2zuk - Revision history

OCA at 13:55, 1 November 2023

OCA — Wed, 01 Nov 2023 13:55:29 GMT

←Older revision		Revision as of 13:55, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2zuk' size='340' side='right'caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='2zuk' size='340' side='right'caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~'achromobacter_obae' 'achromobacter~~ obae']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ICC:AZEPAN~~-2~~-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.41Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3dxv\|3dxv]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[http~~:~~//en.wikipedia.org/wiki/2~~-~~aminohexano~~-~~6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [https://pdbe.org/2zuk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [https://www.ebi.ac.uk/pdbsum/2zuk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuk ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [~~http~~://pdbe.org/2zuk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zuk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuk ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ACLR_ACHOB ACLR_ACHOB] catalyzes the interconversion of L-alpha-amino-epsilon-caprolactam and D-alpha-amino-epsilon-caprolactam.<ref>PMID:19146406</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]
-	[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Asano, Y]]	+	[[Category: Asano Y]]
-	[[Category: Komeda, H]]	+	[[Category: Komeda H]]
-	[[Category: Okazaki, S]]	+	[[Category: Okazaki S]]
-	[[Category: Suzuki, A]]	+	[[Category: Suzuki A]]
-	[[Category: Yamane, T]]	+	[[Category: Yamane T]]
-	~~[[Category: Fold-type1]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Pyridoxal phosphate]]~~	+
-	~~[[Category: Pyridoxal-5'-phosphate dependent racemase~~]]	+

OCA at 12:10, 29 July 2020

OCA — Wed, 29 Jul 2020 12:10:05 GMT

←Older revision		Revision as of 12:10, 29 July 2020
Line 1:		Line 1:

	==The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)==		==The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)==
-	<StructureSection load='2zuk' size='340' side='right' caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>	+	<StructureSection load='2zuk' size='340' side='right'caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'achromobacter_obae' 'achromobacter obae']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'achromobacter_obae' 'achromobacter obae']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://pdbe.org/2zuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuk ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://pdbe.org/2zuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuk ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 34:		Line 34:
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]
	[[Category: 2-aminohexano-6-lactam racemase]]		[[Category: 2-aminohexano-6-lactam racemase]]
		+	[[Category: Large Structures]]
	[[Category: Asano, Y]]		[[Category: Asano, Y]]
	[[Category: Komeda, H]]		[[Category: Komeda, H]]

OCA at 07:38, 18 October 2018

OCA — Thu, 18 Oct 2018 07:38:41 GMT

←Older revision		Revision as of 07:38, 18 October 2018
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zuk_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zuk_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:27, 11 August 2016

OCA — Thu, 11 Aug 2016 11:27:31 GMT

←Older revision		Revision as of 11:27, 11 August 2016
Line 1:		Line 1:
		+
	==The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)==		==The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)==
	<StructureSection load='2zuk' size='340' side='right' caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>		<StructureSection load='2zuk' size='340' side='right' caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Achromobacter_obae Achromobacter~~ obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'achromobacter_obae' 'achromobacter obae']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://pdbe.org/2zuk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zuk ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zuk ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zuk" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]
		+	[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Asano, Y]]		[[Category: Asano, Y]]
	[[Category: Komeda, H]]		[[Category: Komeda, H]]

OCA at 08:46, 20 January 2015

OCA — Tue, 20 Jan 2015 08:46:42 GMT

←Older revision		Revision as of 08:46, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	[[Category: 2-aminohexano-6-lactam racemase]]		[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]
-	[[Category: Asano, Y.]]	+	[[Category: Asano, Y]]
-	[[Category: Komeda, H.]]	+	[[Category: Komeda, H]]
-	[[Category: Okazaki, S.]]	+	[[Category: Okazaki, S]]
-	[[Category: Suzuki, A.]]	+	[[Category: Suzuki, A]]
-	[[Category: Yamane, T.]]	+	[[Category: Yamane, T]]
	[[Category: Fold-type1]]		[[Category: Fold-type1]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]
	[[Category: Pyridoxal-5'-phosphate dependent racemase]]		[[Category: Pyridoxal-5'-phosphate dependent racemase]]

OCA at 05:14, 2 October 2014

OCA — Thu, 02 Oct 2014 05:14:28 GMT

←Older revision		Revision as of 05:14, 2 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2zuk.~~png~~\|~~left~~\|200px]]	+	==The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)==
		+	<StructureSection load='2zuk' size='340' side='right' caption='[[2zuk]], [[Resolution\|resolution]] 2.41Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZUK FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ICC:AZEPAN-2-ONE'>ICC</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dxv\|3dxv]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-aminohexano-6-lactam_racemase 2-aminohexano-6-lactam racemase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.15 5.1.1.15] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zuk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zuk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zuk RCSB], [http://www.ebi.ac.uk/pdbsum/2zuk PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zu/2zuk_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Alpha-amino-epsilon-caprolactam (ACL) racemase (ACLR) from Achromobacter obae catalyzes the interconversion of l- and d-ACL. ACLR belongs to the fold-type I group of pyridoxal 5'-phosphate (PLP) dependent enzymes. In this study, the first crystal structures of a fold-type I racemase are solved for the native form and epsilon-caprolactam-complexed form of ACLR at 2.21 and 2.40 A resolution, respectively. Based on the location of epsilon-caprolactam in the complex structure, the substrate-binding site is assigned between Trp49 and Tyr137. The carboxyl group of Asp210 is a reasonable candidate that recognizes the nitrogen atom of a lactam or amide in the substrate. Based on a structural comparison with fold-type III alanine racemase, Tyr137 is potentially the acid/base catalytic residue that is essential for the two-base racemization mechanism. The overall structure of ACLR is similar to that of fold-type I enzymes. A structural comparison with these enzymes explains the different reaction specificities.

-	~~{{STRUCTURE_2zuk\| PDB=2zuk \| SCENE= }}~~	+	The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae.,Okazaki S, Suzuki A, Mizushima T, Kawano T, Komeda H, Asano Y, Yamane T Biochemistry. 2009 Feb 10;48(5):941-50. PMID:19146406<ref>PMID:19146406</ref>

-	~~===The crystal structure~~ of ~~alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19146406}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2zuk]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Achromobacter_obae Achromobacter obae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019146406<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: 2-aminohexano-6-lactam racemase]]		[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]

OCA: Protected "2zuk" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 21:11:48 GMT

Protected "2zuk" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:11, 7 January 2013

OCA at 21:11, 7 January 2013

OCA — Mon, 07 Jan 2013 21:11:44 GMT

←Older revision		Revision as of 21:11, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2zuk.png\|left\|200px]]		[[Image:2zuk.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2zuk", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2zuk\| PDB=2zuk \| SCENE= }}		{{STRUCTURE_2zuk\| PDB=2zuk \| SCENE= }}

	===The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)===		===The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19146406}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19146406 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19146406}}		{{ABSTRACT_PUBMED_19146406}}

	==About this Structure==		==About this Structure==
-	~~2ZUK~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA].	+	[[2zuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19146406~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019146406</ref><references group="xtra"/>
	[[Category: 2-aminohexano-6-lactam racemase]]		[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]
Line 35:		Line 23:
	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]
	[[Category: Pyridoxal-5'-phosphate dependent racemase]]		[[Category: Pyridoxal-5'-phosphate dependent racemase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:46:26 2010''

OCA at 04:37, 29 September 2010

OCA — Wed, 29 Sep 2010 04:37:12 GMT

←Older revision		Revision as of 04:37, 29 September 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:2zuk.~~jpg~~\|left\|200px]]	+	[[Image:2zuk.png\|left\|200px]]

	<!--		<!--
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2ZUK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA].	+	2ZUK is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:19146406</ref><references group="xtra"/>		<ref group="xtra">PMID:19146406</ref><references group="xtra"/>
		+	[[Category: 2-aminohexano-6-lactam racemase]]
	[[Category: Achromobacter obae]]		[[Category: Achromobacter obae]]
	[[Category: Asano, Y.]]		[[Category: Asano, Y.]]
Line 35:		Line 36:
	[[Category: Pyridoxal-5'-phosphate dependent racemase]]		[[Category: Pyridoxal-5'-phosphate dependent racemase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 18 09~~:06:~~58 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:46:26 2010''

OCA at 07:06, 18 February 2009

OCA — Wed, 18 Feb 2009 07:06:58 GMT

←Older revision		Revision as of 07:06, 18 February 2009
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:2zuk.jpg\|left\|200px]]

-	The ~~entry 2zuk~~ is ~~ON HOLD~~ ~~until Oct 18 2010~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2zuk", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2zuk\| PDB=2zuk \| SCENE= }}

-	~~Authors: Okazaki, S., Suzuki, A., Komeda, H., Asano, Y., Yamane, T.~~	+	===The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)===

-	Description: The crystal structure of alpha-amino-epsilon-caprolactam racemase from Achromobacter obae complexed with epsilon caprolactam (different binding mode)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 29 10~~:21:~~39 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19146406}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19146406 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19146406}}
		+
		+	==About this Structure==
		+	2ZUK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Achromobacter_obae Achromobacter obae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZUK OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19146406</ref><references group="xtra"/>
		+	[[Category: Achromobacter obae]]
		+	[[Category: Asano, Y.]]
		+	[[Category: Komeda, H.]]
		+	[[Category: Okazaki, S.]]
		+	[[Category: Suzuki, A.]]
		+	[[Category: Yamane, T.]]
		+	[[Category: Fold-type1]]
		+	[[Category: Isomerase]]
		+	[[Category: Pyridoxal phosphate]]
		+	[[Category: Pyridoxal-5'-phosphate dependent racemase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:06:58 2009''