharing a similar (beta/alpha)(8)-barrel scaffold. However, in some actinobacteria, one of the two encoding genes (trpF) is missing and the two reactions are instead catalyzed by one bisubstrate enzyme (PriA). To unravel the unknown mechanism of bisubstrate specificity, we used the Mycobacterium tuberculosis PriA enzyme as a model. Comparative structural analysis of the active site of the enzyme showed that PriA undergoes a reaction-specific and substrate-induced metamorphosis of the active site architecture, demonstrating its unique ability to essentially form two different substrate-specific actives sites. Furthermore, we found that one of the two catalytic residues in PriA, which are identical in both isomerization reactions, is recruited by a substrate-dependent mechanism into the active site to allow its involvement in catalysis. Comparison of the structural data from PriA with one of the two single-substrate enzymes (TrpF) revealed substantial differences in the active site architecture, suggesting independent evolution. To support these observations, we identified six small molecule compounds that inhibited both PriA-catalyzed isomerization reactions but had no effect on TrpF activity. Our data demonstrate an opportunity for organism-specific inhibition of enzymatic catalysis by taking advantage of the distinct ability for bisubstrate catalysis in the M. tuberculosis enzyme.

-	~~{{STRUCTURE_2y89\| PDB=2y89 \| SCENE= }}~~	+	Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis.,Due AV, Kuper J, Geerlof A, Kries JP, Wilmanns M Proc Natl Acad Sci U S A. 2011 Feb 14. PMID:21321225<ref>PMID:21321225</ref>

-	~~===CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21321225}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2y89]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021321225<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
-	[[Category: Due, A V.]]	+	[[Category: Due, A V]]
-	[[Category: Geerlof, A.]]	+	[[Category: Geerlof, A]]
-	[[Category: Kuper, J.]]	+	[[Category: Kuper, J]]
-	[[Category: Wilmanns, M.]]	+	[[Category: Wilmanns, M]]
	[[Category: Aromatic amino acid biosynthesis]]		[[Category: Aromatic amino acid biosynthesis]]
	[[Category: Histidine biosynthesis]]		[[Category: Histidine biosynthesis]]

OCA at 13:46, 6 February 2013

OCA — Wed, 06 Feb 2013 13:46:18 GMT

←Older revision		Revision as of 13:46, 6 February 2013
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	[[Image:2y89.png\|left\|200px]]		[[Image:2y89.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2y89\| PDB=2y89 \| SCENE= }}		{{STRUCTURE_2y89\| PDB=2y89 \| SCENE= }}

	===CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)===		===CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)===

-
-	<!--
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-	(as it appears on PubMed at http://www.pubmed.gov), where 21321225 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_21321225}}		{{ABSTRACT_PUBMED_21321225}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21321225~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021321225</ref><references group="xtra"/>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Due, A V.]]		[[Category: Due, A V.]]
Line 28:		Line 17:
	[[Category: Kuper, J.]]		[[Category: Kuper, J.]]
	[[Category: Wilmanns, M.]]		[[Category: Wilmanns, M.]]
		+	[[Category: Aromatic amino acid biosynthesis]]
		+	[[Category: Histidine biosynthesis]]
		+	[[Category: Isomerase]]
		+	[[Category: Tim barrel]]
		+	[[Category: Tryptophan biosynthesis]]

OCA at 07:48, 16 March 2011

OCA — Wed, 16 Mar 2011 07:48:54 GMT

←Older revision		Revision as of 07:48, 16 March 2011
Line 1:		Line 1:
-	[[Image:2y89.~~jpg~~\|left\|200px]]	+	[[Image:2y89.png\|left\|200px]]

	<!--		<!--

OCA at 06:59, 2 March 2011

OCA — Wed, 02 Mar 2011 06:59:55 GMT

←Older revision		Revision as of 06:59, 2 March 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2y89.jpg\|left\|200px]]

-	The ~~entry 2y89~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2y89", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2y89\| PDB=2y89 \| SCENE= }}

-	~~Authors: DUE,~~ A~~.V., KUPER, J., GEERLOF, A., WILMANNS, M.~~	+	===CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)===

-	~~Description: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A~~ (~~VARIANT D11N~~)	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21321225}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21321225 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21321225}}
		+
		+	==About this Structure==
		+	[[2y89]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y89 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21321225</ref><references group="xtra"/>
		+	[[Category: Mycobacterium tuberculosis]]
		+	[[Category: Due, A V.]]
		+	[[Category: Geerlof, A.]]
		+	[[Category: Kuper, J.]]
		+	[[Category: Wilmanns, M.]]

OCA at 05:12, 16 February 2011

OCA — Wed, 16 Feb 2011 05:12:00 GMT

←Older revision		Revision as of 05:12, 16 February 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2y89 is ON HOLD until ~~sometime in the future~~	+	The entry 2y89 is ON HOLD until Paper Publication

	Authors: DUE, A.V., KUPER, J., GEERLOF, A., WILMANNS, M.		Authors: DUE, A.V., KUPER, J., GEERLOF, A., WILMANNS, M.

	Description: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)		Description: CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)