2yhq - Revision history

OCA: Redirecting to 4v5v

OCA — Wed, 10 Dec 2014 15:18:45 GMT

Redirecting to 4v5v

←Older revision		Revision as of 15:18, 10 December 2014
Line 1:		Line 1:
-	~~==Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form==~~	+	#REDIRECT [[4v5v]] This PDB entry is obsolete and replaced by 4v5v
-	~~<StructureSection load='2yhq' size='340' side='right' caption='~~[[~~2yhq]], [[Resolution\|resolution]] 3.60Å' scene=''>~~	+
-	~~== Structural highlights ==~~	+
-	~~<table><tr><td colspan='2'>[[2yhq~~]] is ~~a 22 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]~~ and [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus Human respiratory syncytial virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHQ OCA]. <br>	+
-	~~</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yhp\|2yhp]]</td></tr>~~	+
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yhq RCSB], [http://www.ebi.ac.uk/pdbsum/2yhq PDBsum]</span></td></tr>	+
-	~~<table>~~	+
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Respiratory syncytial virus (RSV) is a frequent cause of respiratory illness in infants, but there is currently no vaccine nor effective drug treatment against this virus. The RSV RNA genome is encapsidated and protected by a nucleocapsid protein; this RNA-nucleocapsid complex serves as a template for viral replication. Interest in the nucleocapsid protein has increased owing to its recent identification as the target site for novel anti-RSV compounds. The crystal structure of human respiratory syncytial virus nucleocapsid (HRSVN) was determined to 3.6 A resolution from two crystal forms belonging to space groups P2(1)2(1)2(1) and P1, with one and four decameric rings per asymmetric unit, respectively. In contrast to a previous structure of HRSVN, the addition of phosphoprotein was not required to obtain diffraction-quality crystals. The HRSVN structures reported here, although similar to the recently published structure, present different molecular packing which may have some biological implications. The positions of the monomers are slightly shifted in the decamer, confirming the adaptability of the ring structure. The details of the inter-ring contacts in one crystal form revealed here suggest a basis for helical packing and that the stabilization of native HRSVN is via mainly ionic interactions.	+
-		+
-	Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.,El Omari K, Dhaliwal B, Ren J, Abrescia NG, Lockyer M, Powell KL, Hawkins AR, Stammers DK Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt, 10):1179-83. Epub 2011 Sep 24. PMID:22102022<ref>PMID:22102022</ref>	+
-		+
-	~~From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
-	~~__TOC__~~	+
-	~~</StructureSection>~~	+
-	~~[[Category: Escherichia coli]]~~	+
-	~~[[Category: Human respiratory syncytial virus]]~~	+
-	~~[[Category: Abrescia, N G.A.]]~~	+
-	~~[[Category: Dhaliwal, B.]]~~	+
-	~~[[Category: Hawkins, A R.]]~~	+
-	~~[[Category: Lockyer, M.]]~~	+
-	~~[[Category: Omari, K El.]]~~	+
-	~~[[Category: Powell, K L.]]~~	+
-	~~[[Category: Ren, J.]]~~	+
-	~~[[Category: Stammers, D K.]]~~	+
-	~~[[Category: Viral protein-rna complex]]~~	+

OCA at 07:40, 14 May 2014

OCA — Wed, 14 May 2014 07:40:59 GMT

←Older revision		Revision as of 07:40, 14 May 2014
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-	[[~~Image:~~2yhq.~~png~~\|~~left~~\|~~200px~~]]	+	==Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form==
		+	<StructureSection load='2yhq' size='340' side='right' caption='[[2yhq]], [[Resolution\|resolution]] 3.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2yhq]] is a 22 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus Human respiratory syncytial virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHQ OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yhp\|2yhp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yhq RCSB], [http://www.ebi.ac.uk/pdbsum/2yhq PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Respiratory syncytial virus (RSV) is a frequent cause of respiratory illness in infants, but there is currently no vaccine nor effective drug treatment against this virus. The RSV RNA genome is encapsidated and protected by a nucleocapsid protein; this RNA-nucleocapsid complex serves as a template for viral replication. Interest in the nucleocapsid protein has increased owing to its recent identification as the target site for novel anti-RSV compounds. The crystal structure of human respiratory syncytial virus nucleocapsid (HRSVN) was determined to 3.6 A resolution from two crystal forms belonging to space groups P2(1)2(1)2(1) and P1, with one and four decameric rings per asymmetric unit, respectively. In contrast to a previous structure of HRSVN, the addition of phosphoprotein was not required to obtain diffraction-quality crystals. The HRSVN structures reported here, although similar to the recently published structure, present different molecular packing which may have some biological implications. The positions of the monomers are slightly shifted in the decamer, confirming the adaptability of the ring structure. The details of the inter-ring contacts in one crystal form revealed here suggest a basis for helical packing and that the stabilization of native HRSVN is via mainly ionic interactions.

-	~~<!--~~	+	Structures of respiratory syncytial virus nucleocapsid protein from two crystal forms: details of potential packing interactions in the native helical form.,El Omari K, Dhaliwal B, Ren J, Abrescia NG, Lockyer M, Powell KL, Hawkins AR, Stammers DK Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt, 10):1179-83. Epub 2011 Sep 24. PMID:22102022<ref>PMID:22102022</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2yhq"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2yhq\| PDB=2yhq \| SCENE= }}~~	+

-	~~===Structure~~ of ~~respiratory syncytial virus nucleocapsid protein, P1 crystal form===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22102022}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22102022 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22102022}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2yhq]] is a 22 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus Human respiratory syncytial virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHQ OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022102022<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Human respiratory syncytial virus]]		[[Category: Human respiratory syncytial virus]]

OCA at 07:25, 1 February 2012

OCA — Wed, 01 Feb 2012 07:25:28 GMT

←Older revision		Revision as of 07:25, 1 February 2012
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-	[[Image:2yhq.~~jpg~~\|left\|200px]]	+	[[Image:2yhq.png\|left\|200px]]

	<!--		<!--

OCA at 06:29, 25 January 2012

OCA — Wed, 25 Jan 2012 06:29:09 GMT

←Older revision		Revision as of 06:29, 25 January 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2yhq.jpg\|left\|200px]]

-	The ~~entry 2yhq~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2yhq", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2yhq\| PDB=2yhq \| SCENE= }}

-	~~Authors: El Omari~~, ~~K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.~~	+	===Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form===

-	~~Description~~: Structure of respiratory syncytial virus ~~nucleocapsid protein~~, ~~P1 crystal form~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22102022}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22102022 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22102022}}
		+
		+	==About this Structure==
		+	[[2yhq]] is a 22 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Human_respiratory_syncytial_virus Human respiratory syncytial virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHQ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022102022</ref><references group="xtra"/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Human respiratory syncytial virus]]
		+	[[Category: Abrescia, N G.A.]]
		+	[[Category: Dhaliwal, B.]]
		+	[[Category: Hawkins, A R.]]
		+	[[Category: Lockyer, M.]]
		+	[[Category: Omari, K El.]]
		+	[[Category: Powell, K L.]]
		+	[[Category: Ren, J.]]
		+	[[Category: Stammers, D K.]]
		+	[[Category: Viral protein-rna complex]]

OCA at 04:39, 8 June 2011

OCA — Wed, 08 Jun 2011 04:39:35 GMT

←Older revision		Revision as of 04:39, 8 June 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2yhq is ON HOLD ~~until sometime in the future~~	+	The entry 2yhq is ON HOLD

	Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.		Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.

	Description: Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form		Description: Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form

OCA at 04:55, 25 May 2011

OCA — Wed, 25 May 2011 04:55:05 GMT

←Older revision		Revision as of 04:55, 25 May 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2yhq is ON HOLD	+	The entry 2yhq is ON HOLD until sometime in the future

	Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.		Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.

-	Description:	+	Description: Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form

OCA at 05:03, 18 May 2011

OCA — Wed, 18 May 2011 05:03:15 GMT

←Older revision		Revision as of 05:03, 18 May 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2yhq is ON HOLD ~~until sometime in the future~~	+	The entry 2yhq is ON HOLD

	Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.		Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.

	Description:		Description:

OCA: Protected "2yhq" [edit=sysop:move=sysop]

OCA — Thu, 12 May 2011 04:11:40 GMT

Protected "2yhq" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:11, 12 May 2011

OCA: New page: '''Unreleased structure''' The entry 2yhq is ON HOLD until sometime in the future Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R...

OCA — Thu, 12 May 2011 04:11:39 GMT

New page: '''Unreleased structure''' The entry 2yhq is ON HOLD until sometime in the future Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R...

New page

'''Unreleased structure'''

The entry 2yhq is ON HOLD until sometime in the future

Authors: El Omari, K., Dhaliwal, B., Ren, J., Abrescia, N.G.A., Lockyer, M., Powell, K.L., Hawkins, A.R., Stammers, D.K.

Description: