2zc0 - Revision history

OCA at 13:56, 13 March 2024

OCA — Wed, 13 Mar 2024 13:56:57 GMT

←Older revision		Revision as of 13:56, 13 March 2024
Line 3:		Line 3:
	<StructureSection load='2zc0' size='340' side='right'caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2zc0' size='340' side='right'caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~'caldococcus_litoralis'_z-1301 'caldococcus~~ litoralis~~' z-1301~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [~~http~~://pdbe.org/2zc0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zc0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [https://pdbe.org/2zc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [https://www.ebi.ac.uk/pdbsum/2zc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9C4M4_THELI Q9C4M4_THELI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zc0 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zc0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The crystal structure of a novel alanine:glyoxylate aminotransferase from the hyperthermophilic archaeon Thermococcus litoralis was determined at 2.3 A resolution. The asymmetric unit contains four homologous subunits and the functional tetramer is generated by noncrystallographic 222 symmetry. Although the main-chain coordinates of the monomer of the Thermococcus litoralis enzyme showed a high degree of similarity to those of aspartate aminotransferase from Thermus thermophilus HB8, the amino-acid residues involved in substrate binding in the aspartate aminotransferase are only partially conserved in the Thermococcus litoralis enzyme. This may account for the difference in the substrate specificities of the two enzymes.
-
-	Structure of an archaeal alanine:glyoxylate aminotransferase.,Sakuraba H, Yoneda K, Takeuchi K, Tsuge H, Katunuma N, Ohshima T Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):696-9. Epub 2008 May 14. PMID:18560158<ref>PMID:18560158</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2zc0" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Caldococcus litoralis z-1301]]
-	[[Category: Alanine--glyoxylate transaminase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ohshima, T]]	+	[[Category: Thermococcus litoralis]]
-	[[Category: Sakuraba, H]]	+	[[Category: Ohshima T]]
-	[[Category: Tsuge, H]]	+	[[Category: Sakuraba H]]
-	[[Category: Yoneda, K]]	+	[[Category: Tsuge H]]
-	~~[[Category: Alanine:glyoxylate aminotransferase]]~~	+	[[Category: Yoneda K]]
-	~~[[Category: Archaea]]~~	+
-	~~[[Category: Thermococcus litorali]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 12:01, 29 July 2020

OCA — Wed, 29 Jul 2020 12:01:56 GMT

←Older revision		Revision as of 12:01, 29 July 2020
Line 1:		Line 1:

	==Crystal structure of an archaeal alanine:glyoxylate aminotransferase==		==Crystal structure of an archaeal alanine:glyoxylate aminotransferase==
-	<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='2zc0' size='340' side='right'caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/'caldococcus_litoralis'_z-1301 'caldococcus litoralis' z-1301]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/'caldococcus_litoralis'_z-1301 'caldococcus litoralis' z-1301]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://pdbe.org/2zc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://pdbe.org/2zc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	[[Category: Caldococcus litoralis z-1301]]		[[Category: Caldococcus litoralis z-1301]]
	[[Category: Alanine--glyoxylate transaminase]]		[[Category: Alanine--glyoxylate transaminase]]
		+	[[Category: Large Structures]]
	[[Category: Ohshima, T]]		[[Category: Ohshima, T]]
	[[Category: Sakuraba, H]]		[[Category: Sakuraba, H]]

OCA at 07:14, 18 October 2018

OCA — Thu, 18 Oct 2018 07:14:56 GMT

←Older revision		Revision as of 07:14, 18 October 2018
Line 1:		Line 1:
		+
	==Crystal structure of an archaeal alanine:glyoxylate aminotransferase==		==Crystal structure of an archaeal alanine:glyoxylate aminotransferase==
	<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://pdbe.org/2zc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://pdbe.org/2zc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zc0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zc0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zc0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 04:53, 10 February 2016

OCA — Wed, 10 Feb 2016 04:53:48 GMT

←Older revision		Revision as of 04:53, 10 February 2016
Line 2:		Line 2:
	<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermococcus_litoralis Thermococcus~~ litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/'caldococcus_litoralis'_z-1301 'caldococcus litoralis' z-1301]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://pdbe.org/2zc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zc0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zc0" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Caldococcus litoralis z-1301]]
	[[Category: Alanine--glyoxylate transaminase]]		[[Category: Alanine--glyoxylate transaminase]]
-	[[Category: Thermococcus litoralis]]
	[[Category: Ohshima, T]]		[[Category: Ohshima, T]]
	[[Category: Sakuraba, H]]		[[Category: Sakuraba, H]]

OCA at 09:25, 20 January 2015

OCA — Tue, 20 Jan 2015 09:25:52 GMT

←Older revision		Revision as of 09:25, 20 January 2015
Line 31:		Line 31:
	[[Category: Alanine--glyoxylate transaminase]]		[[Category: Alanine--glyoxylate transaminase]]
	[[Category: Thermococcus litoralis]]		[[Category: Thermococcus litoralis]]
-	[[Category: Ohshima, T.]]	+	[[Category: Ohshima, T]]
-	[[Category: Sakuraba, H.]]	+	[[Category: Sakuraba, H]]
-	[[Category: Tsuge, H.]]	+	[[Category: Tsuge, H]]
-	[[Category: Yoneda, K.]]	+	[[Category: Yoneda, K]]
	[[Category: Alanine:glyoxylate aminotransferase]]		[[Category: Alanine:glyoxylate aminotransferase]]
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Thermococcus litorali]]		[[Category: Thermococcus litorali]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 06:38, 10 October 2014

OCA — Fri, 10 Oct 2014 06:38:10 GMT

←Older revision		Revision as of 06:38, 10 October 2014
Line 2:		Line 2:
	<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. <br>	+	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZC0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Glucokinase Glucokinase~~], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alanine--glyoxylate_transaminase Alanine--glyoxylate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.44 2.6.1.44] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:
	Structure of an archaeal alanine:glyoxylate aminotransferase.,Sakuraba H, Yoneda K, Takeuchi K, Tsuge H, Katunuma N, Ohshima T Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):696-9. Epub 2008 May 14. PMID:18560158<ref>PMID:18560158</ref>		Structure of an archaeal alanine:glyoxylate aminotransferase.,Sakuraba H, Yoneda K, Takeuchi K, Tsuge H, Katunuma N, Ohshima T Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):696-9. Epub 2008 May 14. PMID:18560158<ref>PMID:18560158</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==

OCA at 07:39, 14 May 2014

OCA — Wed, 14 May 2014 07:39:01 GMT

←Older revision		Revision as of 07:39, 14 May 2014
Line 1:		Line 1:
-	[[~~Image~~:2zc0.~~png\|left~~\|200px]]	+	==Crystal structure of an archaeal alanine:glyoxylate aminotransferase==
		+	<StructureSection load='2zc0' size='340' side='right' caption='[[2zc0]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zc0 RCSB], [http://www.ebi.ac.uk/pdbsum/2zc0 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/2zc0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of a novel alanine:glyoxylate aminotransferase from the hyperthermophilic archaeon Thermococcus litoralis was determined at 2.3 A resolution. The asymmetric unit contains four homologous subunits and the functional tetramer is generated by noncrystallographic 222 symmetry. Although the main-chain coordinates of the monomer of the Thermococcus litoralis enzyme showed a high degree of similarity to those of aspartate aminotransferase from Thermus thermophilus HB8, the amino-acid residues involved in substrate binding in the aspartate aminotransferase are only partially conserved in the Thermococcus litoralis enzyme. This may account for the difference in the substrate specificities of the two enzymes.

-	~~<!--~~	+	Structure of an archaeal alanine:glyoxylate aminotransferase.,Sakuraba H, Yoneda K, Takeuchi K, Tsuge H, Katunuma N, Ohshima T Acta Crystallogr D Biol Crystallogr. 2008 Jun;64(Pt 6):696-9. Epub 2008 May 14. PMID:18560158<ref>PMID:18560158</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2zc0"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_2zc0\| PDB=2zc0 \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~an archaeal alanine:glyoxylate aminotransferase===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_18560158}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 18560158 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_18560158}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zc0]] is a 4 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018560158<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Alanine--glyoxylate transaminase]]		[[Category: Alanine--glyoxylate transaminase]]
	[[Category: Thermococcus litoralis]]		[[Category: Thermococcus litoralis]]

OCA: Protected "2zc0" [edit=sysop:move=sysop]

OCA — Wed, 11 Apr 2012 05:58:05 GMT

Protected "2zc0" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:58, 11 April 2012

OCA at 05:58, 11 April 2012

OCA — Wed, 11 Apr 2012 05:58:03 GMT

←Older revision		Revision as of 05:58, 11 April 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2zc0.png\|left\|200px]]		[[Image:2zc0.png\|left\|200px]]

Line 12:		Line 11:
	===Crystal structure of an archaeal alanine:glyoxylate aminotransferase===		===Crystal structure of an archaeal alanine:glyoxylate aminotransferase===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18560158}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18560158 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18560158}}

	==About this Structure==		==About this Structure==
-	~~2ZC0~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA].	+	[[2zc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:018560158</ref><references group="xtra"/>
	[[Category: Alanine--glyoxylate transaminase]]		[[Category: Alanine--glyoxylate transaminase]]
	[[Category: Thermococcus litoralis]]		[[Category: Thermococcus litoralis]]
Line 24:		Line 32:
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Thermococcus litorali]]		[[Category: Thermococcus litorali]]
-		+	[[Category: Transferase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 15:35:24 2009''~~	+

OCA at 13:35, 17 February 2009

OCA — Tue, 17 Feb 2009 13:35:26 GMT

←Older revision		Revision as of 13:35, 17 February 2009
Line 1:		Line 1:
-	[[Image:2zc0.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2zc0.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2zc0\| PDB=2zc0 \| SCENE= }}		{{STRUCTURE_2zc0\| PDB=2zc0 \| SCENE= }}

-	~~'''~~Crystal structure of an archaeal alanine:glyoxylate aminotransferase~~'''~~	+	===Crystal structure of an archaeal alanine:glyoxylate aminotransferase===


	==About this Structure==		==About this Structure==
-	2ZC0 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA].	+	2ZC0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZC0 OCA].
	[[Category: Alanine--glyoxylate transaminase]]		[[Category: Alanine--glyoxylate transaminase]]
-	[[Category: Single protein]]
	[[Category: Thermococcus litoralis]]		[[Category: Thermococcus litoralis]]
	[[Category: Ohshima, T.]]		[[Category: Ohshima, T.]]
Line 24:		Line 24:
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: Thermococcus litorali]]		[[Category: Thermococcus litorali]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jun 18 12~~:07:~~16 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:35:24 2009''