2z76 - Revision history

OCA at 11:59, 30 August 2023

OCA — Wed, 30 Aug 2023 11:59:58 GMT

←Older revision		Revision as of 11:59, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2z76' size='340' side='right'caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>		<StructureSection load='2z76' size='340' side='right'caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Myctu Myctu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.82Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [https://pdbe.org/2z76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [https://www.ebi.ac.uk/pdbsum/2z76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z76 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [https://pdbe.org/2z76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [https://www.ebi.ac.uk/pdbsum/2z76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z76 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/P71817_MYCTO P71817_MYCTO]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Myctu~~]]	+	[[Category: Mycobacterium tuberculosis H37Rv]]
-	[[Category: Cherney~~, M M~~]]	+	[[Category: Cherney MM]]
-	[[Category: Garen~~, C R~~]]	+	[[Category: Garen CR]]
-	[[Category: James~~, M N.G]]~~	+	[[Category: James MNG]]
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Alpha+beta conical barrel]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Tbsgc~~]]	+

OCA at 10:47, 8 December 2021

OCA — Wed, 08 Dec 2021 10:47:25 GMT

←Older revision		Revision as of 10:47, 8 December 2021
Line 1:		Line 1:

	==X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution==		==X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution==
-	<StructureSection load='2z76' size='340' side='right' caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>	+	<StructureSection load='2z76' size='340' side='right'caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [~~http~~://pdbe.org/2z76 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2z76 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2z76 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [https://pdbe.org/2z76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [https://www.ebi.ac.uk/pdbsum/2z76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z76 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 32:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Myctu]]		[[Category: Myctu]]
	[[Category: Cherney, M M]]		[[Category: Cherney, M M]]

OCA at 09:19, 17 October 2018

OCA — Wed, 17 Oct 2018 09:19:53 GMT

←Older revision		Revision as of 09:19, 17 October 2018
Line 1:		Line 1:
		+
	==X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution==		==X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution==
	<StructureSection load='2z76' size='340' side='right' caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>		<StructureSection load='2z76' size='340' side='right' caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://pdbe.org/2z76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://pdbe.org/2z76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2z76 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/2z76_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/2z76_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:29, 8 February 2016

OCA — Mon, 08 Feb 2016 13:29:18 GMT

←Older revision		Revision as of 13:29, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2z76' size='340' side='right' caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>		<StructureSection load='2z76' size='340' side='right' caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_tuberculosis Mycobacterium tuberculosis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1773 Mycobacterium tuberculosis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://pdbe.org/2z76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z76 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2z76" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mycobacterium tuberculosis~~]]	+	[[Category: Myctu]]
	[[Category: Cherney, M M]]		[[Category: Cherney, M M]]
	[[Category: Garen, C R]]		[[Category: Garen, C R]]

OCA at 10:37, 20 January 2015

OCA — Tue, 20 Jan 2015 10:37:52 GMT

←Older revision		Revision as of 10:37, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
-	[[Category: Cherney, M M.]]	+	[[Category: Cherney, M M]]
-	[[Category: Garen, C R.]]	+	[[Category: Garen, C R]]
-	[[Category: James, M N.G.]]	+	[[Category: James, M N.G]]
-	[[Category: ~~TBSGC, TB~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
	[[Category: Alpha+beta conical barrel]]		[[Category: Alpha+beta conical barrel]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
-	[[Category: Structural genomic]]
-	[[Category: Tb structural genomics consortium]]
	[[Category: Tbsgc]]		[[Category: Tbsgc]]

OCA: Protected "2z76" [edit=sysop:move=sysop]

OCA — Thu, 02 Oct 2014 05:01:53 GMT

Protected "2z76" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:01, 2 October 2014

OCA at 05:01, 2 October 2014

OCA — Thu, 02 Oct 2014 05:01:51 GMT

←Older revision		Revision as of 05:01, 2 October 2014
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-	~~{{Seed}}~~	+	==X-ray crystal structure of RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution==
-	[[~~Image:~~2z76.~~png~~\|~~left~~\|200px]]	+	<StructureSection load='2z76' size='340' side='right' caption='[[2z76]], [[Resolution\|resolution]] 1.82Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2z76]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z76 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2a15\|2a15]], [[2z77\|2z77]], [[2z7a\|2z7a]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rv0760c, MT0785 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z76 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z76 RCSB], [http://www.ebi.ac.uk/pdbsum/2z76 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z7/2z76_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the X-ray crystal structure of the Mycobacterium tuberculosis (Mtb) gene product encoded by the open reading frame Rv0760c at 1.50 A resolution by single-wavelength anomalous dispersion (SAD) phasing of diffraction data from crystals of the selenomethionine-substituted protein. Refinement against diffraction data from the native protein resulted in R(work)=19.5% and R(free)=21.4%. The X-ray crystal structure shows that the homodimeric Rv0760c polypeptide has an alpha + beta conical barrel fold placing it among many structural neighbors of the nuclear transport factor 2 family (NTF2). This family is highly conserved in terms of structure; however the substrates and individual protein functions are diverse. The structures of native Rv0760c in several different crystal forms and Rv0760c bound to 17beta-estradiol 17-hemisuccinate (EH) have also been solved and analyzed.

-	<!--	+	Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase.,Cherney MM, Garen CR, James MN Biochim Biophys Acta. 2008 Nov;1784(11):1625-32. Epub 2008 Jun 6. PMID:18589008<ref>PMID:18589008</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2z76"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_2z76\| PDB=2z76 \| SCENE= }}~~	+

-	~~===X-ray crystal structure~~ of ~~RV0760c from Mycobacterium tuberculosis at 1.82 Angstrom resolution===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_18589008}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 18589008 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+	[[Category: Mycobacterium tuberculosis]]
-	~~{{ABSTRACT_PUBMED_18589008}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~2Z76 is a 2 chains structure of sequences from [http:~~/~~/en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:18589008<~~/~~ref~~><~~references group="xtra"~~/>	+
-	[[Category: Mycobacterium tuberculosis ~~h37rv~~]]	+
	[[Category: Cherney, M M.]]		[[Category: Cherney, M M.]]
	[[Category: Garen, C R.]]		[[Category: Garen, C R.]]
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	[[Category: Tb structural genomics consortium]]		[[Category: Tb structural genomics consortium]]
	[[Category: Tbsgc]]		[[Category: Tbsgc]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:30:51 2009''

OCA at 20:30, 16 February 2009

OCA — Mon, 16 Feb 2009 20:30:53 GMT

←Older revision		Revision as of 20:30, 16 February 2009
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	==About this Structure==		==About this Structure==
-	2Z76 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].	+	2Z76 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].

	==Reference==		==Reference==
-	Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase., Cherney MM, Garen CR, James MN, Biochim Biophys Acta. 2008 Jun 6. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18589008 18589008]~~	+	<ref group="xtra">PMID:18589008</ref><references group="xtra"/>
	[[Category: Mycobacterium tuberculosis h37rv]]		[[Category: Mycobacterium tuberculosis h37rv]]
-	[[Category: Single protein]]
	[[Category: Cherney, M M.]]		[[Category: Cherney, M M.]]
	[[Category: Garen, C R.]]		[[Category: Garen, C R.]]
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	[[Category: Tbsgc]]		[[Category: Tbsgc]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Nov 12 20~~:13:~~53 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:30:51 2009''

OCA at 18:43, 12 November 2008

OCA — Wed, 12 Nov 2008 18:43:39 GMT

←Older revision		Revision as of 18:43, 12 November 2008
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	==About this Structure==		==About this Structure==
-	2Z76 is a ~~2 chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].	+	2Z76 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].

	==Reference==		==Reference==
	Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase., Cherney MM, Garen CR, James MN, Biochim Biophys Acta. 2008 Jun 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18589008 18589008]		Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase., Cherney MM, Garen CR, James MN, Biochim Biophys Acta. 2008 Jun 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18589008 18589008]
	[[Category: Mycobacterium tuberculosis h37rv]]		[[Category: Mycobacterium tuberculosis h37rv]]
		+	[[Category: Single protein]]
	[[Category: Cherney, M M.]]		[[Category: Cherney, M M.]]
	[[Category: Garen, C R.]]		[[Category: Garen, C R.]]
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	[[Category: Tbsgc]]		[[Category: Tbsgc]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 12 ~~09:54~~:13 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 12 20:13:53 2008''

OCA at 07:54, 12 November 2008

OCA — Wed, 12 Nov 2008 07:54:13 GMT

←Older revision		Revision as of 07:54, 12 November 2008
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2Z76 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].	+	2Z76 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z76 OCA].

	==Reference==		==Reference==
	Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase., Cherney MM, Garen CR, James MN, Biochim Biophys Acta. 2008 Jun 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18589008 18589008]		Crystal structure of Mycobacterium tuberculosis Rv0760c at 1.50 A resolution, a structural homolog of Delta(5)-3-ketosteroid isomerase., Cherney MM, Garen CR, James MN, Biochim Biophys Acta. 2008 Jun 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18589008 18589008]
	[[Category: Mycobacterium tuberculosis h37rv]]		[[Category: Mycobacterium tuberculosis h37rv]]
-	[[Category: Single protein]]
	[[Category: Cherney, M M.]]		[[Category: Cherney, M M.]]
	[[Category: Garen, C R.]]		[[Category: Garen, C R.]]
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	[[Category: Tbsgc]]		[[Category: Tbsgc]]

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