2zua - Revision history

OCA at 13:55, 1 November 2023

OCA — Wed, 01 Nov 2023 13:55:02 GMT

←Older revision		Revision as of 13:55, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2zua' size='340' side='right'caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>		<StructureSection load='2zua' size='340' side='right'caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_700850 Atcc 700850~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ndk (~~[~~https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=182779 ATCC 700850])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.59Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [https://pdbe.org/2zua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [https://www.ebi.ac.uk/pdbsum/2zua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zua ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [https://pdbe.org/2zua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [https://www.ebi.ac.uk/pdbsum/2zua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zua ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q401C5_9EURY Q401C5_9EURY]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).[HAMAP-Rule:MF_00451]	+	[https://www.uniprot.org/uniprot/Q401C5_9EURY Q401C5_9EURY] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).[HAMAP-Rule:MF_00451]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 700850~~]]	+	[[Category: Haloarcula quadrata]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ichimura, T]]	+	[[Category: Ichimura T]]
-	[[Category: Miyazono, K]]	+	[[Category: Miyazono K]]
-	[[Category: Nagata, K]]	+	[[Category: Nagata K]]
-	[[Category: Ohtsuka, J]]	+	[[Category: Ohtsuka J]]
-	[[Category: Okai, M]]	+	[[Category: Okai M]]
-	[[Category: Tanokura, M]]	+	[[Category: Tanokura M]]
-	[[Category: Yamamura, A]]	+	[[Category: Yamamura A]]
-	~~[[Category: Ferredoxin fold]]~~	+
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Kpn loop]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 17:38, 15 December 2021

OCA — Wed, 15 Dec 2021 17:38:11 GMT

←Older revision		Revision as of 17:38, 15 December 2021
Line 1:		Line 1:

	==Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata==		==Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata==
-	<StructureSection load='2zua' size='340' side='right' caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>	+	<StructureSection load='2zua' size='340' side='right'caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_700850 Atcc 700850]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_700850 Atcc 700850]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 ATCC 700850])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 ATCC 700850])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [~~http~~://pdbe.org/2zua PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zua PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zua ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [https://pdbe.org/2zua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [https://www.ebi.ac.uk/pdbsum/2zua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zua ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/Q401C5_9EURY Q401C5_9EURY]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).[HAMAP-Rule:MF_00451]	+	[[https://www.uniprot.org/uniprot/Q401C5_9EURY Q401C5_9EURY]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).[HAMAP-Rule:MF_00451]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Nucleoside diphosphate kinase\|Nucleoside diphosphate kinase]]	+	*[[Nucleoside diphosphate kinase 3D structures\|Nucleoside diphosphate kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 700850]]		[[Category: Atcc 700850]]
		+	[[Category: Large Structures]]
	[[Category: Ichimura, T]]		[[Category: Ichimura, T]]
	[[Category: Miyazono, K]]		[[Category: Miyazono, K]]

OCA at 07:18, 18 October 2018

OCA — Thu, 18 Oct 2018 07:18:35 GMT

←Older revision		Revision as of 07:18, 18 October 2018
Line 1:		Line 1:
		+
	==Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata==		==Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata==
	<StructureSection load='2zua' size='340' side='right' caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>		<StructureSection load='2zua' size='340' side='right' caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700850 Atcc 700850]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700850 Atcc 700850]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 ATCC 700850])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 ATCC 700850])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://pdbe.org/2zua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://pdbe.org/2zua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zua ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zua_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zua_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 08:08, 9 February 2016

OCA — Tue, 09 Feb 2016 08:08:16 GMT

←Older revision		Revision as of 08:08, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2zua' size='340' side='right' caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>		<StructureSection load='2zua' size='340' side='right' caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Haloarcula_quadrata Haloarcula quadrata~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_700850 Atcc 700850]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 ~~Haloarcula quadrata~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 ATCC 700850])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://pdbe.org/2zua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zua ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zua" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Haloarcula quadrata~~]]	+	[[Category: Atcc 700850]]
	[[Category: Ichimura, T]]		[[Category: Ichimura, T]]
	[[Category: Miyazono, K]]		[[Category: Miyazono, K]]

OCA at 05:35, 25 December 2014

OCA — Thu, 25 Dec 2014 05:35:52 GMT

←Older revision		Revision as of 05:35, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 Haloarcula quadrata])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 Haloarcula quadrata])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q401C5_9EURY Q401C5_9EURY]] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).[HAMAP-Rule:MF_00451]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Haloarcula quadrata]]		[[Category: Haloarcula quadrata]]
-	[[Category: Ichimura, T.]]	+	[[Category: Ichimura, T]]
-	[[Category: Miyazono, K.]]	+	[[Category: Miyazono, K]]
-	[[Category: Nagata, K.]]	+	[[Category: Nagata, K]]
-	[[Category: Ohtsuka, J.]]	+	[[Category: Ohtsuka, J]]
-	[[Category: Okai, M.]]	+	[[Category: Okai, M]]
-	[[Category: Tanokura, M.]]	+	[[Category: Tanokura, M]]
-	[[Category: Yamamura, A.]]	+	[[Category: Yamamura, A]]
	[[Category: Ferredoxin fold]]		[[Category: Ferredoxin fold]]
	[[Category: Kinase]]		[[Category: Kinase]]
	[[Category: Kpn loop]]		[[Category: Kpn loop]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 07:52, 29 September 2014

OCA — Mon, 29 Sep 2014 07:52:55 GMT

←Older revision		Revision as of 07:52, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2zua.~~png\|left~~\|200px]]	+	==Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata==
		+	<StructureSection load='2zua' size='340' side='right' caption='[[2zua]], [[Resolution\|resolution]] 2.59Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ndk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=182779 Haloarcula quadrata])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zua OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zua RCSB], [http://www.ebi.ac.uk/pdbsum/2zua PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zua_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Nucleoside diphosphate kinases from haloarchaea Haloarcula quadrata (NDK-q) and H. sinaiiensis (NDK-s) are identical except for one out of 154 residues, i.e., Arg(31) in NDK-q and Cys(31) in NDK-s. However, the salt-dependent activity profiles of NDK-q and NDK-s are quite different: the optimal NaCl concentrations of NDK-q and NDK-s are 1 M and 2 M, respectively. We analyzed the relationships of the secondary, tertiary, and quaternary structures and NDK activity of these NDKs at various salt concentrations, and revealed that 1), NDK-q is present as a hexamer under a wide range of salt concentrations (0.2-4 M NaCl), whereas NDK-s is present as a hexamer at an NaCl concentration above 2 M and as a dimer at NaCl concentrations below 1 M; 2), dimeric NDK-s has lower activity than hexameric NDK-s; and 3), dimeric NDK-s has higher helicity than hexameric NDK-s. We also determined the crystal structure of hexameric NDK-q, and revealed that Arg(31) plays an important role in stabilizing the hexamer. Thus the substitution of Arg (as in NDK-q) to Cys (as in NDK-s) at position 31 destabilizes the hexameric assembly, and causes dissociation to less active dimers at low salt concentrations.

-	~~{{STRUCTURE_2zua\| PDB=2zua \| SCENE= }}~~	+	Molecular mechanism of distinct salt-dependent enzyme activity of two halophilic nucleoside diphosphate kinases.,Yamamura A, Ichimura T, Kamekura M, Mizuki T, Usami R, Makino T, Ohtsuka J, Miyazono K, Okai M, Nagata K, Tanokura M Biophys J. 2009 Jun 3;96(11):4692-700. PMID:19486691<ref>PMID:19486691</ref>

-	~~===Crystal structure~~ of ~~nucleoside diphosphate kinase from Haloarcula quadrata===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19486691}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zua]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Haloarcula_quadrata Haloarcula quadrata]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA].~~	+

	==See Also==		==See Also==
	*[[Nucleoside diphosphate kinase\|Nucleoside diphosphate kinase]]		*[[Nucleoside diphosphate kinase\|Nucleoside diphosphate kinase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019486691<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Haloarcula quadrata]]		[[Category: Haloarcula quadrata]]
	[[Category: Ichimura, T.]]		[[Category: Ichimura, T.]]

OCA at 13:13, 20 October 2012

OCA — Sat, 20 Oct 2012 13:13:25 GMT

←Older revision		Revision as of 13:13, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2zua]] is a 4 chain structure ~~of [[Nucleoside diphosphate kinase]]~~ with sequence from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA].	+	[[2zua]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA].

	==See Also==		==See Also==

OCA: Protected "2zua" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 11:16:59 GMT

Protected "2zua" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:16, 26 July 2012

OCA at 11:16, 26 July 2012

OCA — Thu, 26 Jul 2012 11:16:57 GMT

←Older revision		Revision as of 11:16, 26 July 2012
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-	{{Seed}}
	[[Image:2zua.png\|left\|200px]]		[[Image:2zua.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2zua", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2zua\| PDB=2zua \| SCENE= }}		{{STRUCTURE_2zua\| PDB=2zua \| SCENE= }}

	===Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata===		===Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19486691}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19486691 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19486691}}		{{ABSTRACT_PUBMED_19486691}}

	==About this Structure==		==About this Structure==
-	~~2ZUA~~ is a 4 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA].	+	[[2zua]] is a 4 chain structure of [[Nucleoside diphosphate kinase]] with sequence from [http://en.wikipedia.org/wiki/Haloarcula_quadrata Haloarcula quadrata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUA OCA].
		+
		+	==See Also==
		+	*[[Nucleoside diphosphate kinase\|Nucleoside diphosphate kinase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19486691~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019486691</ref><references group="xtra"/>
	[[Category: Haloarcula quadrata]]		[[Category: Haloarcula quadrata]]
	[[Category: Ichimura, T.]]		[[Category: Ichimura, T.]]
Line 36:		Line 27:
	[[Category: Kpn loop]]		[[Category: Kpn loop]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:22:54 2009''

OCA at 16:22, 21 September 2009

OCA — Mon, 21 Sep 2009 16:22:56 GMT

←Older revision		Revision as of 16:22, 21 September 2009
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	===Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata===		===Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19486691}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19486691 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19486691}}

	==About this Structure==		==About this Structure==
Line 31:		Line 37:
	[[Category: Transferase]]		[[Category: Transferase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 16:43:10 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:22:54 2009''