2zmu - Revision history

OCA at 13:43, 1 November 2023

OCA — Wed, 01 Nov 2023 13:43:41 GMT

←Older revision		Revision as of 13:43, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2zmu' size='340' side='right'caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='2zmu' size='340' side='right'caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Funco Funco~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lithophyllon_concinna Lithophyllon concinna]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non~~-~~Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.65Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zmw\|2zmw]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 FUNCO])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [https://pdbe.org/2zmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [https://www.ebi.ac.uk/pdbsum/2zmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zmu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [https://pdbe.org/2zmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [https://www.ebi.ac.uk/pdbsum/2zmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zmu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6I7B2_LITCO Q6I7B2_LITCO]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Funco]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fukumura, E]]	+	[[Category: Lithophyllon concinna]]
-	[[Category: Karasawa, S]]	+	[[Category: Fukumura E]]
-	[[Category: Kikuchi, A]]	+	[[Category: Karasawa S]]
-	[[Category: Miyawaki, A]]	+	[[Category: Kikuchi A]]
-	[[Category: Mizuno, H]]	+	[[Category: Miyawaki A]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Mizuno H]]
-	[[Category: Shiro, Y]]	+	[[Category: Shiro Y]]
-	~~[[Category: Gfp-like protein]]~~	+
-	~~[[Category: Luminescent protein]]~~	+
-	~~[[Category: National project on protein structural and functional analyse]]~~	+
-	~~[[Category: Nppsfa]]~~	+
-	~~[[Category: Rsgi~~]]	+

OCA at 17:33, 15 December 2021

OCA — Wed, 15 Dec 2021 17:33:08 GMT

←Older revision		Revision as of 17:33, 15 December 2021
Line 1:		Line 1:

	==Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1==		==Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1==
-	<StructureSection load='2zmu' size='340' side='right' caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>	+	<StructureSection load='2zmu' size='340' side='right'caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Funco Funco]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Funco Funco]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zmw\|2zmw]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 FUNCO])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 FUNCO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [~~http~~://pdbe.org/2zmu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zmu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zmu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [https://pdbe.org/2zmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [https://www.ebi.ac.uk/pdbsum/2zmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zmu ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Funco]]		[[Category: Funco]]
		+	[[Category: Large Structures]]
	[[Category: Fukumura, E]]		[[Category: Fukumura, E]]
	[[Category: Karasawa, S]]		[[Category: Karasawa, S]]

OCA at 06:54, 18 October 2018

OCA — Thu, 18 Oct 2018 06:54:45 GMT

←Older revision		Revision as of 06:54, 18 October 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1==		==Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1==
	<StructureSection load='2zmu' size='340' side='right' caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='2zmu' size='340' side='right' caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 FUNCO])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 FUNCO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://pdbe.org/2zmu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://pdbe.org/2zmu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zmu ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zm/2zmu_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zm/2zmu_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:33, 8 February 2016

OCA — Mon, 08 Feb 2016 05:33:18 GMT

←Older revision		Revision as of 05:33, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2zmu' size='340' side='right' caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>		<StructureSection load='2zmu' size='340' side='right' caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Verrillofungia_concinna Verrillofungia concinna~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Funco Funco]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 ~~Verrillofungia concinna~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 FUNCO])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://pdbe.org/2zmu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zmu ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zmu" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Verrillofungia concinna~~]]	+	[[Category: Funco]]
	[[Category: Fukumura, E]]		[[Category: Fukumura, E]]
	[[Category: Karasawa, S]]		[[Category: Karasawa, S]]

OCA at 10:03, 20 January 2015

OCA — Tue, 20 Jan 2015 10:03:39 GMT

←Older revision		Revision as of 10:03, 20 January 2015
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Verrillofungia concinna]]		[[Category: Verrillofungia concinna]]
-	[[Category: Fukumura, E.]]	+	[[Category: Fukumura, E]]
-	[[Category: Karasawa, S.]]	+	[[Category: Karasawa, S]]
-	[[Category: Kikuchi, A.]]	+	[[Category: Kikuchi, A]]
-	[[Category: Miyawaki, A.]]	+	[[Category: Miyawaki, A]]
-	[[Category: Mizuno, H.]]	+	[[Category: Mizuno, H]]
-	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Shiro, Y.]]	+	[[Category: Shiro, Y]]
	[[Category: Gfp-like protein]]		[[Category: Gfp-like protein]]
	[[Category: Luminescent protein]]		[[Category: Luminescent protein]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
-	[[Category: Riken structural genomics/proteomics initiative]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
-	[[Category: Structural genomic]]

OCA at 05:51, 10 October 2014

OCA — Fri, 10 Oct 2014 05:51:29 GMT

←Older revision		Revision as of 05:51, 10 October 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 Verrillofungia concinna])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 Verrillofungia concinna])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 24:
	Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange.,Kikuchi A, Fukumura E, Karasawa S, Mizuno H, Miyawaki A, Shiro Y Biochemistry. 2008 Oct 10. PMID:18844376<ref>PMID:18844376</ref>		Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange.,Kikuchi A, Fukumura E, Karasawa S, Mizuno H, Miyawaki A, Shiro Y Biochemistry. 2008 Oct 10. PMID:18844376<ref>PMID:18844376</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==

OCA at 11:06, 14 May 2014

OCA — Wed, 14 May 2014 11:06:28 GMT

←Older revision		Revision as of 11:06, 14 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2zmu.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1==
		+	<StructureSection load='2zmu' size='340' side='right' caption='[[2zmu]], [[Resolution\|resolution]] 1.65Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zmu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZMU FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CFY:[(4Z)-2-{(2R)-2-[(1S)-1-AMINO-2-PHENYLETHYL]-2-HYDROXY-2,5-DIHYDRO-1,3-THIAZOL-4-YL}-4-(4-HYDROXYBENZYLIDENE)-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL]ACETIC+ACID'>CFY</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zmw\|2zmw]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mKO ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=496660 Verrillofungia concinna])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zmu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zmu RCSB], [http://www.ebi.ac.uk/pdbsum/2zmu PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zm/2zmu_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Monomeric Kusabira Orange (mKO) is a green fluorescent protein (GFP)-like protein that emits orange light at a peak of 559 nm. We analyzed its X-ray structure at 1.65 A and found a novel three-ring chromophore that developed autocatalytically from a Cys65-Tyr66-Glu67 tripeptide in which the side chain of Cys65 formed the third 2-hydroxy-3-thiazoline ring. As a result, the chromophore contained the CNCOH group at the 2-position of the imidazolinone moiety such that the conjugated pi-electron system of the chromophore was more extended than that of GFP but less extended than that of the Discosoma sp. red fluorescent protein (DsRed). Since a sulfur atom has potent nucleophilic character, the third 3-thiazoline ring is rapidly and completely cyclized. Furthermore, our structure reveals the presence of a pi-pi stacking interaction between His197 and the chromophore as well as a pi-cation interaction between Arg69 and the chromophore. These structural findings are sufficient to account for the orange emission, pH tolerance, and photostability of mKO.

-	<!--	+	Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange.,Kikuchi A, Fukumura E, Karasawa S, Mizuno H, Miyawaki A, Shiro Y Biochemistry. 2008 Oct 10. PMID:18844376<ref>PMID:18844376</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2zmu", creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded)~~,	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2zmu\| PDB=2zmu \| SCENE= }}~~	+

-	~~===Crystal Structure~~ of ~~Monomeric Kusabira-Orange (MKO), Orange-Emitting GFP-like Protein, at pH 9.1===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_18844376}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 18844376 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_18844376}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zmu]] is a 1 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018844376<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Verrillofungia concinna]]		[[Category: Verrillofungia concinna]]
	[[Category: Fukumura, E.]]		[[Category: Fukumura, E.]]

OCA: Protected "2zmu" [edit=sysop:move=sysop]

OCA — Wed, 02 May 2012 18:29:04 GMT

Protected "2zmu" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:29, 2 May 2012

OCA at 18:29, 2 May 2012

OCA — Wed, 02 May 2012 18:29:01 GMT

←Older revision		Revision as of 18:29, 2 May 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2zmu.png\|left\|200px]]		[[Image:2zmu.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2ZMU~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA].	+	[[2zmu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ejo 2ejo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18844376~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018844376</ref><references group="xtra"/>
	[[Category: Verrillofungia concinna]]		[[Category: Verrillofungia concinna]]
	[[Category: Fukumura, E.]]		[[Category: Fukumura, E.]]
Line 39:		Line 38:
	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:11:14 2009''

OCA at 17:11, 16 February 2009

OCA — Mon, 16 Feb 2009 17:11:16 GMT

←Older revision		Revision as of 17:11, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2ZMU is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA].	+	2ZMU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Verrillofungia_concinna Verrillofungia concinna]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMU OCA].

	==Reference==		==Reference==
-	Structural Characterization of a Thiazoline-Containing Chromophore in an Orange Fluorescent Protein, Monomeric Kusabira Orange., Kikuchi A, Fukumura E, Karasawa S, Mizuno H, Miyawaki A, Shiro Y, Biochemistry. 2008 Oct 10. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18844376 18844376]~~	+	<ref group="xtra">PMID:18844376</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Verrillofungia concinna]]		[[Category: Verrillofungia concinna]]
	[[Category: Fukumura, E.]]		[[Category: Fukumura, E.]]
Line 41:		Line 40:
	[[Category: Structural genomic]]		[[Category: Structural genomic]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Nov 5 10~~:35:~~52 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 19:11:14 2009''