2yxq - Revision history

OCA at 09:10, 25 October 2023

OCA — Wed, 25 Oct 2023 09:10:08 GMT

←Older revision		Revision as of 09:10, 25 October 2023
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	<StructureSection load='2yxq' size='340' side='right'caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2yxq' size='340' side='right'caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43067 Atcc 43067~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1rhz\|1rhz]], [[1rh5\|1rh5]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.5Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">secY ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&id=2190 ATCC 43067]), secE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [https://pdbe.org/2yxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [https://www.ebi.ac.uk/pdbsum/2yxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [https://pdbe.org/2yxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [https://www.ebi.ac.uk/pdbsum/2yxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA]] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. [[https://www.uniprot.org/uniprot/SECG_METJA SECG_METJA]] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [[https://www.uniprot.org/uniprot/SECE_METJA SECE_METJA]] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.	+	[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
-	*[[Preprotein translocase\|Preprotein translocase]]	+	*[[Preprotein translocase 3D structures\|Preprotein translocase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 43067]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Li, W~~]]	+	[[Category: Methanocaldococcus jannaschii]]
-	[[Category: ~~Schulman, S~~]]	+	[[Category: Li W]]
-	[[Category: ~~Membrane protein]]~~	+	[[Category: Schulman S]]
-	~~[[Category: Prl mutation]]~~	+
-	~~[[Category: Protein secretion]]~~	+
-	~~[[Category: Protein translocation]]~~	+
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Signal peptide~~]]	+

OCA at 10:42, 8 December 2021

OCA — Wed, 08 Dec 2021 10:42:30 GMT

←Older revision		Revision as of 10:42, 8 December 2021
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	==The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal==		==The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal==
-	<StructureSection load='2yxq' size='340' side='right' caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>	+	<StructureSection load='2yxq' size='340' side='right'caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rhz\|1rhz]], [[1rh5\|1rh5]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secE ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secG ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secG ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [~~http~~://pdbe.org/2yxq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2yxq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [https://pdbe.org/2yxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [https://www.ebi.ac.uk/pdbsum/2yxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SECY_METJA SECY_METJA]] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. [[~~http~~://www.uniprot.org/uniprot/SECG_METJA SECG_METJA]] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [[~~http~~://www.uniprot.org/uniprot/SECE_METJA SECE_METJA]] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.	+	[[https://www.uniprot.org/uniprot/SECY_METJA SECY_METJA]] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. [[https://www.uniprot.org/uniprot/SECG_METJA SECG_METJA]] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [[https://www.uniprot.org/uniprot/SECE_METJA SECE_METJA]] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 43067]]		[[Category: Atcc 43067]]
		+	[[Category: Large Structures]]
	[[Category: Li, W]]		[[Category: Li, W]]
	[[Category: Schulman, S]]		[[Category: Schulman, S]]

OCA at 09:34, 17 October 2018

OCA — Wed, 17 Oct 2018 09:34:18 GMT

←Older revision		Revision as of 09:34, 17 October 2018
Line 1:		Line 1:
		+
	==The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal==		==The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal==
	<StructureSection load='2yxq' size='340' side='right' caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2yxq' size='340' side='right' caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://pdbe.org/2yxq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://pdbe.org/2yxq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yxq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:58, 7 February 2016

OCA — Sun, 07 Feb 2016 13:58:06 GMT

←Older revision		Revision as of 13:58, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2yxq' size='340' side='right' caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>		<StructureSection load='2yxq' size='340' side='right' caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanocaldococcus_jannaschii Methanocaldococcus jannaschii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ~~Methanocaldococcus jannaschii~~]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ~~Methanocaldococcus jannaschii~~]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ~~Methanocaldococcus jannaschii~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://pdbe.org/2yxq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yxq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Methanocaldococcus jannaschii~~]]	+	[[Category: Atcc 43067]]
	[[Category: Li, W]]		[[Category: Li, W]]
	[[Category: Schulman, S]]		[[Category: Schulman, S]]

OCA at 15:41, 24 December 2014

OCA — Wed, 24 Dec 2014 15:41:26 GMT

←Older revision		Revision as of 15:41, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SECY_METJA SECY_METJA]] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. [[http://www.uniprot.org/uniprot/SECG_METJA SECG_METJA]] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [[http://www.uniprot.org/uniprot/SECE_METJA SECE_METJA]] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
-	[[Category: Li, W.]]	+	[[Category: Li, W]]
-	[[Category: Schulman, S.]]	+	[[Category: Schulman, S]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]
	[[Category: Prl mutation]]		[[Category: Prl mutation]]

OCA at 05:40, 2 October 2014

OCA — Thu, 02 Oct 2014 05:40:14 GMT

←Older revision		Revision as of 05:40, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2yxq.~~png~~\|~~left~~\|200px]]	+	==The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal==
		+	<StructureSection load='2yxq' size='340' side='right' caption='[[2yxq]], [[Resolution\|resolution]] 3.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2yxq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YXQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rhz\|1rhz]], [[1rh5\|1rh5]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">secY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]), secE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii]), secG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yxq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yxq RCSB], [http://www.ebi.ac.uk/pdbsum/2yxq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yx/2yxq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

-	~~{{STRUCTURE_2yxq\| PDB~~=~~2yxq \| SCENE= }}~~	+	==See Also==
-		+	*[[Preprotein translocase\|Preprotein translocase]]
-	~~===The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal~~===	+	__TOC__
-		+	</StructureSection>
-		+
-	~~==About this Structure==~~	+
-	[[~~2yxq~~]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA].	+
-		+
-	~~==Reference==~~	+
-	<~~ref group="xtra">PMID:017531803</ref><references group="xtra"~~/>	+
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
	[[Category: Li, W.]]		[[Category: Li, W.]]

OCA: Protected "2yxq" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:47:32 GMT

Protected "2yxq" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:47, 7 January 2013

OCA at 21:47, 7 January 2013

OCA — Mon, 07 Jan 2013 21:47:26 GMT

←Older revision		Revision as of 21:47, 7 January 2013
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-	{{Seed}}
	[[Image:2yxq.png\|left\|200px]]		[[Image:2yxq.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2yxq\| PDB=2yxq \| SCENE= }}		{{STRUCTURE_2yxq\| PDB=2yxq \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2YXQ~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA].	+	[[2yxq]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17531803~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017531803</ref><references group="xtra"/>
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
	[[Category: Li, W.]]		[[Category: Li, W.]]
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	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Signal peptide]]		[[Category: Signal peptide]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:16:25 2009''

OCA at 12:16, 16 February 2009

OCA — Mon, 16 Feb 2009 12:16:27 GMT

←Older revision		Revision as of 12:16, 16 February 2009
Line 14:		Line 14:

	==About this Structure==		==About this Structure==
-	2YXQ is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA].	+	2YXQ is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YXQ OCA].

	==Reference==		==Reference==
-	~~Puzzle plugged by protein pore plasticity., Minor DL Jr, Mol Cell. 2007 May 25;26(4):459-60.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17531803 17531803]~~	+	<ref group="xtra">PMID:17531803</ref><references group="xtra"/>
	[[Category: Methanocaldococcus jannaschii]]		[[Category: Methanocaldococcus jannaschii]]
-	[[Category: Protein complex]]
	[[Category: Li, W.]]		[[Category: Li, W.]]
	[[Category: Schulman, S.]]		[[Category: Schulman, S.]]
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	[[Category: Signal peptide]]		[[Category: Signal peptide]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27~~ 16:52:~~56 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:16:25 2009''

OCA at 13:52, 27 July 2008

OCA — Sun, 27 Jul 2008 13:52:59 GMT

←Older revision		Revision as of 13:52, 27 July 2008
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-	[[Image:2yxq.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2yxq.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2yxq\| PDB=2yxq \| SCENE= }}		{{STRUCTURE_2yxq\| PDB=2yxq \| SCENE= }}

-	~~'''~~The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal~~'''~~	+	===The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal===


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	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Signal peptide]]		[[Category: Signal peptide]]
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