2zxo - Revision history

OCA at 14:01, 1 November 2023

OCA — Wed, 01 Nov 2023 14:01:06 GMT

←Older revision		Revision as of 14:01, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='2zxo' size='340' side='right'caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2zxo' size='340' side='right'caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2zxp\|2zxp]], [[2zxr\|2zxr]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">recj, TTHA1167 ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&~~id=300852 THET8])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [https://pdbe.org/2zxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [https://www.ebi.ac.uk/pdbsum/2zxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [https://pdbe.org/2zxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [https://www.ebi.ac.uk/pdbsum/2zxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RECJ_THET8 RECJ_THET8]] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.<ref>PMID:21087930</ref>	+	[https://www.uniprot.org/uniprot/RECJ_THET8 RECJ_THET8] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.<ref>PMID:21087930</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thet8~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Kitamura, Y]]	+	[[Category: Kitamura Y]]
-	[[Category: Kuramitsu, S]]	+	[[Category: Kuramitsu S]]
-	[[Category: Masui, R]]	+	[[Category: Masui R]]
-	[[Category: Nakagawa, N]]	+	[[Category: Nakagawa N]]
-	[[Category: Wakamatsu, T]]	+	[[Category: Wakamatsu T]]
-	~~[[Category: Dna repair]]~~	+
-	~~[[Category: Exonuclease]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Nuclease]]~~	+
-	~~[[Category: Single-stranded dna~~]]	+

OCA at 16:10, 22 December 2021

OCA — Wed, 22 Dec 2021 16:10:20 GMT

←Older revision		Revision as of 16:10, 22 December 2021
Line 1:		Line 1:

	==Crystal structure of RecJ from Thermus thermophilus HB8==		==Crystal structure of RecJ from Thermus thermophilus HB8==
-	<StructureSection load='2zxo' size='340' side='right' caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2zxo' size='340' side='right'caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zxp\|2zxp]], [[2zxr\|2zxr]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [~~http~~://pdbe.org/2zxo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2zxo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [https://pdbe.org/2zxo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [https://www.ebi.ac.uk/pdbsum/2zxo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RECJ_THET8 RECJ_THET8]] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.<ref>PMID:21087930</ref>	+	[[https://www.uniprot.org/uniprot/RECJ_THET8 RECJ_THET8]] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.<ref>PMID:21087930</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Exonuclease\|Exonuclease]]	+	*[[Exonuclease 3D structures\|Exonuclease 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Kitamura, Y]]		[[Category: Kitamura, Y]]

OCA at 07:15, 18 October 2018

OCA — Thu, 18 Oct 2018 07:15:06 GMT

←Older revision		Revision as of 07:15, 18 October 2018
Line 1:		Line 1:
		+
	==Crystal structure of RecJ from Thermus thermophilus HB8==		==Crystal structure of RecJ from Thermus thermophilus HB8==
	<StructureSection load='2zxo' size='340' side='right' caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2zxo' size='340' side='right' caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://pdbe.org/2zxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://pdbe.org/2zxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zxo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zxo_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zxo_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:11, 8 February 2016

OCA — Mon, 08 Feb 2016 06:11:59 GMT

←Older revision		Revision as of 06:11, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='2zxo' size='340' side='right' caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2zxo' size='340' side='right' caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~274 Thermus thermophilus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://pdbe.org/2zxo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~Q5SJ47_THET8 Q5SJ47_THET8~~]] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.	+	[[http://www.uniprot.org/uniprot/RECJ_THET8 RECJ_THET8]] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.<ref>PMID:21087930</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zxo ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2zxo" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermus thermophilus~~]]	+	[[Category: Thet8]]
	[[Category: Kitamura, Y]]		[[Category: Kitamura, Y]]
	[[Category: Kuramitsu, S]]		[[Category: Kuramitsu, S]]

OCA at 21:13, 24 December 2014

OCA — Wed, 24 Dec 2014 21:13:15 GMT

←Older revision		Revision as of 21:13, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q5SJ47_THET8 Q5SJ47_THET8]] Single-stranded-DNA-specific exonuclease acting in a 5' to 3' direction; has no detectable activity on ssRNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Kitamura, Y.]]	+	[[Category: Kitamura, Y]]
-	[[Category: Kuramitsu, S.]]	+	[[Category: Kuramitsu, S]]
-	[[Category: Masui, R.]]	+	[[Category: Masui, R]]
-	[[Category: Nakagawa, N.]]	+	[[Category: Nakagawa, N]]
-	[[Category: Wakamatsu, T.]]	+	[[Category: Wakamatsu, T]]
	[[Category: Dna repair]]		[[Category: Dna repair]]
	[[Category: Exonuclease]]		[[Category: Exonuclease]]

OCA at 09:01, 29 September 2014

OCA — Mon, 29 Sep 2014 09:01:45 GMT

←Older revision		Revision as of 09:01, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2zxo.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of RecJ from Thermus thermophilus HB8==
		+	<StructureSection load='2zxo' size='340' side='right' caption='[[2zxo]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2zxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZXO FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zxp\|2zxp]], [[2zxr\|2zxr]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">recj, TTHA1167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zxo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2zxo RCSB], [http://www.ebi.ac.uk/pdbsum/2zxo PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zx/2zxo_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	RecJ is a single-stranded DNA (ssDNA)-specific 5'-3' exonuclease that plays an important role in DNA repair and recombination. To elucidate how RecJ achieves its high specificity for ssDNA, we determined the entire structures of RecJ both in a ligand-free form and in a complex with Mn(2+) or Mg(2+) by x-ray crystallography. The entire RecJ consists of four domains that form a molecule with an O-like structure. One of two newly identified domains had structural similarities to an oligonucleotide/oligosaccharide-binding (OB) fold. The OB fold domain alone could bind to DNA, indicating that this domain is a novel member of the OB fold superfamily. The truncated RecJ containing only the core domain exhibited much lower affinity for the ssDNA substrate compared with intact RecJ. These results support the hypothesis that these structural features allow specific binding of RecJ to ssDNA. In addition, the structure of the RecJ-Mn(2+) complex suggests that the hydrolysis reaction catalyzed by RecJ proceeds through a two-metal ion mechanism.

-	~~{{STRUCTURE_2zxo\| PDB=2zxo \| SCENE= }}~~	+	Structure of RecJ exonuclease defines its specificity for single-stranded DNA.,Wakamatsu T, Kitamura Y, Kotera Y, Nakagawa N, Kuramitsu S, Masui R J Biol Chem. 2010 Mar 26;285(13):9762-9. Epub 2010 Feb 2. PMID:20129927<ref>PMID:20129927</ref>

-	~~===Crystal structure~~ of ~~RecJ from Thermus thermophilus HB8===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20129927}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2zxo]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].~~	+

	==See Also==		==See Also==
	*[[Exonuclease\|Exonuclease]]		*[[Exonuclease\|Exonuclease]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020129927<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Kitamura, Y.]]		[[Category: Kitamura, Y.]]

OCA at 09:11, 20 October 2012

OCA — Sat, 20 Oct 2012 09:11:59 GMT

←Older revision		Revision as of 09:11, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2zxo]] is a 1 chain structure ~~of [[Exonuclease]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].	+	[[2zxo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].

	==See Also==		==See Also==

OCA: Protected "2zxo" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 22:04:52 GMT

Protected "2zxo" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:04, 25 July 2012

OCA at 22:04, 25 July 2012

OCA — Wed, 25 Jul 2012 22:04:50 GMT

←Older revision		Revision as of 22:04, 25 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2zxo.png\|left\|200px]]		[[Image:2zxo.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2zxo", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2zxo\| PDB=2zxo \| SCENE= }}		{{STRUCTURE_2zxo\| PDB=2zxo \| SCENE= }}

	===Crystal structure of RecJ from Thermus thermophilus HB8===		===Crystal structure of RecJ from Thermus thermophilus HB8===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20129927}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20129927 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20129927}}		{{ABSTRACT_PUBMED_20129927}}

	==About this Structure==		==About this Structure==
-	~~2ZXO~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].	+	[[2zxo]] is a 1 chain structure of [[Exonuclease]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].
		+
		+	==See Also==
		+	*[[Exonuclease\|Exonuclease]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20129927~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020129927</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Kitamura, Y.]]		[[Category: Kitamura, Y.]]
Line 35:		Line 26:
	[[Category: Nuclease]]		[[Category: Nuclease]]
	[[Category: Single-stranded dna]]		[[Category: Single-stranded dna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 08:42:49 2010''

OCA at 05:42, 21 April 2010

OCA — Wed, 21 Apr 2010 05:42:50 GMT

←Older revision		Revision as of 05:42, 21 April 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:2zxo.~~jpg~~\|left\|200px]]	+	[[Image:2zxo.png\|left\|200px]]

	<!--		<!--
Line 12:		Line 12:
	===Crystal structure of RecJ from Thermus thermophilus HB8===		===Crystal structure of RecJ from Thermus thermophilus HB8===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20129927}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20129927 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20129927}}

	==About this Structure==		==About this Structure==
-	2ZXO is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].	+	2ZXO is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZXO OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20129927</ref><references group="xtra"/>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Kitamura, Y.]]		[[Category: Kitamura, Y.]]
Line 27:		Line 36:
	[[Category: Single-stranded dna]]		[[Category: Single-stranded dna]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 6 09~~:33:26 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 08:42:49 2010''