2yqc - Revision history

OCA at 09:04, 25 October 2023

OCA — Wed, 25 Oct 2023 09:04:41 GMT

←Older revision		Revision as of 09:04, 25 October 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [https://pdbe.org/2yqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [https://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [https://pdbe.org/2yqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [https://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>
	</table>		</table>

OCA at 04:29, 30 September 2022

OCA — Fri, 30 Sep 2022 04:29:32 GMT

←Older revision		Revision as of 04:29, 30 September 2022
Line 3:		Line 3:
	<StructureSection load='2yqc' size='340' side='right'caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2yqc' size='340' side='right'caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_11006_[[monilia_stellatoidea]] Atcc 11006 [[monilia stellatoidea]]~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [https://pdbe.org/2yqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [https://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [https://pdbe.org/2yqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [https://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/UAP1_CANAX UAP1_CANAX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Candida albicans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: UDP-N-acetylglucosamine diphosphorylase]]~~	+	[[Category: Kita A]]
-	[[Category: Kita, A]]	+	[[Category: Maruyama D]]
-	[[Category: Maruyama, D]]	+	[[Category: Miki K]]
-	[[Category: Miki, K]]	+	[[Category: Nishitani Y]]
-	[[Category: Nishitani, Y]]	+	[[Category: Nonaka T]]
-	[[Category: Nonaka, T]]	+
-	~~[[Category: Candida albican]]~~	+
-	~~[[Category: N-acetylglucosamine]]~~	+
-	~~[[Category: N-acetylglucosamine-1-phosphate]]~~	+
-	~~[[Category: Pyrophosphorylase]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Uridine-diphospho-n-acetylglucosamine~~]]	+

OCA at 07:10, 10 November 2021

OCA — Wed, 10 Nov 2021 07:10:03 GMT

←Older revision		Revision as of 07:10, 10 November 2021
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	<StructureSection load='2yqc' size='340' side='right'caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2yqc' size='340' side='right'caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_11006_[[~~candida_stellatoidea~~]] Atcc 11006 [[~~candida~~ stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_11006_[[monilia_stellatoidea]] Atcc 11006 [[monilia stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [~~http~~://pdbe.org/2yqc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [https://pdbe.org/2yqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [https://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 13:02, 22 July 2020

OCA — Wed, 22 Jul 2020 13:02:38 GMT

←Older revision		Revision as of 13:02, 22 July 2020
Line 1:		Line 1:

	==Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form==		==Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form==
-	<StructureSection load='2yqc' size='340' side='right' caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2yqc' size='340' side='right'caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2YQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://pdbe.org/2yqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://pdbe.org/2yqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: UDP-N-acetylglucosamine diphosphorylase]]		[[Category: UDP-N-acetylglucosamine diphosphorylase]]
	[[Category: Kita, A]]		[[Category: Kita, A]]

OCA at 09:30, 17 October 2018

OCA — Wed, 17 Oct 2018 09:30:31 GMT

←Older revision		Revision as of 09:30, 17 October 2018
Line 1:		Line 1:
		+
	==Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form==		==Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form==
	<StructureSection load='2yqc' size='340' side='right' caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2yqc' size='340' side='right' caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://pdbe.org/2yqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://pdbe.org/2yqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqc ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yq/2yqc_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yq/2yqc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:08, 9 February 2016

OCA — Tue, 09 Feb 2016 05:08:56 GMT

←Older revision		Revision as of 05:08, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2yqc' size='340' side='right' caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2yqc' size='340' side='right' caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Candida_albicans Candida albicans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://pdbe.org/2yqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yqc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2yqc" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Candida albicans]]
	[[Category: UDP-N-acetylglucosamine diphosphorylase]]		[[Category: UDP-N-acetylglucosamine diphosphorylase]]
	[[Category: Kita, A]]		[[Category: Kita, A]]

OCA at 11:46, 20 January 2015

OCA — Tue, 20 Jan 2015 11:46:41 GMT

←Older revision		Revision as of 11:46, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	[[Category: Candida albicans]]		[[Category: Candida albicans]]
	[[Category: UDP-N-acetylglucosamine diphosphorylase]]		[[Category: UDP-N-acetylglucosamine diphosphorylase]]
-	[[Category: Kita, A.]]	+	[[Category: Kita, A]]
-	[[Category: Maruyama, D.]]	+	[[Category: Maruyama, D]]
-	[[Category: Miki, K.]]	+	[[Category: Miki, K]]
-	[[Category: Nishitani, Y.]]	+	[[Category: Nishitani, Y]]
-	[[Category: Nonaka, T.]]	+	[[Category: Nonaka, T]]
	[[Category: Candida albican]]		[[Category: Candida albican]]
	[[Category: N-acetylglucosamine]]		[[Category: N-acetylglucosamine]]

OCA at 05:37, 2 October 2014

OCA — Thu, 02 Oct 2014 05:37:49 GMT

←Older revision		Revision as of 05:37, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2yqc.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form==
		+	<StructureSection load='2yqc' size='340' side='right' caption='[[2yqc]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQC FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2yqh\|2yqh]], [[2yqj\|2yqj]], [[2yqs\|2yqs]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yqc RCSB], [http://www.ebi.ac.uk/pdbsum/2yqc PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yq/2yqc_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Uridine-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a precursor of the bacterial and fungal cell wall. It is also used in a component of N-linked glycosylation and the glycosylphosphoinositol anchor of eukaryotic proteins. It is synthesized from N-acetylglucosamine-1-phosphate (GlcNAc-1-P) and uridine-5'-triphosphate (UTP) by UDP-GlcNAc pyrophosphorylase (UAP). This is an S(N)2 reaction; the non-esterified oxygen atom of the GlcNAc-1-P phosphate group attacks the alpha-phosphate group of UTP. We determined crystal structures of UAP from Candida albicans (CaUAP1) without any ligands and also complexed with its substrate or with its product. The series of structures in different forms shows the induced fit movements of CaUAP1. Three loops approaching the ligand molecule close the active site when ligand is bound. In addition, Lys-421, instead of the metal ion in prokaryotic UAPs, is coordinated by both phosphate groups of UDP-Glc-NAc and acts as a cofactor. However, a magnesium ion enhances the enzymatic activity of CaUAP1, and thus we propose that the magnesium ion increases the affinity between UTP and the enzyme by coordinating to the alpha- and gamma-phosphate group of UTP.

-	~~{{STRUCTURE_2yqc\| PDB=2yqc \| SCENE= }}~~	+	Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans and catalytic reaction mechanism.,Maruyama D, Nishitani Y, Nonaka T, Kita A, Fukami TA, Mio T, Yamada-Okabe H, Yamada-Okabe T, Miki K J Biol Chem. 2007 Jun 8;282(23):17221-30. Epub 2007 Mar 28. PMID:17392279<ref>PMID:17392279</ref>

-	~~===Crystal Structure~~ of ~~uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in~~ the ~~apo-like form===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17392279}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2yqc]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Candida_albicans Candida albicans]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017392279<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Candida albicans]]		[[Category: Candida albicans]]
	[[Category: UDP-N-acetylglucosamine diphosphorylase]]		[[Category: UDP-N-acetylglucosamine diphosphorylase]]

OCA: Protected "2yqc" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 20:26:40 GMT

Protected "2yqc" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:26, 7 January 2013

OCA at 20:26, 7 January 2013

OCA — Mon, 07 Jan 2013 20:26:37 GMT

←Older revision		Revision as of 20:26, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2yqc.png\|left\|200px]]		[[Image:2yqc.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2yqc", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2yqc\| PDB=2yqc \| SCENE= }}		{{STRUCTURE_2yqc\| PDB=2yqc \| SCENE= }}

	===Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form===		===Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17392279}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17392279 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17392279}}		{{ABSTRACT_PUBMED_17392279}}

	==About this Structure==		==About this Structure==
-	~~2YQC~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA].	+	[[2yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQC OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17392279~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017392279</ref><references group="xtra"/>
	[[Category: Candida albicans]]		[[Category: Candida albicans]]
	[[Category: UDP-N-acetylglucosamine diphosphorylase]]		[[Category: UDP-N-acetylglucosamine diphosphorylase]]
Line 32:		Line 20:
	[[Category: Nonaka, T.]]		[[Category: Nonaka, T.]]
	[[Category: Candida albican]]		[[Category: Candida albican]]
-	[[Category: Crystal structure]]
	[[Category: N-acetylglucosamine]]		[[Category: N-acetylglucosamine]]
	[[Category: N-acetylglucosamine-1-phosphate]]		[[Category: N-acetylglucosamine-1-phosphate]]
	[[Category: Pyrophosphorylase]]		[[Category: Pyrophosphorylase]]
		+	[[Category: Transferase]]
	[[Category: Uridine-diphospho-n-acetylglucosamine]]		[[Category: Uridine-diphospho-n-acetylglucosamine]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:43:27 2009''