2z36 - Revision history

OCA at 13:20, 1 November 2023

OCA — Wed, 01 Nov 2023 13:20:25 GMT

←Older revision		Revision as of 13:20, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2z36' size='340' side='right'caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2z36' size='340' side='right'caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Actinomadura_recticatena Actinomadura~~ recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Actinomadura recticatena])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [https://pdbe.org/2z36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [https://www.ebi.ac.uk/pdbsum/2z36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z36 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [https://pdbe.org/2z36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [https://www.ebi.ac.uk/pdbsum/2z36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z36 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q2L6S8_9ACTN Q2L6S8_9ACTN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Actinomadura recticatena]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arisawa, A]]	+	[[Category: Nonomuraea recticatena]]
-	[[Category: Fujii, T]]	+	[[Category: Arisawa A]]
-	[[Category: Fujii, Y]]	+	[[Category: Fujii T]]
-	[[Category: Tamura, T]]	+	[[Category: Fujii Y]]
-	[[Category: Yasutake, Y]]	+	[[Category: Tamura T]]
-	~~[[Category: Cyp105]]~~	+	[[Category: Yasutake Y]]
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: P450~~]]	+

OCA at 10:44, 8 December 2021

OCA — Wed, 08 Dec 2021 10:44:33 GMT

←Older revision		Revision as of 10:44, 8 December 2021
Line 1:		Line 1:

	==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==		==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==
-	<StructureSection load='2z36' size='340' side='right' caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='2z36' size='340' side='right'caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Actinomadura_recticatena Actinomadura recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_recticatena Actinomadura recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Actinomadura recticatena])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Actinomadura recticatena])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [~~http~~://pdbe.org/2z36 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2z36 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2z36 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [https://pdbe.org/2z36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [https://www.ebi.ac.uk/pdbsum/2z36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z36 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Actinomadura recticatena]]		[[Category: Actinomadura recticatena]]
		+	[[Category: Large Structures]]
	[[Category: Arisawa, A]]		[[Category: Arisawa, A]]
	[[Category: Fujii, T]]		[[Category: Fujii, T]]

OCA at 09:38, 17 October 2018

OCA — Wed, 17 Oct 2018 09:38:22 GMT

←Older revision		Revision as of 09:38, 17 October 2018
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z36_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z36_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:37, 11 August 2016

OCA — Thu, 11 Aug 2016 17:37:41 GMT

←Older revision		Revision as of 17:37, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==		==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==
	<StructureSection load='2z36' size='340' side='right' caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2z36' size='340' side='right' caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Nonomuraea_recticatena Nonomuraea~~ recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomadura_recticatena Actinomadura recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 ~~Nonomuraea~~ recticatena])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Actinomadura recticatena])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [http://www.ebi.ac.uk/pdbsum/2z36 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [http://pdbe.org/2z36 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [http://www.ebi.ac.uk/pdbsum/2z36 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z36 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z36 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2z36" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Nonomuraea~~ recticatena]]	+	[[Category: Actinomadura recticatena]]
	[[Category: Arisawa, A]]		[[Category: Arisawa, A]]
	[[Category: Fujii, T]]		[[Category: Fujii, T]]

OCA at 11:54, 20 January 2015

OCA — Tue, 20 Jan 2015 11:54:50 GMT

←Older revision		Revision as of 11:54, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Nonomuraea recticatena])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Nonomuraea recticatena])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [http://www.ebi.ac.uk/pdbsum/2z36 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [http://www.ebi.ac.uk/pdbsum/2z36 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Nonomuraea recticatena]]		[[Category: Nonomuraea recticatena]]
-	[[Category: Arisawa, A.]]	+	[[Category: Arisawa, A]]
-	[[Category: Fujii, T.]]	+	[[Category: Fujii, T]]
-	[[Category: Fujii, Y.]]	+	[[Category: Fujii, Y]]
-	[[Category: Tamura, T.]]	+	[[Category: Tamura, T]]
-	[[Category: Yasutake, Y.]]	+	[[Category: Yasutake, Y]]
	[[Category: Cyp105]]		[[Category: Cyp105]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: P450]]		[[Category: P450]]

OCA at 05:41, 2 October 2014

OCA — Thu, 02 Oct 2014 05:41:56 GMT

←Older revision		Revision as of 05:41, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2z36.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)==
		+	<StructureSection load='2z36' size='340' side='right' caption='[[2z36]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z36 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">moxA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46178 Nonomuraea recticatena])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z36 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z36 RCSB], [http://www.ebi.ac.uk/pdbsum/2z36 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/2z36_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cytochrome P450 MoxA (P450moxA) from a rare actinomycete Nonomuraea recticatena belongs to the CYP105 family and exhibits remarkably broad substrate specificity. Here, we demonstrate that P450moxA acts on several luciferin derivatives, which were originally identified as substrates of the human microsomal P450s. We also describe the crystal structure of P450moxA in substrate-free form. Structural comparison with various bacterial and human microsomal P450s reveals that the P450moxA structure is most closely related to that of the fungal nitric oxide reductase P450nor (CYP55A1). Final refined model of P450moxA comprises almost all the residues, including the "BC-loop" and "FG-loop" regions pivotal for substrate recognition, and the current structure thus defines a well-ordered substrate-binding pocket. Clear electron density map reveals that the MES molecule is bound to the substrate-binding site, and the sixth coordination position of the heme iron is not occupied by a water molecule, probably due to the presence of MES molecule in the vicinity of the heme. The unexpected binding of the MES molecule might reflect the ability of P450moxA to accommodate a broad range of structurally diverse compounds.

-	~~{{STRUCTURE_2z36\| PDB=2z36 \| SCENE= }}~~	+	Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105).,Yasutake Y, Imoto N, Fujii Y, Fujii T, Arisawa A, Tamura T Biochem Biophys Res Commun. 2007 Oct 5;361(4):876-82. Epub 2007 Jul 25. PMID:17679139<ref>PMID:17679139</ref>

-	~~===Crystal structure~~ of ~~cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17679139}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2z36]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017679139<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Nonomuraea recticatena]]		[[Category: Nonomuraea recticatena]]
	[[Category: Arisawa, A.]]		[[Category: Arisawa, A.]]

OCA: Protected "2z36" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 20:33:32 GMT

Protected "2z36" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:33, 7 January 2013

OCA at 20:33, 7 January 2013

OCA — Mon, 07 Jan 2013 20:33:30 GMT

←Older revision		Revision as of 20:33, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2z36.png\|left\|200px]]		[[Image:2z36.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2z36", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2z36\| PDB=2z36 \| SCENE= }}		{{STRUCTURE_2z36\| PDB=2z36 \| SCENE= }}

	===Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)===		===Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17679139}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17679139 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17679139}}		{{ABSTRACT_PUBMED_17679139}}

	==About this Structure==		==About this Structure==
-	~~2Z36~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA].	+	[[2z36]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17679139~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017679139</ref><references group="xtra"/>
	[[Category: Nonomuraea recticatena]]		[[Category: Nonomuraea recticatena]]
	[[Category: Arisawa, A.]]		[[Category: Arisawa, A.]]
Line 33:		Line 21:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: P450]]		[[Category: P450]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:52:51 2009''

OCA at 04:52, 18 February 2009

OCA — Wed, 18 Feb 2009 04:52:52 GMT

←Older revision		Revision as of 04:52, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2Z36 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA].	+	2Z36 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Nonomuraea_recticatena Nonomuraea recticatena]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z36 OCA].

	==Reference==		==Reference==
-	Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)., Yasutake Y, Imoto N, Fujii Y, Fujii T, Arisawa A, Tamura T, Biochem Biophys Res Commun. 2007 Oct 5;361(4):876-82. Epub 2007 Jul 25. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17679139 17679139]~~	+	<ref group="xtra">PMID:17679139</ref><references group="xtra"/>
	[[Category: Nonomuraea recticatena]]		[[Category: Nonomuraea recticatena]]
-	[[Category: Single protein]]
	[[Category: Arisawa, A.]]		[[Category: Arisawa, A.]]
	[[Category: Fujii, T.]]		[[Category: Fujii, T.]]
Line 35:		Line 34:
	[[Category: P450]]		[[Category: P450]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 13~~:39:~~16 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:52:51 2009''

OCA at 10:39, 29 July 2008

OCA — Tue, 29 Jul 2008 10:39:17 GMT

←Older revision		Revision as of 10:39, 29 July 2008
Line 1:		Line 1:
-	[[Image:2z36.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2z36.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2z36\| PDB=2z36 \| SCENE= }}		{{STRUCTURE_2z36\| PDB=2z36 \| SCENE= }}

-	~~'''~~Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)~~'''~~	+	===Crystal structure of cytochrome P450 MoxA from Nonomuraea recticatena (CYP105)===


-	~~==Overview==~~	+	<!--
-	~~Cytochrome P450 MoxA (P450moxA) from a rare actinomycete Nonomuraea recticatena belongs to the CYP105 family and exhibits remarkably broad substrate specificity. Here~~, ~~we demonstrate that P450moxA acts on several luciferin derivatives~~, ~~which were originally identified as substrates of~~ the human microsomal P450s. We also describe the crystal structure of P450moxA in substrate-free form. Structural comparison with various bacterial and human microsomal P450s reveals that the P450moxA structure is most closely related to ~~that of~~ the ~~fungal nitric oxide reductase P450nor~~ (~~CYP55A1)~~. Final refined model of P450moxA comprises almost all the residues, including the "BC-loop" and "FG-loop" regions pivotal for substrate recognition, and the current structure thus defines a well-ordered substrate-binding pocket. ~~Clear electron density map reveals that the MES molecule is bound to the substrate-binding site~~, ~~and the sixth coordination position of the heme iron~~ is ~~not occupied by a water molecule, probably due to~~ the ~~presence of MES molecule in the vicinity of the heme. The unexpected binding of the MES molecule might reflect the ability of P450moxA to accommodate a broad range of structurally diverse compounds~~.	+	The line below this paragraph, {{ABSTRACT_PUBMED_17679139}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 17679139 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_17679139}}

	==About this Structure==		==About this Structure==
Line 30:		Line 34:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: P450]]		[[Category: P450]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 19~~:53:47 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:39:16 2008''