2yii - Revision history

OCA at 08:14, 23 August 2023

OCA — Wed, 23 Aug 2023 08:14:23 GMT

←Older revision		Revision as of 08:14, 23 August 2023
Line 3:		Line 3:
	<StructureSection load='2yii' size='340' side='right'caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>		<StructureSection load='2yii' size='340' side='right'caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Chinese_yew Chinese yew~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YII FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Taxus_chinensis Taxus chinensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YII FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.18Å</td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [https://pdbe.org/2yii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [https://www.ebi.ac.uk/pdbsum/2yii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yii ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [https://pdbe.org/2yii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [https://www.ebi.ac.uk/pdbsum/2yii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yii ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PAM_TAXWC PAM_TAXWC] Phenylalanine aminomutase that catalyzes the rearrangement of L-phenylalanine to R-beta-phenylalanine. Catalyzes the first commited step in the biosynthesis of the side chain of the alkaloid taxol (paclitaxel), a widely-used compound with antitumor activity. Has also low phenylalanine ammonia-lyase activity and can catalyze the amination of trans-cinnamate.<ref>PMID:15878763</ref> <ref>PMID:22113970</ref> <ref>PMID:24786474</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chinese yew]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bartsch, S]]	+	[[Category: Taxus chinensis]]
-	[[Category: Dijkstra~~, B W~~]]	+	[[Category: Bartsch S]]
-	[[Category: Feringa~~, B L~~]]	+	[[Category: Dijkstra BW]]
-	[[Category: Heberling~~, M M~~]]	+	[[Category: Feringa BL]]
-	[[Category: Janssen~~, D B~~]]	+	[[Category: Heberling MM]]
-	[[Category: Poelarends~~, G J~~]]	+	[[Category: Janssen DB]]
-	[[Category: Szymanski, W]]	+	[[Category: Poelarends GJ]]
-	[[Category: Wildeman, S]]	+	[[Category: Szymanski W]]
-	[[Category: Wu, B]]	+	[[Category: Wildeman S]]
-	[[Category: Wybenga~~, G G]]~~	+	[[Category: Wu B]]
-	~~[[Category: Lyase~~]]	+	[[Category: Wybenga GG]]

OCA at 15:05, 17 November 2021

OCA — Wed, 17 Nov 2021 15:05:49 GMT

←Older revision		Revision as of 15:05, 17 November 2021
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	<StructureSection load='2yii' size='340' side='right'caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>		<StructureSection load='2yii' size='340' side='right'caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Chinese_yew Chinese yew]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2YII FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chinese_yew Chinese yew]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YII FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [~~http~~://pdbe.org/2yii PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2yii PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2yii ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [https://pdbe.org/2yii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [https://www.ebi.ac.uk/pdbsum/2yii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yii ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:17, 23 October 2019

OCA — Wed, 23 Oct 2019 07:17:42 GMT

←Older revision		Revision as of 07:17, 23 October 2019
Line 1:		Line 1:

	==Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution==		==Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution==
-	<StructureSection load='2yii' size='340' side='right' caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>	+	<StructureSection load='2yii' size='340' side='right'caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_yew Chinese yew]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YII FirstGlance]. <br>		<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_yew Chinese yew]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YII FirstGlance]. <br>
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[Aminomutase\|Aminomutase]]	+	*[[Aminomutase 3D structures\|Aminomutase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Chinese yew]]		[[Category: Chinese yew]]
		+	[[Category: Large Structures]]
	[[Category: Bartsch, S]]		[[Category: Bartsch, S]]
	[[Category: Dijkstra, B W]]		[[Category: Dijkstra, B W]]

OCA at 14:38, 11 August 2016

OCA — Thu, 11 Aug 2016 14:38:57 GMT

←Older revision		Revision as of 14:38, 11 August 2016
Line 1:		Line 1:
		+
	==Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution==		==Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution==
	<StructureSection load='2yii' size='340' side='right' caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>		<StructureSection load='2yii' size='340' side='right' caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Taxus_wallichiana_var._chinensis Taxus wallichiana var. chinensis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YII FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_yew Chinese yew]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YII FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [http://www.ebi.ac.uk/pdbsum/2yii PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [http://pdbe.org/2yii PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [http://www.ebi.ac.uk/pdbsum/2yii PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yii ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2yii" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Aminomutase\|Aminomutase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Taxus wallichiana var. chinensis~~]]	+	[[Category: Chinese yew]]
	[[Category: Bartsch, S]]		[[Category: Bartsch, S]]
	[[Category: Dijkstra, B W]]		[[Category: Dijkstra, B W]]

OCA at 07:56, 12 November 2014

OCA — Wed, 12 Nov 2014 07:56:24 GMT

←Older revision		Revision as of 07:56, 12 November 2014
Line 1:		Line 1:
-	[[~~Image:~~2yii.~~png~~\|~~left~~\|~~200px~~]]	+	==Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution==
		+	<StructureSection load='2yii' size='340' side='right' caption='[[2yii]], [[Resolution\|resolution]] 2.18Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2yii]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Taxus_wallichiana_var._chinensis Taxus wallichiana var. chinensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YII FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yii OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yii RCSB], [http://www.ebi.ac.uk/pdbsum/2yii PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Turn to switch: A mutant of phenylalanine aminomutase was engineered that can catalyze the regioselective amination of cinnamate derivatives (see scheme, red) to, for example, beta-amino acids. This regioselectivity, along with the X-ray crystal structures, suggests two distinct carboxylate binding modes differentiated by C(beta)-C(ipso) bond rotation, which determines if beta- (see scheme) or alpha-addition takes place.

-	~~{{STRUCTURE_2yii\| PDB=2yii \| SCENE= }}~~	+	Mechanism-inspired engineering of phenylalanine aminomutase for enhanced beta-regioselective asymmetric amination of cinnamates.,Wu B, Szymanski W, Wybenga GG, Heberling MM, Bartsch S, de Wildeman S, Poelarends GJ, Feringa BL, Dijkstra BW, Janssen DB Angew Chem Int Ed Engl. 2012 Jan 9;51(2):482-6. doi: 10.1002/anie.201106372. Epub, 2011 Nov 23. PMID:22113970<ref>PMID:22113970</ref>

-	~~===Manipulating the regioselectivity~~ of ~~phenylalanine aminomutase: new insights into~~ the ~~reaction mechanism~~ of ~~MIO-dependent enzymes from structure-guided directed evolution===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22113970}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[2yii]] is a 4 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Taxus_wallichiana_var._chinensis Taxus wallichiana var. chinensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA].~~	+	</StructureSection>
	[[Category: Taxus wallichiana var. chinensis]]		[[Category: Taxus wallichiana var. chinensis]]
-	[[Category: Bartsch, S.]]	+	[[Category: Bartsch, S]]
-	[[Category: Dijkstra, B W.]]	+	[[Category: Dijkstra, B W]]
-	[[Category: Feringa, B L.]]	+	[[Category: Feringa, B L]]
-	[[Category: Heberling, M M.]]	+	[[Category: Heberling, M M]]
-	[[Category: Janssen, D B.]]	+	[[Category: Janssen, D B]]
-	[[Category: Poelarends, G J.]]	+	[[Category: Poelarends, G J]]
-	[[Category: Szymanski, W.]]	+	[[Category: Szymanski, W]]
-	[[Category: Wildeman, S.]]	+	[[Category: Wildeman, S]]
-	[[Category: Wu, B.]]	+	[[Category: Wu, B]]
-	[[Category: Wybenga, G G.]]	+	[[Category: Wybenga, G G]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 12:24, 30 January 2013

OCA — Wed, 30 Jan 2013 12:24:44 GMT

←Older revision		Revision as of 12:24, 30 January 2013
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	[[Image:2yii.png\|left\|200px]]		[[Image:2yii.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2yii", creates the "Structure Box" on the page.
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	{{STRUCTURE_2yii\| PDB=2yii \| SCENE= }}		{{STRUCTURE_2yii\| PDB=2yii \| SCENE= }}

	===Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution===		===Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution===

		+	{{ABSTRACT_PUBMED_22113970}}

	==About this Structure==		==About this Structure==

OCA at 05:42, 25 January 2012

OCA — Wed, 25 Jan 2012 05:42:26 GMT

←Older revision		Revision as of 05:42, 25 January 2012
Line 1:		Line 1:
-	[[Image:2yii.~~jpg~~\|left\|200px]]	+	[[Image:2yii.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2yii\| PDB=2yii \| SCENE= }}		{{STRUCTURE_2yii\| PDB=2yii \| SCENE= }}

-	===~~MANIPULATING THE REGIOSELECTIVITY OF PHENYLALANINE AMINOMUTASE~~: ~~NEW INSIGHTS INTO THE REACTION MECHANISM OF~~ MIO-~~DEPENDENT ENZYMES FROM STRUCTURE~~-~~GUIDED DIRECTED EVOLUTION~~===	+	===Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution===

OCA at 11:44, 9 November 2011

OCA — Wed, 09 Nov 2011 11:44:45 GMT

←Older revision		Revision as of 11:44, 9 November 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2yii.jpg\|left\|200px]]

-	The ~~entry 2yii~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2yii", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2yii\| PDB=2yii \| SCENE= }}

-	~~Authors~~: ~~Wu, B., Szymanski, W., Wybenga, G.G., Heberling, M.M., Bartsch, S., Wildeman, S., Poelarends, G.J., Feringa, B.L., Dijkstra, B.W., Janssen, D.B.~~	+	===MANIPULATING THE REGIOSELECTIVITY OF PHENYLALANINE AMINOMUTASE: NEW INSIGHTS INTO THE REACTION MECHANISM OF MIO-DEPENDENT ENZYMES FROM STRUCTURE-GUIDED DIRECTED EVOLUTION===

-	~~Description~~: ~~Manipulating the regioselectivity of phenylalanine aminomutase~~: ~~new insights into the reaction mechanism of MIO~~-~~dependent enzymes from structure-guided directed evolution~~	+
		+	==About this Structure==
		+	[[2yii]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Taxus_wallichiana_var._chinensis Taxus wallichiana var. chinensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YII OCA].
		+	[[Category: Taxus wallichiana var. chinensis]]
		+	[[Category: Bartsch, S.]]
		+	[[Category: Dijkstra, B W.]]
		+	[[Category: Feringa, B L.]]
		+	[[Category: Heberling, M M.]]
		+	[[Category: Janssen, D B.]]
		+	[[Category: Poelarends, G J.]]
		+	[[Category: Szymanski, W.]]
		+	[[Category: Wildeman, S.]]
		+	[[Category: Wu, B.]]
		+	[[Category: Wybenga, G G.]]
		+	[[Category: Lyase]]

OCA at 05:10, 1 June 2011

OCA — Wed, 01 Jun 2011 05:10:52 GMT

←Older revision		Revision as of 05:10, 1 June 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2yii is ON HOLD	+	The entry 2yii is ON HOLD until Paper Publication

	Authors: Wu, B., Szymanski, W., Wybenga, G.G., Heberling, M.M., Bartsch, S., Wildeman, S., Poelarends, G.J., Feringa, B.L., Dijkstra, B.W., Janssen, D.B.		Authors: Wu, B., Szymanski, W., Wybenga, G.G., Heberling, M.M., Bartsch, S., Wildeman, S., Poelarends, G.J., Feringa, B.L., Dijkstra, B.W., Janssen, D.B.

	Description: Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution		Description: Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution

OCA: Protected "2yii" [edit=sysop:move=sysop]

OCA — Wed, 25 May 2011 04:55:17 GMT

Protected "2yii" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:55, 25 May 2011