2zqx - Revision history

OCA at 13:50, 1 November 2023

OCA — Wed, 01 Nov 2023 13:50:14 GMT

←Older revision		Revision as of 13:50, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2zqx' size='340' side='right'caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>		<StructureSection load='2zqx' size='340' side='right'caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.37Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[2zqj\|2zqj]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">cypC, CYP152A1, BSU02100 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [https://pdbe.org/2zqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [https://www.ebi.ac.uk/pdbsum/2zqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [https://pdbe.org/2zqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [https://www.ebi.ac.uk/pdbsum/2zqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CYPC_BACSU CYPC_BACSU]] Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.	+	[https://www.uniprot.org/uniprot/CYPC_BACSU CYPC_BACSU] Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835~~]]	+	[[Category: Bacillus subtilis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fujishiro, T]]	+	[[Category: Fujishiro T]]
-	[[Category: Hirose, T]]	+	[[Category: Hirose T]]
-	[[Category: Nagano, S]]	+	[[Category: Nagano S]]
-	[[Category: Shiro, Y]]	+	[[Category: Shiro Y]]
-	[[Category: Shoji, O]]	+	[[Category: Shoji O]]
-	[[Category: Watanabe, Y]]	+	[[Category: Watanabe Y]]
-	~~[[Category: Heme]]~~	+
-	~~[[Category: Heme protein]]~~	+
-	~~[[Category: Heptanoic acid]]~~	+
-	~~[[Category: Iron]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Monooxygenase]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Peroxigenese~~]]	+

OCA at 17:35, 15 December 2021

OCA — Wed, 15 Dec 2021 17:35:40 GMT

←Older revision		Revision as of 17:35, 15 December 2021
Line 1:		Line 1:

	==Cytochrome P450BSbeta cocrystallized with heptanoic acid==		==Cytochrome P450BSbeta cocrystallized with heptanoic acid==
-	<StructureSection load='2zqx' size='340' side='right' caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>	+	<StructureSection load='2zqx' size='340' side='right'caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zqj\|2zqj]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [~~http~~://pdbe.org/2zqx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zqx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [https://pdbe.org/2zqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [https://www.ebi.ac.uk/pdbsum/2zqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CYPC_BACSU CYPC_BACSU]] Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.	+	[[https://www.uniprot.org/uniprot/CYPC_BACSU CYPC_BACSU]] Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Cytochrome P450\|Cytochrome P450]]	+	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Vibrio subtilis ehrenberg 1835]]		[[Category: Vibrio subtilis ehrenberg 1835]]
		+	[[Category: Large Structures]]
	[[Category: Fujishiro, T]]		[[Category: Fujishiro, T]]
	[[Category: Hirose, T]]		[[Category: Hirose, T]]

OCA at 07:12, 18 October 2018

OCA — Thu, 18 Oct 2018 07:12:04 GMT

←Older revision		Revision as of 07:12, 18 October 2018
Line 1:		Line 1:
		+
	==Cytochrome P450BSbeta cocrystallized with heptanoic acid==		==Cytochrome P450BSbeta cocrystallized with heptanoic acid==
	<StructureSection load='2zqx' size='340' side='right' caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>		<StructureSection load='2zqx' size='340' side='right' caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "~~Bacillus globigii~~" ~~Migula 1900~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://pdbe.org/2zqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://pdbe.org/2zqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqx ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zq/2zqx_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zq/2zqx_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus globigii migula 1900~~]]	+	[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Fujishiro, T]]		[[Category: Fujishiro, T]]
	[[Category: Hirose, T]]		[[Category: Hirose, T]]

OCA at 18:43, 7 February 2016

OCA — Sun, 07 Feb 2016 18:43:39 GMT

←Older revision		Revision as of 18:43, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='2zqx' size='340' side='right' caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>		<StructureSection load='2zqx' size='340' side='right' caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_subtilis Bacillus subtilis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus ~~subtilis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://pdbe.org/2zqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zqx ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zqx" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus ~~subtilis~~]]	+	[[Category: Bacillus globigii migula 1900]]
	[[Category: Fujishiro, T]]		[[Category: Fujishiro, T]]
	[[Category: Hirose, T]]		[[Category: Hirose, T]]

OCA at 17:31, 24 December 2014

OCA — Wed, 24 Dec 2014 17:31:51 GMT

←Older revision		Revision as of 17:31, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CYPC_BACSU CYPC_BACSU]] Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
-	[[Category: Fujishiro, T.]]	+	[[Category: Fujishiro, T]]
-	[[Category: Hirose, T.]]	+	[[Category: Hirose, T]]
-	[[Category: Nagano, S.]]	+	[[Category: Nagano, S]]
-	[[Category: Shiro, Y.]]	+	[[Category: Shiro, Y]]
-	[[Category: Shoji, O.]]	+	[[Category: Shoji, O]]
-	[[Category: Watanabe, Y.]]	+	[[Category: Watanabe, Y]]
	[[Category: Heme]]		[[Category: Heme]]
	[[Category: Heme protein]]		[[Category: Heme protein]]

OCA at 06:47, 29 September 2014

OCA — Mon, 29 Sep 2014 06:47:54 GMT

←Older revision		Revision as of 06:47, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2zqx.~~png~~\|~~left~~\|200px]]	+	==Cytochrome P450BSbeta cocrystallized with heptanoic acid==
		+	<StructureSection load='2zqx' size='340' side='right' caption='[[2zqx]], [[Resolution\|resolution]] 2.37Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZQX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zqj\|2zqj]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cypC, CYP152A1, BSU02100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zqx RCSB], [http://www.ebi.ac.uk/pdbsum/2zqx PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zq/2zqx_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cytochrome P450(BSbeta), a H(2)O(2)-dependent cytochrome P450 catalyzing the hydroxylation of long-alkyl-chain fatty acids, lacks the general acid-base residue around the heme, which is indispensable for the efficient generation of the active species using H(2)O(2). On the basis of the crystal structure of the palmitic acid bound form of cytochrome P450(BSbeta), it was suggested that the role of the general acid-base function was provided by the carboxylate group of fatty acids. The participation of the carboxylate group of the substrate was supported by the fact that cytochrome P450(BSbeta) can catalyze oxidations of nonnatural substrates such as styrene and ethylbenzene in the presence of a series of short-alkyl-chain carboxylic acids as a dummy molecule of fatty acid. We refer to a series of short-alkyl-chain carboxylic acids as a "decoy molecule". As shown here, we have clarified the crystal structure of the decoy-molecule-bound form and elucidated that the location of its carboxylate group is virtually the same as that of palmitic acid in the heme cavity, indicating that the carboxylate group of the decoy molecule serves as the general acid-base catalyst. This result further confirms that the role of the acid-base function is satisfied by the carboxylate group of the substrates. In addition, the structure analysis of the substrate-free form has clarified that no remarkable structural change is induced by the binding of the decoy molecule as well as fatty acid. Consequently, whether the carboxylate group is positioned in the active site provides the switching mechanism of the catalytic cycle of cytochrome P450(BSbeta).

-	~~{{STRUCTURE_2zqx\| PDB=2zqx \| SCENE= }}~~	+	Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis.,Shoji O, Fujishiro T, Nagano S, Tanaka S, Hirose T, Shiro Y, Watanabe Y J Biol Inorg Chem. 2010 Aug 10. PMID:20697922<ref>PMID:20697922</ref>

-	~~===Cytochrome P450BSbeta cocrystallized with heptanoic acid===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20697922}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zqx]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_subtilis Bacillus subtilis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA].~~	+

	==See Also==		==See Also==
	*[[Cytochrome P450\|Cytochrome P450]]		*[[Cytochrome P450\|Cytochrome P450]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020697922<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Fujishiro, T.]]		[[Category: Fujishiro, T.]]

OCA at 07:33, 20 October 2012

OCA — Sat, 20 Oct 2012 07:33:19 GMT

←Older revision		Revision as of 07:33, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2zqx]] is a 3 chain structure ~~of [[Cytochrome P450]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA].	+	[[2zqx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA].

	==See Also==		==See Also==

OCA at 16:42, 25 July 2012

OCA — Wed, 25 Jul 2012 16:42:10 GMT

←Older revision		Revision as of 16:42, 25 July 2012
Line 1:		Line 1:
	[[Image:2zqx.png\|left\|200px]]		[[Image:2zqx.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2zqx", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2zqx\| PDB=2zqx \| SCENE= }}		{{STRUCTURE_2zqx\| PDB=2zqx \| SCENE= }}

	===Cytochrome P450BSbeta cocrystallized with heptanoic acid===		===Cytochrome P450BSbeta cocrystallized with heptanoic acid===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20697922}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20697922 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20697922}}		{{ABSTRACT_PUBMED_20697922}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Cytochrome P450]]	+	*[[Cytochrome P450\|Cytochrome P450]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20697922~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020697922</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Fujishiro, T.]]		[[Category: Fujishiro, T.]]

OCA: Protected "2zqx" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 08:49:02 GMT

Protected "2zqx" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:49, 26 December 2010

OCA at 08:49, 26 December 2010

OCA — Sun, 26 Dec 2010 08:49:01 GMT

←Older revision		Revision as of 08:49, 26 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2zqx.png\|left\|200px]]		[[Image:2zqx.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2ZQX~~ is a 3 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA].	+	[[2zqx]] is a 3 chain structure of [[Cytochrome P450]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQX OCA].
		+
		+	==See Also==
		+	*[[Cytochrome P450]]

	==Reference==		==Reference==
Line 39:		Line 41:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Peroxigenese]]		[[Category: Peroxigenese]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:24:53 2010''